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Breadcrumb Caetano Reis e Sousa Reis e Sousa lab Immunobiology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies News Alumni Dendritic cells are white blood cells that get their name from their tree-like shape (dendron is the Greek word for tree). 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(4)Current Opinion in Immunology (3)eLife (3)Nature Immunology (3)Science Immunology (3)Annual Review of Immunology (2)Blood (2)Cell Reports (2)Journal of Clinical Investigation (2)Nature (2)Nature Communications (2)BioEssays (1)Cell Host & Microbe (1)Current Opinion in Microbiology (1)EMBO Molecular Medicine (1)European Journal of Clinical Investigation (1)Frontiers in Immunology (1)Immunological Reviews (1)Journal of Experimental Medicine (1)Nature Biotechnology (1)Oncoimmunology (1)Open Biol (1)PLOS Pathogens (1)Proceedings of the National Academy of Sciences of the United States of America (1)Seminars in Immunology (1)The EMBO Journal (1)The Lancet (1)Trends in Cancer (1)Trends in Immunology (1)Wellcome Open Research (1) Facet Journal Publications Displaying 1 - 20 of 83Last updated : 15 August 2022 03:20 RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency Authors (8)Caetano Reis e Sousa Jorn E Stok Timo Oosenbrug Laurens R ter Haar Dennis Gravekamp Christian P Bromley Santiago Zelenay Annemarthe G van der Veen The EMBO Journal Published 15 March 2022 Crick labsCaetano Reis e SousaFull details Epithelial colonization by gut dendritic cells promotes their functional diversification Authors (23)Mar Cabeza CabrerizoCaetano Reis e Sousa Claudia A Rivera Violaine Randrian Wilfrid Richer Yohan Gerber-Ferder[...] Hélène D Moreau Julie Helft Danijela Matic Vignjevic Eduardo J Villablanca Ana-Maria Lennon-Duménil Immunity Published 11 January 2022 Crick labsCaetano Reis e SousaFull details Maintenance and loss of endocytic organelle integrity: mechanisms and implications for antigen cross-presentation Authors (4)Eleanor ChildsConor Henry Johnathan CantonCaetano Reis e Sousa Open Biol Published 10 November 2021 Crick labsCaetano Reis e SousaFull details Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity Authors (18)Mar Cabeza CabrerizoCarlos Munoz MinuttiAna Matos Cardoso Da SilvaRob JenkinsJustina KulikauskaiteMichael Buck[...]Caetano Reis e Sousa Mariana Pereira da Costa Hector Huerga Encabo Judith E Allen Manolis Pasparakis Science Immunology Published 5 November 2021 Crick labs/ facilitiesAndreas WackErik SahaiCaetano Reis e SousaJohn McCauleyDominique BonnetWorldwide Influenza CentreFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsFull details From mRNA sensing to vaccines Authors (9) Anthony S Fauci Miriam Merad Soumya Swaminathan Sun Hur Eric Topol Kate FitzgeraldCaetano Reis e Sousa Kizzmekia S Corbett Stefan Bauer Immunity Published 14 December 2021 Crick labsCaetano Reis e SousaFull details An isoform of Dicer protects mammalian stem cells against multiple RNA viruses Authors (10)Enzo PoirierMichael Buck Probir ChakravartyJoana Do Vale Viegas Silva CarvalhoBruno Goncalves FredericoAna Matos Cardoso Da SilvaLyn HealyRachel UlfertsRupert BealeCaetano Reis e Sousa Science Published 9 July 2021 Crick labs/ facilitiesCaetano Reis e SousaRupert BealeHuman Embryonic Stem CellExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryAdvanced SequencingFull details Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity Authors (17)Evangelos GiampazoliasOliver SchulzJonathan LimNeil Rogers Probir Chakravarty Naren Srinivasan[...] Stefano Sammicheli Natalia MoncautSunita Varsani-BrownIan RosewellCaetano Reis e Sousa Cell Published 22 July 2021 Crick labs/ facilitiesCaetano Reis e SousaGenetic Modification ServiceBiological Research FacilityBioinformatics and BiostatisticsFlow CytometryFull details Dendritic cells revisited Authors (5)Mar Cabeza CabrerizoAna Matos Cardoso Da SilvaCarlos Munoz MinuttiMariana Pereira Da