Publications

Cancer biomarkers: Emerging trends and clinical implications for personalized treatment

Authors (10)

Antonio Passaro
Maise Al Bakir
Emily G Hamilton
Maximilian Diehn
Fabrice André
Sinchita Roy-Chowdhuri
Giannis Mountzios
Ignacio I Wistuba
Charles Swanton
Solange Peters

Cell

Published 28 March 2024

Crick labs

Charles Swanton

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Embracing cancer complexity: Hallmarks of systemic disease

Authors (33)

Charles Swanton
Elsa Bernard
Chris Abbosh
Fabrice André
Johan Auwerx
Allan Balmain
[...]
Eileen White
Frank Winkler
John N Wood
Karen Vousden
Douglas Hanahan

Cell

Published 28 March 2024

Crick labs

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Impact of risk factors on early cancer evolution

Authors (5)

Cell

Published 13 April 2023

Crick labs

Charles Swanton

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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

Authors (121)

Stefan C Dentro
Ignaty Leshchiner
Kerstin Haase
Maxime Tarabichi
Jeff Wintersinger
Amit G Deshwar
[...]
Paul T Spellman
David C Wedge
Peter Van Loo
PCAWG Evolution and Heterogeneity Working Group
PCAWG Consortium

Cell

Published 15 April 2021

Crick labs/ facilities

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Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

Authors (28)

Kevin Litchfield
James L Reading
Clare Puttick
Krupa Thakkar
Chris Abbosh
Robert Bentham
[...]
Matthew D Hellmann
Samra Turajlic
Sergio A Quezada
Nicholas McGranahan
Charles Swanton

Cell

Published 4 February 2021

Crick labs

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Evidence that STK19 is not an NRAS-dependent melanoma driver

Authors (11)

Cell

Published 11 June 2020

Crick labs/ facilities

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UVB-induced tumor heterogeneity diminishes immune response in melanoma

Authors (29)

Yochai Wolf
Osnat Bartok
Sushant Patkar
Gitit Bar Eli
Sapir Cohen
Kevin Litchfield
[...]
Lea Eisenbach
Arie Admon
Charles Swanton
Eytan Ruppin
Yardena Samuels

Cell

Published 19 September 2019

Crick labs

Charles Swanton

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Deterministic evolutionary trajectories influence primary tumor growth: TRACERx Renal

Authors (71)

Samra Turajlic
Hang Xu
Kevin Litchfield
Andrew Rowan
Stuart Horswell
Tim Chambers
[...]
Peter Van Loo
Peter Campbell
James Larkin
Charles Swanton
TRACERx Renal Consortium

Cell

Published 19 April 2018

Crick labs/ facilities

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Timing the landmark events in the evolution of clear cell renal cell cancer: TRACERx Renal

Authors (48)

Thomas J Mitchell
Samra Turajlic
Andrew Rowan
David Nicol
James HR Farmery
Tim O'Brien
[...]
Andy G Lynch
Zoltan Szallasi
Charles Swanton
Peter J Campbell
TRACERx Renal Consortium

Cell

Published 19 April 2018

Crick labs/ facilities

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Tracking cancer evolution reveals constrained routes to metastases: TRACERx Renal

Authors (51)

Samra Turajlic
Hang Xu
Kevin Litchfield
Andrew Rowan
Tim Chambers
Jose I Lopez
[...]
Daniel L Burgess
Nelson R Alexander
Charles Swanton
PEACE
TRACERx Renal Consortium

Cell

Published 19 April 2018

Crick labs/ facilities

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Allele-specific HLA loss and immune escape in lung cancer evolution

Authors (12)

Nicholas McGranahan
Rachel Rosenthal
Crispin T Hiley
Andrew Rowan
Thomas BK Watkins
Gareth A Wilson
[...]
Selvaraju Veeriah
Peter Van Loo
Javier Herrero
Charles Swanton
TRACERx Consortium

Cell

Published 30 November 2017

Crick labs

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Cancer evolution constrained by the immune microenvironment

Authors (2)

Nicholas McGranahan
Charles Swanton

Cell

Published 24 August 2017

Crick labs

Charles Swanton

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Clonal heterogeneity and tumor evolution: past, present, and the future

Authors (2)

Nicholas McGranahan
Charles Swanton

Cell

Published 9 February 2017

Crick labs

Charles Swanton

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SnapShot: Renal cell carcinoma

Authors (3)

Cell

Published 3 December 2015

Crick labs

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Research case studies

Postdoctoral clinical fellows

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Cancer Evolution and Genome Instability Laboratory
: Publications

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Publications

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Research topics

Publication type

Journal

Cancer biomarkers: Emerging trends and clinical implications for personalized treatment

Embracing cancer complexity: Hallmarks of systemic disease

Impact of risk factors on early cancer evolution

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

Evidence that STK19 is not an NRAS-dependent melanoma driver

UVB-induced tumor heterogeneity diminishes immune response in melanoma

Deterministic evolutionary trajectories influence primary tumor growth: TRACERx Renal

Timing the landmark events in the evolution of clear cell renal cell cancer: TRACERx Renal

Tracking cancer evolution reveals constrained routes to metastases: TRACERx Renal

Allele-specific HLA loss and immune escape in lung cancer evolution

Cancer evolution constrained by the immune microenvironment

Clonal heterogeneity and tumor evolution: past, present, and the future

SnapShot: Renal cell carcinoma

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