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Breadcrumb Charles Swanton Swanton lab Cancer Evolution and Genome Instability Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Illustration of chromosomes from a cancer cell showing large-scale alterations. Toggle to view hero caption PublicationsYear published (-)2014 (28) Facet Year publishedPublication typeJournal article (28)Primary research (13)Review (8)Commentary (6)Editorial (1) Facet Publication typeJournalAnnals of Oncology (3)Genome Biology (3)Cancer Research (2)Lancet Oncology (2)Annual Review of Genetics (1)BJU international (1)Breast Cancer Research and Treatment (1)Cancer Cell (1)Cancer Discovery (1)Clinical cancer research (1)Clinical Medicine (1)Current Biology (1)Current Opinion in Genetics & Development (1)European Urology (1)Frontiers in Oncology (1)G3 (1)Journal of Cell Science (1)Journal of Pathology (1)Molecular Oncology (1)Nature Genetics (1)PLOS Biology (1)Science (1) Facet Journal Publications Displaying 1 - 20 of 28Last updated : 20 April 2024 02:47 Epigenetic noise fuels cancer evolution Authors (2)Charles Swanton Stephan Beck Cancer Cell Published 8 December 2014 Crick labsCharles SwantonFull details Prioritizing targets for precision cancer medicine Authors (6) F Andre E Mardis M Salm JC Soria LL SiuCharles Swanton Annals of Oncology Published 1 December 2014 Crick labs/ facilitiesCharles SwantonBioinformatics and BiostatisticsFull details Spatial and temporal cancer evolution: causes and consequences of tumour diversity Authors (2) Crispin T HileyCharles Swanton Clinical Medicine Published 1 December 2014 Crick labsCharles SwantonFull details Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer Authors (13) Rebecca Roylance David Endesfelder Mariam Jamal-Hanjani Rebecca A Burrell Patricia Gorman Jil Sander[...] Andrew M Hanby Valerie Speirs Stephen RD Johnston Maik KschischoCharles Swanton Breast Cancer Research and Treatment Published 1 November 2014 Crick labsCharles SwantonFull details The genome of the chicken DT40 bursal lymphoma cell line Authors (10) János Molnár Ádám Póti Orsolya Pipek Marcin Krzystanek Nnennaya KanuCharles Swanton Gábor E Tusnády Zoltan Szallasi István Csabai Dávid Szüts G3 Published 1 November 2014 Crick labsCharles SwantonFull details Spatial and temporal diversity in genomic instability processes defines lung cancer evolution Authors (43) Elza C de Bruin Nicholas McGranahan Richard Mitter Max Salm David C Wedge Lucy Yates[...] Zoltan Szallasi Nik MatthewsAengus Stewart Peter CampbellCharles Swanton Science Published 10 October 2014 Crick labs/ facilitiesPeter Van LooCharles SwantonExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFull details Multidisciplinary urological engagement in translational renal cancer research Authors (7) Grant D Stewart David J HarrisonCharles Swanton Rebecca Lewis Judith Bliss James Larkin David L Nicol BJU international Published 1 October 2014 Crick labsCharles SwantonFull details Tumour heterogeneity and the evolution of polyclonal drug resistance Authors (2) Rebecca A BurrellCharles Swanton Molecular Oncology Published 12 September 2014 Crick labsCharles SwantonFull details Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer Authors (9) David Endesfelder Rebecca A Burrell Nnennaya Kanu Nicholas McGranahanMichael HowellPeter ParkerJulian DownwardCharles Swanton Maik Kschischo Cancer Research Published 1 September 2014 Crick labs/ facilitiesCharles SwantonPeter ParkerJulian DownwardHigh Throughput ScreeningFull details 89Zr-trastuzumab and 89Zr-bevacizumab PET to evaluate the effect of the HSP90 inhibitor NVP-AUY922 in metastatic breast cancer patients Authors (13) Sietske BM Gaykema Carolien P Schröder Joanna Vitfell-Rasmussen Sue Chua Thijs H Oude Munnink Adrienne H Brouwers[...] Cristina Fernandez-Ibarra Marjolijn N Lub-de Hooge Elisabeth GE de VriesCharles Swanton Udai Banerji Clinical cancer research Published 1 August 2014 Crick labsCharles SwantonFull details Combined inhibition of BRAF and MEK in melanoma patients Authors (2) Jeffrey R InfanteCharles Swanton Lancet Oncology Published 1 August 2014 Crick labsCharles SwantonFull details Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers Authors (13) Sakshi Gulati Pierre Martinez Tejal JoshiNicolai Birkbak Claudio R SantosAndrew Rowan[...] James Larkin Zoltan SzallasiPaul BatesCharles Swanton Marco Gerlinger European Urology Published 18 July 2014 Crick labsCharles SwantonPaul BatesFull details Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability Authors (13) Christopher J Staples Katie N Myers Ryan DD Beveridge Abhijit A Patil Anna E Howard Giancarlo Barone[...]Michael Howell Sarah MaslenMark SkehelSimon Boulton Spencer J Collis Journal of Cell Science Published 1 July 2014 Crick labs/ facilitiesCharles SwantonSimon BoultonHigh Throughput ScreeningFull details Tracking genomic cancer evolution for precision medicine: the lung TRACERx study Authors (71) Mariam Jamal-Hanjani Alan Hackshaw Yenting Ngai Jacqueline Shaw Caroline Dive Sergio Quezada[...] Ben Wilcox Maggie Wilcox Ian Woolhouse Nicholas McGranahanCharles Swanton PLOS Biology Published 1 July 2014 Crick labs/ facilitiesCharles SwantonBioinformatics and BiostatisticsAdvanced SequencingFull details Predictive performance of microarray gene signatures: impact of tumor heterogeneity and multiple mechanisms of drug resistance Authors (8) Charlotte KY Ng Britta Weigelt Roger A'Hern Francois-Clement Bidard Christophe LemetreCharles Swanton Ronglai Shen Jorge S Reis-Filho Cancer Research Published 1 June 2014 Crick labsCharles SwantonFull details Deciphering root causes of intrinsic BRAF inhibitor resistance in melanoma: ushering in a new genomics case reports feature for Annals of Oncology Authors (3)Charles Swanton F Andre E Mardis Annals of Oncology Published 1 May 2014 Crick labsCharles SwantonFull details Cancer evolution: the final frontier of precision medicine? Authors (1)Charles Swanton Annals of Oncology Published 1 March 2014 Crick labsCharles SwantonFull details Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing Authors (25) Marco Gerlinger Stuart Horswell James LarkinAndrew Rowan Max P Salm Ignacio Varela[...] David L Nicol Steven Hazell P Andrew FutrealAengus StewartCharles Swanton Nature Genetics Published 1 March 2014 Crick labs/ facilitiesCharles SwantonPaul BatesExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFull details SAFIR01: steps towards precision treatment in breast cancer Authors (1)Charles Swanton Lancet Oncology Published 1 March 2014 Crick labsCharles SwantonFull details Response to Bakhoum et al Authors (4) Rebecca A Burrell Sarah E McClelland Jiri BartekCharles Swanton Current Biology Published 17 February 2014 Crick labsCharles SwantonFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Epigenetic noise fuels cancer evolution Authors (2)Charles Swanton Stephan Beck Cancer Cell Published 8 December 2014 Crick labsCharles SwantonFull details
Prioritizing targets for precision cancer medicine Authors (6) F Andre E Mardis M Salm JC Soria LL SiuCharles Swanton Annals of Oncology Published 1 December 2014 Crick labs/ facilitiesCharles SwantonBioinformatics and BiostatisticsFull details
Spatial and temporal cancer evolution: causes and consequences of tumour diversity Authors (2) Crispin T HileyCharles Swanton Clinical Medicine Published 1 December 2014 Crick labsCharles SwantonFull details
Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer Authors (13) Rebecca Roylance David Endesfelder Mariam Jamal-Hanjani Rebecca A Burrell Patricia Gorman Jil Sander[...] Andrew M Hanby Valerie Speirs Stephen RD Johnston Maik KschischoCharles Swanton Breast Cancer Research and Treatment Published 1 November 2014 Crick labsCharles SwantonFull details
The genome of the chicken DT40 bursal lymphoma cell line Authors (10) János Molnár Ádám Póti Orsolya Pipek Marcin Krzystanek Nnennaya KanuCharles Swanton Gábor E Tusnády Zoltan Szallasi István Csabai Dávid Szüts G3 Published 1 November 2014 Crick labsCharles SwantonFull details
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution Authors (43) Elza C de Bruin Nicholas McGranahan Richard Mitter Max Salm David C Wedge Lucy Yates[...] Zoltan Szallasi Nik MatthewsAengus Stewart Peter CampbellCharles Swanton Science Published 10 October 2014 Crick labs/ facilitiesPeter Van LooCharles SwantonExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFull details
