Stiaan Labuschagne

Dynamic ROS control by TIGAR regulates the initiation and progression of pancreatic cancer

Authors (7)

Eric Cheung
Gina M DeNicola
Colin Nixon
Karen Blyth
Stiaan Labuschagne
David A Tuveson
Karen Vousden

Cancer Cell

Published 10 February 2020

Crick labs

Karen Vousden

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Cell clustering promotes a metabolic switch that supports metastatic colonization

Authors (5)

Cell Metabolism

Published 1 October 2019

Crick labs/ facilities

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Use of 13C315N1-serine or 13C515N1-methionine for studying methylation dynamics in cancer cell metabolism and epigenetics

Authors (4)

Alice C Newman
Stiaan Labuschagne
Karen Vousden
Oliver DK Maddocks

Methods in Molecular Biology

Published 7 February 2019

Crick labs

Karen Vousden

Full details

Direct estimation of metabolic flux by heavy isotope labeling simultaneous with pathway inhibition: Metabolic flux inhibition assay

Authors (4)

Tong Zhang
Stiaan Labuschagne
Karen Vousden
Oliver DK Maddocks

Methods in Molecular Biology

Published 1 January 2019

Crick labs

Karen Vousden

Full details

A role for p53 in the adaptation to glutamine starvation through the expression of SLC1A3

Authors (9)

Mylène Tajan
Andreas K Hock
Julianna Blagih
Neil A Robertson
Stiaan Labuschagne
Flore Kruiswijk
Timothy J Humpton
Peter D Adams
Karen Vousden

Cell Metabolism

Published 8 August 2018

Crick labs

Karen Vousden

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Control of metabolism by p53 - cancer and beyond

Authors (3)

Biochimica et Biophysica Acta

Published 5 June 2018

Crick labs

Karen Vousden

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Modulating the therapeutic response of tumours to dietary serine and glycine starvation

Authors (17)

Oliver DK Maddocks
Dimitris Athineos
Eric C Cheung
Pearl Lee
Tong Zhang
Niels JF van den Broek
[...]
Kirsteen J Campbell
Fatih Ceteci
Owen J Sansom
Karen Blyth
Karen Vousden

Nature

Published 1 January 2017

Crick labs

Karen Vousden

Full details

Serine one-carbon catabolism with formate overflow

Authors (12)

Johannes Meiser
Sergey Tumanov
Oliver Maddocks
Stiaan Labuschagne
Dimitris Athineos
Niels Van Den Broek
[...]
Eyal Gottlieb
Karen Blyth
Karen Vousden
Jurre J Kamphorst
Alexei Vazquez

Science advances

Published 1 October 2016

Crick labs

Karen Vousden

Full details

Serine metabolism supports the methionine cycle and DNA/RNA methylation through de novo ATP synthesis in cancer cells

Authors (4)

Oliver DK Maddocks
Stiaan Labuschagne
Peter D Adams
Karen Vousden

Molecular Cell

Published 21 January 2016

Crick labs

Karen Vousden

Full details

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

Authors (3)

Nature Reviews Molecular Cell Biology

Published 1 July 2015

Crick labs

Karen Vousden

Full details

Localization of NADPH production: a wheel within a wheel

Authors (3)

Molecular Cell

Published 17 July 2014

Crick labs

Karen Vousden

Full details

Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells

Authors (5)

Stiaan Labuschagne
Niels JF van den Broek
Gillian M Mackay
Karen Vousden
Oliver DK Maddocks

Cell Reports

Published 22 May 2014

Crick labs

Karen Vousden

Full details

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Stiaan Labuschagne

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Dynamic ROS control by TIGAR regulates the initiation and progression of pancreatic cancer

Cell clustering promotes a metabolic switch that supports metastatic colonization

Use of 13C315N1-serine or 13C515N1-methionine for studying methylation dynamics in cancer cell metabolism and epigenetics

Direct estimation of metabolic flux by heavy isotope labeling simultaneous with pathway inhibition: Metabolic flux inhibition assay

A role for p53 in the adaptation to glutamine starvation through the expression of SLC1A3

Control of metabolism by p53 - cancer and beyond

Modulating the therapeutic response of tumours to dietary serine and glycine starvation

Serine one-carbon catabolism with formate overflow

Serine metabolism supports the methionine cycle and DNA/RNA methylation through de novo ATP synthesis in cancer cells

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

Localization of NADPH production: a wheel within a wheel

Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells

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