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Breadcrumb Charles Swanton Swanton lab Cancer Evolution and Genome Instability Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Illustration of chromosomes from a cancer cell showing large-scale alterations. Toggle to view hero caption PublicationsYear published (-)2020 (43) Facet Year publishedResearch topicsChemical Biology & High Throughput (43)Computational & Systems Biology (43)Genetics & Genomics (43)Genome Integrity & Repair (43)Human Biology & Physiology (43)Signalling & Oncogenes (43)Tumour Biology (43)Cell Biology (7)Stem Cells (6)Cell Cycle & Chromosomes (5)Infectious Disease (5)Metabolism (5)Neurosciences (5)Structural Biology & Biophysics (5)Biochemistry & Proteomics (4)Gene Expression (4)Immunology (3)Model Organisms (3)Imaging (2)Developmental Biology (1)Microfabrication & Bioengineering (1)Synthetic Biology (1) Facet Research topicsPublication typeJournal article (43)Primary research (25)Review (9)Letter (4)Commentary (2)Method (1)Obituary (1)Policy letter (1) Facet Publication typeJournalAnnals of Oncology (8)Cancer Discovery (4)Nature (4)Nature Communications (4)Nature Cancer (3)npj Breast Cancer (3)Cancer Cell (2)Cell Reports (2)Lancet (2)The Lancet (2)BMJ (1)Cell (1)Epilepsy and Behavior (1)Nature Biotechnology (1)Nature Genetics (1)Nature Medicine (1)Nature Reviews Clinical Oncology (1)Science (1)The Lancet Oncology (1) Facet Journal Publications Displaying 1 - 20 of 43Last updated : 18 April 2024 03:17 Metastasis and immune evasion from extracellular cGAMP hydrolysis Authors (41) Jun Li Mercedes A Duran Ninjit Dhanota Walid K Chatila Sarah E Bettigole John Kwon[...]Charles Swanton Alexander N Shoushtari Eileen E Parkes Benjamin Izar Samuel F Bakhoum Cancer Discovery Published 1 May 2021 Crick labsCharles SwantonFull details Angelika Amon (1967-2020) Authors (1)Charles Swanton Cancer Cell Published 14 December 2020 Crick labsCharles SwantonFull details Preexisting and de novo humoral immunity to SARS-CoV-2 in humans Authors (47)Kevin NgNikhil Faulkner Georgina H CornishAnnachiara Rosa Ruth HarveySaira Hussain[...]Steve Gamblin Laura E MccoyPeter Cherepanov Eleni NastouliGeorge Kassiotis Science Published 11 December 2020 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeWorldwide Influenza CentreStructural BiologyFlow CytometryHigh Throughput ScreeningCell ServicesFull details Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy Authors (23) Simona Balestrini Matthias J KoeppSonia Gandhi Hannah M Rickman Gee Yen Shin Catherine F Houlihan[...]Charles Swanton Crick COVID Consortium (CCC) Josemir W Sander Sanjay M Sisodiya ChAlfont keepS vulnerAble People safe (ASAP) Consortium Epilepsy and Behavior Published 1 February 2021 Crick labsCharles SwantonSonia GandhiFull details Consequences of COVID-19 for cancer care - a CRUK perspective Authors (2) Emma GreenwoodCharles Swanton Nature Reviews Clinical Oncology Published 1 January 2021 Crick labsCharles SwantonFull details Misuse of SARS-CoV-2 testing in symptomatic health-care staff in the UK – Authors' reply Authors (8) James RM Black Chris BaileyAska PrzewrockaKrijn DijkstraSonia GandhiSteve GamblinSam BarrellCharles Swanton The Lancet Published 24 October 2020 Crick labsCharles SwantonSonia GandhiSteve GamblinFull details Scientific consensus on the COVID-19 pandemic: we need to act now Authors (31) Nisreen A Alwan Rochelle Ann Burgess Simon AshworthRupert Beale Nahid Bhadelia Debby Bogaert[...] Devi SridharCharles Swanton Rochelle P Walensky Gavin Yamey Hisham Ziauddeen Lancet Published 31 October 2020 Crick labsCharles SwantonRupert BealeFull details Cancer screening, surrogates of survival, and the soma Authors (4) James DeGregori Paul Pharoah Peter SasieniCharles Swanton Cancer Cell Published 12 October 2020 Crick labsCharles SwantonFull details MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically Authors (37) Enkhtsetseg MunkhbaatarMichelle Dietzen Deepti Agrawal Martina Anton Moritz Jesinghaus Melanie Boxberg[...] Caterina Branca Mathias HeikenwalderCharles Swanton Nicholas McGranahan Philipp J Jost Nature Communications Published 10 September 2020 Crick labsCharles SwantonFull details Pervasive chromosomal instability and karyotype order in tumour evolution Authors (55)Tom WatkinsEmilia Lim Marina Petkovic Sergi ElizaldeNicolai BirkbakGareth Wilson[...]Peter Van Loo Samuel F Bakhoum Roland F Schwarz Nicholas McGranahanCharles Swanton Nature Published 5 November 2020 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonNicholas LuscombeBioinformatics and BiostatisticsScientific