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Breadcrumb Ben Schumann Schumann lab Chemical Glycobiology Laboratory : Publications Lab contentLab contentIn this section Overview News Publications Vacancies Members Synthetic sugars (photo) help to understand how glycans modify essential biological processes. Toggle to view hero caption PublicationsYear published2024 (1)2023 (6)2022 (1)2021 (3)2020 (4) Facet Year publishedResearch topicsBiochemistry & Proteomics (15)Cell Biology (15)Chemical Biology & High Throughput (15)Metabolism (15)Synthetic Biology (15)Tumour Biology (15)Structural Biology & Biophysics (9)Computational & Systems Biology (6)Genetics & Genomics (4)Infectious Disease (4)Genome Integrity & Repair (2)Human Biology & Physiology (2)Model Organisms (2)Signalling & Oncogenes (2)Stem Cells (2)Cell Cycle & Chromosomes (1)Developmental Biology (1)Gene Expression (1)Immunology (1)Neurosciences (1) Facet Research topicsCrick/Pre-Crick (-)Crick publications (15) Facet Crick/Pre-CrickPublication typeJournal article (15)Primary research (9)Review (2)Biography (1)Commentary (1)Editorial (1)Method (1) Facet Publication typeJournalACS Chemical Biology (2)Nature Communications (2)ACS Central Science (1)Cell Chemical Biology (1)Communications Chemistry (1)Current Opinion in Chemical Biology (1)Israel Journal of Chemistry (1)Journal of Cell Science (1)Journal of the American Society for Mass Spectrometry (1)Molecular Cell (1)Oncogene (1)Proceedings of the National Academy of Sciences of USA (1)STAR Protocols (1) Facet Journal Publications Displaying 1 - 15 of 15Last updated : 20 April 2024 03:45 Voices: Challenges and opportunities for bioorthogonal chemistry Authors (5) KL HsuBen Schumann E Sletten E Vinogradova P Zou Cell Chemical Biology Published 21 March 2024 Crick labsBen SchumannFull details Cell scientist to watch – Ben Schumann Authors (2) Amelia GlazierBen Schumann Journal of Cell Science Published 1 November 2023 Crick labsBen SchumannFull details Molecular mechanism of decision-making in glycosaminoglycan biosynthesis Authors (8) Douglas Sammon Anja Krueger Marta Busse-Wicher Rhodri Marc Morgan Stuart M HaslamBen SchumannDavid Briggs Erhard Hohenester Nature Communications Published 13 October 2023 Crick labs/ facilitiesBen SchumannNeil McDonaldChemical BiologyFull details O-linked sialoglycans modulate the proteolysis of SARS-CoV-2 spike and likely contribute to the mutational trajectory in variants of concern Authors (22)Edgar Gonzalez-RodriguezMia Zol-HanlonGanka Bineva-ToddAndrea MarchesiMark Skehel Keira E Mahoney[...]Robert Wilkinson Emma C Wall Ramón Hurtado-Guerrero Stacy A MalakerBen Schumann ACS Central Science Published 22 March 2023 Crick labs/ facilitiesRobert J WilkinsonBen SchumannSteve GamblinStructural BiologyProteomicsChemical BiologyFull details Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth Authors (59) Emma Scott Kirsty HodgsonBea Calle Helen Turner Kathleen Cheung Abel Bermudez[...] Sharon Pitteri Ning Wang David J ElliottBen Schumann Jennifer Munkley Oncogene Published 16 March 2023 Crick labs/ facilitiesBen SchumannStructural BiologyFull details Celebrating the contributions of Carolyn Bertozzi to bioorthogonal chemistry and its application to glycoscience Authors (3) Jessica R Kramer Matthew R PrattBen Schumann Israel Journal of Chemistry Published 1 February 2023 Crick labsBen SchumannFull details Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells Authors (10)Bea CalleEdgar Gonzalez-Rodriguez Keira E MahoneyAnna CioceGanka Bineva-ToddOmur Yilmaz TastanChloe Roustan Helen Flynn Stacy A MalakerBen Schumann STAR Protocols Published 17 March 2023 Crick labs/ facilitiesBen SchumannStructural BiologyProteomicsFull details Cell-specific bioorthogonal tagging of glycoproteins Authors (31)Anna CioceBea CalleTatiana Rizou Sarah C LoweryVicky Bridgeman Keira E Mahoney[...] Stuart M Haslam Sabine L Flitsch Stacy A MalakerIlaria MalanchiBen Schumann Nature Communications Published 25 October 2022 Crick labs/ facilitiesJernej