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Breadcrumb Charles Swanton Swanton lab Cancer Evolution and Genome Instability Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Illustration of chromosomes from a cancer cell showing large-scale alterations. Toggle to view hero caption PublicationsYear published (-)2013 (24) Facet Year publishedPublication typeJournal article (24)Primary research (13)Review (8)Letter (2)Commentary (1) Facet Publication typeJournalJournal of Pathology (3)Nature (3)American Journal of Pathology (1)Annals of Oncology (1)ASCO Educational Book (1)Breast Cancer Research (1)Breast Cancer Research and Treatment (1)British Journal of Cancer (1)Cancer Letters (1)Clinical Chemistry (1)Current Opinion in Pharmacology (1)Evolutionary Applications (1)Genome Medicine (1)Investigational New Drugs (1)Journal of Clinical Oncology (1)Nature Reviews Clinical Oncology (1)New England Journal of Medicine (1)Orvosi Hetilap (1)PLOS ONE (1)Scientific Reports (1) Facet Journal Publications Displaying 1 - 20 of 24Last updated : 28 March 2024 02:10 Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas Authors (17) Marco Gerlinger Sergio A Quezada Karl S Peggs Andrew JS Furness Rosalie Fisher Teresa Marafioti[...] Lisa Pickering Martin Gore David L Nicol James LarkinCharles Swanton Journal of Pathology Published 1 December 2013 Crick labsCharles SwantonFull details Cancer heterogeneity and "the struggle for existence": diagnostic and analytical challenges Authors (3) Stuart Horswell Nicholas MatthewsCharles Swanton Cancer Letters Published 1 November 2013 Crick labs/ facilitiesCharles SwantonBioinformatics and BiostatisticsAdvanced SequencingFull details HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis Authors (14) Carrie A Adelman Rafal L LoloNicolai Birkbak Olga Murina Kenichiro Matsuzaki Zuzana Horejsi[...] Gordon Stamp Alan D'Andrea Alessandro A SartoriCharles SwantonSimon Boulton Nature Published 17 October 2013 Crick labs/ facilitiesCharles SwantonSimon BoultonExperimental HistopathologyFull details Patupilone in patients with pretreated metastatic/locally recurrent colorectal cancer: results of the Phase II CINATRA trial Authors (13) SY Moorcraft I Chau C Peckitt D Cunningham S Rao KL Yim[...] G Stamp J Webb G Smith A GillbanksCharles Swanton Investigational New Drugs Published 1 October 2013 Crick labsCharles SwantonFull details Acquired resistance to crizotinib from a mutation in CD74-ROS1 Authors (3) Marco Gerlinger Larry NortonCharles Swanton New England Journal of Medicine Published 19 September 2013 Crick labsCharles SwantonFull details The causes and consequences of genetic heterogeneity in cancer evolution Authors (4) Rebecca A Burrell Nicholas McGranahan Jiri BartekCharles Swanton Nature Published 19 September 2013 Crick labsCharles SwantonFull details Parallel evolution of tumour subclones mimics diversity between tumours Authors (11) Pierre MartinezNicolai Birkbak Marco Gerlinger Nicholas McGranahan Rebecca A BurrellAndrew Rowan Tejal Joshi Rosalie Fisher James Larkin Zoltan SzallasiCharles Swanton Journal of Pathology Published 1 August 2013 Crick labsCharles SwantonFull details Tumour heterogeneity and immune-modulation Authors (5) Mariam Jamal-Hanjani Eirini Thanopoulou Karl S Peggs Sergio A QuezadaCharles Swanton Current Opinion in Pharmacology Published 1 August 2013 Crick labsCharles SwantonFull details Adapting clinical paradigms to the challenges of cancer clonal evolution Authors (3) Nirupa Murugaesu Su Kit ChewCharles Swanton American Journal of Pathology Published 1 June 2013 Crick labsCharles SwantonFull details Taxane benefit in breast cancer--a role for grade and chromosomal stability Authors (7) Roger P A'Hern Mariam Jamal-Hanjani A Marcell Szász Stephen RD Johnston Jorge S Reis-Filho Rebecca RoylanceCharles Swanton Nature Reviews Clinical Oncology Published 1 June 2013 Crick labsCharles SwantonFull details Egyszerűsített, alacsony költségű génexpressziós teszt az emlődaganatos betegségek kimenetelének előrejelzésére rutin patológiai blokkok felhasználásával [Simplified, low-cost gene expression profiling for the prediction of outcome in breast cancer based Authors (15) A Marcell Szász Balázs Ács Emese Ágoston Zsófia Sztupinszki Anna-Mária Tőkés Liliána Szittya[...] József Tímár Zoltán SzállásiCharles Swanton Balázs Győrffy Janina Kulka Orvosi Hetilap Published 21 April 2013 Crick labsCharles SwantonFull details A 3-gene