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Breadcrumb Charles Swanton Swanton lab Cancer Evolution and Genome Instability Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Illustration of chromosomes from a cancer cell showing large-scale alterations. Toggle to view hero caption PublicationsYear published2024 (1)2023 (3)2022 (1)2021 (3)2020 (3) Facet Year publishedResearch topicsChemical Biology & High Throughput (11)Computational & Systems Biology (11)Genetics & Genomics (11)Genome Integrity & Repair (11)Human Biology & Physiology (11)Signalling & Oncogenes (11)Tumour Biology (11)Immunology (5)Model Organisms (5)Cell Biology (4)Cell Cycle & Chromosomes (4)Stem Cells (4)Biochemistry & Proteomics (3)Developmental Biology (3)Infectious Disease (3)Metabolism (3)Neurosciences (3)Structural Biology & Biophysics (3)Imaging (1) Facet Research topicsPublication typeJournal article (11)Primary research (7)Review (2)Biography (1)Commentary (1) Facet Publication typeJournal (-)Nature Cancer (11) Facet Journal Publications Displaying 1 - 11 of 11Last updated : 24 April 2024 03:10 The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma Authors (20) Xiaoxi Pan Khalid AbdulJabbar Jose Coelho-Lima Anca-Ioana Grapa Hanyun Zhang Alvin Ho Kwan Cheung[...] TRACERx ConsortiumCharles Swanton Yinyin Yuan John Le Quesne David A Moore Nature Cancer Published 1 February 2024 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonErik SahaiGeorge KassiotisFlow CytometryExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Breaking the performance ceiling for neoantigen immunogenicity prediction Authors (12) Hugh O'Brien Max Salm Laura Morton Maciej Szukszto Felix O'Farrell Charlotte Boulton[...] Yardena SamuelsCharles Swanton Marc R Mansour Sine Reker Hadrup Sergio A Quezada Nature Cancer Published 1 December 2023 Crick labsCharles SwantonFull details Turning a failing PhD around Authors (1)Charles Swanton Nature Cancer Published 1 October 2023 Crick labsCharles SwantonFull details The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC Authors (30) Aaron Javitt Merav D Shmueli Matthias P Kramer Aleksandra A Kolodziejczyk Ivan J Cohen Lihi Radomir[...] Paula CA da Fonseca Eran Elinav Nir Friedman Silke Meiners Yifat Merbl Nature Cancer Published 22 May 2023 Crick labsCharles SwantonFull details A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer Authors (21) Yin WuDhruva Biswas Ieva UsaiteMihaela AngelovaStefan BoeingTakahiro Karasaki[...] Mariam Jamal-Hanjani Allan Hackshaw Sergio A QuezadaAdrian HaydayCharles Swanton Nature Cancer Published 1 June 2022 Crick labs/ facilitiesCharles SwantonAdrian HaydayBioinformatics and BiostatisticsFull details Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study Authors (98)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary WuFiona Byrne[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE Consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study Authors (98)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary WuFiona Byrne[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic The CAPTURE Consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study Authors (89)Annika FendlerLewis AuScott ShepherdFiona ByrneMaddalena Cerrone Laura Amanda Boos[...]George Kassiotis James LarkinRobert WilkinsonSamra Turajlic The CAPTURE consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinWorldwide Influenza CentreProteomicsMetabolomicsHigh Throughput ScreeningFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details The T cell differentiation landscape is shaped by tumour mutations in lung cancer Authors (51) Ehsan Ghorani James L Reading Jake Y Henry Marc Robert de Massy Rachel Rosenthal Virginia Turati[...] Karl S Peggs Nicholas McGranahan Benny Chain Charles Swanton Sergio A Quezada Nature Cancer Published 1 May 2020 Crick labsPeter Van LooCharles SwantonFull details Securing the future of the clinician-scientist Authors (8) Karen Noble Joanna Owens Fabrice André Samuel F Bakhoum Sherene Loi Hans Christian Reinhardt David TuvesonCharles Swanton Nature Cancer Published 1 February 2020 Crick labsCharles SwantonFull details Intratumor heterogeneity reflects clinical disease course Authors (3) Christine A Iacobuzio-Donahue Kevin LitchfieldCharles Swanton Nature Cancer Published 13 January 2020 Crick labsCharles SwantonFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma Authors (20) Xiaoxi Pan Khalid AbdulJabbar Jose Coelho-Lima Anca-Ioana Grapa Hanyun Zhang Alvin Ho Kwan Cheung[...] TRACERx ConsortiumCharles Swanton Yinyin Yuan John Le Quesne David A Moore Nature Cancer Published 1 February 2024 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonErik SahaiGeorge KassiotisFlow CytometryExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Breaking the performance ceiling for neoantigen immunogenicity prediction Authors (12) Hugh O'Brien Max Salm Laura Morton Maciej Szukszto Felix O'Farrell Charlotte Boulton[...] Yardena SamuelsCharles Swanton Marc R Mansour Sine Reker Hadrup Sergio A Quezada Nature Cancer Published 1 December 2023 Crick labsCharles SwantonFull details
Turning a failing PhD around Authors (1)Charles Swanton Nature Cancer Published 1 October 2023 Crick labsCharles SwantonFull details
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC Authors (30) Aaron Javitt Merav D Shmueli Matthias P Kramer Aleksandra A Kolodziejczyk Ivan J Cohen Lihi Radomir[...] Paula CA da Fonseca Eran Elinav Nir Friedman Silke Meiners Yifat Merbl Nature Cancer Published 22 May 2023 Crick labsCharles SwantonFull details
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer Authors (21) Yin WuDhruva Biswas Ieva UsaiteMihaela AngelovaStefan BoeingTakahiro Karasaki[...] Mariam Jamal-Hanjani Allan Hackshaw Sergio A QuezadaAdrian HaydayCharles Swanton Nature Cancer Published 1 June 2022 Crick labs/ facilitiesCharles SwantonAdrian HaydayBioinformatics and BiostatisticsFull details
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study Authors (98)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary WuFiona Byrne[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE Consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study Authors (98)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary WuFiona Byrne[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic The CAPTURE Consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study Authors (89)Annika FendlerLewis AuScott ShepherdFiona ByrneMaddalena Cerrone Laura Amanda Boos[...]George Kassiotis James LarkinRobert WilkinsonSamra Turajlic The CAPTURE consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinWorldwide Influenza CentreProteomicsMetabolomicsHigh Throughput ScreeningFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
The T cell differentiation landscape is shaped by tumour mutations in lung cancer Authors (51) Ehsan Ghorani James L Reading Jake Y Henry Marc Robert de Massy Rachel Rosenthal Virginia Turati[...] Karl S Peggs Nicholas McGranahan Benny Chain Charles Swanton Sergio A Quezada Nature Cancer Published 1 May 2020 Crick labsPeter Van LooCharles SwantonFull details
Securing the future of the clinician-scientist Authors (8) Karen Noble Joanna Owens Fabrice André Samuel F Bakhoum Sherene Loi Hans Christian Reinhardt David TuvesonCharles Swanton Nature Cancer Published 1 February 2020 Crick labsCharles SwantonFull details
Intratumor heterogeneity reflects clinical disease course Authors (3) Christine A Iacobuzio-Donahue Kevin LitchfieldCharles Swanton Nature Cancer Published 13 January 2020 Crick labsCharles SwantonFull details