Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
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Breadcrumb Research A Z researchers Suzanne Claxton SENIOR LABORATORY RESEARCH SCIENTIST Ultanir lab Kinases and Brain Development Laboratory Year published2023 (1)2020 (1)2018 (2) Facet Year publishedResearch topicsBiochemistry & Proteomics (4)Cell Biology (4)Chemical Biology & High Throughput (4)Computational & Systems Biology (4)Developmental Biology (4)Genetics & Genomics (1)Genome Integrity & Repair (1)Imaging (2)Model Organisms (2) (-)Neurosciences (4)Signalling & Oncogenes (4)Tumour Biology (1) Facet Research topicsPublication typeJournal article (4) (-)Primary research (4) Facet Publication typeJournalEMBO Journal (1)Life Sci Alliance (1)Life Science Alliance (1)Nature Communications (1) Facet JournalCrick Pre-CrickCrick publications (4) Facet Crick Pre-Crick Displaying 1 - 4 of 4Last updated : 23 March 2023 02:45 Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration Authors (14) Flavia RoşianuSimeon MihaylovNoreen Eder Antonie MartiniucSuzanne Claxton Helen R Flynn[...]Mark SkehelBram Snijders Matthias KrauseSharon ToozeSila Ultanir Life Sci Alliance Published 1 February 2023 Crick labs/ facilitiesSila UltanirSharon ToozeProteomicsElectron MicroscopyExperimental HistopathologyFull details YAP1/TAZ drives ependymoma-like tumour formation in mice Authors (15)Noreen Eder Federico Roncaroli Marie-Charlotte Dolmart Stuart Horswell Felipe Andreiuolo Helen Flynn[...] Jun-Hao Mao Torsten Pietsch Barry ThompsonBram SnijdersSila Ultanir Nature Communications Published 1 December 2020 Crick labs/ facilitiesSila UltanirBarry ThompsonProteomicsElectron MicroscopyBioinformatics and BiostatisticsFull details Chemical genetic identification of GAK substrates reveals its role in regulating Na+/K+-ATPase Authors (10) Amy W Lin Kalbinder K GillMarisol Sampedro Castaneda Irene MatucciNoreen EderSuzanne Claxton Helen FlynnBram SnijdersRoger GeorgeSila Ultanir Life Science Alliance Published 31 December 2018 Crick labs/ facilitiesSila UltanirStructural BiologyProteomicsLight MicroscopyGenetic Modification ServiceBiological Research FacilityFull details Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics Authors (10)Lucas Baltussen Priscilla D NegraesMargaux SilvestreSuzanne Claxton M Moeskops Evangelos Christodoulou Helen R FlynnBram Snijders Alysson R MuotriSila Ultanir EMBO Journal Published 28 September 2018 Crick labs/ facilitiesSila UltanirStructural BiologyProteomicsLight MicroscopyFull details
Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration Authors (14) Flavia RoşianuSimeon MihaylovNoreen Eder Antonie MartiniucSuzanne Claxton Helen R Flynn[...]Mark SkehelBram Snijders Matthias KrauseSharon ToozeSila Ultanir Life Sci Alliance Published 1 February 2023 Crick labs/ facilitiesSila UltanirSharon ToozeProteomicsElectron MicroscopyExperimental HistopathologyFull details
YAP1/TAZ drives ependymoma-like tumour formation in mice Authors (15)Noreen Eder Federico Roncaroli Marie-Charlotte Dolmart Stuart Horswell Felipe Andreiuolo Helen Flynn[...] Jun-Hao Mao Torsten Pietsch Barry ThompsonBram SnijdersSila Ultanir Nature Communications Published 1 December 2020 Crick labs/ facilitiesSila UltanirBarry ThompsonProteomicsElectron MicroscopyBioinformatics and BiostatisticsFull details
Chemical genetic identification of GAK substrates reveals its role in regulating Na+/K+-ATPase Authors (10) Amy W Lin Kalbinder K GillMarisol Sampedro Castaneda Irene MatucciNoreen EderSuzanne Claxton Helen FlynnBram SnijdersRoger GeorgeSila Ultanir Life Science Alliance Published 31 December 2018 Crick labs/ facilitiesSila UltanirStructural BiologyProteomicsLight MicroscopyGenetic Modification ServiceBiological Research FacilityFull details
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics Authors (10)Lucas Baltussen Priscilla D NegraesMargaux SilvestreSuzanne Claxton M Moeskops Evangelos Christodoulou Helen R FlynnBram Snijders Alysson R MuotriSila Ultanir EMBO Journal Published 28 September 2018 Crick labs/ facilitiesSila UltanirStructural BiologyProteomicsLight MicroscopyFull details
