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Breadcrumb David Balchin Balchin lab Protein Biogenesis Laboratory : Publications Lab contentLab contentIn this section Overview Members Vacancies Publications A cartoon of protein folding during translation at the ribosome. Toggle to view hero caption PublicationsCrick/Pre-CrickCrick publications (1)Pre-Crick publications (12) Facet Crick/Pre-Crick Publications Displaying 1 - 13 of 13Last updated : 18 April 2024 03:13 Calmodulin regulates protease versus co-chaperone activity of a metacaspase Authors (11) Anna Maria Eisele-Bürger Frederik Eisele Sandra Malmgren Hill Xinxin Hao Kara L Schneider Rahmi ImamogluDavid Balchin Beidong Liu F Ulrich Hartl Peter V Bozhkov Thomas Nyström Cell Reports Published 28 November 2023 Crick labsDavid BalchinFull details Recent advances in understanding catalysis of protein folding by molecular chaperones Authors (3)David Balchin Manajit Hayer-Hartl F Ulrich Hartl FEBS Letters Published 1 September 2020 Crick labsDavid BalchinFull details Efficient catalysis of protein folding by GroEL/ES of the obligate chaperonin substrate MetF Authors (5) Amit K SinghDavid Balchin Rahmi Imamoglu Manajit Hayer-Hartl F Ulrich Hartl Journal of Molecular Biology Published 27 March 2020 Crick labsDavid BalchinFull details Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein Authors (4) Rahmi ImamogluDavid Balchin Manajit Hayer-Hartl F Ulrich Hartl Nature Communications Published 17 January 2020 Crick labsDavid BalchinFull details Chaperone function of Hgh1 in the biogenesis of eukaryotic elongation factor 2 Authors (6) Leonie Mönkemeyer Courtney L KlaipsDavid Balchin Roman Körner F Ulrich Hartl Andreas Bracher Molecular Cell Published 4 April 2019 Crick labsDavid BalchinFull details Tc toxin activation requires unfolding and refolding of a β-propeller Authors (8) Christos Gatsogiannis Felipe Merino Daniel RodererDavid Balchin Evelyn Schubert Anne Kuhlee Manajit Hayer-Hartl Stefan Raunser Nature Published 8 November 2018 Crick labsDavid BalchinFull details Pathway of actin folding directed by the eukaryotic chaperonin TRiC Authors (5)David Balchin Goran Miličić Mike Strauss Manajit Hayer-Hartl F Ulrich Hartl Cell Published 6 September 2018 Crick labsDavid BalchinFull details In vivo aspects of protein folding and quality control Authors (3)David Balchin Manajit Hayer-Hartl F Ulrich Hartl Science Published 1 July 2016 Crick labsDavid BalchinFull details S-Nitrosation destabilizes glutathione transferase P1-1 Authors (3)David Balchin Stoyan H Stoychev Heini W Dirr Biochemistry Published 23 December 2013 Crick labsDavid BalchinFull details S-Nitrosation of glutathione transferase P1-1 is controlled by the conformation of a dynamic active site helix Authors (3)David Balchin Louise Wallace Heini W Dirr Journal of Biological Chemistry Published 24 May 2013 Crick labsDavid BalchinFull details Energetics of ligand binding to human glutathione transferase A1-1: Tyr-9 associated localisation of the C-terminal helix is ligand-dependent Authors (3)David Balchin Heini W Dirr Yasien Sayed Biophysical Chemistry Published 1 July 2011 Crick labsDavid BalchinFull details Stability of the domain interface contributes towards the catalytic function at the H-site of class alpha glutathione transferase A1-1 Authors (8)David Balchin Sylvia Fanucchi Ikechukwu Achilonu Roslin J Adamson Jonathan Burke Manuel Fernandes Samantha Gildenhuys Heini W Dirr Biochimica et Biophysica Acta Published 1 December 2010 Crick labsDavid BalchinFull details Class Pi glutathione transferase unfolds via a dimeric and not monomeric intermediate: functional