UleBen SchumannIlaria MalanchiLuiz Pedro CarvalhoStructural BiologyProteomicsBioinformatics and BiostatisticsLight MicroscopyCell ServicesBiological Research FacilityAdvanced SequencingFull details 4-deoxy-4-fluoro-GalNAz (4FGalNAz) is a metabolic chemical reporter of O-GlcNAc modifications, highlighting the notable substrate flexibility of O-GlcNAc transferase Authors (15) Emma G Jackson Giuliano Cutolo Bo Yang Nageswari Yarravarapu Mary WN BurnsGanka Bineva-Todd[...] Hazel M HoldenBen Schumann Jennifer J Kohler Christina M Woo Matthew R Pratt ACS Chemical Biology Published 21 January 2022 Crick labs/ facilitiesBen SchumannStructural BiologyFull details Benefits of chemical sugar modifications introduced by click chemistry for glycoproteomic analyses Authors (11)Bea CalleGanka Bineva-ToddAndrea Marchesi Helen Flynn Mattia GhirardelloOmur Yilmaz TastanChloe Roustan Junwon Choi M Carmen GalanBen Schumann Stacy A Malaker Journal of the American Society for Mass Spectrometry Published 1 September 2021 Crick labs/ facilitiesBen SchumannStructural BiologyProteomicsMetabolomicsFull details Optimization of metabolic oligosaccharide engineering with Ac4GalNAlk and Ac4GlcNAlk by an engineered pyrophosphorylase Authors (14)Anna CioceGanka Bineva-Todd Anthony J Agbay Junwon Choi Thomas M Wood Marjoke F Debets[...]Omur Yilmaz TastanSvend Kjaer Jacob T Bush Carolyn R BertozziBen Schumann ACS Chemical Biology Published 15 October 2021 Crick labs/ facilitiesBen SchumannLuiz Pedro CarvalhoStructural BiologyLight MicroscopyCell ServicesFull details Generating orthogonal glycosyltransferase and nucleotide sugar pairs as next-generation glycobiology tools Authors (3)Anna Cioce Stacy A MalakerBen Schumann Current Opinion in Chemical Biology Published 1 February 2021 Crick labsBen SchumannFull details Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation Authors (27) Marjoke F DebetsOmur Yilmaz Tastan Simon P Wisnovsky Stacy A MalakerNikos Angelis Leonhard KR Moeckl[...] Michael C Bassik WE MoernerVivian Li Carolyn R BertozziBen Schumann Proceedings of the National Academy of Sciences of USA Published 13 October 2020 Crick labs/ facilitiesBen SchumannNeil McDonaldVivian LiLuiz Pedro CarvalhoStructural BiologyProteomicsCell ServicesFull details Open questions in chemical glycobiology Authors (2)Mia Zol-HanlonBen Schumann Communications Chemistry Published 7 August 2020 Crick labsBen SchumannFull details Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells Authors (17)Ben Schumann Stacy Alyse Malaker Simon Peter Wisnovsky Marjoke Froukje Debets Anthony John Agbay Daniel Fernandez[...] Melissa Anne Gray Kayvon Pedram Jennifer Jean Kohler Milan Mrksich Carolyn Ruth Bertozzi Molecular Cell Published 4 June 2020 Crick labs/ facilitiesBen SchumannCell ServicesFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Voices: Challenges and opportunities for bioorthogonal chemistry Authors (5) KL HsuBen Schumann E Sletten E Vinogradova P Zou Cell Chemical Biology Published 21 March 2024 Crick labsBen SchumannFull details
Cell scientist to watch – Ben Schumann Authors (2) Amelia GlazierBen Schumann Journal of Cell Science Published 1 November 2023 Crick labsBen SchumannFull details
Molecular mechanism of decision-making in glycosaminoglycan biosynthesis Authors (8) Douglas Sammon Anja Krueger Marta Busse-Wicher Rhodri Marc Morgan Stuart M HaslamBen SchumannDavid Briggs Erhard Hohenester Nature Communications Published 13 October 2023 Crick labs/ facilitiesBen SchumannNeil McDonaldChemical BiologyFull details
O-linked sialoglycans modulate the proteolysis of SARS-CoV-2 spike and likely contribute to the mutational trajectory in variants of concern Authors (22)Edgar Gonzalez-RodriguezMia Zol-HanlonGanka Bineva-ToddAndrea MarchesiMark Skehel Keira E Mahoney[...]Robert Wilkinson Emma C Wall Ramón Hurtado-Guerrero Stacy A MalakerBen Schumann ACS Central Science Published 22 March 2023 Crick labs/ facilitiesRobert J WilkinsonBen SchumannSteve GamblinStructural BiologyProteomicsChemical BiologyFull details
