Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
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Breadcrumb Research A Z researchers Valdone Maciulyte PRINCIPAL LABORATORY RESEARCH SCIENTIST Turner lab Sex Chromosome Biology Laboratory Year published2021 (1)2020 (1)2018 (1)2017 (1) Facet Year publishedResearch topicsCell Biology (4)Cell Cycle & Chromosomes (4)Developmental Biology (4)Gene Expression (4)Genetics & Genomics (4)Genome Integrity & Repair (4)Human Biology & Physiology (4)Model Organisms (4)Stem Cells (4) Facet Research topicsPublication typeJournal article (4)Primary research (4) Facet Publication typeJournalNature (1)Nature Communications (3) Facet JournalCrick Pre-CrickCrick publications (4) Facet Crick Pre-Crick Displaying 1 - 4 of 4Last updated : 29 March 2023 03:01 CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes Authors (8)Charlotte DouglasValdone MaciulyteJasmin ZohrenDaniel SnellShantha MahadevaiahAndrew Ojarikre Peter JI EllisJames Turner Nature Communications Published 3 December 2021 Crick labs/ facilitiesJames TurnerLight MicroscopyIn Vivo ImagingGenetic Modification ServiceFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes Authors (12)Elias Elinati Agata P ZielinskaAfshan Mccarthy Nada KubikovaValdone MaciulyteShantha Mahadevaiah[...]Andrew Ojarikre Dagan WellsKathy Niakan Melina SchuhJames Turner Nature Communications Published 25 May 2020 Crick labs/ facilitiesJames TurnerKathy NiakanLight MicroscopyExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details ATR is a multifunctional regulator of male mouse meiosis Authors (16) Alexander WidgerShantha Mahadevaiah Julian LangeElias ElinatiJasmin ZohrenTakayuki Hirota[...] Dirk G de Rooij Attila Tóth Ignasi Roig Scott KeeneyJames Turner Nature Communications Published 5 July 2018 Crick labsJames TurnerFull details Genome editing reveals a role for OCT4 in human embryogenesis Authors (18)Norah FogartyAfshan Mccarthy Kirsten E SnijdersBenjamin Powell Nada Kubikova Paul Blakeley[...] Dagan Wells Ludovic Vallier Alessandro BerteroJames TurnerKathy Niakan Nature Published 5 October 2017 Crick labs/ facilitiesJames TurnerKathy NiakanBioinformatics and BiostatisticsLight MicroscopyHigh Throughput ScreeningBiological Research FacilityFull details
CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes Authors (8)Charlotte DouglasValdone MaciulyteJasmin ZohrenDaniel SnellShantha MahadevaiahAndrew Ojarikre Peter JI EllisJames Turner Nature Communications Published 3 December 2021 Crick labs/ facilitiesJames TurnerLight MicroscopyIn Vivo ImagingGenetic Modification ServiceFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes Authors (12)Elias Elinati Agata P ZielinskaAfshan Mccarthy Nada KubikovaValdone MaciulyteShantha Mahadevaiah[...]Andrew Ojarikre Dagan WellsKathy Niakan Melina SchuhJames Turner Nature Communications Published 25 May 2020 Crick labs/ facilitiesJames TurnerKathy NiakanLight MicroscopyExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
ATR is a multifunctional regulator of male mouse meiosis Authors (16) Alexander WidgerShantha Mahadevaiah Julian LangeElias ElinatiJasmin ZohrenTakayuki Hirota[...] Dirk G de Rooij Attila Tóth Ignasi Roig Scott KeeneyJames Turner Nature Communications Published 5 July 2018 Crick labsJames TurnerFull details
Genome editing reveals a role for OCT4 in human embryogenesis Authors (18)Norah FogartyAfshan Mccarthy Kirsten E SnijdersBenjamin Powell Nada Kubikova Paul Blakeley[...] Dagan Wells Ludovic Vallier Alessandro BerteroJames TurnerKathy Niakan Nature Published 5 October 2017 Crick labs/ facilitiesJames TurnerKathy NiakanBioinformatics and BiostatisticsLight MicroscopyHigh Throughput ScreeningBiological Research FacilityFull details
