Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
PhD student recruitment Applications for the 2023 PhD programme are now open until 12:00 noon (GMT) on Wednesday 22 March 2023
Coronavirus (COVID-19) research Crick researchers are working at the forefront of the scientific response to answer some of the most urgent questions about the SARS-CoV-2 pathogen, from how we can improve testing, to why it’s deadly in some people but causes no symptoms in others.
Breadcrumb Research A Z researchers Tom Calcraft SENIOR LABORATORY RESEARCH SCIENTIST Rosenthal lab Structural Biology of Cells and Viruses Year published2023 (1)2022 (2)2021 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (1)Cell Biology (4)Chemical Biology & High Throughput (2)Computational & Systems Biology (1)Genetics & Genomics (1)Imaging (4)Immunology (1)Infectious Disease (4)Model Organisms (4)Signalling & Oncogenes (1)Structural Biology & Biophysics (4) Facet Research topicsPublication typeJournal article (4)Primary research (3)Review (1) Facet Publication typeJournalCommunications Biology (1)Journal of Structural Biology (1)Microscopy (Oxf) (1)PLOS Biology (1) Facet JournalCrick Pre-CrickCrick publications (4) Facet Crick Pre-Crick Displaying 1 - 4 of 4Last updated : 21 March 2023 03:26 A succession of two viral lattices drives vaccinia virus assembly Authors (5)Miguel Hernandez GonzalezTom CalcraftAndrea NansPeter RosenthalMichael Way PLOS Biology Published 2 March 2023 Crick labs/ facilitiesMichael WayPeter RosenthalStructural BiologyScientific computingFull details Electron cryotomography of SARS-CoV-2 virions reveals cylinder-shaped particles with a double layer RNP assembly Authors (5)Lesley CalderTom CalcraftSaira Hussain Ruth HarveyPeter Rosenthal Communications Biology Published 10 November 2022 Crick labs/ facilitiesPeter RosenthalJohn McCauleyDavid LV BauerWorldwide Influenza CentreStructural BiologyScientific computingFull details Cryogenic electron microscopy approaches that combine images and tilt series Authors (2)Tom CalcraftPeter Rosenthal Microscopy (Oxf) Published 1 March 2022 Crick labsPeter RosenthalFull details Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism Authors (12) Teige RS Matthews-Palmer Nayim Gonzalez-RodriguezTom Calcraft Signe Lagercrantz Tobias Zachs Xiu-Jun Yu[...] David W HoldenAndrea NansPeter Rosenthal Sarah L Rouse Morgan Beeby Journal of Structural Biology Published 1 June 2021 Crick labs/ facilitiesPeter RosenthalStructural BiologyFull details
A succession of two viral lattices drives vaccinia virus assembly Authors (5)Miguel Hernandez GonzalezTom CalcraftAndrea NansPeter RosenthalMichael Way PLOS Biology Published 2 March 2023 Crick labs/ facilitiesMichael WayPeter RosenthalStructural BiologyScientific computingFull details
Electron cryotomography of SARS-CoV-2 virions reveals cylinder-shaped particles with a double layer RNP assembly Authors (5)Lesley CalderTom CalcraftSaira Hussain Ruth HarveyPeter Rosenthal Communications Biology Published 10 November 2022 Crick labs/ facilitiesPeter RosenthalJohn McCauleyDavid LV BauerWorldwide Influenza CentreStructural BiologyScientific computingFull details
Cryogenic electron microscopy approaches that combine images and tilt series Authors (2)Tom CalcraftPeter Rosenthal Microscopy (Oxf) Published 1 March 2022 Crick labsPeter RosenthalFull details
Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism Authors (12) Teige RS Matthews-Palmer Nayim Gonzalez-RodriguezTom Calcraft Signe Lagercrantz Tobias Zachs Xiu-Jun Yu[...] David W HoldenAndrea NansPeter Rosenthal Sarah L Rouse Morgan Beeby Journal of Structural Biology Published 1 June 2021 Crick labs/ facilitiesPeter RosenthalStructural BiologyFull details