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Breadcrumb Alex Gould Gould lab Physiology and Metabolism Laboratory : Publications Lab contentLab contentIn this section Overview Lab social gallery Areas of interest Lab news Publications Members Vacancies Lipid droplets (shown in green) can build up in cells from malnourished humans and other animals, image captured at the Crick by Annick Sawala and Alex Gould. Toggle to view hero caption PublicationsYear published2023 (2)2021 (1)2020 (1)2019 (1)2017 (1)2015 (1) Facet Year publishedResearch topicsDevelopmental Biology (7)Genetics & Genomics (7)Metabolism (7)Model Organisms (7)Neurosciences (7)Stem Cells (7)Tumour Biology (7)Biochemistry & Proteomics (6)Cell Biology (6)Human Biology & Physiology (6)Immunology (6)Infectious Disease (6)Signalling & Oncogenes (6)Chemical Biology & High Throughput (2)Genome Integrity & Repair (1)Synthetic Biology (1) (-)Computational & Systems Biology (7) Facet Research topicsPublication typeJournal article (7)Primary research (6)Review (1) Facet Publication typeJournalAngewandte Chemie International Edition (1)Annals of the New York Academy of Sciences (1)Cell (1)Developmental Cell (1)Journal of Proteome Research (1)Nature (1)Nature Communications (1) Facet Journal Publications Displaying 1 - 7 of 7Last updated : 24 April 2024 02:47 Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells Authors (14) Valeria Amodeo Timothy Davies Amalia Martinez-Segura Melanie P Clements Holly Simpson RagdaleAndrew Bailey[...] Holger Kramer Claudia Garcia-DiazAlex Gould Samuel Marguerat Simona Parrinello Developmental Cell Published 22 May 2023 Crick labs/ facilitiesAlex GouldMetabolomicsFull details The dietary sweetener sucralose is a negative modulator of T cell-mediated responses Authors (16)Fabio ZaniJulianna Blagih Tim GruberMichael Buck Nicholas JonesMarc Hennequart[...]Eric Cheung Ian S GilmoreAlex Gould Cristina Garcia-CaceresKaren Vousden Nature Published 23 March 2023 Crick labs/ facilitiesKaren VousdenCaetano Reis e SousaAlex GouldMetabolomicsBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details Metabolic decisions in development and disease-a Keystone Symposia report Authors (25) Jennifer Cable Olivier Pourquié Kathryn E Wellen Lydia WS Finley Alexander AulehlaAlex Gould[...] Navdeep S Chandel Jared Rutter Jason W Locasale Juan C Landoni Heather Christofk Annals of the New York Academy of Sciences Published 1 December 2021 Crick labsMarkus RalserIrene Miguel-AliagaAlex GouldFull details Cryogenic OrbiSIMS localizes semi-volatile molecules in biological tissues Authors (5)Clare Newell Jean-Luc VorngJames Macrae Ian S GilmoreAlex Gould Angewandte Chemie International Edition Published 5 October 2020 Crick labs/ facilitiesAlex GouldMetabolomicsTranslation teamMedia PreparationFull details An improved method for measuring absolute metabolite concentrations in small biofluid or tissue samples Authors (5) Tharindu Fernando Annick SawalaAndrew BaileyAlex GouldPaul Driscoll Journal of Proteome Research Published 13 February 2019 Crick labs/ facilitiesAlex GouldMetabolomicsMRC Biomedical NMR CentreFull details Developmental diet regulates Drosophila lifespan via lipid autotoxins Authors (7) M Irina StefanaPaul Driscoll Fumiaki Obata Ana Raquel PengellyClare NewellJames MacraeAlex Gould Nature Communications Published 9 November 2017 Crick labs/ facilitiesAlex GouldMetabolomicsMRC Biomedical NMR CentreFull details Antioxidant role for lipid droplets in a stem cell niche of Drosophila Authors (8)Andrew Bailey Grielof Koster Christelle Guillermier Elizabeth MA HirstJames Macrae Claude P Lechene Anthony D PostleAlex Gould Cell Published 8 October 2015 Crick labs/ facilitiesAlex GouldMetabolomicsElectron MicroscopyFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells Authors (14) Valeria Amodeo Timothy Davies Amalia Martinez-Segura Melanie P Clements Holly Simpson RagdaleAndrew Bailey[...] Holger Kramer Claudia Garcia-DiazAlex Gould Samuel Marguerat Simona Parrinello Developmental Cell Published 22 May 2023 Crick labs/ facilitiesAlex GouldMetabolomicsFull details
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses Authors (16)Fabio ZaniJulianna Blagih Tim GruberMichael Buck Nicholas JonesMarc Hennequart[...]Eric Cheung Ian S GilmoreAlex Gould Cristina Garcia-CaceresKaren Vousden Nature Published 23 March 2023 Crick labs/ facilitiesKaren VousdenCaetano Reis e SousaAlex GouldMetabolomicsBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Metabolic decisions in development and disease-a Keystone Symposia report Authors (25) Jennifer Cable Olivier Pourquié Kathryn E Wellen Lydia WS Finley Alexander AulehlaAlex Gould[...] Navdeep S Chandel Jared Rutter Jason W Locasale Juan C Landoni Heather Christofk Annals of the New York Academy of Sciences Published 1 December 2021 Crick labsMarkus RalserIrene Miguel-AliagaAlex GouldFull details
Cryogenic OrbiSIMS localizes semi-volatile molecules in biological tissues Authors (5)Clare Newell Jean-Luc VorngJames Macrae Ian S GilmoreAlex Gould Angewandte Chemie International Edition Published 5 October 2020 Crick labs/ facilitiesAlex GouldMetabolomicsTranslation teamMedia PreparationFull details
An improved method for measuring absolute metabolite concentrations in small biofluid or tissue samples Authors (5) Tharindu Fernando Annick SawalaAndrew BaileyAlex GouldPaul Driscoll Journal of Proteome Research Published 13 February 2019 Crick labs/ facilitiesAlex GouldMetabolomicsMRC Biomedical NMR CentreFull details
Developmental diet regulates Drosophila lifespan via lipid autotoxins Authors (7) M Irina StefanaPaul Driscoll Fumiaki Obata Ana Raquel PengellyClare NewellJames MacraeAlex Gould Nature Communications Published 9 November 2017 Crick labs/ facilitiesAlex GouldMetabolomicsMRC Biomedical NMR CentreFull details
Antioxidant role for lipid droplets in a stem cell niche of Drosophila Authors (8)Andrew Bailey Grielof Koster Christelle Guillermier Elizabeth MA HirstJames Macrae Claude P Lechene Anthony D PostleAlex Gould Cell Published 8 October 2015 Crick labs/ facilitiesAlex GouldMetabolomicsElectron MicroscopyFull details