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth Authors (59) Emma Scott Kirsty HodgsonBea Calle Helen Turner Kathleen Cheung Abel Bermudez[...] Sharon Pitteri Ning Wang David J ElliottBen Schumann Jennifer Munkley Oncogene Published 16 March 2023 Crick labs/ facilitiesBen SchumannStructural BiologyFull details
Celebrating the contributions of Carolyn Bertozzi to bioorthogonal chemistry and its application to glycoscience Authors (3) Jessica R Kramer Matthew R PrattBen Schumann Israel Journal of Chemistry Published 1 February 2023 Crick labsBen SchumannFull details
Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells Authors (10)Bea CalleEdgar Gonzalez-Rodriguez Keira E MahoneyAnna CioceGanka Bineva-ToddOmur Yilmaz TastanChloe Roustan Helen Flynn Stacy A MalakerBen Schumann STAR Protocols Published 17 March 2023 Crick labs/ facilitiesBen SchumannStructural BiologyProteomicsFull details
Cell-specific bioorthogonal tagging of glycoproteins Authors (31)Anna CioceBea CalleTatiana Rizou Sarah C LoweryVicky Bridgeman Keira E Mahoney[...] Stuart M Haslam Sabine L Flitsch Stacy A MalakerIlaria MalanchiBen Schumann Nature Communications Published 25 October 2022 Crick labs/ facilitiesJernej UleBen SchumannIlaria MalanchiLuiz Pedro CarvalhoStructural BiologyProteomicsBioinformatics and BiostatisticsLight MicroscopyCell ServicesBiological Research FacilityAdvanced SequencingFull details
4-deoxy-4-fluoro-GalNAz (4FGalNAz) is a metabolic chemical reporter of O-GlcNAc modifications, highlighting the notable substrate flexibility of O-GlcNAc transferase Authors (15) Emma G Jackson Giuliano Cutolo Bo Yang Nageswari Yarravarapu Mary WN BurnsGanka Bineva-Todd[...] Hazel M HoldenBen Schumann Jennifer J Kohler Christina M Woo Matthew R Pratt ACS Chemical Biology Published 21 January 2022 Crick labs/ facilitiesBen SchumannStructural BiologyFull details
Benefits of chemical sugar modifications introduced by click chemistry for glycoproteomic analyses Authors (11)Bea CalleGanka Bineva-ToddAndrea Marchesi Helen Flynn Mattia GhirardelloOmur Yilmaz TastanChloe Roustan Junwon Choi M Carmen GalanBen Schumann Stacy A Malaker Journal of the American Society for Mass Spectrometry Published 1 September 2021 Crick labs/ facilitiesBen SchumannStructural BiologyProteomicsMetabolomicsFull details
Optimization of metabolic oligosaccharide engineering with Ac4GalNAlk and Ac4GlcNAlk by an engineered pyrophosphorylase Authors (14)Anna CioceGanka Bineva-Todd Anthony J Agbay Junwon Choi Thomas M Wood Marjoke F Debets[...]Omur Yilmaz TastanSvend Kjaer Jacob T Bush Carolyn R BertozziBen Schumann ACS Chemical Biology Published 15 October 2021 Crick labs/ facilitiesBen SchumannLuiz Pedro CarvalhoStructural BiologyLight MicroscopyCell ServicesFull details
Generating orthogonal glycosyltransferase and nucleotide sugar pairs as next-generation glycobiology tools Authors (3)Anna Cioce Stacy A MalakerBen Schumann Current Opinion in Chemical Biology Published 1 February 2021 Crick labsBen SchumannFull details
Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation Authors (27) Marjoke F DebetsOmur Yilmaz Tastan Simon P Wisnovsky Stacy A MalakerNikos Angelis Leonhard KR Moeckl[...] Michael C Bassik WE MoernerVivian Li Carolyn R BertozziBen Schumann Proceedings of the National Academy of Sciences of USA Published 13 October 2020 Crick labs/ facilitiesBen SchumannNeil McDonaldVivian LiLuiz Pedro CarvalhoStructural BiologyProteomicsCell ServicesFull details
Open questions in chemical glycobiology Authors (2)Mia Zol-HanlonBen Schumann Communications Chemistry Published 7 August 2020 Crick labsBen SchumannFull details
Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells Authors (17)Ben Schumann Stacy Alyse Malaker Simon Peter Wisnovsky Marjoke Froukje Debets Anthony John Agbay Daniel Fernandez[...] Melissa Anne Gray Kayvon Pedram Jennifer Jean Kohler Milan Mrksich Carolyn Ruth Bertozzi Molecular Cell Published 4 June 2020 Crick labs/ facilitiesBen SchumannCell ServicesFull details