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Breadcrumb Andrea Serio Serio lab Neural Circuit Bioengineering and Disease Modelling Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Lab members Publications PublicationsCrick/Pre-CrickCrick publications (9)Pre-Crick publications (11) Facet Crick/Pre-Crick Publications Displaying 1 - 20 of 20Last updated : 28 November 2023 02:09 Biophysical regulations of epigenetic state and notch signaling in neural development using microgroove substrates Authors (7) Chia-Chen HsuAndrea Serio Sahana Gopal Amy Gelmi Ciro Chiappini Ravi A Desai Molly M Stevens ACS Applied Materials and Interfaces Published 13 July 2022 Crick labsAndrea SerioFull details Bioengineering human skeletal muscle models: Recent advances, current challenges and future perspectives Authors (5) Yunsong Jiang Tugce Torun Sara M MaffiolettiAndrea SerioFrancesco Saverio Tedesco Experimental Cell Research Published 15 July 2022 Crick labsFrancesco Saverio TedescoAndrea SerioFull details Axonal length determines distinct homeostatic phenotypes in human iPSC derived motor neurons on a bioengineered platform Authors (8)Cathleen Hagemann Carmen Moreno GonzalezLudovica GuettaGiulia Tyzack Ciro Chiappini Andrea LegatiRickie PataniAndrea Serio Advanced Healthcare Materials Published 18 May 2022 Crick labsAndrea SerioRickie PataniFull details Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2 Authors (17) Antonette Bennett Joshua Hull Nelly Jolinon Julie Tordo Katie Moss Enswert Binns[...] Felix Broecker Peter Seeberger Els Henckaerts Robert McKenna Mavis Agbandje-McKenna Journal of Structural Biology Published 1 December 2021 Crick labsAndrea SerioFull details TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain Authors (4)Jasmine HarleyCathleen HagemannAndrea SerioRickie Patani Brain Communications Published 6 August 2021 Crick labsAndrea SerioRickie PataniFull details Unsupervised cell segmentation and labelling in neural tissue images Authors (9) S Iglesias-Rey F Antunes-SantosCathleen Hagemann D Gómez-Cabrero H BustinceRickie PataniAndrea Serio B De Baets C Lopez-Molina Applied Sciences (Switzerland) Published 21 April 2021 Crick labsAndrea SerioRickie PataniFull details Automated and unbiased discrimination of ALS from control tissue at single cell resolution Authors (9)Cathleen HagemannGiulia TyzackDoaa Taha Helen Devine Linda Greensmith Jia NewcombeRickie PataniAndrea Serio Raphaëlle Luisier Brain Pathology Published 1 July 2021 Crick labsAndrea SerioRickie PataniFull details FUS is lost from nuclei and gained in neurites of motor neurons in a human stem cell model of VCP-related ALS Authors (4)Jasmine HarleyCathleen HagemannAndrea SerioRickie Patani Brain Published 1 December 2020 Crick labsAndrea SerioRickie PataniFull details An electroactive oligo‐EDOT platform for neural tissue engineering Authors (10) Kaja I Ritzau‐Reid Christopher D Spicer Amy Gelmi Christopher L Grigsby James F Ponder Victoria Bemmer Adam Creamer Ramon VilarAndrea Serio Molly M Stevens Advanced Functional Materials Published 15 October 2020 Crick labsAndrea SerioFull details Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS Authors (11) Kaitlin Weskamp Elizabeth M Tank Roberto Miguez Jonathon P McBride Nicolás B Gómez Matthew White Ziqiang LinCarmen Moreno GonzalezAndrea Serio Jemeen Sreedharan Sami J Barmada Journal of Clinical Investigation Published 2 March 2020 Crick labsAndrea SerioFull details Raman spectroscopy: Guiding light for the extracellular matrix Authors (3) Mads S BergholtAndrea Serio Michael B Albro Frontiers in Bioengineering and Biotechnology Published 1 November 2019 Crick labsAndrea SerioFull details Immunogold FIB-SEM: Combining volumetric ultrastructure visualization with 3D biomolecular analysis to dissect cell-environment interactions Authors (11) Sahana Gopal Ciro Chiappini James PK Armstrong Qu ChenAndrea Serio Chia-Chen Hsu Christoph Meinert Travis J Klein Dietmar W Hutmacher Stephen Rothery Molly M Stevens Advanced Materials Published 9 August 2019 Crick labsAndrea SerioFull details Biofunctionalization of TiO2 surfaces with self-assembling layers of oligopeptides covalently grafted to chitosan Authors (8) Valeria Secchi Stefano