Publications

Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation

Authors (8)

Stefania Crotta
Matteo Villa
Jack Major
Katja Finsterbusch
Miriam Llorian
Peter Carmeliet
Joerg Buescher
Andreas Wack

Nature Communications

Published 13 February 2023

Crick labs/ facilities

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Respiratory viruses: New frontiers-a Keystone Symposia report

Authors (27)

Jennifer Cable
Jie Sun
In Su Cheon
Andrew E Vaughan
Italo A Castro
Sydney R Stein
[...]
Ketaki Ganti
Kanta Subbarao
Timothy P Sheahan
Pablo Penaloza-MacMaster
Taylor Eddens

Annals of the New York Academy of Sciences

Published 1 April 2023

Crick labs

Andreas Wack

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Impaired immune response drives age-dependent severity of COVID-19

Authors (20)

Julius Beer
Stefania Crotta
Angele Breithaupt
Annette Ohnemus
Jan Becker
Benedikt Sachs
[...]
Jonas Fuchs
Georg Kochs
Andreas Wack
Martin Schwemmle
Daniel Schnepf

Journal of Experimental Medicine

Published 5 December 2022

Crick labs/ facilities

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Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model

Authors (18)

Peter AC Wing
Maria Prange-Barczynska
Amy Cross
Stefania Crotta
Claudia Orbegozo Rubio
Xiaotong Cheng
[...]
Peter Balfe
Andreas Wack
Tammie Bishop
Francisco J Salguero
Jane A McKeating

PLOS Pathogens

Published 6 September 2022

Crick labs

Andreas Wack

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Anti-type I interferon antibodies as a cause of severe COVID-19

Authors (6)

David C Fajgenbaum
Adrian Hayday
Angela J Rogers
Greg J Towers
Andreas Wack
Ivan Zanoni

Faculty Reviews

Published 10 June 2022

Crick labs

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Host-directed immunotherapy of viral and bacterial infections: past, present and future

Authors (4)

Robert S Wallis
Anne O'Garra
Alan Sher
Andreas Wack

Nature Reviews Immunology

Published 1 February 2023

Crick labs

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Functions of IFNλs in anti-bacterial immunity at mucosal barriers

Authors (4)

Noémie Alphonse
Ruth E Dickenson
Abrar Alrehaili
Charlotte Odendall

Frontiers in Immunology

Published 18 May 2022

Crick labs

Andreas Wack

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A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling

Authors (24)

Noémie Alphonse
Joseph J Wanford
Andrew A Voak
Jack Gay
Shayla Venkhaya
Owen Burroughs
[...]
Martin W Berchtold
Julien RC Bergeron
Andreas Wack
Cammie F Lesser
Charlotte Odendall

Cell

Published 23 June 2022

Crick labs/ facilities

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Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity

Authors (18)

Science Immunology

Published 5 November 2021

Crick labs/ facilities

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Influenza A induces lactate formation to inhibit type I IFN in primary human airway epithelium

Authors (12)

Jacob Thyrsted
Jacob Storgaard
Julia Blay-Cadanet
Alexander Heinz
Anne Laugaard Thielke
Stefania Crotta
[...]
David Olagnier
Andreas Wack
Karsten Hiller
Anne Louise Hansen
Christian Kanstrup Holm

iScience

Published 19 November 2021

Crick labs

Andreas Wack

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A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza

Authors (6)

Journal of Experimental Medicine

Published 1 November 2021

Crick labs/ facilities

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The interferon landscape along the respiratory tract impacts the severity of COVID-19

Authors (28)

Benedetta Sposito
Achille Broggi
Laura Pandolfi
Stefania Crotta
Nicola Clementi
Roberto Ferrarese
[...]
Antonio E Pontiroli
Federica Meloni
Andreas Wack
Nicasio Mancini
Ivan Zanoni

Cell

Published 16 September 2021

Crick labs

Andreas Wack

Full details

Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22

Authors (15)

Daniel Schnepf
Pedro Hernandez
Tanel Mahlakõiv
Stefania Crotta
Meagan E Sullender
Stefan T Peterson
[...]
Celso A Reis
Andreas Diefenbach
Andreas Wack
Megan T Baldridge
Peter Staeheli

PLOS ONE

Published 12 August 2021

Crick labs

Andreas Wack

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Selective Janus kinase inhibition preserves interferon-λ-mediated antiviral responses

Authors (17)

Daniel Schnepf
Stefania Crotta
Thiprampai Thamamongood
Megan Stanifer
Laura Polcik
Annette Ohnemus
[...]
Susanne Kirschnek
Steeve Boulant
Martin Schwemmle
Andreas Wack
Peter Staeheli

Science Immunology

Published 14 May 2021

Crick labs/ facilities

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Monocyte and dendritic cell defects in COVID-19

Authors (1)

Andreas Wack

Nature Cell Biology

Published 1 May 2021

Crick labs

Andreas Wack

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Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival

Authors (8)

Journal of Experimental Medicine

Published 1 February 2021

Crick labs/ facilities

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Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option

Authors (9)

Nature Genetics

Published 1 December 2020

Crick labs/ facilities

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An ace model for SARS-CoV-2 infection

Authors (2)

Journal of Experimental Medicine

Published 7 December 2020

Crick labs

Andreas Wack

Full details

Teaching old dogs new tricks? The plasticity of lung alveolar macrophage subsets

Authors (2)

Trends in Immunology

Published 1 October 2020

Crick labs

Andreas Wack

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Publications

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Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation

Respiratory viruses: New frontiers-a Keystone Symposia report

Impaired immune response drives age-dependent severity of COVID-19

Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model

SARS-CoV-2 S2-targeted vaccination elicits broadly neutralizing antibodies

Anti-type I interferon antibodies as a cause of severe COVID-19

Host-directed immunotherapy of viral and bacterial infections: past, present and future

Functions of IFNλs in anti-bacterial immunity at mucosal barriers

A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling

Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity

Influenza A induces lactate formation to inhibit type I IFN in primary human airway epithelium

A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza

The interferon landscape along the respiratory tract impacts the severity of COVID-19

Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22

Selective Janus kinase inhibition preserves interferon-λ-mediated antiviral responses

Monocyte and dendritic cell defects in COVID-19

Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival

Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option

An ace model for SARS-CoV-2 infection

Teaching old dogs new tricks? The plasticity of lung alveolar macrophage subsets

The Francis Crick Institute is a unique partnership between

Research case studies

Vacancies

Cut + Paste exhibition

Coronavirus (COVID-19) research

About us

Lab content

Publications

Year published

Research topics

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Publication type

Journal

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