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Breadcrumb Bart de Strooper | Lorena Arancibia de Strooper & Arancibia lab Cellular Phase of Alzheimer’s Disease Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Publications Lab members Publications Displaying 21 - 40 of 148Last updated : 28 March 2024 03:54 Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer’s disease Authors (22) Disha Shah Willy Gsell Jérôme Wahis Emma S Luckett Tarik Jamoulle Ben Vermaercke[...] Rudi D’Hooge Rik Vandenberghe Uwe Himmelreich Vincent BoninBart De Strooper Cell Reports Published 23 August 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity Authors (30) Wenting Guo Haibo Wang Arun Kumar Tharkeshwar Julien Couthouis Elke Braems Pegah Masrori[...]Bart De Strooper Dirk Daelemans Philip Van Damme Ludo Van Den Bosch Catherine Verfaillie Alzheimer's & Dementia Published 1 April 2023 Crick labsBart de Strooper | Lorena ArancibiaFull details Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation Authors (42) Lidia Yshii Emanuela Pasciuto Pascal Bielefeld Loriana Mascali Pierre Lemaitre Marika Marino[...] Ludo Van Den Bosch Uwe Himmelreich Carlos P Fitzsimons Matthew G Holt Adrian Liston Nature Immunology Published 1 June 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer’s disease Authors (14) Joshua Stevenson-Hoare Amanda Heslegrave Ganna Leonenko Dina Fathalla Eftychia Bellou Lauren Luckcuck[...] John HardyBart De Strooper Julie Williams Henrik Zetterberg Valentina Escott-Price Brain Published 1 February 2023 Crick labsBart de Strooper | Lorena ArancibiaFull details AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model Authors (23) Marika Marino Lujia Zhou Melvin Y Rincon Zsuzsanna Callaerts‐Vegh Jens Verhaert Jérôme Wahis[...] Takaomi C Saido Serge Muyldermans Adrian ListonBart De Strooper Matthew G Holt EMBO Molecular Medicine Published 7 April 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details Editorial overview: Neurobiology of disease Authors (2)Bart De Strooper Huda Zoghbi Current Opinion in Neurobiology Published 1 February 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details Do we still need animals? Surveying the role of animal‐free models in Alzheimer’s and Parkinson’s disease research Authors (8) Liesbeth Aerts Beatrice Miccoli Aaron Delahanty Hilda Witters Sandra VerstraelenBart De Strooper Dries Braeken Patrik Verstreken The EMBO Journal Published 15 March 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics Authors (2) Eric KarranBart De Strooper Nature Reviews Drug Discovery Published 1 April 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details The promise of microRNA-based therapies in Alzheimer’s disease: challenges and perspectives Authors (4) Hannah Walgrave Lujia ZhouBart De Strooper Evgenia Salta Molecular Neurodegeneration Published 6 November 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details Astrocyte Ca2+-evoked ATP release regulates myelinated axon excitability and conduction speed Authors (6) Jonathan LezmyLorena Arancibia Carcamo Tania Quintela-López Diane L Sherman Peter J Brophy David Attwell Science Published 15 October 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details Bart De Strooper Authors (1)Bart De Strooper Neuron Published 6 October 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques Authors (11) Pranav Preman Julia TCW Sara Calafate An Snellinx Maria Alfonso-Triguero Nikky Corthout Sebastian Munck Dietmar Rudolf Thal Alison M GoateBart De Strooper Amaia M Arranz Molecular Neurodegeneration Published 25 September 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details The case for low-level BACE1 inhibition for the prevention of Alzheimer disease Authors (14) Eric McDade Iryna Voytyuk Paul Aisen Randall J Bateman Maria C CarrilloBart De Strooper[...] Pierre N Tariot Riqiang Yan Colin L Masters Robert Vassar Stefan F Lichtenthaler Nature Reviews Neurology Published 1 November 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details The amyloid precursor protein is a conserved Wnt receptor Authors (12) Tengyuan Liu Tingting Zhang Maya Nicolas Lydie Boussicault Heather Rice Alessia Soldano[...] Iveta Petrova Lee FradkinBart De Strooper Marie-Claude Potier Bassem A Hassan eLife Published 9 September 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details The Dementia UK Ecosystem: a call to action Authors (4) G Lalli M Rossor JB RoweBart De Strooper The Lancet Neurology Published 1 September 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details Cellular senescence at the crossroads of inflammation and Alzheimer's disease Authors (3)Ana GuerreroLopezBart De StrooperLorena Arancibia Carcamo Trends in Neurosciences Published 5 August 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details Aducanumab: a new phase in therapeutic development for Alzheimer’s disease? Authors (4) Giovanna Lalli Jonathan M Schott John HardyBart De Strooper EMBO Molecular Medicine Published 9 August 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores Authors (8) Ganna Leonenko Emily Baker Joshua Stevenson-Hoare Annerieke Sierksma Mark Fiers Julie WilliamsBart De Strooper Valentina Escott-Price Nature Communications Published 23 July 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details From junk to function: LncRNAs in CNS health and disease Authors (4) Rafaela Policarpo Annerieke SierksmaBart De Strooper Constantin d’Ydewalle Frontiers in Molecular Neuroscience Published 1 July 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia Authors (20) Diana P Benitez Shenyi Jiang Jack Wood Rui Wang Chloe M Hall Carlijn Peerboom[...]Bart De Strooper Dervis A Salih Takshashila Tripathi Frances A Edwards Damian M Cummings Molecular Neurodegeneration Published 15 July 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details Pagination First page First Previous page Previous Page 1 Current page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer’s disease Authors (22) Disha Shah Willy Gsell Jérôme Wahis Emma S Luckett Tarik Jamoulle Ben Vermaercke[...] Rudi D’Hooge Rik Vandenberghe Uwe Himmelreich Vincent BoninBart De Strooper Cell Reports Published 23 August 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details
CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity Authors (30) Wenting Guo Haibo Wang Arun Kumar Tharkeshwar Julien Couthouis Elke Braems Pegah Masrori[...]Bart De Strooper Dirk Daelemans Philip Van Damme Ludo Van Den Bosch Catherine Verfaillie Alzheimer's & Dementia Published 1 April 2023 Crick labsBart de Strooper | Lorena ArancibiaFull details
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation Authors (42) Lidia Yshii Emanuela Pasciuto Pascal Bielefeld Loriana Mascali Pierre Lemaitre Marika Marino[...] Ludo Van Den Bosch Uwe Himmelreich Carlos P Fitzsimons Matthew G Holt Adrian Liston Nature Immunology Published 1 June 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details
Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer’s disease Authors (14) Joshua Stevenson-Hoare Amanda Heslegrave Ganna Leonenko Dina Fathalla Eftychia Bellou Lauren Luckcuck[...] John HardyBart De Strooper Julie Williams Henrik Zetterberg Valentina Escott-Price Brain Published 1 February 2023 Crick labsBart de Strooper | Lorena ArancibiaFull details
AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model Authors (23) Marika Marino Lujia Zhou Melvin Y Rincon Zsuzsanna Callaerts‐Vegh Jens Verhaert Jérôme Wahis[...] Takaomi C Saido Serge Muyldermans Adrian ListonBart De Strooper Matthew G Holt EMBO Molecular Medicine Published 7 April 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details
Editorial overview: Neurobiology of disease Authors (2)Bart De Strooper Huda Zoghbi Current Opinion in Neurobiology Published 1 February 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details
Do we still need animals? Surveying the role of animal‐free models in Alzheimer’s and Parkinson’s disease research Authors (8) Liesbeth Aerts Beatrice Miccoli Aaron Delahanty Hilda Witters Sandra VerstraelenBart De Strooper Dries Braeken Patrik Verstreken The EMBO Journal Published 15 March 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details
The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics Authors (2) Eric KarranBart De Strooper Nature Reviews Drug Discovery Published 1 April 2022 Crick labsBart de Strooper | Lorena ArancibiaFull details
The promise of microRNA-based therapies in Alzheimer’s disease: challenges and perspectives Authors (4) Hannah Walgrave Lujia ZhouBart De Strooper Evgenia Salta Molecular Neurodegeneration Published 6 November 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
Astrocyte Ca2+-evoked ATP release regulates myelinated axon excitability and conduction speed Authors (6) Jonathan LezmyLorena Arancibia Carcamo Tania Quintela-López Diane L Sherman Peter J Brophy David Attwell Science Published 15 October 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
Bart De Strooper Authors (1)Bart De Strooper Neuron Published 6 October 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques Authors (11) Pranav Preman Julia TCW Sara Calafate An Snellinx Maria Alfonso-Triguero Nikky Corthout Sebastian Munck Dietmar Rudolf Thal Alison M GoateBart De Strooper Amaia M Arranz Molecular Neurodegeneration Published 25 September 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
The case for low-level BACE1 inhibition for the prevention of Alzheimer disease Authors (14) Eric McDade Iryna Voytyuk Paul Aisen Randall J Bateman Maria C CarrilloBart De Strooper[...] Pierre N Tariot Riqiang Yan Colin L Masters Robert Vassar Stefan F Lichtenthaler Nature Reviews Neurology Published 1 November 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
The amyloid precursor protein is a conserved Wnt receptor Authors (12) Tengyuan Liu Tingting Zhang Maya Nicolas Lydie Boussicault Heather Rice Alessia Soldano[...] Iveta Petrova Lee FradkinBart De Strooper Marie-Claude Potier Bassem A Hassan eLife Published 9 September 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
The Dementia UK Ecosystem: a call to action Authors (4) G Lalli M Rossor JB RoweBart De Strooper The Lancet Neurology Published 1 September 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
Cellular senescence at the crossroads of inflammation and Alzheimer's disease Authors (3)Ana GuerreroLopezBart De StrooperLorena Arancibia Carcamo Trends in Neurosciences Published 5 August 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
Aducanumab: a new phase in therapeutic development for Alzheimer’s disease? Authors (4) Giovanna Lalli Jonathan M Schott John HardyBart De Strooper EMBO Molecular Medicine Published 9 August 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores Authors (8) Ganna Leonenko Emily Baker Joshua Stevenson-Hoare Annerieke Sierksma Mark Fiers Julie WilliamsBart De Strooper Valentina Escott-Price Nature Communications Published 23 July 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
From junk to function: LncRNAs in CNS health and disease Authors (4) Rafaela Policarpo Annerieke SierksmaBart De Strooper Constantin d’Ydewalle Frontiers in Molecular Neuroscience Published 1 July 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details
Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia Authors (20) Diana P Benitez Shenyi Jiang Jack Wood Rui Wang Chloe M Hall Carlijn Peerboom[...]Bart De Strooper Dervis A Salih Takshashila Tripathi Frances A Edwards Damian M Cummings Molecular Neurodegeneration Published 15 July 2021 Crick labsBart de Strooper | Lorena ArancibiaFull details