Suzanne Claxton

Tracking gene expression of single mitochondria in live neurons using nanotweezers

Authors (12)

Annie Sahota
Binoy Paulose Nadappuram
Siân C Allerton
Flavie Lesept
Jack H Howden
Suzanne Claxton
[...]
Francesco A Aprile
Josef T Kittler
Mike Devine
Aleksandar P Ivanov
Joshua B Edel

Journal of the American Chemical Society

Published 24 June 2026

Crick labs/ facilities

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CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development

Preprint

Authors (21)

Simeon Mihaylov
Andre Teixeira Lopes
Margaux Silvestre
Gaia Bianchini
Helen R Flynn
Almaz Huseynova
[...]
Marcel Köhn
Mark Skehel
Jernej Ule
Florencia Iacaruso
Sila Ultanir

bioRxiv

Published 7 April 2026

Crick labs/ facilities

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Spatial and temporal single-cell profiling of RNA compartmentalization in neurons with nanotweezers

Authors (10)

Annie Sahota
Binoy Paulose Nadappuram
Zoe Kwan
Flavie Lesept
Jack H Howden
Suzanne Claxton
Josef T Kittler
Mike Devine
Joshua B Edel
Aleksandar P Ivanov

ACS Nano

Published 20 May 2025

Crick labs/ facilities

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CDKL5’s role in microtubule-based transport and cognitive function

Preprint

Authors (4)

Andre Teixeira Lopes
Ondine Janiv
Suzanne Claxton
Sila Ultanir

bioRxiv

Published 29 August 2024

Crick labs/ facilities

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Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain

Authors (5)

Molecular Psychiatry

Published 1 June 2024

Crick labs/ facilities

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Data associated with "Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain"

Authors (5)

Figshare

Published 15 January 2024

Crick labs/ facilities

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Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability

Authors (10)

Marisol Sampedro Castaneda
Lucas Baltussen
Andre Teixeira Lopes
Yichen Qiu
Liina Sirvio
Simeon Mihaylov
Suzanne Claxton
Jill C Richardson
Gabriele Lignani
Sila Ultanir

Nature Communications

Published 11 December 2023

Crick labs/ facilities

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Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration

Authors (14)

Flavia Roşianu
Simeon Mihaylov
Noreen Eder
Antonie Martiniuc
Suzanne Claxton
Helen R Flynn
[...]
Mark Skehel
Bram Snijders
Matthias Krause
Sharon Tooze
Sila Ultanir

Life Science Alliance

Published 1 February 2023

Crick labs/ facilities

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YAP1/TAZ drives ependymoma-like tumour formation in mice

Authors (15)

Noreen Eder
Federico Roncaroli
Marie-Charlotte Dolmart
Stuart Horswell
Felipe Andreiuolo
Helen Flynn
[...]
Jun-Hao Mao
Torsten Pietsch
Barry Thompson
Bram Snijders
Sila Ultanir

Nature Communications

Published 1 December 2020

Crick labs/ facilities

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Chemical genetic identification of GAK substrates reveals its role in regulating Na+/K+-ATPase

Authors (10)

Amy W Lin
Kalbinder K Gill
Marisol Sampedro Castaneda
Irene Matucci
Noreen Eder
Suzanne Claxton
Helen Flynn
Bram Snijders
Roger George
Sila Ultanir

Life Science Alliance

Published 31 December 2018

Crick labs/ facilities

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Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics

Authors (10)

Lucas Baltussen
Priscilla D Negraes
Margaux Silvestre
Suzanne Claxton
M Moeskops
Evangelos Christodoulou
Helen R Flynn
Bram Snijders
Alysson R Muotri
Sila Ultanir

EMBO Journal

Published 28 September 2018

Crick labs/ facilities

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MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development

Authors (9)

Sila Ultanir
Smita Yadav
Nicholas T Hertz
Juan A Oses-Prieto
Suzanne Claxton
Alma L Burlingame
Kevan M Shokat
Lily Y Jan
Yuh-Nung Jan

Neuron

Published 1 January 2014

Crick labs

Sila Ultanir

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Suzanne Claxton

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Ultanir lab

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Tracking gene expression of single mitochondria in live neurons using nanotweezers

CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development

Spatial and temporal single-cell profiling of RNA compartmentalization in neurons with nanotweezers

CDKL5’s role in microtubule-based transport and cognitive function

Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain

Data associated with "Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain"

Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability

Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration

YAP1/TAZ drives ependymoma-like tumour formation in mice

Chemical genetic identification of GAK substrates reveals its role in regulating Na+/K+-ATPase

Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics

MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development

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