Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Breadcrumb Research A Z researchers Thomas Miller Visiting Scientist Costa lab Macromolecular Machines Laboratory Email Address: Email Year published2022 (1)2019 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (2)Cell Biology (2)Cell Cycle & Chromosomes (2)Chemical Biology & High Throughput (1)Computational & Systems Biology (1)Genetics & Genomics (2)Genome Integrity & Repair (2)Imaging (2)Metabolism (1)Model Organisms (2)Structural Biology & Biophysics (2)Synthetic Biology (1) Facet Research topicsPublication typeJournal article (2) (-)Primary research (2) Facet Publication typeJournalNature (1)Nature Structural and Molecular Biology (1) Facet JournalCrick Pre-CrickCrick publications (2) Facet Crick Pre-Crick Displaying 1 - 2 of 2Last updated : 20 April 2024 02:18 Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase Authors (9)Julia GreiweThomas MillerJulia LockeFabrizio Martino Steven HowellAnne SchreiberAndrea NansJohn DiffleyAlessandro Costa Nature Structural and Molecular Biology Published 1 January 2022 Crick labs/ facilitiesAnne SchreiberJohn DiffleyAlessandro CostaStructural BiologyProteomicsFull details Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM Authors (5)Thomas MillerJulia LockeJulia GreiweJohn DiffleyAlessandro Costa Nature Published 20 November 2019 Crick labs/ facilitiesJohn DiffleyAlessandro CostaStructural BiologyFermentationElectron MicroscopyFull details
Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase Authors (9)Julia GreiweThomas MillerJulia LockeFabrizio Martino Steven HowellAnne SchreiberAndrea NansJohn DiffleyAlessandro Costa Nature Structural and Molecular Biology Published 1 January 2022 Crick labs/ facilitiesAnne SchreiberJohn DiffleyAlessandro CostaStructural BiologyProteomicsFull details
Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM Authors (5)Thomas MillerJulia LockeJulia GreiweJohn DiffleyAlessandro Costa Nature Published 20 November 2019 Crick labs/ facilitiesJohn DiffleyAlessandro CostaStructural BiologyFermentationElectron MicroscopyFull details