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Breadcrumb Erik Sahai Sahai lab Tumour Cell Biology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Co-culture of cancer cells (darker cells) with stromal fibroblasts (lighter cells) with a signalling molecule shown in green speckles. Toggle to view hero caption PublicationsYear published2022 (1)2015 (1)2011 (2) Facet Year publishedResearch topicsCell Biology (2)Imaging (2)Model Organisms (2)Tumour Biology (2)Cell Cycle & Chromosomes (1)Chemical Biology & High Throughput (1)Computational & Systems Biology (1)Gene Expression (1)Genetics & Genomics (1)Genome Integrity & Repair (1)Human Biology & Physiology (1)Stem Cells (1) Facet Research topicsPublication typeJournal article (4)Primary research (4) Facet Publication typeJournal (-)Cancer Cell (4) Facet Journal Publications Displaying 1 - 4 of 4Last updated : 19 April 2024 02:26 Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia Authors (15)Ioannis LoukasFabrizio SimeoniMarta MilanPaolo Inglese Harshil PatelRobert Goldstone[...] Wenhao TangColin RatcliffeErik Sahai Vahid ShahrezaeiPaola Scaffidi Cancer Cell Published 9 January 2023 Crick labs/ facilitiesPaola ScaffidiErik SahaiBioinformatics and BiostatisticsStructural BiologyLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling Authors (9) Eishu Hirata Maria Romina Girotti Amaya VirosSteven Hooper Bradley Spencer-Dene Michiyuki Matsuda James Larkin Richard MaraisErik Sahai Cancer Cell Published 13 April 2015 Crick labs/ facilitiesErik SahaiExperimental HistopathologyIn Vivo ImagingBiological Research FacilityFull details ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma Authors (15) Victoria Sanz-Moreno Cedric Gaggioli Maggie Yeo Jean Albrengues Fredrik Wallberg Amaya Viros[...] James Larkin Richard Marais Guerrino MeneguzziErik Sahai Chris J Marshall Cancer Cell Published 16 August 2011 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFull details Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A Authors (8) Imanol Arozarena Berta Sanchez-Laorden Leisl Packer Cristina Hidalgo-Carcedo Robert Hayward Amaya VirosErik Sahai Richard Marais Cancer Cell Published 18 January 2011 Crick labsErik SahaiFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia Authors (15)Ioannis LoukasFabrizio SimeoniMarta MilanPaolo Inglese Harshil PatelRobert Goldstone[...] Wenhao TangColin RatcliffeErik Sahai Vahid ShahrezaeiPaola Scaffidi Cancer Cell Published 9 January 2023 Crick labs/ facilitiesPaola ScaffidiErik SahaiBioinformatics and BiostatisticsStructural BiologyLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling Authors (9) Eishu Hirata Maria Romina Girotti Amaya VirosSteven Hooper Bradley Spencer-Dene Michiyuki Matsuda James Larkin Richard MaraisErik Sahai Cancer Cell Published 13 April 2015 Crick labs/ facilitiesErik SahaiExperimental HistopathologyIn Vivo ImagingBiological Research FacilityFull details
ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma Authors (15) Victoria Sanz-Moreno Cedric Gaggioli Maggie Yeo Jean Albrengues Fredrik Wallberg Amaya Viros[...] James Larkin Richard Marais Guerrino MeneguzziErik Sahai Chris J Marshall Cancer Cell Published 16 August 2011 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFull details
Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A Authors (8) Imanol Arozarena Berta Sanchez-Laorden Leisl Packer Cristina Hidalgo-Carcedo Robert Hayward Amaya VirosErik Sahai Richard Marais Cancer Cell Published 18 January 2011 Crick labsErik SahaiFull details