Franchi Davide Ciccarelli Monica Dettin Annj ZamunerAndrea Serio Giovanna Iucci Chiara Battocchio ACS Biomaterials Science and Engineering Published 13 May 2019 Crick labsAndrea SerioFull details Engineering anisotropic muscle tissue using acoustic cell patterning Authors (21) James PK Armstrong Jennifer L PuetzerAndrea Serio Anne Géraldine Guex Michaella Kapnisi Alexandre Breant[...] Dietmar W Hutmacher Bruce W Drinkwater Travis J Klein Adam W Perriman Molly M Stevens Advanced Materials Published 25 October 2018 Crick labsAndrea SerioFull details Concise review: The cellular conspiracy of Amyotrophic Lateral Sclerosis Authors (2)Andrea SerioRickie Patani Stem Cells Published 1 March 2018 Crick labsAndrea SerioRickie PataniFull details Fabrication of hemin-doped serum albumin-based fibrous scaffolds for neural tissue engineering applications Authors (5) Chia-Chen HsuAndrea Serio Nadav Amdursky Cyril Besnard Molly M Stevens ACS Applied Materials and Interfaces Published 14 February 2018 Crick labsAndrea SerioFull details Correlated heterospectral lipidomics for biomolecular profiling of remyelination in multiple sclerosis Authors (12) Mads S BergholtAndrea Serio James S McKenzie Amanda Boyd Renata F Soares Jocelyn Tillner[...] Vincen Wu Andreas Dannhorn Zoltan Takats Anna Williams Molly M Stevens ACS Central Science Published 24 January 2018 Crick labsAndrea SerioFull details Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS Authors (24) Claire E Hall Zhi YaoMinee ChoiGiulia TyzackAndrea Serio Raphaelle Luisier[...] Christopher R Sibley Andras LakatosJernej UleSonia GandhiRickie Patani Cell Reports Published 30 May 2017 Crick labsJernej UleAndrea SerioRickie PataniNicholas LuscombeSonia GandhiFull details Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2 Authors (19) Karen FS Bell Bashayer Al-Mubarak Marc-André Martel Sean McKay Nicola Wheelan Philip Hasel[...] David JA Wyllie Robert H Scannevin Siddharthan Chandran John D Hayes Giles E Hardingham Nature Communications Published 13 May 2015 Crick labsAndrea SerioFull details Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins Authors (5) Gregor FuhrmannAndrea Serio Manuel Mazo Rekha Nair Molly M Stevens Journal of Controlled Release Published 10 May 2015 Crick labsAndrea SerioFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Biophysical regulations of epigenetic state and notch signaling in neural development using microgroove substrates Authors (7) Chia-Chen HsuAndrea Serio Sahana Gopal Amy Gelmi Ciro Chiappini Ravi A Desai Molly M Stevens ACS Applied Materials and Interfaces Published 13 July 2022 Crick labsAndrea SerioFull details
Bioengineering human skeletal muscle models: Recent advances, current challenges and future perspectives Authors (5) Yunsong Jiang Tugce Torun Sara M MaffiolettiAndrea SerioFrancesco Saverio Tedesco Experimental Cell Research Published 15 July 2022 Crick labsFrancesco Saverio TedescoAndrea SerioFull details
Axonal length determines distinct homeostatic phenotypes in human iPSC derived motor neurons on a bioengineered platform Authors (8)Cathleen Hagemann Carmen Moreno GonzalezLudovica GuettaGiulia Tyzack Ciro Chiappini Andrea LegatiRickie PataniAndrea Serio Advanced Healthcare Materials Published 18 May 2022 Crick labsAndrea SerioRickie PataniFull details
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2 Authors (17) Antonette Bennett Joshua Hull Nelly Jolinon Julie Tordo Katie Moss Enswert Binns[...] Felix Broecker Peter Seeberger Els Henckaerts Robert McKenna Mavis Agbandje-McKenna Journal of Structural Biology Published 1 December 2021 Crick labsAndrea SerioFull details
TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain Authors (4)Jasmine HarleyCathleen HagemannAndrea SerioRickie Patani Brain Communications Published 6 August 2021 Crick labsAndrea SerioRickie PataniFull details
Unsupervised cell segmentation and labelling in neural tissue images Authors (9) S Iglesias-Rey F Antunes-SantosCathleen Hagemann D Gómez-Cabrero H BustinceRickie PataniAndrea Serio B De Baets C Lopez-Molina Applied Sciences (Switzerland) Published 21 April 2021 Crick labsAndrea SerioRickie PataniFull details