proliferation score (TOP-FOX-67) can re-classify histological grade-2, ER-positive breast cancers into low- and high-risk prognostic categories Authors (10) Borbála Székely Takayuki Iwamoto A Marcell Szász Yuan Qi Junji Matsuoka W Fraser Symmans Anna-Mária Tőkes Janina KulkaCharles Swanton Lajos Pusztai Breast Cancer Research and Treatment Published 1 April 2013 Crick labsCharles SwantonFull details LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development Authors (19) Liwen Lu Vitor H Teixeira ZhengQiang Yuan Trevor A Graham David Endesfelder Krishna Kolluri[...] Fiona M Watt Jeremy P George Kim B Jensen Adam Giangreco Sam M Janes Journal of Pathology Published 1 March 2013 Crick labsCharles SwantonFull details Prognostic and predictive markers in metastatic renal cell carcinoma Authors (10) Muhammad A Khattak Farrah Bakr Marcin Krzystanek Zoltan Szallasi Marco Gerlinger Claudio SantosCharles Swanton Lisa M Pickering Martin E Gore James MG Larkin Journal of Clinical Oncology Published 1 March 2013 Crick labsCharles SwantonFull details Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement Authors (12) HA Azim S Michiels F Zagouri S Delaloge M Filipits M Namer[...] WF Symmans A Thompson F André S LoiCharles Swanton Annals of Oncology Published 1 March 2013 Crick labsCharles SwantonFull details Replication stress links structural and numerical cancer chromosomal instability Authors (21) Rebecca A Burrell Sarah E McClelland David Endesfelder Petra Groth Marie-Christine Weller Nadeem Shaikh[...]Axel Behrens Thomas Helleday Jiri Bartek Ian P TomlinsonCharles Swanton Nature Published 28 February 2013 Crick labs/ facilitiesCharles SwantonAxel BehrensHigh Throughput ScreeningFull details Cancer heterogeneity: implications for targeted therapeutics Authors (3) R Fisher L PusztaiCharles Swanton British Journal of Cancer Published 19 February 2013 Crick labsCharles SwantonFull details A phase 1 study evaluating the combination of an allosteric AKT inhibitor (MK-2206) and trastuzumab in patients with HER2-positive solid tumors Authors (17) Clifford HudisCharles Swanton Yelena Y Janjigian Ray Lee Stephanie Sutherland Robert Lehman[...] Ernestina Tetteh Daniel M Sullivan Carolina Moreno Li Yan Hyo Sook Han Breast Cancer Research Published 1 January 2013 Crick labsCharles SwantonFull details Computational optimisation of targeted DNA sequencing for cancer detection Authors (5) Pierre Martinez Nicholas McGranahanNicolai Birkbak Marco GerlingerCharles Swanton Scientific Reports Published 1 January 2013 Crick labsCharles SwantonFull details Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications Authors (3) Elza C de Bruin Tiffany B TaylorCharles Swanton Genome Medicine Published 1 January 2013 Crick labsCharles SwantonFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas Authors (17) Marco Gerlinger Sergio A Quezada Karl S Peggs Andrew JS Furness Rosalie Fisher Teresa Marafioti[...] Lisa Pickering Martin Gore David L Nicol James LarkinCharles Swanton Journal of Pathology Published 1 December 2013 Crick labsCharles SwantonFull details
Cancer heterogeneity and "the struggle for existence": diagnostic and analytical challenges Authors (3) Stuart Horswell Nicholas MatthewsCharles Swanton Cancer Letters Published 1 November 2013 Crick labs/ facilitiesCharles SwantonBioinformatics and BiostatisticsAdvanced SequencingFull details
HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis Authors (14) Carrie A Adelman Rafal L LoloNicolai Birkbak Olga Murina Kenichiro Matsuzaki Zuzana Horejsi[...] Gordon Stamp Alan D'Andrea Alessandro A SartoriCharles SwantonSimon Boulton Nature Published 17 October 2013 Crick labs/ facilitiesCharles SwantonSimon BoultonExperimental HistopathologyFull details
Patupilone in patients with pretreated metastatic/locally recurrent colorectal cancer: results of the Phase II CINATRA trial Authors (13) SY Moorcraft I Chau C Peckitt D Cunningham S Rao KL Yim[...] G Stamp J Webb G Smith A GillbanksCharles Swanton Investigational New Drugs Published 1 October 2013 Crick labsCharles SwantonFull details
Acquired resistance to crizotinib from a mutation in CD74-ROS1 Authors (3) Marco Gerlinger Larry NortonCharles Swanton New England Journal of Medicine Published 19 September 2013 Crick labsCharles SwantonFull details
The causes and consequences of genetic heterogeneity in cancer evolution Authors (4) Rebecca A Burrell Nicholas McGranahan Jiri BartekCharles Swanton Nature Published 19 September 2013 Crick labsCharles SwantonFull details
