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Breadcrumb Research A Z researchers Tony Fearns Principal Laboratory Research Scientist Gutierrez lab Host-Pathogen Interactions in Tuberculosis Laboratory Email Address: Email Selected Publications Mycobacterium tuberculosis cords within lymphatic endothelial cells to evade host immunity Authors (9) Thomas R LernerChristophe QuevalRachel LaiMatt RussellTony FearnsDaniel GreenwoodLucy CollinsonRobert WilkinsonMaximiliano Gutierrez JCI insight Published 21 May 2020 Crick labs/ facilitiesRobert J WilkinsonMaximiliano GutierrezElectron MicroscopyFull details LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages Authors (18) Anetta HärtlovaSusanne Herbst Julien Peltier Angela Rodgers Orsolya Bilkei‐GorzoTony Fearns[...] Jennifer Martinez Dario R Alessi Alastair D Reith Matthias TrostMaximiliano Gutierrez EMBO Journal Published 15 June 2018 Crick labsMaximiliano GutierrezFull details Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells Authors (6) Thomas R LernerChristophe QuevalTony Fearns Urska Repnik Gareth GriffithsMaximiliano Gutierrez BMC Biology Published 4 January 2018 Crick labsMaximiliano GutierrezFull details Year published2022 (1)2020 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (2)Cell Biology (2)Cell Cycle & Chromosomes (1)Chemical Biology & High Throughput (2)Computational & Systems Biology (2)Developmental Biology (2)Gene Expression (2)Genetics & Genomics (2)Genome Integrity & Repair (2)Human Biology & Physiology (2)Imaging (1)Immunology (2)Infectious Disease (2)Metabolism (2)Microfabrication & Bioengineering (1)Model Organisms (2)Neurosciences (1) (-)Signalling & Oncogenes (2)Stem Cells (1)Structural Biology & Biophysics (1)Synthetic Biology (1)Tumour Biology (2) Facet Research topicsPublication typeJournal article (2)Primary research (2) Facet Publication typeJournalNature Communications (1)The Lancet (1) Facet JournalCrick Pre-CrickCrick publications (2) Facet Crick Pre-Crick Displaying 1 - 2 of 2Last updated : 28 March 2024 02:38 Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism Authors (17)Claudio Bussi Tiaan HeunisEnrica PellegrinoElliott Bernard Nourdine BahMariana Silva Dos Santos[...]James MacraeMaria Greco Thomas Reinheckel Matthias TrostMaximiliano Gutierrez Nature Communications Published 28 November 2022 Crick labs/ facilitiesMaximiliano GutierrezJulian DownwardMetabolomicsBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyHuman Embryonic Stem CellElectron MicroscopyAdvanced SequencingFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Mycobacterium tuberculosis cords within lymphatic endothelial cells to evade host immunity Authors (9) Thomas R LernerChristophe QuevalRachel LaiMatt RussellTony FearnsDaniel GreenwoodLucy CollinsonRobert WilkinsonMaximiliano Gutierrez JCI insight Published 21 May 2020 Crick labs/ facilitiesRobert J WilkinsonMaximiliano GutierrezElectron MicroscopyFull details
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages Authors (18) Anetta HärtlovaSusanne Herbst Julien Peltier Angela Rodgers Orsolya Bilkei‐GorzoTony Fearns[...] Jennifer Martinez Dario R Alessi Alastair D Reith Matthias TrostMaximiliano Gutierrez EMBO Journal Published 15 June 2018 Crick labsMaximiliano GutierrezFull details
Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells Authors (6) Thomas R LernerChristophe QuevalTony Fearns Urska Repnik Gareth GriffithsMaximiliano Gutierrez BMC Biology Published 4 January 2018 Crick labsMaximiliano GutierrezFull details
Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism Authors (17)Claudio Bussi Tiaan HeunisEnrica PellegrinoElliott Bernard Nourdine BahMariana Silva Dos Santos[...]James MacraeMaria Greco Thomas Reinheckel Matthias TrostMaximiliano Gutierrez Nature Communications Published 28 November 2022 Crick labs/ facilitiesMaximiliano GutierrezJulian DownwardMetabolomicsBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyHuman Embryonic Stem CellElectron MicroscopyAdvanced SequencingFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details