Multidisciplinary urological engagement in translational renal cancer research Authors (7) Grant D Stewart David J HarrisonCharles Swanton Rebecca Lewis Judith Bliss James Larkin David L Nicol BJU international Published 1 October 2014 Crick labsCharles SwantonFull details
Tumour heterogeneity and the evolution of polyclonal drug resistance Authors (2) Rebecca A BurrellCharles Swanton Molecular Oncology Published 12 September 2014 Crick labsCharles SwantonFull details
Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer Authors (9) David Endesfelder Rebecca A Burrell Nnennaya Kanu Nicholas McGranahanMichael HowellPeter ParkerJulian DownwardCharles Swanton Maik Kschischo Cancer Research Published 1 September 2014 Crick labs/ facilitiesCharles SwantonPeter ParkerJulian DownwardHigh Throughput ScreeningFull details
89Zr-trastuzumab and 89Zr-bevacizumab PET to evaluate the effect of the HSP90 inhibitor NVP-AUY922 in metastatic breast cancer patients Authors (13) Sietske BM Gaykema Carolien P Schröder Joanna Vitfell-Rasmussen Sue Chua Thijs H Oude Munnink Adrienne H Brouwers[...] Cristina Fernandez-Ibarra Marjolijn N Lub-de Hooge Elisabeth GE de VriesCharles Swanton Udai Banerji Clinical cancer research Published 1 August 2014 Crick labsCharles SwantonFull details
Combined inhibition of BRAF and MEK in melanoma patients Authors (2) Jeffrey R InfanteCharles Swanton Lancet Oncology Published 1 August 2014 Crick labsCharles SwantonFull details
Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers Authors (13) Sakshi Gulati Pierre Martinez Tejal JoshiNicolai Birkbak Claudio R SantosAndrew Rowan[...] James Larkin Zoltan SzallasiPaul BatesCharles Swanton Marco Gerlinger European Urology Published 18 July 2014 Crick labsCharles SwantonPaul BatesFull details
Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability Authors (13) Christopher J Staples Katie N Myers Ryan DD Beveridge Abhijit A Patil Anna E Howard Giancarlo Barone[...]Michael Howell Sarah MaslenMark SkehelSimon Boulton Spencer J Collis Journal of Cell Science Published 1 July 2014 Crick labs/ facilitiesCharles SwantonSimon BoultonHigh Throughput ScreeningFull details
Tracking genomic cancer evolution for precision medicine: the lung TRACERx study Authors (71) Mariam Jamal-Hanjani Alan Hackshaw Yenting Ngai Jacqueline Shaw Caroline Dive Sergio Quezada[...] Ben Wilcox Maggie Wilcox Ian Woolhouse Nicholas McGranahanCharles Swanton PLOS Biology Published 1 July 2014 Crick labs/ facilitiesCharles SwantonBioinformatics and BiostatisticsAdvanced SequencingFull details
Predictive performance of microarray gene signatures: impact of tumor heterogeneity and multiple mechanisms of drug resistance Authors (8) Charlotte KY Ng Britta Weigelt Roger A'Hern Francois-Clement Bidard Christophe LemetreCharles Swanton Ronglai Shen Jorge S Reis-Filho Cancer Research Published 1 June 2014 Crick labsCharles SwantonFull details
Deciphering root causes of intrinsic BRAF inhibitor resistance in melanoma: ushering in a new genomics case reports feature for Annals of Oncology Authors (3)Charles Swanton F Andre E Mardis Annals of Oncology Published 1 May 2014 Crick labsCharles SwantonFull details
Cancer evolution: the final frontier of precision medicine? Authors (1)Charles Swanton Annals of Oncology Published 1 March 2014 Crick labsCharles SwantonFull details
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing Authors (25) Marco Gerlinger Stuart Horswell James LarkinAndrew Rowan Max P Salm Ignacio Varela[...] David L Nicol Steven Hazell P Andrew FutrealAengus StewartCharles Swanton Nature Genetics Published 1 March 2014 Crick labs/ facilitiesCharles SwantonPaul BatesExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFull details
SAFIR01: steps towards precision treatment in breast cancer Authors (1)Charles Swanton Lancet Oncology Published 1 March 2014 Crick labsCharles SwantonFull details
Response to Bakhoum et al Authors (4) Rebecca A Burrell Sarah E McClelland Jiri BartekCharles Swanton Current Biology Published 17 February 2014 Crick labsCharles SwantonFull details