Parallel evolution of tumour subclones mimics diversity between tumours Authors (11) Pierre MartinezNicolai Birkbak Marco Gerlinger Nicholas McGranahan Rebecca A BurrellAndrew Rowan Tejal Joshi Rosalie Fisher James Larkin Zoltan SzallasiCharles Swanton Journal of Pathology Published 1 August 2013 Crick labsCharles SwantonFull details
Tumour heterogeneity and immune-modulation Authors (5) Mariam Jamal-Hanjani Eirini Thanopoulou Karl S Peggs Sergio A QuezadaCharles Swanton Current Opinion in Pharmacology Published 1 August 2013 Crick labsCharles SwantonFull details
Adapting clinical paradigms to the challenges of cancer clonal evolution Authors (3) Nirupa Murugaesu Su Kit ChewCharles Swanton American Journal of Pathology Published 1 June 2013 Crick labsCharles SwantonFull details
Taxane benefit in breast cancer--a role for grade and chromosomal stability Authors (7) Roger P A'Hern Mariam Jamal-Hanjani A Marcell Szász Stephen RD Johnston Jorge S Reis-Filho Rebecca RoylanceCharles Swanton Nature Reviews Clinical Oncology Published 1 June 2013 Crick labsCharles SwantonFull details
Egyszerűsített, alacsony költségű génexpressziós teszt az emlődaganatos betegségek kimenetelének előrejelzésére rutin patológiai blokkok felhasználásával [Simplified, low-cost gene expression profiling for the prediction of outcome in breast cancer based Authors (15) A Marcell Szász Balázs Ács Emese Ágoston Zsófia Sztupinszki Anna-Mária Tőkés Liliána Szittya[...] József Tímár Zoltán SzállásiCharles Swanton Balázs Győrffy Janina Kulka Orvosi Hetilap Published 21 April 2013 Crick labsCharles SwantonFull details
A 3-gene proliferation score (TOP-FOX-67) can re-classify histological grade-2, ER-positive breast cancers into low- and high-risk prognostic categories Authors (10) Borbála Székely Takayuki Iwamoto A Marcell Szász Yuan Qi Junji Matsuoka W Fraser Symmans Anna-Mária Tőkes Janina KulkaCharles Swanton Lajos Pusztai Breast Cancer Research and Treatment Published 1 April 2013 Crick labsCharles SwantonFull details
LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development Authors (19) Liwen Lu Vitor H Teixeira ZhengQiang Yuan Trevor A Graham David Endesfelder Krishna Kolluri[...] Fiona M Watt Jeremy P George Kim B Jensen Adam Giangreco Sam M Janes Journal of Pathology Published 1 March 2013 Crick labsCharles SwantonFull details
Prognostic and predictive markers in metastatic renal cell carcinoma Authors (10) Muhammad A Khattak Farrah Bakr Marcin Krzystanek Zoltan Szallasi Marco Gerlinger Claudio SantosCharles Swanton Lisa M Pickering Martin E Gore James MG Larkin Journal of Clinical Oncology Published 1 March 2013 Crick labsCharles SwantonFull details
Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement Authors (12) HA Azim S Michiels F Zagouri S Delaloge M Filipits M Namer[...] WF Symmans A Thompson F André S LoiCharles Swanton Annals of Oncology Published 1 March 2013 Crick labsCharles SwantonFull details
Replication stress links structural and numerical cancer chromosomal instability Authors (21) Rebecca A Burrell Sarah E McClelland David Endesfelder Petra Groth Marie-Christine Weller Nadeem Shaikh[...]Axel Behrens Thomas Helleday Jiri Bartek Ian P TomlinsonCharles Swanton Nature Published 28 February 2013 Crick labs/ facilitiesCharles SwantonAxel BehrensHigh Throughput ScreeningFull details
Cancer heterogeneity: implications for targeted therapeutics Authors (3) R Fisher L PusztaiCharles Swanton British Journal of Cancer Published 19 February 2013 Crick labsCharles SwantonFull details
A phase 1 study evaluating the combination of an allosteric AKT inhibitor (MK-2206) and trastuzumab in patients with HER2-positive solid tumors Authors (17) Clifford HudisCharles Swanton Yelena Y Janjigian Ray Lee Stephanie Sutherland Robert Lehman[...] Ernestina Tetteh Daniel M Sullivan Carolina Moreno Li Yan Hyo Sook Han Breast Cancer Research Published 1 January 2013 Crick labsCharles SwantonFull details
Computational optimisation of targeted DNA sequencing for cancer detection Authors (5) Pierre Martinez Nicholas McGranahanNicolai Birkbak Marco GerlingerCharles Swanton Scientific Reports Published 1 January 2013 Crick labsCharles SwantonFull details
Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications Authors (3) Elza C de Bruin Tiffany B TaylorCharles Swanton Genome Medicine Published 1 January 2013 Crick labsCharles SwantonFull details