Ying Zhang

Lab: Structural Biology of Disease Processes Laboratory
Job Title: Senior Laboratory Research Scientist

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Last updated : 01 March 2021 02:49

The structure of the RbBP5 β-propeller domain reveals a surface with potential nucleic acid binding sites

Authors (7)

Anshumali Mittal
Fruzsina Hobor
Ying Zhang
Stephen R Martin
Steve Gamblin
Andres Ramos
Jon Wilson

Nucleic Acids Research

Published 20 April 2018

Crick labs/ facilities

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Identification of (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a potent and selective inhibitor of histone methyltransferase EZH2, suitabl

Authors (25)

Rishi G Vaswani
Victor S Gehling
Les A Dakin
Andrew S Cook
Christopher G Nasveschuk
Martin Duplessis
[...]
Ying Zhang
Neil Justin
Shuyang Chen
Jon Wilson
Steve Gamblin

Journal of Medicinal Chemistry

Published 10 November 2016

Crick labs

Steve Gamblin

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Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2

Authors (12)

Neil Justin
Ying Zhang
Cataldo Tarricone
Stephen R Martin
Shuyang Chen
Elizabeth Underwood
[...]
Lesley F Haire
Philip Walker
Danny Reinberg
Jon Wilson
Steve Gamblin

Nature Communications

Published 28 April 2016

Crick labs/ facilities

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Evolving catalytic properties of the MLL family SET domain

Authors (6)

Ying Zhang
Anshumali Mittal
James Reid
Stephanie Reich
Steve Gamblin
Jon Wilson

Structure

Published 6 October 2015

Crick labs

Steve Gamblin

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Ying Zhang

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The structure of the RbBP5 β-propeller domain reveals a surface with potential nucleic acid binding sites

Identification of (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a potent and selective inhibitor of histone methyltransferase EZH2, suitabl

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2

Evolving catalytic properties of the MLL family SET domain

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