CostaCaetano Reis e Sousa Annual Review of Immunology Published 1 April 2021 Crick labsCaetano Reis e SousaFull details SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay Authors (40)Michael BuckEnzo PoirierAna Matos Cardoso Da SilvaBruno Goncalves Frederico J CantonSam Barrell[...] I Martini D Miller D Moore A Oomatia The Crick COVID-19 Consortium Wellcome Open Research Published 21 May 2021 Crick labs/ facilitiesSamra TurajlicCharles SwantonCaetano Reis e SousaGeorge KassiotisSonia GandhiRupert BealePeptide ChemistryMetabolomicsHigh Throughput ScreeningGenetic Modification ServiceBiological Research FacilityAdvanced SequencingStructural BiologyScientific computingFull details The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens Authors (18) Johnathan CantonHanna BleesConor HenryMichael BuckOliver SchulzNeil Rogers[...] Andres Alloatti Cara J Ellison Sebastian Amigorena David C Thomas Felix Randow Nature Immunology Published 1 February 2021 Crick labs/ facilitiesCaetano Reis e SousaFlow CytometryElectron MicroscopyProteomicsBiological Research FacilityFull details Antagonistic inflammatory phenotypes dictate tumor fate and response to immune checkpoint blockade Authors (20) Eduardo Bonavita Christian P Bromley Gustav Jonsson Victoria S Pelly Sudhakar Sahoo Katherine Walwyn-Brown[...] Alberto MantovaniCaetano Reis e Sousa Nadia Guerra Daniel M Davis Santiago Zelenay Immunity Published 15 December 2020 Crick labsCaetano Reis e SousaFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyPeptide ChemistryMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenomics/Equipment ParkGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Cross-presentation of dead-cell-associated antigens by DNGR-1+ dendritic cells contributes to chronic allograft rejection in mice Authors (13) Janneke van BlijswijkSonia LeeCaetano Reis e Sousa Saidou Balam Rebecca Kesselring Eggenhofer Elke[...] Matthias Evert Hans J Schlitt Edward K Geissler Stefan M Brunner Stefan Fichtner-Feigl European Journal of Immunology Published 1 December 2020 Crick labsCaetano Reis e SousaFull details Scalable and robust SARS-CoV-2 testing in an academic center Authors (81)Rupert BealePeter CherepanovSteve GamblinSonia Gandhi Jacki GoldmanSteve Hindmarsh[...] Amy Strange Melanie Turner Sophia Ward Wai Keong Wong The Crick COVID-19 Consortium Nature Biotechnology Published 1 August 2020 Crick labs/ facilitiesAndreas WackJames TurnerCharles SwantonCaetano Reis e SousaPeter RatcliffeVenizelos PapayannopoulosGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeStructural BiologyPeptide ChemistryMetabolomicsHigh Throughput ScreeningGenomics/Equipment ParkGenetic Modification ServiceFermentationBiological Research FacilityAdvanced SequencingScientific computingFull details Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) Authors (436) Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages[...] Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky European Journal of Immunology Published 21 October 2019 Crick labs/ facilitiesRobert J WilkinsonCaetano Reis e SousaFlow CytometryFull details Cytoskeletal exposure in the regulation of immunity and initiation of tissue repair Authors (2)Oliver GordonCaetano Reis e Sousa BioEssays Published 1 July 2019 Crick labsCaetano Reis e SousaFull details Slicing and dicing viruses: antiviral RNA interference in mammals Authors (4) Pierre V Maillard Annemarthe G van der VeenEnzo PoirierCaetano Reis e Sousa EMBO Journal Published 15 April 2019 Crick labsCaetano Reis e SousaFull details Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors Authors (19)Mar Cabeza Cabrerizo Janneke van BlijswijkRob Jenkins Probir ChakravartyNeil RogersBruno Goncalves Frederico[...] Barbara U Schraml Marc Bajénoff Michael Gerner Ronald N Germain Frederick Klauschen Science Immunology Published 1 March 2019 Crick labs/ facilitiesErik SahaiCaetano Reis e SousaBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityFull