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Breadcrumb Charles Swanton Swanton lab Cancer Evolution and Genome Instability Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Illustration of chromosomes from a cancer cell showing large-scale alterations. Toggle to view hero caption PublicationsYear published2023 (3)2022 (1)2021 (1)2020 (2)2019 (2)2018 (2)2017 (6)2016 (3)2015 (3)2014 (6)2013 (1)2011 (1) Facet Year publishedResearch topicsChemical Biology & High Throughput (23)Computational & Systems Biology (23)Genetics & Genomics (23)Genome Integrity & Repair (23)Human Biology & Physiology (23)Signalling & Oncogenes (23)Tumour Biology (23)Cell Biology (1)Imaging (1)Model Organisms (1) Facet Research topicsPublication typeJournal article (31) (-)Commentary (31) Facet Publication typeJournalLancet Oncology (3)Nature Reviews Clinical Oncology (3)Cancer Discovery (2)Nature (2)Annals of Oncology (1)Annals of Translational Medicine (1)BJU international (1)British Journal of Cancer (1)Cancer Cell (1)Cancer Prevention Research (1)Cancer Research (1)Cell (1)Cell Cycle (1)Clinical Chemistry (1)Current Biology (1)Disease Models & Mechanisms (1)European Journal of Cancer (1)Gastroenterology (1)Journal of Clinical Oncology (1)Nature Cancer (1)Nature Genetics (1)Nature Medicine (1)Nature Reviews Drug Discovery (1)Nature Reviews Urology (1)New England Journal of Medicine (1) Facet Journal Publications Displaying 1 - 20 of 31Last updated : 29 March 2024 02:25 Breaking the performance ceiling for neoantigen immunogenicity prediction Authors (12) Hugh O'Brien Max Salm Laura Morton Maciej Szukszto Felix O'Farrell Charlotte Boulton[...] Yardena SamuelsCharles Swanton Marc R Mansour Sine Reker Hadrup Sergio A Quezada Nature Cancer Published 1 December 2023 Crick labsCharles SwantonFull details Tumor heterogeneity impairs immunogenicity in mismatch repair deficient tumors Authors (3) James L ReadingDeborah CaswellCharles Swanton Nature Genetics Published 1 October 2023 Crick labsCharles SwantonFull details Distinct mutagenic activity of APOBEC3G cytidine deaminase identified in bladder cancer Authors (2)Deborah CaswellCharles Swanton Cancer Research Published 15 February 2023 Crick labsCharles SwantonFull details When can we be confident of surgical cure with ctDNA? Authors (2)Alexander Frankell Mariam Jamal-Hanjani Nature Reviews Clinical Oncology Published 1 September 2022 Crick labsCharles SwantonFull details Understanding the impact of immune-mediated selection on lung cancer evolution Authors (3)Rachel RosenthalCharles Swanton Nicholas McGranahan British Journal of Cancer Published 11 May 2021 Crick labsCharles SwantonFull details Take lessons from cancer evolution to the clinic Authors (1)Charles Swanton Nature Published 28 May 2020 Crick labsCharles SwantonFull details These cancer scientists turned their lab into a coronavirus-testing facility Authors (1) Noah Baker Nature Published 23 April 2020 Crick labsCharles SwantonFull details An emerging regulatory network of NHEJ via DYNLL1-mediated 53BP1 redistribution Authors (3)Lykourgos-Panagiotis ZalmasWei-Ting Lu Nnennaya Kanu Annals of Translational Medicine Published 1 July 2019 Crick labsCharles SwantonFull details Standing on the shoulders of giants Authors (1)Samra Turajlic Nature Medicine Published 6 March 2019 Crick labsSamra TurajlicCharles SwantonFull details The secret lives of cancer cell lines Authors (3)Rob Hynds Elina Vladimirou Sam M Janes Disease Models & Mechanisms Published 1 November 2018 Crick labsCharles SwantonFull details Immunotherapy for melanoma metastatic to the brain Authors (2)Samra Turajlic James Larkin New England Journal of Medicine Published 23 August 2018 Crick labsSamra TurajlicCharles SwantonFull details Cancer evolution constrained by the immune microenvironment Authors (2) Nicholas McGranahanCharles Swanton Cell Published 24 August 2017 Crick labsCharles SwantonFull details Evolution and cancer medicine - transformative insights Authors (3)Erik SahaiCharles Swanton CRUK Marshall Symposium Nature Reviews Clinical Oncology Published 22 August 2017 Crick labsCharles SwantonErik SahaiFull details Airway basal cell heterogeneity and lung squamous cell carcinoma Authors (2)Rob Hynds Sam M Janes Cancer Prevention Research Published 18 August 2017 Crick labsCharles SwantonFull details The GENIE is out of the bottle: landmark cancer genomics dataset released Authors (3) Kevin LitchfieldSamra TurajlicCharles Swanton Cancer Discovery Published 1 August 2017 Crick labsSamra TurajlicCharles SwantonFull details Implications of cancer evolution for drug development Authors (2)Samra TurajlicCharles Swanton Nature Reviews Drug Discovery Published 28 April 2017 Crick labsSamra TurajlicCharles SwantonFull details TRACERx Renal: tracking renal cancer evolution through therapy Authors (3)Samra TurajlicCharles Swanton