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Breadcrumb Dominique Bonnet Bonnet lab Haematopoietic Stem Cell Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Members Visualisation of Leukaemic cells initiating and invading the bone marrow microenvironment Toggle to view hero caption PublicationsYear published2024 (2)2023 (6)2022 (2)2021 (13)2020 (14)2019 (3)2018 (4)2017 (10)2016 (8)2015 (10)2014 (6)2013 (10)2012 (11)2011 (3)2010 (6) Facet Year publishedResearch topicsHuman Biology & Physiology (68)Stem Cells (68)Tumour Biology (68)Genetics & Genomics (22)Genome Integrity & Repair (17)Chemical Biology & High Throughput (16)Computational & Systems Biology (16)Model Organisms (14)Immunology (11)Cell Biology (7)Imaging (7)Infectious Disease (6)Cell Cycle & Chromosomes (4)Signalling & Oncogenes (4)Biochemistry & Proteomics (3)Developmental Biology (3)Gene Expression (3)Structural Biology & Biophysics (2)Metabolism (1)Microfabrication & Bioengineering (1)Neurosciences (1)Synthetic Biology (1) Facet Research topicsPublication typeJournal article (108)Primary research (80)Review (20)Method (4)Commentary (3)Editorial (1) Facet Publication typeJournalBlood (11)Leukemia (10)Haematologica (7)Nature Communications (6)British Journal of Haematology (4)Cancer Research (3)Cell Stem Cell (3)Experimental Hematology (3)Journal of Experimental Medicine (3)Stem Cell Reports (3)Blood Cancer Discovery (2)Cancer Cell (2)Cell Reports (2)HemaSphere (2)Journal of Clinical Investigation (2)Nature Reviews Cancer (2)PLOS ONE (2)Science Translational Medicine (2)Stem Cells International (2)Aging Cell (1)Analyst (1)Annals of Hematology (1)Best Practice & Research. 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- 100 of 108Last updated : 19 April 2024 02:46 DNA methylation analysis of murine hematopoietic side population cells during aging Authors (9) Oluwatosin Taiwo Gareth A Wilson Warren Emmett Tiffany MorrisDominique Bonnet Eugene Schuster Tomas Adejumo Stephan Beck Daniel J Pearce Epigenetics Published 1 October 2013 Crick labsDominique BonnetFull details Multimodal imaging reveals structural and functional heterogeneity in different bone marrow compartments: functional implications on hematopoietic stem cells Authors (5) François Lassailly Katie Foster Lourdes Lopez-Onieva Erin CurrieDominique Bonnet Blood Published 5 September 2013 Crick labs/ facilitiesDominique BonnetLight MicroscopyFull details Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation Authors (15) Farideh Miraki-Moud Fernando Anjos-Afonso Katharine A Hodby Emmanuel Griessinger Guglielmo Rosignoli Debra Lillington[...] Heather Oakervee Samir Agrawal John G GribbenDominique Bonnet David C Taussig Proceedings of the National Academy of Sciences of the United States of America Published 13 August 2013 Crick labsDominique BonnetFull details CD34- cells at the apex of the human hematopoietic stem cell hierarchy have distinctive cellular and molecular signatures Authors (6) Fernando Anjos-Afonso Erin Currie Hector G Palmer Katie E Foster David C TaussigDominique Bonnet Cell Stem Cell Published 1 August 2013 Crick labsDominique BonnetFull details Targeting of acute myeloid leukaemia by cytokine-induced killer cells redirected with a novel CD123-specific chimeric antigen receptor Authors (12) Sarah Tettamanti Virna Marin Irene Pizzitola Chiara F Magnani Greta MP Giordano Attianese Elisabetta Cribioli[...] Stefania Galimberti Angel F Lopez Andrea BiondiDominique Bonnet Ettore Biagi British Journal of Haematology Published 1 May 2013 Crick labsDominique BonnetFull details Heterogeneity of neoplastic stem cells: theoretical, functional, and