Automated and unbiased discrimination of ALS from control tissue at single cell resolution Authors (9)Cathleen HagemannGiulia TyzackDoaa Taha Helen Devine Linda Greensmith Jia NewcombeRickie PataniAndrea Serio Raphaëlle Luisier Brain Pathology Published 1 July 2021 Crick labsAndrea SerioRickie PataniFull details
FUS is lost from nuclei and gained in neurites of motor neurons in a human stem cell model of VCP-related ALS Authors (4)Jasmine HarleyCathleen HagemannAndrea SerioRickie Patani Brain Published 1 December 2020 Crick labsAndrea SerioRickie PataniFull details
An electroactive oligo‐EDOT platform for neural tissue engineering Authors (10) Kaja I Ritzau‐Reid Christopher D Spicer Amy Gelmi Christopher L Grigsby James F Ponder Victoria Bemmer Adam Creamer Ramon VilarAndrea Serio Molly M Stevens Advanced Functional Materials Published 15 October 2020 Crick labsAndrea SerioFull details
Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS Authors (11) Kaitlin Weskamp Elizabeth M Tank Roberto Miguez Jonathon P McBride Nicolás B Gómez Matthew White Ziqiang LinCarmen Moreno GonzalezAndrea Serio Jemeen Sreedharan Sami J Barmada Journal of Clinical Investigation Published 2 March 2020 Crick labsAndrea SerioFull details
Raman spectroscopy: Guiding light for the extracellular matrix Authors (3) Mads S BergholtAndrea Serio Michael B Albro Frontiers in Bioengineering and Biotechnology Published 1 November 2019 Crick labsAndrea SerioFull details
Immunogold FIB-SEM: Combining volumetric ultrastructure visualization with 3D biomolecular analysis to dissect cell-environment interactions Authors (11) Sahana Gopal Ciro Chiappini James PK Armstrong Qu ChenAndrea Serio Chia-Chen Hsu Christoph Meinert Travis J Klein Dietmar W Hutmacher Stephen Rothery Molly M Stevens Advanced Materials Published 9 August 2019 Crick labsAndrea SerioFull details
Biofunctionalization of TiO2 surfaces with self-assembling layers of oligopeptides covalently grafted to chitosan Authors (8) Valeria Secchi Stefano Franchi Davide Ciccarelli Monica Dettin Annj ZamunerAndrea Serio Giovanna Iucci Chiara Battocchio ACS Biomaterials Science and Engineering Published 13 May 2019 Crick labsAndrea SerioFull details
Engineering anisotropic muscle tissue using acoustic cell patterning Authors (21) James PK Armstrong Jennifer L PuetzerAndrea Serio Anne Géraldine Guex Michaella Kapnisi Alexandre Breant[...] Dietmar W Hutmacher Bruce W Drinkwater Travis J Klein Adam W Perriman Molly M Stevens Advanced Materials Published 25 October 2018 Crick labsAndrea SerioFull details
Concise review: The cellular conspiracy of Amyotrophic Lateral Sclerosis Authors (2)Andrea SerioRickie Patani Stem Cells Published 1 March 2018 Crick labsAndrea SerioRickie PataniFull details
Fabrication of hemin-doped serum albumin-based fibrous scaffolds for neural tissue engineering applications Authors (5) Chia-Chen HsuAndrea Serio Nadav Amdursky Cyril Besnard Molly M Stevens ACS Applied Materials and Interfaces Published 14 February 2018 Crick labsAndrea SerioFull details
Correlated heterospectral lipidomics for biomolecular profiling of remyelination in multiple sclerosis Authors (12) Mads S BergholtAndrea Serio James S McKenzie Amanda Boyd Renata F Soares Jocelyn Tillner[...] Vincen Wu Andreas Dannhorn Zoltan Takats Anna Williams Molly M Stevens ACS Central Science Published 24 January 2018 Crick labsAndrea SerioFull details
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS Authors (24) Claire E Hall Zhi YaoMinee ChoiGiulia TyzackAndrea Serio Raphaelle Luisier[...] Christopher R Sibley Andras LakatosJernej UleSonia GandhiRickie Patani Cell Reports Published 30 May 2017 Crick labsJernej UleAndrea SerioRickie PataniNicholas LuscombeSonia GandhiFull details
Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2 Authors (19) Karen FS Bell Bashayer Al-Mubarak Marc-André Martel Sean McKay Nicola Wheelan Philip Hasel[...] David JA Wyllie Robert H Scannevin Siddharthan Chandran John D Hayes Giles E Hardingham Nature Communications Published 13 May 2015 Crick labsAndrea SerioFull details
Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins Authors (5) Gregor FuhrmannAndrea Serio Manuel Mazo Rekha Nair Molly M Stevens Journal of Controlled Release Published 10 May 2015 Crick labsAndrea SerioFull details