de Strooper & Arancibia lab
Cellular Phase of Alzheimer’s Disease Laboratory
: Publications

Publications

Displaying 61 - 80 of 150

Last updated : 20 April 2024 02:34

Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils

Authors (15)

Linda Cerofolini
Enrico Ravera
Sara Bologna
Thomas Wiglenda
Annett Böddrich
Bettina Purfürst
[...]
Leonardo Gonnelli
Marco Fragai
Bart De Strooper
Erich E Wanker
Claudio Luchinat

Chemical Communications

Published 11 August 2020

Crick labs

Bart de Strooper | Lorena Arancibia

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Tipping the scales: Peptide-dependent dysregulation of neural circuit dynamics in Alzheimer's disease

Authors (4)

Samuel S Harris
Fred Wolf
Bart De Strooper
Marc Aurel Busche

Neuron

Published 5 August 2020

Crick labs

Bart de Strooper | Lorena Arancibia

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CHCHD2 harboring Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2

Authors (8)

Tom Cornelissen
Marco Spinazzi
Shaun Martin
Dorien Imberechts
Peter Vangheluwe
Matthew Bird
Bart De Strooper
Wim Vandenberghe

Human Molecular Genetics

Published 1 April 2020

Crick labs

Bart de Strooper | Lorena Arancibia

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The β-secretase BACE1 in Alzheimer's disease

Authors (26)

H Hampel
R Vassar
Bart De Strooper
J Hardy
M Willem
N Singh
[...]
T Kimura
L Yarenis
S Lista
L Kramer
A Vergallo

Biological Psychiatry

Published 15 April 2021

Crick labs

Bart de Strooper | Lorena Arancibia

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Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology

Authors (11)

Annerieke Sierksma
Ashley Lu
Renzo Mancuso
Nicola Fattorelli
Nicola Thrupp
Evgenia Salta
Jesus Zoco
David Blum
Luc Buée
Bart De Strooper
Mark Fiers

EMBO Molecular Medicine

Published 6 March 2020

Crick labs

Bart de Strooper | Lorena Arancibia

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Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

Authors (11)

Heather C Rice
Gabriele Marcassa
Iordana Chrysidou
Katrien Horré
Tracy L Young-Pearse
Ulrike C Müller
Takashi Saito
Takaomi C Saido
Robert Vassar
Joris de Wit
Bart De Strooper

Molecular Neurodegeneration

Published 8 January 2020

Crick labs

Bart de Strooper | Lorena Arancibia

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Axonal odorant receptors mediate axon targeting

Authors (13)

Ilaria Zamparo
Simona Francia
Sira Angela Franchi
Nelly Redolfi
Elisa Costanzi
Axelle Kerstens
[...]
Patrizia Polverino de Laureto
Sebastian Munck
Bart De Strooper
Hiroaki Matsunami
Claudia Lodovichi

Cell Reports

Published 24 December 2019

Crick labs

Bart de Strooper | Lorena Arancibia

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EphA4 loss improves social memory performance and alters dendritic spine morphology without changes in amyloid pathology in a mouse model of Alzheimer's disease

Authors (15)

Lindsay Poppe
Laura Rué
Mieke Timmers
Annette Lenaerts
Annet Storm
Zsuzsanna Callaerts-Vegh
[...]
Ludo Van Den Bosch
Rudi D'Hooge
Bart De Strooper
Wim Robberecht
Robin Lemmens

Alzheimer's Research and Therapy

Published 12 December 2019

Crick labs

Bart de Strooper | Lorena Arancibia

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Necrosome complex detected in granulovacuolar degeneration is associated with neuronal loss in Alzheimer's disease

Authors (10)

Marta J Koper
Evelien Van Schoor
Simona Ospitalieri
Rik Vandenberghe
Mathieu Vandenbulcke
Christine AF von Arnim
Thomas Tousseyn
Sriram Balusu
Bart De Strooper
Dietmar Rudolf Thal

Acta Neuropathologica

Published 1 March 2020

Crick labs

Bart de Strooper | Lorena Arancibia

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Stem-cell-derived human microglia transplanted in mouse brain to study human disease

Authors (19)

Renzo Mancuso
Johanna Van Den Daele
Nicola Fattorelli
Leen Wolfs
Sriram Balusu
Oliver Burton
[...]
Tom Theys
V Hugh Perry
Catherine Verfaillie
Mark Fiers
Bart De Strooper

Nature Neuroscience

Published 1 December 2019

Crick labs

Bart de Strooper | Lorena Arancibia

Full details

Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery

Authors (10)

Souvik Modi
Guillermo López-Doménech
Elise F Halff
Christian Covill-Cooke
Davor Ivankovic
Daniela Melandri
Lorena Arancibia Carcamo
Jemima J Burden
Alan R Lowe
Josef T Kittler

