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Breadcrumb Research A-Z researchers Thomas Rees Principal Laboratory Research Scientist Hess lab Biological Inorganic Chemistry Laboratory Year published 2026 (3) 2025 (1) 2024 (2) 2023 (1) Facet Year published Research topics Biochemistry & Proteomics (6) Chemical Biology & High Throughput (6) Infectious Disease (3) Structural Biology & Biophysics (3) Facet Research topics Crick Pre-Crick Crick publications (7) Facet Crick Pre-Crick Publication type Journal article (6) Preprint (1) Primary research (5) Review (1) Facet Publication type Journal Angewandte Chemie (1) Angewandte Chemie International Edition (1) Chembiochem (1) chemRxiv (1) Journal of Biological Inorganic Chemistry (1) Journal of the American Chemical Society (2) Facet Journal Displaying 1 - 7 of 7Last updated : 15 August 2026 02:41 Proteome-wide target identification using reactive metallo-scaffolds (r-mS): A platform for metallodrug discovery Authors (16) Jessica Waters Harry Wilders George S Biggs Mika Kintzel Emma E Cawood Jonathan Bailey [...] Joanna Redmond Mark Skehel David House Jacob Bush Jeannine Hess Angewandte Chemie International Edition Published 10 July 2026 Crick labs/ facilities Jeannine Hess Proteomics Chemical Biology Full details Proteome‐wide target identification using reactive metallo‐scaffolds (r‐mS): A platform for metallodrug discovery Authors (16) Jessica Waters Harry Wilders George S Biggs Mika Kintzel Emma E Cawood Jonathan Bailey [...] Joanna Redmond Mark Skehel David House Jacob Bush Jeannine Hess Angewandte Chemie Published 10 July 2026 Crick labs/ facilities Jeannine Hess Proteomics Chemical Biology Full details Rationally designed ruthenium(II) complexes combat drug resistance in Staphylococcus aureus via type IIA topoisomerase inhibition Preprint Authors (24) Blake Ho Thomas Rees Mollie A Phillips Enkai Jin Evangelos Christodoulou Andrew G Purkiss [...] Michael Howell J Mark Sutton Svend Kjaer Dimitrios Evangelopoulos Jeannine Hess chemRxiv Published 1 April 2026 Crick labs/ facilities Jeannine Hess Structural Biology Screening and Automated Science Chemical Biology Bioinformatics and Biostatistics Genomics Full details Light-activated metal-dependent protein degradation: A heterobifunctional ruthenium(II) photosensitizer targeting New Delhi metallo-β-lactamase 1 Authors (23) Lars Stevens-Cullinane Thomas Rees Calum Evans Blake Ho Mika Kintzel Yew Mun Yip [...] Mark Skehel Manuel M Müller Eachan Johnson Maxie M Roessler Jeannine Hess Journal of the American Chemical Society Published 10 December 2025 Crick labs/ facilities Eachan Johnson Jeannine Hess Structural Biology Proteomics Screening and Automated Science Chemical Biology Full details Antibacterial activity of Au(I), Pt(II), and Ir(III) biotin conjugates prepared by the iClick reaction: influence of the metal coordination sphere on the biological activity Authors (10) Dominik Moreth Lars Stevens-Cullinane Thomas Rees Victoria VL Müller Adrien Pasquier Ok-Ryul Song Scott Warchal Michael Howell Jeannine Hess Ulrich Schatzschneider Journal of Biological Inorganic Chemistry Published 1 September 2024 Crick labs/ facilities Jeannine Hess Screening and Automated Science Structural Biology Full details Rapid peptide cyclization inspired by the modular logic of nonribosomal peptide synthetases Authors (13) Yaoyu Ding Edward Lambden Jessica Peate Lewis J Picken Thomas Rees Gustavo Perez-Ortiz [...] Thomas Hicks Jeannine Hess Martin B Ulmschneider Manuel M Müller Sarah M Barry Journal of the American Chemical Society Published 19 June 2024 Crick labs Jeannine Hess Full details Recent advances in metal complexes for antimicrobial photodynamic therapy Authors (3) Thomas Rees Blake Ho Jeannine Hess Chembiochem Published 15 August 2023 Crick labs Jeannine Hess Full details
Proteome-wide target identification using reactive metallo-scaffolds (r-mS): A platform for metallodrug discovery Authors (16) Jessica Waters Harry Wilders George S Biggs Mika Kintzel Emma E Cawood Jonathan Bailey [...] Joanna Redmond Mark Skehel David House Jacob Bush Jeannine Hess Angewandte Chemie International Edition Published 10 July 2026 Crick labs/ facilities Jeannine Hess Proteomics Chemical Biology Full details
Proteome‐wide target identification using reactive metallo‐scaffolds (r‐mS): A platform for metallodrug discovery Authors (16) Jessica Waters Harry Wilders George S Biggs Mika Kintzel Emma E Cawood Jonathan Bailey [...] Joanna Redmond Mark Skehel David House Jacob Bush Jeannine Hess Angewandte Chemie Published 10 July 2026 Crick labs/ facilities Jeannine Hess Proteomics Chemical Biology Full details
Rationally designed ruthenium(II) complexes combat drug resistance in Staphylococcus aureus via type IIA topoisomerase inhibition Preprint Authors (24) Blake Ho Thomas Rees Mollie A Phillips Enkai Jin Evangelos Christodoulou Andrew G Purkiss [...] Michael Howell J Mark Sutton Svend Kjaer Dimitrios Evangelopoulos Jeannine Hess chemRxiv Published 1 April 2026 Crick labs/ facilities Jeannine Hess Structural Biology Screening and Automated Science Chemical Biology Bioinformatics and Biostatistics Genomics Full details
Light-activated metal-dependent protein degradation: A heterobifunctional ruthenium(II) photosensitizer targeting New Delhi metallo-β-lactamase 1 Authors (23) Lars Stevens-Cullinane Thomas Rees Calum Evans Blake Ho Mika Kintzel Yew Mun Yip [...] Mark Skehel Manuel M Müller Eachan Johnson Maxie M Roessler Jeannine Hess Journal of the American Chemical Society Published 10 December 2025 Crick labs/ facilities Eachan Johnson Jeannine Hess Structural Biology Proteomics Screening and Automated Science Chemical Biology Full details
Antibacterial activity of Au(I), Pt(II), and Ir(III) biotin conjugates prepared by the iClick reaction: influence of the metal coordination sphere on the biological activity Authors (10) Dominik Moreth Lars Stevens-Cullinane Thomas Rees Victoria VL Müller Adrien Pasquier Ok-Ryul Song Scott Warchal Michael Howell Jeannine Hess Ulrich Schatzschneider Journal of Biological Inorganic Chemistry Published 1 September 2024 Crick labs/ facilities Jeannine Hess Screening and Automated Science Structural Biology Full details
Rapid peptide cyclization inspired by the modular logic of nonribosomal peptide synthetases Authors (13) Yaoyu Ding Edward Lambden Jessica Peate Lewis J Picken Thomas Rees Gustavo Perez-Ortiz [...] Thomas Hicks Jeannine Hess Martin B Ulmschneider Manuel M Müller Sarah M Barry Journal of the American Chemical Society Published 19 June 2024 Crick labs Jeannine Hess Full details
Recent advances in metal complexes for antimicrobial photodynamic therapy Authors (3) Thomas Rees Blake Ho Jeannine Hess Chembiochem Published 15 August 2023 Crick labs Jeannine Hess Full details