TRACERx Renal Consortium Nature Reviews Urology Published 1 January 2017 Crick labsSamra TurajlicCharles SwantonFull details Systemic treatment of advanced papillary renal cell carcinoma: Where next? Authors (2)Samra Turajlic James Larkin European Journal of Cancer Published 4 November 2016 Crick labsSamra TurajlicCharles SwantonFull details Heterogeneity among liver cancer - a hurdle to optimizing therapy Authors (2)Nicolai Birkbak Jesper B Andersen Gastroenterology Published 26 February 2016 Crick labsCharles SwantonFull details Pruning cancer's evolutionary tree with lesion-directed therapy Authors (2) CT HileyCharles Swanton Cancer Discovery Published 1 February 2016 Crick labsCharles SwantonFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Breaking the performance ceiling for neoantigen immunogenicity prediction Authors (12) Hugh O'Brien Max Salm Laura Morton Maciej Szukszto Felix O'Farrell Charlotte Boulton[...] Yardena SamuelsCharles Swanton Marc R Mansour Sine Reker Hadrup Sergio A Quezada Nature Cancer Published 1 December 2023 Crick labsCharles SwantonFull details
Tumor heterogeneity impairs immunogenicity in mismatch repair deficient tumors Authors (3) James L ReadingDeborah CaswellCharles Swanton Nature Genetics Published 1 October 2023 Crick labsCharles SwantonFull details
Distinct mutagenic activity of APOBEC3G cytidine deaminase identified in bladder cancer Authors (2)Deborah CaswellCharles Swanton Cancer Research Published 15 February 2023 Crick labsCharles SwantonFull details
When can we be confident of surgical cure with ctDNA? Authors (2)Alexander Frankell Mariam Jamal-Hanjani Nature Reviews Clinical Oncology Published 1 September 2022 Crick labsCharles SwantonFull details
Understanding the impact of immune-mediated selection on lung cancer evolution Authors (3)Rachel RosenthalCharles Swanton Nicholas McGranahan British Journal of Cancer Published 11 May 2021 Crick labsCharles SwantonFull details
Take lessons from cancer evolution to the clinic Authors (1)Charles Swanton Nature Published 28 May 2020 Crick labsCharles SwantonFull details
These cancer scientists turned their lab into a coronavirus-testing facility Authors (1) Noah Baker Nature Published 23 April 2020 Crick labsCharles SwantonFull details
An emerging regulatory network of NHEJ via DYNLL1-mediated 53BP1 redistribution Authors (3)Lykourgos-Panagiotis ZalmasWei-Ting Lu Nnennaya Kanu Annals of Translational Medicine Published 1 July 2019 Crick labsCharles SwantonFull details
Standing on the shoulders of giants Authors (1)Samra Turajlic Nature Medicine Published 6 March 2019 Crick labsSamra TurajlicCharles SwantonFull details
The secret lives of cancer cell lines Authors (3)Rob Hynds Elina Vladimirou Sam M Janes Disease Models & Mechanisms Published 1 November 2018 Crick labsCharles SwantonFull details
Immunotherapy for melanoma metastatic to the brain Authors (2)Samra Turajlic James Larkin New England Journal of Medicine Published 23 August 2018 Crick labsSamra TurajlicCharles SwantonFull details
Cancer evolution constrained by the immune microenvironment Authors (2) Nicholas McGranahanCharles Swanton Cell Published 24 August 2017 Crick labsCharles SwantonFull details
Evolution and cancer medicine - transformative insights Authors (3)Erik SahaiCharles Swanton CRUK Marshall Symposium Nature Reviews Clinical Oncology Published 22 August 2017 Crick labsCharles SwantonErik SahaiFull details
Airway basal cell heterogeneity and lung squamous cell carcinoma Authors (2)Rob Hynds Sam M Janes Cancer Prevention Research Published 18 August 2017 Crick labsCharles SwantonFull details
The GENIE is out of the bottle: landmark cancer genomics dataset released Authors (3) Kevin LitchfieldSamra TurajlicCharles Swanton Cancer Discovery Published 1 August 2017 Crick labsSamra TurajlicCharles SwantonFull details
Implications of cancer evolution for drug development Authors (2)Samra TurajlicCharles Swanton Nature Reviews Drug Discovery Published 28 April 2017 Crick labsSamra TurajlicCharles SwantonFull details
TRACERx Renal: tracking renal cancer evolution through therapy Authors (3)Samra TurajlicCharles Swanton TRACERx Renal Consortium Nature Reviews Urology Published 1 January 2017 Crick labsSamra TurajlicCharles SwantonFull details
Systemic treatment of advanced papillary renal cell carcinoma: Where next? Authors (2)Samra Turajlic James Larkin European Journal of Cancer Published 4 November 2016 Crick labsSamra TurajlicCharles SwantonFull details
Heterogeneity among liver cancer - a hurdle to optimizing therapy Authors (2)Nicolai Birkbak Jesper B Andersen Gastroenterology Published 26 February 2016 Crick labsCharles SwantonFull details
Pruning cancer's evolutionary tree with lesion-directed therapy Authors (2) CT HileyCharles Swanton Cancer Discovery Published 1 February 2016 Crick labsCharles SwantonFull details