computingFull details Escape from nonsense-mediated decay associates with anti-tumor immunogenicity Authors (20)Kevin Litchfield James L ReadingEmilia LimHang Xu Po LiuMaise Al Bakir[...] James Larkin Sergio A Quezada Matthew D HellmannSamra TurajlicCharles Swanton Nature Communications Published 30 July 2020 Crick labs/ facilitiesSamra TurajlicCharles SwantonProteomicsFull details Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study Authors (23) Amit Sud Bethany Torr Michael E Jones John Broggio Stephen Scott Chey Loveday[...] Georgios Lyratzopoulos Ethna McFerran Mark Lawler Richard Houlston Clare Turnbull The Lancet Oncology Published 1 August 2020 Crick labsCharles SwantonFull details Immune surveillance in clinical regression of preinvasive squamous cell lung cancer Authors (38) Adam Pennycuick Vitor H Teixeira Khalid AbdulJabbar Shan E Ahmed Raza Tom Lund Ayse U Akarca[...] Teresa Marafioti Yinyin Yuan Sergio A Quezada Nicholas McGranahan Sam M Janes Cancer Discovery Published 1 October 2020 Crick labsCharles SwantonFull details Cancer Research: The lessons to learn from COVID-19 Authors (3) Chris Bailey James RM BlackCharles Swanton Cancer Discovery Published 1 September 2020 Crick labsCharles SwantonFull details The National Lung Matrix Trial of personalized therapy in lung cancer Authors (27) Gary Middleton Peter Fletcher Sanjay Popat Joshua Savage Yvonne Summers Alastair Greystoke[...] Timothy A YapTom WatkinsEmilia LimCharles Swanton Lucinda Billingham Nature Published 30 July 2020 Crick labsCharles SwantonFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Response to W.C. Taylor, and C. Fiala and E.P. Diamandis Authors (5) MC Liu GR Oxnard EA KleinCharles Swanton M Seiden Annals of Oncology Published 1 September 2020 Crick labsCharles SwantonFull details Scalable and robust SARS-CoV-2 testing in an academic center Authors (81) Jim Aitken Karen Ambrose Sam BarrellRupert Beale Ganka Bineva-Todd Dhruva Biswas[...]Sophie Ward Wai Keong WongJoshua Wright Mary Wu The Crick COVID-19 Consortium Nature Biotechnology Published 1 August 2020 Crick labs/ facilitiesAndreas WackJames TurnerCharles SwantonCaetano Reis e SousaPeter RatcliffeVenizelos PapayannopoulosGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeStructural BiologyMetabolomicsHigh Throughput ScreeningGenetic Modification ServiceFermentationBiological Research FacilityAdvanced SequencingScientific computingFull details Evidence that STK19 is not an NRAS-dependent melanoma driver Authors (11)Marta Rodriguez Martinez Thierry BoissiéreMelvin Noe GonzalezKevin Litchfield Richard MitterJane WalkerSvend KjaerSoly IsmailJulian DownwardCharles SwantonJesper Svejstrup Cell Published 11 June 2020 Crick labs/ facilitiesCharles SwantonJesper SvejstrupJulian DownwardStructural BiologyBioinformatics and BiostatisticsProteomicsCell ServicesFull details Protecting "covid protected" cancer hubs Authors (2)Charles Swanton Henry Scowcroft BMJ Published 29 May 2020 Crick labsCharles SwantonFull details Pagination Current page 1 Page 2 Page 3 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Metastasis and immune evasion from extracellular cGAMP hydrolysis Authors (41) Jun Li Mercedes A Duran Ninjit Dhanota Walid K Chatila Sarah E Bettigole John Kwon[...]Charles Swanton Alexander N Shoushtari Eileen E Parkes Benjamin Izar Samuel F Bakhoum Cancer Discovery Published 1 May 2021 Crick labsCharles SwantonFull details
Angelika Amon (1967-2020) Authors (1)Charles Swanton Cancer Cell Published 14 December 2020 Crick labsCharles SwantonFull details
Preexisting and de novo humoral immunity to SARS-CoV-2 in humans Authors (47)Kevin NgNikhil Faulkner Georgina H CornishAnnachiara Rosa Ruth HarveySaira Hussain[...]Steve Gamblin Laura E MccoyPeter Cherepanov Eleni NastouliGeorge Kassiotis Science Published 11 December 2020 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeWorldwide Influenza CentreStructural BiologyFlow CytometryHigh Throughput ScreeningCell ServicesFull details
Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy Authors (23) Simona Balestrini Matthias J KoeppSonia Gandhi Hannah M Rickman Gee Yen Shin Catherine F Houlihan[...]Charles Swanton Crick COVID Consortium (CCC) Josemir W Sander Sanjay M Sisodiya ChAlfont keepS vulnerAble People safe (ASAP) Consortium Epilepsy and Behavior Published 1 February 2021 Crick labsCharles SwantonSonia GandhiFull details
Consequences of COVID-19 for cancer care - a CRUK perspective Authors (2) Emma GreenwoodCharles Swanton Nature Reviews Clinical Oncology Published 1 January 2021 Crick labsCharles SwantonFull details
