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Breadcrumb Dominique Bonnet Bonnet lab Haematopoietic Stem Cell Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Members Visualisation of Leukaemic cells initiating and invading the bone marrow microenvironment Toggle to view hero caption PublicationsYear published2019 (1)2017 (1)2014 (1)2013 (1)2012 (4)2011 (1)2010 (1) Facet Year publishedResearch topicsHuman Biology & Physiology (2)Stem Cells (2)Tumour Biology (2) Facet Research topicsPublication typeJournal article (10)Primary research (10) Facet Publication typeJournal (-)Leukemia (10) Facet Journal Publications Displaying 1 - 10 of 10Last updated : 18 April 2024 03:10 Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment Authors (19) Aurélie CayeKevin Rouault-Pierre Marion Strullu Elodie Lainey Ander Abarrategi Odile Fenneteau[...] Jean-Hugues Dalle André Baruchel Christine Chomienne Hélène CavéDominique Bonnet Leukemia Published 1 June 2020 Crick labs/ facilitiesDominique BonnetFlow CytometryExperimental HistopathologyBiological Research FacilityFull details Preclinical modeling of myelodysplastic syndromes Authors (16)Kevin Rouault-Pierre SA Mian M Goulard A Abarrategi A Di Tulio AE Smith[...] C Chomienne P Fenaux C Dosquet GJ MuftiDominique Bonnet Leukemia Published 1 December 2017 Crick labs/ facilitiesDominique BonnetFlow CytometryBiological Research FacilityFull details Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo Authors (9) I Pizzitola F Anjos-Afonso K Rouault-Pierre F Lassailly S Tettamanti O Spinelli A Biondi E BiagiDominique Bonnet Leukemia Published 1 August 2014 Crick labsDominique BonnetFull details F14512, a polyamine-vectorized anti-cancer drug, currently in clinical trials exhibits a marked preclinical anti-leukemic activity Authors (13) A Kruczynski A Pillon L Créancier I Vandenberghe B Gomes V Brel[...] E Currie Y GuminskiDominique Bonnet C Bailly N Guilbaud Leukemia Published 1 January 2013 Crick labsDominique BonnetFull details Successful xenografts of AML3 samples in immunodeficient NOD/shi-SCID IL2Rγ-/- mice Authors (11) S Patel Y Zhang B Cassinat F Zassadowski N Ferré W Cuccuini JM Cayuela P FenauxDominique Bonnet C Chomienne F Louache Leukemia Published 1 November 2012 Crick labsDominique BonnetFull details Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis Authors (8) O Quintana-Bustamante S Lan-Lan Smith E Griessinger Y Reyal J Vargaftig TA Lister J FitzgibbonDominique Bonnet Leukemia Published 1 July 2012 Crick labsDominique BonnetFull details Frequency of Leukemic Initiating Cells does not depend on the xenotransplantation model used Authors (9) J Vargaftig DC Taussig E Griessinger F Anjos-Afonso TA Lister J Cavenagh H Oakervee J GribbenDominique Bonnet Leukemia Published 1 April 2012 Crick labsDominique BonnetFull details The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia Authors (21) L Willems N Chapuis A Puissant TT Maciel AS Green N Jacque[...]Dominique Bonnet C Lacombe P Mayeux D Bouscary J Tamburini Leukemia Published 1 January 2012 Crick labsDominique BonnetFull details Heterogeneous sensitivity of human Acute Myeloid Leukemia to β-catenin down-modulation Authors (8) A Gandillet S Park F Lassailly E Griessinger J Vargaftig A Filby TA ListerDominique Bonnet Leukemia Published 1 May 2011 Crick labs/ facilitiesDominique BonnetFlow CytometryFull details Effects of MSC co-injection on the reconstitution of aplastic anemia patient following hematopoietic stem cell transplantation Authors (7) BG Jaganathan V Tisato T Vulliamy I Dokal J Marsh F DazziDominique Bonnet Leukemia Published 1 October 2010 Crick labsDominique BonnetFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment Authors (19) Aurélie CayeKevin Rouault-Pierre Marion Strullu Elodie Lainey Ander Abarrategi Odile Fenneteau[...] Jean-Hugues Dalle André Baruchel Christine Chomienne Hélène CavéDominique Bonnet Leukemia Published 1 June 2020 Crick labs/ facilitiesDominique BonnetFlow CytometryExperimental HistopathologyBiological Research FacilityFull details
Preclinical modeling of myelodysplastic syndromes Authors (16)Kevin Rouault-Pierre SA Mian M Goulard A Abarrategi A Di Tulio AE Smith[...] C Chomienne P Fenaux C Dosquet GJ MuftiDominique Bonnet Leukemia Published 1 December 2017 Crick labs/ facilitiesDominique BonnetFlow CytometryBiological Research FacilityFull details
Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo Authors (9) I Pizzitola F Anjos-Afonso K Rouault-Pierre F Lassailly S Tettamanti O Spinelli A Biondi E BiagiDominique Bonnet Leukemia Published 1 August 2014 Crick labsDominique BonnetFull details
F14512, a polyamine-vectorized anti-cancer drug, currently in clinical trials exhibits a marked preclinical anti-leukemic activity Authors (13) A Kruczynski A Pillon L Créancier I Vandenberghe B Gomes V Brel[...] E Currie Y GuminskiDominique Bonnet C Bailly N Guilbaud Leukemia Published 1 January 2013 Crick labsDominique BonnetFull details
Successful xenografts of AML3 samples in immunodeficient NOD/shi-SCID IL2Rγ-/- mice Authors (11) S Patel Y Zhang B Cassinat F Zassadowski N Ferré W Cuccuini JM Cayuela P FenauxDominique Bonnet C Chomienne F Louache Leukemia Published 1 November 2012 Crick labsDominique BonnetFull details
Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis Authors (8) O Quintana-Bustamante S Lan-Lan Smith E Griessinger Y Reyal J Vargaftig TA Lister J FitzgibbonDominique Bonnet Leukemia Published 1 July 2012 Crick labsDominique BonnetFull details
Frequency of Leukemic Initiating Cells does not depend on the xenotransplantation model used Authors (9) J Vargaftig DC Taussig E Griessinger F Anjos-Afonso TA Lister J Cavenagh H Oakervee J GribbenDominique Bonnet Leukemia Published 1 April 2012 Crick labsDominique BonnetFull details
The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia Authors (21) L Willems N Chapuis A Puissant TT Maciel AS Green N Jacque[...]Dominique Bonnet C Lacombe P Mayeux D Bouscary J Tamburini Leukemia Published 1 January 2012 Crick labsDominique BonnetFull details
Heterogeneous sensitivity of human Acute Myeloid Leukemia to β-catenin down-modulation Authors (8) A Gandillet S Park F Lassailly E Griessinger J Vargaftig A Filby TA ListerDominique Bonnet Leukemia Published 1 May 2011 Crick labs/ facilitiesDominique BonnetFlow CytometryFull details
Effects of MSC co-injection on the reconstitution of aplastic anemia patient following hematopoietic stem cell transplantation Authors (7) BG Jaganathan V Tisato T Vulliamy I Dokal J Marsh F DazziDominique Bonnet Leukemia Published 1 October 2010 Crick labsDominique BonnetFull details