details Direct reprogramming of fibroblasts into antigen-presenting dendritic cells Authors (13)Oliver SchulzCaetano Reis e Sousa Fábio F Rosa Cristiana F Pires Ilia Kurochkin Alexandra G Ferreira[...] Kritika Shaiv Laura Solanas Cláudia Azenha Dmitri Papatsenko Carlos-Filipe Pereira Science Immunology Published 7 December 2018 Crick labsCaetano Reis e SousaFull details The role of type 1 conventional dendritic cells in cancer immunity Authors (2) Jan P BöttcherCaetano Reis e Sousa Trends in Cancer Published 1 November 2018 Crick labsCaetano Reis e SousaFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency Authors (8)Caetano Reis e Sousa Jorn E Stok Timo Oosenbrug Laurens R ter Haar Dennis Gravekamp Christian P Bromley Santiago Zelenay Annemarthe G van der Veen The EMBO Journal Published 15 March 2022 Crick labsCaetano Reis e SousaFull details
Epithelial colonization by gut dendritic cells promotes their functional diversification Authors (23)Mar Cabeza CabrerizoCaetano Reis e Sousa Claudia A Rivera Violaine Randrian Wilfrid Richer Yohan Gerber-Ferder[...] Hélène D Moreau Julie Helft Danijela Matic Vignjevic Eduardo J Villablanca Ana-Maria Lennon-Duménil Immunity Published 11 January 2022 Crick labsCaetano Reis e SousaFull details
Maintenance and loss of endocytic organelle integrity: mechanisms and implications for antigen cross-presentation Authors (4)Eleanor ChildsConor Henry Johnathan CantonCaetano Reis e Sousa Open Biol Published 10 November 2021 Crick labsCaetano Reis e SousaFull details
Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity Authors (18)Mar Cabeza CabrerizoCarlos Munoz MinuttiAna Matos Cardoso Da SilvaRob JenkinsJustina KulikauskaiteMichael Buck[...]Caetano Reis e Sousa Mariana Pereira da Costa Hector Huerga Encabo Judith E Allen Manolis Pasparakis Science Immunology Published 5 November 2021 Crick labs/ facilitiesAndreas WackErik SahaiCaetano Reis e SousaJohn McCauleyDominique BonnetWorldwide Influenza CentreFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsFull details
From mRNA sensing to vaccines Authors (9) Anthony S Fauci Miriam Merad Soumya Swaminathan Sun Hur Eric Topol Kate FitzgeraldCaetano Reis e Sousa Kizzmekia S Corbett Stefan Bauer Immunity Published 14 December 2021 Crick labsCaetano Reis e SousaFull details
An isoform of Dicer protects mammalian stem cells against multiple RNA viruses Authors (10)Enzo PoirierMichael Buck Probir ChakravartyJoana Do Vale Viegas Silva CarvalhoBruno Goncalves FredericoAna Matos Cardoso Da SilvaLyn HealyRachel UlfertsRupert BealeCaetano Reis e Sousa Science Published 9 July 2021 Crick labs/ facilitiesCaetano Reis e SousaRupert BealeHuman Embryonic Stem CellExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryAdvanced SequencingFull details
Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity Authors (17)Evangelos GiampazoliasOliver SchulzJonathan LimNeil Rogers Probir Chakravarty Naren Srinivasan[...] Stefano Sammicheli Natalia MoncautSunita Varsani-BrownIan RosewellCaetano Reis e Sousa Cell Published 22 July 2021 Crick labs/ facilitiesCaetano Reis e SousaGenetic Modification ServiceBiological Research FacilityBioinformatics and BiostatisticsFlow CytometryFull details
Dendritic cells revisited Authors (5)Mar Cabeza CabrerizoAna Matos Cardoso Da SilvaCarlos Munoz MinuttiMariana Pereira Da CostaCaetano Reis e Sousa Annual Review of Immunology Published 1 April 2021 Crick labsCaetano Reis e SousaFull details
SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay Authors (40)Michael BuckEnzo PoirierAna Matos Cardoso Da SilvaBruno Goncalves Frederico J CantonSam Barrell[...] I Martini D Miller D Moore A Oomatia The Crick COVID-19 Consortium Wellcome Open Research Published 21 May 2021 Crick labs/ facilitiesSamra TurajlicCharles SwantonCaetano Reis e SousaGeorge KassiotisSonia GandhiRupert BealePeptide ChemistryMetabolomicsHigh Throughput ScreeningGenetic Modification ServiceBiological Research FacilityAdvanced SequencingStructural BiologyScientific computingFull details