Misuse of SARS-CoV-2 testing in symptomatic health-care staff in the UK – Authors' reply Authors (8) James RM Black Chris BaileyAska PrzewrockaKrijn DijkstraSonia GandhiSteve GamblinSam BarrellCharles Swanton The Lancet Published 24 October 2020 Crick labsCharles SwantonSonia GandhiSteve GamblinFull details
Scientific consensus on the COVID-19 pandemic: we need to act now Authors (31) Nisreen A Alwan Rochelle Ann Burgess Simon AshworthRupert Beale Nahid Bhadelia Debby Bogaert[...] Devi SridharCharles Swanton Rochelle P Walensky Gavin Yamey Hisham Ziauddeen Lancet Published 31 October 2020 Crick labsCharles SwantonRupert BealeFull details
Cancer screening, surrogates of survival, and the soma Authors (4) James DeGregori Paul Pharoah Peter SasieniCharles Swanton Cancer Cell Published 12 October 2020 Crick labsCharles SwantonFull details
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically Authors (37) Enkhtsetseg MunkhbaatarMichelle Dietzen Deepti Agrawal Martina Anton Moritz Jesinghaus Melanie Boxberg[...] Caterina Branca Mathias HeikenwalderCharles Swanton Nicholas McGranahan Philipp J Jost Nature Communications Published 10 September 2020 Crick labsCharles SwantonFull details
Pervasive chromosomal instability and karyotype order in tumour evolution Authors (55)Tom WatkinsEmilia Lim Marina Petkovic Sergi ElizaldeNicolai BirkbakGareth Wilson[...]Peter Van Loo Samuel F Bakhoum Roland F Schwarz Nicholas McGranahanCharles Swanton Nature Published 5 November 2020 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonNicholas LuscombeBioinformatics and BiostatisticsScientific computingFull details
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity Authors (20)Kevin Litchfield James L ReadingEmilia LimHang Xu Po LiuMaise Al Bakir[...] James Larkin Sergio A Quezada Matthew D HellmannSamra TurajlicCharles Swanton Nature Communications Published 30 July 2020 Crick labs/ facilitiesSamra TurajlicCharles SwantonProteomicsFull details
Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study Authors (23) Amit Sud Bethany Torr Michael E Jones John Broggio Stephen Scott Chey Loveday[...] Georgios Lyratzopoulos Ethna McFerran Mark Lawler Richard Houlston Clare Turnbull The Lancet Oncology Published 1 August 2020 Crick labsCharles SwantonFull details
Immune surveillance in clinical regression of preinvasive squamous cell lung cancer Authors (38) Adam Pennycuick Vitor H Teixeira Khalid AbdulJabbar Shan E Ahmed Raza Tom Lund Ayse U Akarca[...] Teresa Marafioti Yinyin Yuan Sergio A Quezada Nicholas McGranahan Sam M Janes Cancer Discovery Published 1 October 2020 Crick labsCharles SwantonFull details
Cancer Research: The lessons to learn from COVID-19 Authors (3) Chris Bailey James RM BlackCharles Swanton Cancer Discovery Published 1 September 2020 Crick labsCharles SwantonFull details
The National Lung Matrix Trial of personalized therapy in lung cancer Authors (27) Gary Middleton Peter Fletcher Sanjay Popat Joshua Savage Yvonne Summers Alastair Greystoke[...] Timothy A YapTom WatkinsEmilia LimCharles Swanton Lucinda Billingham Nature Published 30 July 2020 Crick labsCharles SwantonFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Response to W.C. Taylor, and C. Fiala and E.P. Diamandis Authors (5) MC Liu GR Oxnard EA KleinCharles Swanton M Seiden Annals of Oncology Published 1 September 2020 Crick labsCharles SwantonFull details
Scalable and robust SARS-CoV-2 testing in an academic center Authors (81) Jim Aitken Karen Ambrose Sam BarrellRupert Beale Ganka Bineva-Todd Dhruva Biswas[...]Sophie Ward Wai Keong WongJoshua Wright Mary Wu The Crick COVID-19 Consortium Nature Biotechnology Published 1 August 2020 Crick labs/ facilitiesAndreas WackJames TurnerCharles SwantonCaetano Reis e SousaPeter RatcliffeVenizelos PapayannopoulosGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeStructural BiologyMetabolomicsHigh Throughput ScreeningGenetic Modification ServiceFermentationBiological Research FacilityAdvanced SequencingScientific computingFull details
Evidence that STK19 is not an NRAS-dependent melanoma driver Authors (11)Marta Rodriguez Martinez Thierry BoissiéreMelvin Noe GonzalezKevin Litchfield Richard MitterJane WalkerSvend KjaerSoly IsmailJulian DownwardCharles SwantonJesper Svejstrup Cell Published 11 June 2020 Crick labs/ facilitiesCharles SwantonJesper SvejstrupJulian DownwardStructural BiologyBioinformatics and BiostatisticsProteomicsCell ServicesFull details
Protecting "covid protected" cancer hubs Authors (2)Charles Swanton Henry Scowcroft BMJ Published 29 May 2020 Crick labsCharles SwantonFull details