de Strooper & Arancibia lab
Cellular Phase of Alzheimer’s Disease Laboratory
: Publications

Publications

Displaying 1 - 20 of 145

Last updated : 30 November 2023 02:38

The γ-secretase substrate proteome and its role in cell signaling regulation

Authors (14)

Pengfei Hou
Magdalena Zielonka
Lutgarde Serneels
Anna Martinez-Muriana
Nicola Fattorelli
Leen Wolfs
[...]
Tom Theys
Mark Fiers
Renzo Mancuso
Andrew JM Howden
Bart De Strooper

Molecular Cell

Published 16 November 2023

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Bart de Strooper | Lorena Arancibia

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MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease

Authors (18)

Sriram Balusu
Katrien Horré
Nicola Thrupp
Katleen Craessaerts
An Snellinx
Lutgarde Serneels
[...]
Wei-Ting Chen
Dietmar Rudolf Thal
Evgenia Salta
Mark Fiers
Bart De Strooper

Science

Published 15 September 2023

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Bart de Strooper | Lorena Arancibia

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Intracerebral hemorrhage among blood donors and their transfusion recipients

Authors (11)

Jingcheng Zhao
Klaus Rostgaard
Elsa Lauwers
Torsten Dahlén
Sisse Rye Ostrowski
Christian Erikstrup
Ole Birger Pedersen
Bart De Strooper
Robin Lemmens
Henrik Hjalgrim
Gustaf Edgren

JAMA

Published 12 September 2023

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Bart de Strooper | Lorena Arancibia

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Discovery of brain permeable 2-Azabicyclo[2.2.2]octane sulfonamides as a novel class of presenilin-1 selective γ-secretase inhibitors

Authors (6)

Rajeshwar Narlawar
Lutgarde Serneels
Celia Gaffric
Harrie JM Gijsen
Bart De Strooper
François Bischoff

European Journal of Medicinal Chemistry

Published 15 November 2023

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Bart de Strooper | Lorena Arancibia

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A fully automated home cage for long-term continuous phenotyping of mouse cognition and behavior

Authors (8)

H Ho
N Kejzar
H Sasaguri
T Saito
TC Saido
Bart De Strooper
M Bauza
J Krupic

Cell Reports Methods

Published 24 July 2023

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Bart de Strooper | Lorena Arancibia

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Novel human/non-human primate cross-reactive anti-transferrin receptor nanobodies for brain delivery of biologics

Authors (7)

Laura Rué
Tom Jaspers
Isabelle MS Degors
Sam Noppen
Dominique Schols
Bart De Strooper
Maarten Dewilde

Pharmaceutics

Published 16 June 2023

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Bart de Strooper | Lorena Arancibia

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Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease

Authors (28)

Sara Calafate
Gökhan Özturan
Nicola Thrupp
Jeroen Vanderlinden
Luísa Santa-Marinha
Rafaela Morais-Ribeiro
[...]
Tiago Gil Oliveira
Inna Slutsky
Antoine Adamantidis
Bart De Strooper
Joris de Wit

Nature Neuroscience

Published 1 June 2023

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Bart de Strooper | Lorena Arancibia

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Selective inhibitors of the PSEN1-gamma-secretase complex

Authors (13)

Lutgarde Serneels
Rajeshwar Narlawar
Laura Perez Benito
Marti Municoy
Victor Guallar
Dries T’Syen
[...]
Erwin Fraiponts
Gary Tresadern
Peter WM Roevens
Harrie JM Gijsen
Bart De Strooper

Journal of Biological Chemistry

Published 1 June 2023

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Bart de Strooper | Lorena Arancibia

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microRNA-132 regulates gene expression programs involved in microglial homeostasis

Authors (18)

H Walgrave
A Penning
G Tosoni
S Snoeck
K Davie
E Davis
[...]
R Mancuso
M Fiers
AJM Howden
Bart De Strooper
E Salta

iScience

Published 16 June 2023

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Bart de Strooper | Lorena Arancibia

Full details

Apoptotic cell death in disease-Current understanding of the NCCD 2023

Authors (228)

Ilio Vitale
Federico Pietrocola
Emma Guilbaud
Stuart A Aaronson
John M Abrams
Dieter Adam
[...]
Boris Zhivotovsky
Wenzhao Zhou
Mauro Piacentini
Guido Kroemer
Lorenzo Galluzzi

Cell Death and Differentiation

Published 1 May 2023

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Neurodegeneration cell per cell

Authors (5)

Sriram Balusu
Roman Praschberger
Elsa Lauwers
Bart De Strooper
Patrik Verstreken

Neuron

Published 15 March 2023

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Bart de Strooper | Lorena Arancibia

Full details

Microglial expression of the Wnt signaling modulator DKK2 differs between human Alzheimer’s disease brains and mouse neurodegeneration models

Authors (9)

