Shantha Mahadevaiah

Paul S. Burgoyne (1946-2020)

Authors (4)

Development

Published 27 October 2020

Crick labs

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Human embryogenesis: A comparative perspective

Authors (5)

Annual Review of Cell and Developmental Biology

Published 6 October 2020

Crick labs

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A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation

Authors (4)

Nature

Published 22 October 2020

Crick labs/ facilities

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The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes

Authors (12)

Elias Elinati
Agata P Zielinska
Afshan McCarthy
Nada Kubikova
Valdone Maciulyte
Shantha Mahadevaiah
[...]
Andrew Ojarikre
Dagan Wells
Kathy Niakan
Melina Schuh
James Turner

Nature Communications

Published 25 May 2020

Crick labs/ facilities

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IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche

Authors (17)

Sissy E Wamaitha
Katarzyna J Grybel
Gregorio Alanis-Lobato
Claudia Gerri
Sugako Ogushi
Afshan McCarthy
[...]
Phil Snell
Leila Christie
Julian Downward
James Turner
Kathy Niakan

Nature Communications

Published 7 February 2020

Crick labs/ facilities

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SETDB1 links the meiotic DNA damage response to sex chromosome silencing in mice

Authors (11)

Takayuki Hirota
Paul Blakeley
Mahesh N Sangrithi
Shantha Mahadevaiah
Vesela Encheva
Bram Snijders
Elias Elinati
Obah A Ojarikre
Dirk G de Rooij
Kathy Niakan
James Turner

Developmental Cell

Published 3 December 2018

Crick labs/ facilities

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ATR is a multifunctional regulator of male mouse meiosis

Authors (16)

Alexander Widger
Shantha Mahadevaiah
Julian Lange
Elias Elinati
Jasmin Zohren
Takayuki Hirota
[...]
Dirk G de Rooij
Attila Tóth
Ignasi Roig
Scott Keeney
James Turner

Nature Communications

Published 5 July 2018

Crick labs

James Turner

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Fertile offspring from sterile sex chromosome trisomic mice

Authors (7)

Science

Published 1 September 2017

Crick labs/ facilities

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Non-canonical and sexually dimorphic X dosage compensation states in the mouse and human germline

Authors (9)

Mahesh N Sangrithi
Helene Royo
Shantha Mahadevaiah
Andrew Ojarikre
Leena Bhaw
Abdul Sesay
Antoine HFM Peters
Michael Stadler
James Turner

Developmental Cell

Published 6 February 2017

Crick labs/ facilities

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Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes

Authors (5)

Nadège Vernet
Shantha Mahadevaiah
Dirk G de Rooij
Paul S Burgoyne
Peter JI Ellis

Human Molecular Genetics

Published 13 October 2016

Crick labs/ facilities

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Mouse Y-encoded transcription factor Zfy2 is essential for sperm head remodelling and sperm tail development

Authors (7)

Nadege Vernet
Shantha Mahadevaiah
Fanny Decarpentrie
Guy Longepied
Dirk G de Rooij
Paul S Burgoyne
Michael J Mitchell

PLOS ONE

Published 14 June 2016

Crick labs/ facilities

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Mammalian meiotic silencing exhibits sexually dimorphic features

Authors (5)

JM Cloutier
Shantha Mahadevaiah
Elias Elinati
A Tóth
James Turner

Chromosoma

Published 1 June 2016

Crick labs/ facilities

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Histone H2AFX links meiotic chromosome asynapsis to prophase I oocyte loss in mammals

Authors (6)

Jeffrey M Cloutier
Shantha Mahadevaiah
Elias Elinati
André Nussenzweig
Attila Tóth
James Turner

PLOS Genetics

Published 28 October 2015

Crick labs/ facilities

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ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing

Authors (13)

Hélène Royo
Haydn Prosser
Yaroslava Ruzankina
Shantha Mahadevaiah
Jeffrey M Cloutier
Marek Baumann
[...]
Attila Tóth
Dirk G de Rooij
Allan Bradley
Eric J Brown
James Turner

Genes & Development

Published 1 January 2013

Crick labs

James Turner

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Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation

Authors (14)

J Grant
Shantha Mahadevaiah
P Khil
MN Sangrithi
H Royo
J Duckworth
[...]
Willie Taylor
G Elgar
RD Camerini-Otero
MJ Gilchrist
James Turner

Nature

Published 1 January 2012

Crick labs

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Evidence that meiotic sex chromosome inactivation is essential for male fertility

Authors (9)

H Royo
G Polikiewicz
Shantha Mahadevaiah
H Prosser
M Mitchell
A Bradley
DG de Rooij
PS Burgoyne
James Turner

Current Biology

Published 17 November 2010

Crick labs

James Turner

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Journal

Paul S. Burgoyne (1946-2020)

Human embryogenesis: A comparative perspective

A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation

The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes

IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche

SETDB1 links the meiotic DNA damage response to sex chromosome silencing in mice

ATR is a multifunctional regulator of male mouse meiosis

Fertile offspring from sterile sex chromosome trisomic mice

Non-canonical and sexually dimorphic X dosage compensation states in the mouse and human germline

Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes

Mouse Y-encoded transcription factor Zfy2 is essential for sperm head remodelling and sperm tail development

Mammalian meiotic silencing exhibits sexually dimorphic features

Histone H2AFX links meiotic chromosome asynapsis to prophase I oocyte loss in mammals

ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing

Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation

Evidence that meiotic sex chromosome inactivation is essential for male fertility

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