implications for an unstable monomer Authors (6) Samantha Gildenhuys Louise A Wallace Jonathan P BurkeDavid Balchin Yasien Sayed Heini W Dirr Biochemistry Published 22 June 2010 Crick labsDavid BalchinFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Calmodulin regulates protease versus co-chaperone activity of a metacaspase Authors (11) Anna Maria Eisele-Bürger Frederik Eisele Sandra Malmgren Hill Xinxin Hao Kara L Schneider Rahmi ImamogluDavid Balchin Beidong Liu F Ulrich Hartl Peter V Bozhkov Thomas Nyström Cell Reports Published 28 November 2023 Crick labsDavid BalchinFull details
Recent advances in understanding catalysis of protein folding by molecular chaperones Authors (3)David Balchin Manajit Hayer-Hartl F Ulrich Hartl FEBS Letters Published 1 September 2020 Crick labsDavid BalchinFull details
Efficient catalysis of protein folding by GroEL/ES of the obligate chaperonin substrate MetF Authors (5) Amit K SinghDavid Balchin Rahmi Imamoglu Manajit Hayer-Hartl F Ulrich Hartl Journal of Molecular Biology Published 27 March 2020 Crick labsDavid BalchinFull details
Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein Authors (4) Rahmi ImamogluDavid Balchin Manajit Hayer-Hartl F Ulrich Hartl Nature Communications Published 17 January 2020 Crick labsDavid BalchinFull details
Chaperone function of Hgh1 in the biogenesis of eukaryotic elongation factor 2 Authors (6) Leonie Mönkemeyer Courtney L KlaipsDavid Balchin Roman Körner F Ulrich Hartl Andreas Bracher Molecular Cell Published 4 April 2019 Crick labsDavid BalchinFull details
Tc toxin activation requires unfolding and refolding of a β-propeller Authors (8) Christos Gatsogiannis Felipe Merino Daniel RodererDavid Balchin Evelyn Schubert Anne Kuhlee Manajit Hayer-Hartl Stefan Raunser Nature Published 8 November 2018 Crick labsDavid BalchinFull details
Pathway of actin folding directed by the eukaryotic chaperonin TRiC Authors (5)David Balchin Goran Miličić Mike Strauss Manajit Hayer-Hartl F Ulrich Hartl Cell Published 6 September 2018 Crick labsDavid BalchinFull details
In vivo aspects of protein folding and quality control Authors (3)David Balchin Manajit Hayer-Hartl F Ulrich Hartl Science Published 1 July 2016 Crick labsDavid BalchinFull details
S-Nitrosation destabilizes glutathione transferase P1-1 Authors (3)David Balchin Stoyan H Stoychev Heini W Dirr Biochemistry Published 23 December 2013 Crick labsDavid BalchinFull details
S-Nitrosation of glutathione transferase P1-1 is controlled by the conformation of a dynamic active site helix Authors (3)David Balchin Louise Wallace Heini W Dirr Journal of Biological Chemistry Published 24 May 2013 Crick labsDavid BalchinFull details
Energetics of ligand binding to human glutathione transferase A1-1: Tyr-9 associated localisation of the C-terminal helix is ligand-dependent Authors (3)David Balchin Heini W Dirr Yasien Sayed Biophysical Chemistry Published 1 July 2011 Crick labsDavid BalchinFull details
Stability of the domain interface contributes towards the catalytic function at the H-site of class alpha glutathione transferase A1-1 Authors (8)David Balchin Sylvia Fanucchi Ikechukwu Achilonu Roslin J Adamson Jonathan Burke Manuel Fernandes Samantha Gildenhuys Heini W Dirr Biochimica et Biophysica Acta Published 1 December 2010 Crick labsDavid BalchinFull details
Class Pi glutathione transferase unfolds via a dimeric and not monomeric intermediate: functional implications for an unstable monomer Authors (6) Samantha Gildenhuys Louise A Wallace Jonathan P BurkeDavid Balchin Yasien Sayed Heini W Dirr Biochemistry Published 22 June 2010 Crick labsDavid BalchinFull details
