William Grey

The CKS1/CKS2 proteostasis axis is crucial to maintain hematopoietic stem cell function

Authors (11)

William Grey
Samantha Atkinson
Beatrice Rix
Pedro Casado
Linda Ariza-Mcnaughton
Cathy Hawley
Miriam L Sopoena
Katherine S Bridge
David Kent
Pedro R Cutillas
Dominique Bonnet

HemaSphere

Published 1 March 2023

Crick labs/ facilities

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CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia

Authors (14)

William Grey
Ana Rio-Machin
Pedro Casado
Eva Gronroos
Sara Ali
Juho J Miettinen
[...]
Charles Swanton
Pedro R Cutillas
John Gribben
Jude Fitzgibbon
Dominique Bonnet

Science Translational Medicine

Published 22 June 2022

Crick labs/ facilities

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Human erythroid progenitors are directly infected by SARS-CoV-2: Implications for emerging erythropoiesis in severe COVID-19 patients

Authors (11)

Stem Cell Reports

Published 9 March 2021

Crick labs/ facilities

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Understanding of the crosstalk between normal residual hematopoietic stem cells and the leukemic niche in acute myeloid leukemia

Authors (3)

Experimental Hematology

Published 1 March 2021

Crick labs

Dominique Bonnet

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Activation of the receptor tyrosine kinase RET improves long-term hematopoietic stem cell outgrowth and potency

Authors (7)

Blood

Published 26 November 2020

Crick labs/ facilities

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Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis

Authors (17)

Nature Communications

Published 14 April 2020

Crick labs/ facilities

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Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches

Authors (6)

Ander Abarrategi
Syed Mian
Diana Passaro
Kevin Rouault-Pierre
William Grey
Dominique Bonnet

Journal of Experimental Medicine

Published 5 March 2018

Crick labs

Dominique Bonnet

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The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia

Authors (9)

Alessandro Di Tullio
Kevin Rouault-Pierre
Ander Abarrategi
Syed Mian
William Grey
John Gribben
Aengus Stewart
Elizabeth Blackwood
Dominique Bonnet

Nature Communications

Published 22 November 2017

Crick labs/ facilities

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The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukemia cell viability

Authors (8)

William Grey
Adam Ivey
Thomas A Milne
Torsten Haferlach
David Grimwade
Frank Uhlmann
Edwige Voisset
Veronica Yu

Biochimica et Biophysica Acta

Published 1 January 2018

Crick labs

Frank Uhlmann

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Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

Authors (18)

Borbala Mifsud
Filipe Tavares-Cadete
Alice N Young
Robert Sugar
Stefan Schoenfelder
Lauren Ferreira
[...]
Emily LeProust
George A Follows
Peter Fraser
Nicholas Luscombe
Cameron S Osborne

Nature Genetics

Published 1 June 2015

Crick labs

Nicholas Luscombe

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Research case studies

Vacancies

Cut + Paste exhibition

From local to global: preparing for the next pandemic

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William Grey

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The CKS1/CKS2 proteostasis axis is crucial to maintain hematopoietic stem cell function

CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia

Human erythroid progenitors are directly infected by SARS-CoV-2: Implications for emerging erythropoiesis in severe COVID-19 patients

Understanding of the crosstalk between normal residual hematopoietic stem cells and the leukemic niche in acute myeloid leukemia

Activation of the receptor tyrosine kinase RET improves long-term hematopoietic stem cell outgrowth and potency

Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis

Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches

The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia

The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukemia cell viability

Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

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