The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens Authors (18) Johnathan CantonHanna BleesConor HenryMichael BuckOliver SchulzNeil Rogers[...] Andres Alloatti Cara J Ellison Sebastian Amigorena David C Thomas Felix Randow Nature Immunology Published 1 February 2021 Crick labs/ facilitiesCaetano Reis e SousaFlow CytometryElectron MicroscopyProteomicsBiological Research FacilityFull details
Antagonistic inflammatory phenotypes dictate tumor fate and response to immune checkpoint blockade Authors (20) Eduardo Bonavita Christian P Bromley Gustav Jonsson Victoria S Pelly Sudhakar Sahoo Katherine Walwyn-Brown[...] Alberto MantovaniCaetano Reis e Sousa Nadia Guerra Daniel M Davis Santiago Zelenay Immunity Published 15 December 2020 Crick labsCaetano Reis e SousaFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyPeptide ChemistryMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenomics/Equipment ParkGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Cross-presentation of dead-cell-associated antigens by DNGR-1+ dendritic cells contributes to chronic allograft rejection in mice Authors (13) Janneke van BlijswijkSonia LeeCaetano Reis e Sousa Saidou Balam Rebecca Kesselring Eggenhofer Elke[...] Matthias Evert Hans J Schlitt Edward K Geissler Stefan M Brunner Stefan Fichtner-Feigl European Journal of Immunology Published 1 December 2020 Crick labsCaetano Reis e SousaFull details
Scalable and robust SARS-CoV-2 testing in an academic center Authors (81)Rupert BealePeter CherepanovSteve GamblinSonia Gandhi Jacki GoldmanSteve Hindmarsh[...] Amy Strange Melanie Turner Sophia Ward Wai Keong Wong The Crick COVID-19 Consortium Nature Biotechnology Published 1 August 2020 Crick labs/ facilitiesAndreas WackJames TurnerCharles SwantonCaetano Reis e SousaPeter RatcliffeVenizelos PapayannopoulosGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeStructural BiologyPeptide ChemistryMetabolomicsHigh Throughput ScreeningGenomics/Equipment ParkGenetic Modification ServiceFermentationBiological Research FacilityAdvanced SequencingScientific computingFull details
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) Authors (436) Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages[...] Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky European Journal of Immunology Published 21 October 2019 Crick labs/ facilitiesRobert J WilkinsonCaetano Reis e SousaFlow CytometryFull details
Cytoskeletal exposure in the regulation of immunity and initiation of tissue repair Authors (2)Oliver GordonCaetano Reis e Sousa BioEssays Published 1 July 2019 Crick labsCaetano Reis e SousaFull details
Slicing and dicing viruses: antiviral RNA interference in mammals Authors (4) Pierre V Maillard Annemarthe G van der VeenEnzo PoirierCaetano Reis e Sousa EMBO Journal Published 15 April 2019 Crick labsCaetano Reis e SousaFull details
Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors Authors (19)Mar Cabeza Cabrerizo Janneke van BlijswijkRob Jenkins Probir ChakravartyNeil RogersBruno Goncalves Frederico[...] Barbara U Schraml Marc Bajénoff Michael Gerner Ronald N Germain Frederick Klauschen Science Immunology Published 1 March 2019 Crick labs/ facilitiesErik SahaiCaetano Reis e SousaBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityFull details
Direct reprogramming of fibroblasts into antigen-presenting dendritic cells Authors (13)Oliver SchulzCaetano Reis e Sousa Fábio F Rosa Cristiana F Pires Ilia Kurochkin Alexandra G Ferreira[...] Kritika Shaiv Laura Solanas Cláudia Azenha Dmitri Papatsenko Carlos-Filipe Pereira Science Immunology Published 7 December 2018 Crick labsCaetano Reis e SousaFull details
The role of type 1 conventional dendritic cells in cancer immunity Authors (2) Jan P BöttcherCaetano Reis e Sousa Trends in Cancer Published 1 November 2018 Crick labsCaetano Reis e SousaFull details