clinical implications Authors (7) Peter ValentDominique Bonnet Stefan Wöhrer Michael Andreeff Mhairi Copland Christine Chomienne Connie Eaves Cancer Research Published 1 February 2013 Crick labsDominique BonnetFull details Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche Authors (4) Bithiah Grace Jaganathan Fernando Anjos-Afonso Atul KumarDominique Bonnet Journal of biomedical science Published 1 January 2013 Crick labsDominique BonnetFull details F14512, a polyamine-vectorized anti-cancer drug, currently in clinical trials exhibits a marked preclinical anti-leukemic activity Authors (13) A Kruczynski A Pillon L Créancier I Vandenberghe B Gomes V Brel[...] E Currie Y GuminskiDominique Bonnet C Bailly N Guilbaud Leukemia Published 1 January 2013 Crick labsDominique BonnetFull details CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis Authors (16) Samira Tamoutounour Sandrine Henri Hugues Lelouard Béatrice de Bovis Colin de Haar C Janneke van der Woude[...] Allan McI MowatCaetano Reis e Sousa Lionel F Poulin Bernard Malissen Martin Guilliams European Journal of Immunology Published 1 December 2012 Crick labsCaetano Reis e SousaDominique BonnetFull details Cancer stem cell definitions and terminology: the devil is in the details Authors (22) Peter ValentDominique Bonnet Ruggero De Maria Tsvee Lapidot Mhairi Copland Junia V Melo[...] Johannes Zuber Sabine Cerny-Reiterer Hans E Johnsen Michael Andreeff Connie Eaves Nature Reviews Cancer Published 1 November 2012 Crick labsDominique BonnetFull details Successful xenografts of AML3 samples in immunodeficient NOD/shi-SCID IL2Rγ-/- mice Authors (11) S Patel Y Zhang B Cassinat F Zassadowski N Ferré W Cuccuini JM Cayuela P FenauxDominique Bonnet C Chomienne F Louache Leukemia Published 1 November 2012 Crick labsDominique BonnetFull details Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms Authors (11) Elsayed E Ibrahim Roya Babaei-Jadidi Anas Saadeddin Bradley Spencer-Dene Sina Hossaini Mohammed Abuzinadah Ningning Li Wakkas Fadhil Mohammad IlyasDominique Bonnet Abdolrahman S Nateri Stem Cells Published 1 October 2012 Crick labs/ facilitiesDominique BonnetExperimental HistopathologyFull details Human mesenchymal stromal cells senesce with exogenous OCT4 Authors (2) Bithiah Grace JaganathanDominique Bonnet Cytotherapy Published 1 October 2012 Crick labsDominique BonnetFull details Engraftment defect of cytokine-cultured adult human mobilized CD34+ cells is related to reduced adhesion to bone marrow niche elements Authors (9) Konstantina Kallinikou Fernando Anjos-Afonso Michael P Blundell Stuart J Ings Michael J Watts Adrian J Thrasher David C LinchDominique Bonnet Kwee L Yong British Journal of Haematology Published 1 September 2012 Crick labsDominique BonnetFull details Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis Authors (8) O Quintana-Bustamante S Lan-Lan Smith E Griessinger Y Reyal J Vargaftig TA Lister J FitzgibbonDominique Bonnet Leukemia Published 1 July 2012 Crick labsDominique BonnetFull details DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues Authors (11) Lionel F Poulin Yasmin Reyal Heli Uronen-Hansson Barbara U Schraml David Sancho Kenneth M Murphy Ulf K Håkansson Luis Ferreira Moita William W AgaceDominique BonnetCaetano Reis e Sousa Blood Published 21 June 2012 Crick labsCaetano Reis e SousaDominique BonnetFull details Frequency of Leukemic Initiating Cells does not depend on the xenotransplantation model used Authors (9) J Vargaftig DC Taussig E Griessinger F Anjos-Afonso TA Lister J Cavenagh H Oakervee J GribbenDominique Bonnet Leukemia Published 1 April 2012 Crick labsDominique BonnetFull details