Vacancies Find links to current vacancies, and information about recruitment to various types of role.
Coronavirus (COVID-19) research Crick researchers are working at the forefront of the scientific response to answer some of the most urgent questions about the SARS-CoV-2 pathogen, from how we can improve testing, to why it’s deadly in some people but causes no symptoms in others.
Francis Crick Institute coronavirus (COVID-19) response The Francis Crick Institute is working at the forefront of the scientific response to coronavirus, volunteering expertise and facilities to help tackle the COVID-19 pandemic.
Stiaan LabuschagneLab: p53 and Metabolism LaboratoryJob Title: Postdoc Email Address: Email Breadcrumb Home Research Researchers Stiaan Labuschagne Year published2020 (1)2019 (3)2018 (2)2017 (1)2016 (2)2015 (1)2014 (2) Facet Year publishedResearch topicsCell Biology (6)Metabolism (6)Signalling & Oncogenes (6) Facet Research topicsCrick Pre-CrickCrick publications (6)Pre-Crick publications (6) Facet Crick Pre-CrickPublication typeCommentary (1)Journal article (12)Method (2)Primary research (7)Review (2) Facet Publication typeJournalBiochimica et Biophysica Acta (1)Cancer Cell (1)Cell Metabolism (2)Cell Reports (1)Methods in Molecular Biology (2)Molecular Cell (2)Nature (1)Nature Reviews Molecular Cell Biology (1)Science advances (1) Facet Journal Displaying 1 - 12 of 12Last updated : 24 January 2021 03:48 Dynamic ROS control by TIGAR regulates the initiation and progression of pancreatic cancer Authors (7)Eric Cheung Gina M DeNicola Colin Nixon Karen BlythStiaan Labuschagne David A TuvesonKaren Vousden Cancer Cell Published 10 February 2020 Crick labsKaren VousdenFull details Cell clustering promotes a metabolic switch that supports metastatic colonization Authors (5)Stiaan LabuschagneEric CheungJulianna BlagihMarie-Charlotte DomartKaren Vousden Cell Metabolism Published 1 October 2019 Crick labs/ facilitiesKaren VousdenElectron MicroscopyMetabolomicsExperimental HistopathologyBiological Research FacilityFull details Use of 13C315N1-serine or 13C515N1-methionine for studying methylation dynamics in cancer cell metabolism and epigenetics Authors (4) Alice C NewmanStiaan LabuschagneKaren Vousden Oliver DK Maddocks Methods in Molecular Biology Published 7 February 2019 Crick labsKaren VousdenFull details Direct estimation of metabolic flux by heavy isotope labeling simultaneous with pathway inhibition: Metabolic flux inhibition assay Authors (4) Tong ZhangStiaan LabuschagneKaren Vousden Oliver DK Maddocks Methods in Molecular Biology Published 1 January 2019 Crick labsKaren VousdenFull details A role for p53 in the adaptation to glutamine starvation through the expression of SLC1A3 Authors (9)Mylene Tajan Andreas K HockJulianna Blagih Neil A RobertsonStiaan Labuschagne Flore Kruiswijk Timothy J Humpton Peter D AdamsKaren Vousden Cell Metabolism Published 6 November 2018 Crick labs/ facilitiesKaren VousdenMetabolomicsBiological Research FacilityFull details Control of metabolism by p53 - cancer and beyond Authors (3)Stiaan Labuschagne Fabio ZaniKaren Vousden Biochimica et Biophysica Acta Published 5 June 2018 Crick labsKaren VousdenFull details Modulating the therapeutic response of tumours to dietary serine and glycine starvation Authors (17) Oliver DK Maddocks Dimitris Athineos Eric C Cheung Pearl Lee Tong Zhang Niels JF van den Broek[...] Kirsteen J Campbell Fatih Ceteci Owen J Sansom Karen BlythKaren Vousden Nature Published 20 April 2017 Crick labsKaren VousdenFull details Serine one-carbon catabolism with formate overflow Authors (12) Johannes Meiser Sergey Tumanov Oliver MaddocksStiaan Labuschagne Dimitris Athineos Niels Van Den Broek[...] Eyal Gottlieb Karen BlythKaren Vousden Jurre J Kamphorst Alexei Vazquez Science advances Published 28 October 2016 Crick labsKaren VousdenFull details Serine metabolism supports the methionine cycle and DNA/RNA methylation through de novo ATP synthesis in cancer cells Authors (4) Oliver DK MaddocksStiaan Labuschagne Peter D AdamsKaren Vousden Molecular Cell