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Breadcrumb Charles Swanton Swanton lab Cancer Evolution and Genome Instability Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Illustration of chromosomes from a cancer cell showing large-scale alterations. Toggle to view hero caption PublicationsYear published2023 (3)2022 (2)2021 (2)2020 (2)2018 (2)2017 (1)2015 (1)2014 (1) Facet Year publishedResearch topicsChemical Biology & High Throughput (12)Computational & Systems Biology (12)Genetics & Genomics (12)Genome Integrity & Repair (12)Human Biology & Physiology (12)Signalling & Oncogenes (12)Tumour Biology (12)Immunology (3)Model Organisms (3)Biochemistry & Proteomics (2)Cell Biology (2)Cell Cycle & Chromosomes (2)Developmental Biology (2)Infectious Disease (2)Metabolism (2)Neurosciences (2)Stem Cells (2)Structural Biology & Biophysics (2)Gene Expression (1)Imaging (1)Synthetic Biology (1) Facet Research topicsPublication typeJournal article (14)Primary research (8)Review (3)Commentary (1)Letter (1)Obituary (1) Facet Publication typeJournal (-)Cancer Cell (14) Facet Journal Publications Displaying 1 - 14 of 14Last updated : 29 March 2024 03:08 Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer Authors (29) Clare E Weeden Velimir Gayevskiy Claire Marceaux Daniel Batey Tania Tan Kenta Yokote[...] Claire L Gordon Laura K Mackay Terence P Speed Daniel HD Gray Marie-Liesse Asselin-Labat Cancer Cell Published 8 May 2023 Crick labsCharles SwantonFull details Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer Authors (67)Mary WuScott Shepherd Annika FendlerEdward CarrLewis Au Ruth Harvey[...] Emma Nicholson James Larkin Emma C WallSamra Turajlic CAPTURE consortium Cancer Cell Published 8 May 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer Authors (26) Balaji Virassamy Franco Caramia Peter Savas Sneha Sant Jianan Wang Susan N Christo[...] Terence P Speed Phillip K Darcy Paul J Neeson Laura K Mackay Sherene Loi Cancer Cell Published 13 March 2023 Crick labsCharles SwantonFull details Evaluation of cell-free DNA approaches for multi-cancer early detection Authors (49) Arash Jamshidi Minetta C Liu Eric A Klein Oliver Venn Earl Hubbell John F Beausang[...] Mikkael A Sekeres Alan Bryce Alexander M Aravanis Michael V SeidenCharles Swanton Cancer Cell Published 12 December 2022 Crick labsCharles SwantonFull details The translational challenges of precision oncology Authors (6) Oriol Pich Chris BaileyTom Watkins Simone Zaccaria Mariam Jamal-HanjaniCharles Swanton Cancer Cell Published 9 May 2022 Crick labsCharles SwantonFull details Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer Authors (65)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary Wu Andreas M Schmitt[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE consortium Cancer Cell Published 14 February 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyProteomicsMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma Authors (207)Lewis Au Emine Hatipoglu Marc Robert de MassyKevin Litchfield Gordon BeattieAndrew Rowan[...] Jonathon Olsburgh Alexander Polson Sarah Rudman Mary Varia Hema Verma Cancer Cell Published 8 November 2021 Crick labs/ facilitiesSamra TurajlicCharles SwantonGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFull details Angelika Amon (1967-2020) Authors (1)Charles Swanton Cancer Cell Published 14 December 2020 Crick labsCharles SwantonFull details Cancer screening, surrogates of survival, and the soma Authors (4) James DeGregori Paul Pharoah Peter SasieniCharles Swanton Cancer Cell Published 12 October 2020 Crick labsCharles SwantonFull details Genomic features of response to combination immunotherapy in patients with advanced non-small-cell lung cancer Authors (32) Matthew D Hellmann Tavi Nathanson Hira Rizvi Benjamin C Creelan Francisco Sanchez-Vega Arun Ahuja[...] Jeff Hammerbacher Taha Merghoub Nicholas McGranahan Alexandra Snyder Jedd D Wolchok Cancer Cell Published 14 May 2018 Crick labsCharles SwantonFull details Fc effector function contributes to the activity of human anti-CTLA-4 antibodies Authors (35) Frederick Arce Vargas Andrew JS FurnessKevin Litchfield Kroopa JoshiRachel Rosenthal Ehsan Ghorani[...] James LarkinSamra TurajlicCharles Swanton Karl S Peggs Sergio A Quezada Cancer Cell Published 9 April 2018 Crick labsSamra TurajlicCharles SwantonFull details BCL9L dysfunction impairs caspase-2 expression permitting aneuploidy tolerance in colorectal cancer Authors (23) Carlos López-Garcia Laurent Sansregret Enric Domingo Nicholas McGranahanSebastijan HoborNicolai Birkbak[...]Aengus Stewart Havard Danielsen Marco Novelli Ian TomlinsonCharles Swanton Cancer Cell Published 