Aerodynamically assisted bio-jetting of hematopoietic stem cells Authors (3) Emmanuel Griessinger Suwan N JayasingheDominique Bonnet Analyst Published 21 March 2012 Crick labsDominique BonnetFull details The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia Authors (21) L Willems N Chapuis A Puissant TT Maciel AS Green N Jacque[...]Dominique Bonnet C Lacombe P Mayeux D Bouscary J Tamburini Leukemia Published 1 January 2012 Crick labsDominique BonnetFull details Age-related changes in human hematopoietic stem/progenitor cells Authors (9) Klaudia Kuranda Jacques Vargaftig Philippe de la Rochere Christine Dosquet Dominique Charron Florence Bardin Cecile TonnelleDominique Bonnet Michele Goodhardt Aging Cell Published 1 June 2011 Crick labsDominique BonnetFull details Pagination First page First Previous page Previous Page 1 Page 2 Page 3 Page 4 Current page 5 Page 6 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on 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DNA methylation analysis of murine hematopoietic side population cells during aging Authors (9) Oluwatosin Taiwo Gareth A Wilson Warren Emmett Tiffany MorrisDominique Bonnet Eugene Schuster Tomas Adejumo Stephan Beck Daniel J Pearce Epigenetics Published 1 October 2013 Crick labsDominique BonnetFull details
Multimodal imaging reveals structural and functional heterogeneity in different bone marrow compartments: functional implications on hematopoietic stem cells Authors (5) François Lassailly Katie Foster Lourdes Lopez-Onieva Erin CurrieDominique Bonnet Blood Published 5 September 2013 Crick labs/ facilitiesDominique BonnetLight MicroscopyFull details
Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation Authors (15) Farideh Miraki-Moud Fernando Anjos-Afonso Katharine A Hodby Emmanuel Griessinger Guglielmo Rosignoli Debra Lillington[...] Heather Oakervee Samir Agrawal John G GribbenDominique Bonnet David C Taussig Proceedings of the National Academy of Sciences of the United States of America Published 13 August 2013 Crick labsDominique BonnetFull details
CD34- cells at the apex of the human hematopoietic stem cell hierarchy have distinctive cellular and molecular signatures Authors (6) Fernando Anjos-Afonso Erin Currie Hector G Palmer Katie E Foster David C TaussigDominique Bonnet Cell Stem Cell Published 1 August 2013 Crick labsDominique BonnetFull details
Targeting of acute myeloid leukaemia by cytokine-induced killer cells redirected with a novel CD123-specific chimeric antigen receptor Authors (12) Sarah Tettamanti Virna Marin Irene Pizzitola Chiara F Magnani Greta MP Giordano Attianese Elisabetta Cribioli[...] Stefania Galimberti Angel F Lopez Andrea BiondiDominique Bonnet Ettore Biagi British Journal of Haematology Published 1 May 2013 Crick labsDominique BonnetFull details
Heterogeneity of neoplastic stem cells: theoretical, functional, and clinical implications Authors (7) Peter ValentDominique Bonnet Stefan Wöhrer Michael Andreeff Mhairi Copland Christine Chomienne Connie Eaves Cancer Research Published 1 February 2013 Crick labsDominique BonnetFull details
Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche Authors (4) Bithiah Grace Jaganathan Fernando Anjos-Afonso Atul KumarDominique Bonnet Journal of biomedical science Published 1 January 2013 Crick labsDominique BonnetFull details
F14512, a polyamine-vectorized anti-cancer drug, currently in clinical trials exhibits a marked preclinical anti-leukemic activity Authors (13) A Kruczynski A Pillon L Créancier I Vandenberghe B Gomes V Brel[...] E Currie Y GuminskiDominique Bonnet C Bailly N Guilbaud Leukemia Published 1 January 2013 Crick labsDominique BonnetFull details
CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis Authors (16) Samira Tamoutounour Sandrine Henri Hugues Lelouard Béatrice de Bovis Colin de Haar C Janneke van der Woude[...] Allan McI MowatCaetano Reis e Sousa Lionel F Poulin Bernard Malissen Martin Guilliams European Journal of Immunology Published 1 December 2012 Crick labsCaetano Reis e SousaDominique BonnetFull details
Cancer stem cell definitions and terminology: the devil is in the details Authors (22) Peter ValentDominique Bonnet Ruggero De Maria Tsvee Lapidot Mhairi Copland Junia V Melo[...] Johannes Zuber Sabine Cerny-Reiterer Hans E Johnsen Michael Andreeff Connie Eaves Nature Reviews Cancer Published 1 November 2012 Crick labsDominique BonnetFull details
Successful xenografts of AML3 samples in immunodeficient NOD/shi-SCID IL2Rγ-/- mice Authors (11) S Patel Y Zhang B Cassinat F Zassadowski N Ferré W Cuccuini JM Cayuela P FenauxDominique Bonnet C Chomienne F Louache Leukemia Published 1 November 2012 Crick labsDominique BonnetFull details
Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms Authors (11) Elsayed E Ibrahim Roya Babaei-Jadidi Anas Saadeddin Bradley Spencer-Dene Sina Hossaini Mohammed Abuzinadah Ningning Li Wakkas Fadhil Mohammad IlyasDominique Bonnet Abdolrahman S Nateri Stem Cells Published 1 October 2012 Crick labs/ facilitiesDominique BonnetExperimental HistopathologyFull details
Human mesenchymal stromal cells senesce with exogenous OCT4 Authors (2) Bithiah Grace JaganathanDominique Bonnet Cytotherapy Published 1 October 2012 Crick labsDominique BonnetFull details
Engraftment defect of cytokine-cultured adult human mobilized CD34+ cells is related to reduced adhesion to bone marrow niche elements Authors (9) Konstantina Kallinikou Fernando Anjos-Afonso Michael P Blundell Stuart J Ings Michael J Watts Adrian J Thrasher David C LinchDominique Bonnet Kwee L Yong British Journal of Haematology Published 1 September 2012 Crick labsDominique BonnetFull details
Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis Authors (8) O Quintana-Bustamante S Lan-Lan Smith E Griessinger Y Reyal J Vargaftig TA Lister J FitzgibbonDominique Bonnet Leukemia Published 1 July 2012 Crick labsDominique BonnetFull details
DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues Authors (11) Lionel F Poulin Yasmin Reyal Heli Uronen-Hansson Barbara U Schraml David Sancho Kenneth M Murphy Ulf K Håkansson Luis Ferreira Moita William W AgaceDominique BonnetCaetano Reis e Sousa Blood Published 21 June 2012 Crick labsCaetano Reis e SousaDominique BonnetFull details
Frequency of Leukemic Initiating Cells does not depend on the xenotransplantation model used Authors (9) J Vargaftig DC Taussig E Griessinger F Anjos-Afonso TA Lister J Cavenagh H Oakervee J GribbenDominique Bonnet Leukemia Published 1 April 2012 Crick labsDominique BonnetFull details
Aerodynamically assisted bio-jetting of hematopoietic stem cells Authors (3) Emmanuel Griessinger Suwan N JayasingheDominique Bonnet Analyst Published 21 March 2012 Crick labsDominique BonnetFull details
The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia Authors (21) L Willems N Chapuis A Puissant TT Maciel AS Green N Jacque[...]Dominique Bonnet C Lacombe P Mayeux D Bouscary J Tamburini Leukemia Published 1 January 2012 Crick labsDominique BonnetFull details
Age-related changes in human hematopoietic stem/progenitor cells Authors (9) Klaudia Kuranda Jacques Vargaftig Philippe de la Rochere Christine Dosquet Dominique Charron Florence Bardin Cecile TonnelleDominique Bonnet Michele Goodhardt Aging Cell Published 1 June 2011 Crick labsDominique BonnetFull details