Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
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Coronavirus (COVID-19) research Crick researchers are working at the forefront of the scientific response to answer some of the most urgent questions about the SARS-CoV-2 pathogen, from how we can improve testing, to why it’s deadly in some people but causes no symptoms in others.
Breadcrumb Research A Z researchers Tom Calcraft SENIOR LABORATORY RESEARCH SCIENTIST Rosenthal lab Structural Biology of Cells and Viruses Year published2023 (1)2022 (2)2021 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (1)Cell Biology (4)Chemical Biology & High Throughput (2)Computational & Systems Biology (1)Genetics & Genomics (1)Imaging (4)Immunology (1)Infectious Disease (4)Model Organisms (4)Signalling & Oncogenes (1)Structural Biology & Biophysics (4) Facet Research topicsPublication typeJournal article (4)Primary research (3)Review (1) Facet Publication typeJournalCommunications Biology (1)Journal of Structural Biology (1)Microscopy (Oxf) (1)PLOS Biology (1) Facet JournalCrick Pre-CrickCrick publications (4) Facet Crick Pre-Crick Displaying 1 - 4 of 4Last updated : 21 March 2023 03:26 A succession of two viral lattices drives vaccinia virus assembly Authors (5)Miguel Hernandez GonzalezTom CalcraftAndrea NansPeter RosenthalMichael Way PLOS Biology Published 2 March 2023 Crick labs/ facilitiesMichael WayPeter RosenthalStructural BiologyScientific computingFull details Electron cryotomography of SARS-CoV-2 virions reveals cylinder-shaped particles with a double layer RNP assembly Authors (5)Lesley CalderTom CalcraftSaira Hussain Ruth HarveyPeter Rosenthal Communications Biology Published 10 November 2022 Crick labs/ facilitiesPeter RosenthalJohn McCauleyDavid LV BauerWorldwide Influenza CentreStructural BiologyScientific computingFull details Cryogenic electron microscopy approaches that combine images and tilt series Authors (2)Tom CalcraftPeter Rosenthal Microscopy (Oxf) Published 1 March 2022 Crick labsPeter RosenthalFull details Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism Authors (12) Teige RS Matthews-Palmer Nayim Gonzalez-RodriguezTom Calcraft Signe Lagercrantz Tobias Zachs Xiu-Jun Yu[...] David W HoldenAndrea NansPeter Rosenthal Sarah L Rouse Morgan Beeby Journal of Structural Biology Published 1 June 2021 Crick labs/ facilitiesPeter RosenthalStructural BiologyFull details
A succession of two viral lattices drives vaccinia virus assembly Authors (5)Miguel Hernandez GonzalezTom CalcraftAndrea NansPeter RosenthalMichael Way PLOS Biology Published 2 March 2023 Crick labs/ facilitiesMichael WayPeter RosenthalStructural BiologyScientific computingFull details
Electron cryotomography of SARS-CoV-2 virions reveals cylinder-shaped particles with a double layer RNP assembly Authors (5)Lesley CalderTom CalcraftSaira Hussain Ruth HarveyPeter Rosenthal Communications Biology Published 10 November 2022 Crick labs/ facilitiesPeter RosenthalJohn McCauleyDavid LV BauerWorldwide Influenza CentreStructural BiologyScientific computingFull details
Cryogenic electron microscopy approaches that combine images and tilt series Authors (2)Tom CalcraftPeter Rosenthal Microscopy (Oxf) Published 1 March 2022 Crick labsPeter RosenthalFull details
Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism Authors (12) Teige RS Matthews-Palmer Nayim Gonzalez-RodriguezTom Calcraft Signe Lagercrantz Tobias Zachs Xiu-Jun Yu[...] David W HoldenAndrea NansPeter Rosenthal Sarah L Rouse Morgan Beeby Journal of Structural Biology Published 1 June 2021 Crick labs/ facilitiesPeter RosenthalStructural BiologyFull details