Nature Communications

Published 27 September 2019

Crick labs

Bart de Strooper | Lorena Arancibia

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P2Y13 receptors regulate microglial morphology, surveillance, and resting levels of interleukin 1β release

Authors (9)

Vasiliki Kyrargyri
Christian Madry
Ali Rifat
Lorena Arancibia Carcamo
Steffan P Jones
Victor TT Chan
Yajing Xu
Bernard Robaye
David Attwell

Glia

Published 1 February 2020

Crick labs

Bart de Strooper | Lorena Arancibia

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Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition

Authors (13)

Roger A Habets
Charles E de Bock
Lutgarde Serneels
Inge Lodewijckx
Delphine Verbeke
David Nittner
[...]
James Dooley
Adrian Liston
Tom Taghon
Jan Cools
Bart De Strooper

Science Translational Medicine

Published 29 May 2019

Crick labs

Bart de Strooper | Lorena Arancibia

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The major risk factors for Alzheimer's disease: Age, sex, and genes modulate the microglia response to Aβ plaques

Authors (19)

Carlo Sala Frigerio
Leen Wolfs
Nicola Fattorelli
Nicola Thrupp
Iryna Voytyuk
Inga Schmidt
[...]
Eric Karran
Bradley Hyman
V Hugh Perry
Mark Fiers
Bart De Strooper

Cell Reports

Published 23 April 2019

Crick labs

Bart de Strooper | Lorena Arancibia

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The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications

Authors (2)

Amaia M Arranz
Bart De Strooper

Lancet Neurology

Published 1 April 2019

Crick labs

Bart de Strooper | Lorena Arancibia

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Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation

Authors (19)

Sonja M Sachse
Sam Lievens
Luís F Ribeiro
Dan Dascenco
Delphine Masschaele
Katrien Horré
[...]
Stéphane Plaisance
Jan Tavernier
Bart De Strooper
Joris De Wit
Dietmar Schmucker

The EMBO Journal

Published 15 March 2019

Crick labs

Bart de Strooper | Lorena Arancibia

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Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission

Authors (19)

Heather C Rice
Daniel de Malmazet
An Schreurs
Samuel Frere
Inge Van Molle
Alexander N Volkov
[...]
Keimpe D Wierda
Inna Slutsky
Karl Farrow
Bart De Strooper
Joris de Wit

Science

Published 11 January 2019

Crick labs

Bart de Strooper | Lorena Arancibia

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PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome

Authors (13)

Marco Spinazzi
Enrico Radaelli
Katrien Horré
Amaia M Arranz
Natalia V Gounko
Patrizia Agostinis
[...]
Vanessa Alexandra Morais
Guillermo Lopez-Lluch
Lutgarde Serneels
Placido Navas
Bart De Strooper

Proceedings of the National Academy of Sciences of USA

Published 2 January 2019

Crick labs

Bart de Strooper | Lorena Arancibia

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Diabetes and Alzheimer's disease: A link not as simple as it seems

Authors (2)

Isabel H Salas
Bart De Strooper

Neurochemical Research

Published 15 June 2019

Crick labs

Bart de Strooper | Lorena Arancibia

Full details

Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2

Authors (13)

Christel Claes
Johanna Van Den Daele
Ruben Boon
Sarah Schouteden
Alessio Colombo
Laura Sebastian Monasor
[...]
FatemehArefeh Nami
Bernd Bohrmann
Sabina Tahirovic
Bart De Strooper
Catherine M Verfaillie

Alzheimer's and Dementia

Published 1 March 2019

Crick labs

Bart de Strooper | Lorena Arancibia

Full details

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Hello Brain!

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de Strooper & Arancibia lab
Cellular Phase of Alzheimer’s Disease Laboratory
: Publications

Lab content

Publications

Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils

Tipping the scales: Peptide-dependent dysregulation of neural circuit dynamics in Alzheimer's disease

CHCHD2 harboring Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2

The β-secretase BACE1 in Alzheimer's disease

Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology

Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

Axonal odorant receptors mediate axon targeting

EphA4 loss improves social memory performance and alters dendritic spine morphology without changes in amyloid pathology in a mouse model of Alzheimer's disease

Necrosome complex detected in granulovacuolar degeneration is associated with neuronal loss in Alzheimer's disease

Stem-cell-derived human microglia transplanted in mouse brain to study human disease

Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery

P2Y13 receptors regulate microglial morphology, surveillance, and resting levels of interleukin 1β release

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition

The major risk factors for Alzheimer's disease: Age, sex, and genes modulate the microglia response to Aβ plaques

The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications

Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation

Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission

PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome

Diabetes and Alzheimer's disease: A link not as simple as it seems

Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2

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Postdoctoral clinical fellows

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About us

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Publications

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