9 January 2017 Crick labs/ facilitiesCharles SwantonExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingHigh Throughput ScreeningFlow CytometryCell ServicesBiological Research FacilityAdvanced SequencingFull details Biological and therapeutic impact of intratumor heterogeneity in cancer evolution Authors (2) Nicholas McGranahanCharles Swanton Cancer Cell Published 12 January 2015 Crick labsCharles SwantonFull details Epigenetic noise fuels cancer evolution Authors (2)Charles Swanton Stephan Beck Cancer Cell Published 8 December 2014 Crick labsCharles SwantonFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer Authors (29) Clare E Weeden Velimir Gayevskiy Claire Marceaux Daniel Batey Tania Tan Kenta Yokote[...] Claire L Gordon Laura K Mackay Terence P Speed Daniel HD Gray Marie-Liesse Asselin-Labat Cancer Cell Published 8 May 2023 Crick labsCharles SwantonFull details
Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer Authors (67)Mary WuScott Shepherd Annika FendlerEdward CarrLewis Au Ruth Harvey[...] Emma Nicholson James Larkin Emma C WallSamra Turajlic CAPTURE consortium Cancer Cell Published 8 May 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details
Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer Authors (26) Balaji Virassamy Franco Caramia Peter Savas Sneha Sant Jianan Wang Susan N Christo[...] Terence P Speed Phillip K Darcy Paul J Neeson Laura K Mackay Sherene Loi Cancer Cell Published 13 March 2023 Crick labsCharles SwantonFull details
Evaluation of cell-free DNA approaches for multi-cancer early detection Authors (49) Arash Jamshidi Minetta C Liu Eric A Klein Oliver Venn Earl Hubbell John F Beausang[...] Mikkael A Sekeres Alan Bryce Alexander M Aravanis Michael V SeidenCharles Swanton Cancer Cell Published 12 December 2022 Crick labsCharles SwantonFull details
The translational challenges of precision oncology Authors (6) Oriol Pich Chris BaileyTom Watkins Simone Zaccaria Mariam Jamal-HanjaniCharles Swanton Cancer Cell Published 9 May 2022 Crick labsCharles SwantonFull details
Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer Authors (65)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary Wu Andreas M Schmitt[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE consortium Cancer Cell Published 14 February 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyProteomicsMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma Authors (207)Lewis Au Emine Hatipoglu Marc Robert de MassyKevin Litchfield Gordon BeattieAndrew Rowan[...] Jonathon Olsburgh Alexander Polson Sarah Rudman Mary Varia Hema Verma Cancer Cell Published 8 November 2021 Crick labs/ facilitiesSamra TurajlicCharles SwantonGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFull details
Angelika Amon (1967-2020) Authors (1)Charles Swanton Cancer Cell Published 14 December 2020 Crick labsCharles SwantonFull details
Cancer screening, surrogates of survival, and the soma Authors (4) James DeGregori Paul Pharoah Peter SasieniCharles Swanton Cancer Cell Published 12 October 2020 Crick labsCharles SwantonFull details
Genomic features of response to combination immunotherapy in patients with advanced non-small-cell lung cancer Authors (32) Matthew D Hellmann Tavi Nathanson Hira Rizvi Benjamin C Creelan Francisco Sanchez-Vega Arun Ahuja[...] Jeff Hammerbacher Taha Merghoub Nicholas McGranahan Alexandra Snyder Jedd D Wolchok Cancer Cell Published 14 May 2018 Crick labsCharles SwantonFull details
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies Authors (35) Frederick Arce Vargas Andrew JS FurnessKevin Litchfield Kroopa JoshiRachel Rosenthal Ehsan Ghorani[...] James LarkinSamra TurajlicCharles Swanton Karl S Peggs Sergio A Quezada Cancer Cell Published 9 April 2018 Crick labsSamra TurajlicCharles SwantonFull details
BCL9L dysfunction impairs caspase-2 expression permitting aneuploidy tolerance in colorectal cancer Authors (23) Carlos López-Garcia Laurent Sansregret Enric Domingo Nicholas McGranahanSebastijan HoborNicolai Birkbak[...]Aengus Stewart Havard Danielsen Marco Novelli Ian TomlinsonCharles Swanton Cancer Cell Published 9 January 2017 Crick labs/ facilitiesCharles SwantonExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingHigh Throughput ScreeningFlow CytometryCell ServicesBiological Research FacilityAdvanced SequencingFull details
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution Authors (2) Nicholas McGranahanCharles Swanton Cancer Cell Published 12 January 2015 Crick labsCharles SwantonFull details
Epigenetic noise fuels cancer evolution Authors (2)Charles Swanton Stephan Beck Cancer Cell Published 8 December 2014 Crick labsCharles SwantonFull details