Family Zone Discover and makeExhibition entry: Best for families with primary school and early secondary school aged children
Coronavirus (COVID-19) research Crick researchers are working at the forefront of the scientific response to answer some of the most urgent questions about the SARS-CoV-2 pathogen, from how we can improve testing, to why it’s deadly in some people but causes no symptoms in others.
Coronavirus (COVID-19) response The Francis Crick Institute is working at the forefront of the scientific response to coronavirus, volunteering expertise and facilities to help tackle the COVID-19 pandemic.
Edgar Deu : Publications Lab MenuLab Menu Overview Areas of interest View more Back Dipeptidyl aminopeptidases Chemical biology Publications Breadcrumb Home Research Labs Edgar Deu Publications PublicationsYear published2020 (1)2019 (2)2018 (1)2017 (1)2016 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (6)Cell Biology (6)Computational & Systems Biology (6)Model Organisms (6)Immunology (2)Structural Biology & Biophysics (2)Chemical Biology & High Throughput (1) (-)Infectious Disease (6) Facet Research topicsPublication typeJournal article (6)Primary research (5)Review (1) Facet Publication typeJournalPLOS ONE (3)FEBS Journal (2)PLOS Pathogens (1) Facet Journal Publications Displaying 1 - 6 of 6Last updated : 04 March 2021 02:11 Novel broad-spectrum activity-based probes to profile malarial cysteine proteases Authors (8)Michele Tan Dara Davison Mateo I Sanchez Bethany M Anderson Stephen HowellBram Snijders Laura E Edgington-MitchellEdgar Deu PLOS ONE Published 10 January 2020 Crick labs/ facilitiesEdgar DeuProteomicsFull details Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening Authors (10) Mateo I Sanchez Laura E de Vries Christine Lehmann Jeong T Lee Kenny K Ang Christopher Wilson Steven Chen Michelle R Arkin Matthew BogyoEdgar Deu PLOS ONE Published 18 December 2019 Crick labsEdgar DeuFull details Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors Authors (16) Laura E de Vries Mateo I Sanchez Katarzyna Groborz Laurie Kuppens Marcin Poreba Christine Lehmann[...] Martin Horn Michael Mares Matthew Bogyo Marcin DragEdgar Deu FEBS Journal Published 1 October 2019 Crick labsEdgar DeuMike BlackmanFull details Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite Authors (7) Christine LehmannMichele Tan Laura E de Vries Ilaria Russo Mateo I Sanchez Daniel E GoldbergEdgar Deu PLOS Pathogens Published 16 May 2018 Crick labsEdgar DeuMike BlackmanFull details Proteases as antimalarial targets: strategies for genetic, chemical, and therapeutic validation Authors (1)Edgar Deu FEBS Journal Published 9 June 2017 Crick labsEdgar DeuFull details Development and application of a simple plaque assay for the human malaria parasite Plasmodium falciparum Authors (8) James A Thomas Christine R Collins Sujaan Das Fiona Hackett Arnault GraindorgeDonald BellEdgar DeuMike Blackman PLOS ONE Published 22 June 2016 Crick labs/ facilitiesEdgar DeuMike BlackmanLight MicroscopyFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Novel broad-spectrum activity-based probes to profile malarial cysteine proteases Authors (8)Michele Tan Dara Davison Mateo I Sanchez Bethany M Anderson Stephen HowellBram Snijders Laura E Edgington-MitchellEdgar Deu PLOS ONE Published 10 January 2020 Crick labs/ facilitiesEdgar DeuProteomicsFull details
Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening Authors (10) Mateo I Sanchez Laura E de Vries Christine Lehmann Jeong T Lee Kenny K Ang Christopher Wilson Steven Chen Michelle R Arkin Matthew BogyoEdgar Deu PLOS ONE Published 18 December 2019 Crick labsEdgar DeuFull details
Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors Authors (16) Laura E de Vries Mateo I Sanchez Katarzyna Groborz Laurie Kuppens Marcin Poreba Christine Lehmann[...] Martin Horn Michael Mares Matthew Bogyo Marcin DragEdgar Deu FEBS Journal Published 1 October 2019 Crick labsEdgar DeuMike BlackmanFull details
Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite Authors (7) Christine LehmannMichele Tan Laura E de Vries Ilaria Russo Mateo I Sanchez Daniel E GoldbergEdgar Deu PLOS Pathogens Published 16 May 2018 Crick labsEdgar DeuMike BlackmanFull details
Proteases as antimalarial targets: strategies for genetic, chemical, and therapeutic validation Authors (1)Edgar Deu FEBS Journal Published 9 June 2017 Crick labsEdgar DeuFull details
Development and application of a simple plaque assay for the human malaria parasite Plasmodium falciparum Authors (8) James A Thomas Christine R Collins Sujaan Das Fiona Hackett Arnault GraindorgeDonald BellEdgar DeuMike Blackman PLOS ONE Published 22 June 2016 Crick labs/ facilitiesEdgar DeuMike BlackmanLight MicroscopyFull details