Published 21 January 2016 Crick labsKaren VousdenFull details p53 in survival, death and metabolic health: a lifeguard with a licence to kill Authors (3) Flore KruiswijkStiaan LabuschagneKaren Vousden Nature Reviews Molecular Cell Biology Published 1 July 2015 Crick labsKaren VousdenFull details Localization of NADPH production: a wheel within a wheel Authors (3) Oliver DK MaddocksStiaan LabuschagneKaren Vousden Molecular Cell Published 17 July 2014 Crick labsKaren VousdenFull details Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells Authors (5)Stiaan Labuschagne Niels JF van den Broek Gillian M MackayKaren Vousden Oliver DK Maddocks Cell Reports Published 22 May 2014 Crick labsKaren VousdenFull details
Dynamic ROS control by TIGAR regulates the initiation and progression of pancreatic cancer Authors (7)Eric Cheung Gina M DeNicola Colin Nixon Karen BlythStiaan Labuschagne David A TuvesonKaren Vousden Cancer Cell Published 10 February 2020 Crick labsKaren VousdenFull details
Cell clustering promotes a metabolic switch that supports metastatic colonization Authors (5)Stiaan LabuschagneEric CheungJulianna BlagihMarie-Charlotte DomartKaren Vousden Cell Metabolism Published 1 October 2019 Crick labs/ facilitiesKaren VousdenElectron MicroscopyMetabolomicsExperimental HistopathologyBiological Research FacilityFull details
Use of 13C315N1-serine or 13C515N1-methionine for studying methylation dynamics in cancer cell metabolism and epigenetics Authors (4) Alice C NewmanStiaan LabuschagneKaren Vousden Oliver DK Maddocks Methods in Molecular Biology Published 7 February 2019 Crick labsKaren VousdenFull details
Direct estimation of metabolic flux by heavy isotope labeling simultaneous with pathway inhibition: Metabolic flux inhibition assay Authors (4) Tong ZhangStiaan LabuschagneKaren Vousden Oliver DK Maddocks Methods in Molecular Biology Published 1 January 2019 Crick labsKaren VousdenFull details
A role for p53 in the adaptation to glutamine starvation through the expression of SLC1A3 Authors (9)Mylene Tajan Andreas K HockJulianna Blagih Neil A RobertsonStiaan Labuschagne Flore Kruiswijk Timothy J Humpton Peter D AdamsKaren Vousden Cell Metabolism Published 6 November 2018 Crick labs/ facilitiesKaren VousdenMetabolomicsBiological Research FacilityFull details
Control of metabolism by p53 - cancer and beyond Authors (3)Stiaan Labuschagne Fabio ZaniKaren Vousden Biochimica et Biophysica Acta Published 5 June 2018 Crick labsKaren VousdenFull details
Modulating the therapeutic response of tumours to dietary serine and glycine starvation Authors (17) Oliver DK Maddocks Dimitris Athineos Eric C Cheung Pearl Lee Tong Zhang Niels JF van den Broek[...] Kirsteen J Campbell Fatih Ceteci Owen J Sansom Karen BlythKaren Vousden Nature Published 20 April 2017 Crick labsKaren VousdenFull details
Serine one-carbon catabolism with formate overflow Authors (12) Johannes Meiser Sergey Tumanov Oliver MaddocksStiaan Labuschagne Dimitris Athineos Niels Van Den Broek[...] Eyal Gottlieb Karen BlythKaren Vousden Jurre J Kamphorst Alexei Vazquez Science advances Published 28 October 2016 Crick labsKaren VousdenFull details
Serine metabolism supports the methionine cycle and DNA/RNA methylation through de novo ATP synthesis in cancer cells Authors (4) Oliver DK MaddocksStiaan Labuschagne Peter D AdamsKaren Vousden Molecular Cell Published 21 January 2016 Crick labsKaren VousdenFull details
p53 in survival, death and metabolic health: a lifeguard with a licence to kill Authors (3) Flore KruiswijkStiaan LabuschagneKaren Vousden Nature Reviews Molecular Cell Biology Published 1 July 2015 Crick labsKaren VousdenFull details
Localization of NADPH production: a wheel within a wheel Authors (3) Oliver DK MaddocksStiaan LabuschagneKaren Vousden Molecular Cell Published 17 July 2014 Crick labsKaren VousdenFull details
Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells Authors (5)Stiaan Labuschagne Niels JF van den Broek Gillian M MackayKaren Vousden Oliver DK Maddocks Cell Reports Published 22 May 2014 Crick labsKaren VousdenFull details