Nozie D Aghaizu
Sarah Jolly
Satinder K Samra
Bernadett Kalmar
Katleen Craessaerts
Linda Greensmith
Patricia C Salinas
Bart De Strooper
Paul J Whiting

eNeuro

Published 4 January 2023

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Bart de Strooper | Lorena Arancibia

Full details

Astrocytes mediate neuronal network hyperactivity in early AD

Authors (22)

D Shah
W Gsell
J Wahis
ES Luckett
T Jamoulle
P Preman
[...]
R D'Hooge
R Vandenberghe
U Himmelreich
V Bonin
Bart De Strooper

Alzheimer's and Dementia

Published 1 December 2022

Crick labs

Bart de Strooper | Lorena Arancibia

Full details

Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons

Authors (9)

Sebastiaan Moonen
Marta J Koper
Evelien Van Schoor
Jolien M Schaeverbeke
Rik Vandenberghe
Christine AF von Arnim
Thomas Tousseyn
Bart De Strooper
Dietmar Rudolf Thal

Acta Neuropathologica

Published 1 February 2023

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Bart de Strooper | Lorena Arancibia

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Microglia states and nomenclature: A field at its crossroads

Authors (96)

Rosa C Paolicelli
Amanda Sierra
Beth Stevens
Marie-Eve Tremblay
Adriano Aguzzi
Bahareh Ajami
[...]
Hiroaki Wake
Valérie Wittamer
Susanne A Wolf
Long-Jun Wu
Tony Wyss-Coray

Neuron

Published 2 November 2022

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Bart de Strooper | Lorena Arancibia

Full details

Diabetes and Alzheimer's disease: shared genetic susceptibility?

Authors (3)

John Hardy
Bart De Strooper
Valentina Escott-Price

The Lancet Neurology

Published 1 November 2022

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Bart de Strooper | Lorena Arancibia

Full details

VHHs as tools for therapeutic protein delivery to the central nervous system

Authors (6)

Yessica Wouters
Tom Jaspers
Laura Rué
Lutgarde Serneels
Bart De Strooper
Maarten Dewilde

Fluids and Barriers of the CNS

Published 3 October 2022

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Bart de Strooper | Lorena Arancibia

Full details

LATE-NC aggravates GVD-mediated necroptosis in Alzheimer’s disease

Authors (15)

Marta J Koper
Sandra O Tomé
Klara Gawor
Annelies Belet
Evelien Van Schoor
Jolien Schaeverbeke
[...]
Christine AF von Arnim
Sriram Balusu
Matthew B Blaschko
Bart De Strooper
Dietmar Rudolf Thal

Acta Neuropathologica Communications

Published 3 September 2022

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Bart de Strooper | Lorena Arancibia

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Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer’s disease

Authors (22)

Disha Shah
Willy Gsell
Jérôme Wahis
Emma S Luckett
Tarik Jamoulle
Ben Vermaercke
[...]
Rudi D’Hooge
Rik Vandenberghe
Uwe Himmelreich
Vincent Bonin
Bart De Strooper

Cell Reports

Published 23 August 2022

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Bart de Strooper | Lorena Arancibia

Full details

CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity

Authors (30)

Wenting Guo
Haibo Wang
Arun Kumar Tharkeshwar
Julien Couthouis
Elke Braems
Pegah Masrori
[...]
Bart De Strooper
Dirk Daelemans
Philip Van Damme
Ludo Van Den Bosch
Catherine Verfaillie

Alzheimer's & Dementia

Published 1 April 2023

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Bart de Strooper | Lorena Arancibia

Full details

Research case studies

Doctoral clinical fellows

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About us

de Strooper & Arancibia lab
Cellular Phase of Alzheimer’s Disease Laboratory
: Publications

Lab content

Publications

The γ-secretase substrate proteome and its role in cell signaling regulation

MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease

Intracerebral hemorrhage among blood donors and their transfusion recipients

Discovery of brain permeable 2-Azabicyclo[2.2.2]octane sulfonamides as a novel class of presenilin-1 selective γ-secretase inhibitors

A fully automated home cage for long-term continuous phenotyping of mouse cognition and behavior

Novel human/non-human primate cross-reactive anti-transferrin receptor nanobodies for brain delivery of biologics

Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease

Selective inhibitors of the PSEN1-gamma-secretase complex

microRNA-132 regulates gene expression programs involved in microglial homeostasis

Apoptotic cell death in disease-Current understanding of the NCCD 2023

Neurodegeneration cell per cell

Microglial expression of the Wnt signaling modulator DKK2 differs between human Alzheimer’s disease brains and mouse neurodegeneration models

Astrocytes mediate neuronal network hyperactivity in early AD

Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons

Microglia states and nomenclature: A field at its crossroads

Diabetes and Alzheimer's disease: shared genetic susceptibility?

VHHs as tools for therapeutic protein delivery to the central nervous system

LATE-NC aggravates GVD-mediated necroptosis in Alzheimer’s disease

Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer’s disease

CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity

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About us

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Publications

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