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Breadcrumb Erik Sahai Sahai lab Tumour Cell Biology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Co-culture of cancer cells (darker cells) with stromal fibroblasts (lighter cells) with a signalling molecule shown in green speckles. Toggle to view hero caption PublicationsYear published2022 (1)2020 (1)2018 (1)2016 (2)2015 (1) Facet Year publishedResearch topicsCell Biology (6)Model Organisms (6)Chemical Biology & High Throughput (5)Genetics & Genomics (5)Imaging (5)Stem Cells (5)Tumour Biology (5)Computational & Systems Biology (4)Genome Integrity & Repair (4)Signalling & Oncogenes (4)Developmental Biology (3)Biochemistry & Proteomics (2)Cell Cycle & Chromosomes (2)Human Biology & Physiology (2)Immunology (1)Infectious Disease (1)Metabolism (1)Microfabrication & Bioengineering (1)Neurosciences (1)Structural Biology & Biophysics (1)Synthetic Biology (1) (-)Gene Expression (6) Facet Research topicsPublication typeJournal article (6)Primary research (6) Facet Publication typeJournalCancer Cell (1)Cell Reports (1)Cell systems (1)Development (1)Scientific Reports (1)The Lancet (1) Facet Journal Publications Displaying 1 - 6 of 6Last updated : 24 April 2024 03:20 Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia Authors (15)Ioannis LoukasFabrizio SimeoniMarta MilanPaolo Inglese Harshil PatelRobert Goldstone[...] Wenhao TangColin RatcliffeErik Sahai Vahid ShahrezaeiPaola Scaffidi Cancer Cell Published 9 January 2023 Crick labs/ facilitiesPaola ScaffidiErik SahaiBioinformatics and BiostatisticsStructural BiologyLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Quantitative analysis reveals that actin and Src-family kinases regulate nuclear YAP1 and its export Authors (8) Nil EgeAnna DowbajMing JiangMichael HowellSteven Hooper Charles FosterRob JenkinsErik Sahai Cell systems Published 27 June 2018 Crick labs/ facilitiesRichard TreismanErik SahaiHigh Throughput ScreeningFull details Integrin signalling regulates YAP and TAZ to control skin homeostasis Authors (16)Ahmed Elbediwy ZI Vincent-Mistiaen B Spencer-DeneRichard StoneStefan Boeing SK Wculek[...] H GerhardtAxel BehrensIlaria Malanchi OJ Sansom BJ Thompson Development Published 15 May 2016 Crick labs/ facilitiesBarry ThompsonErik SahaiIlaria MalanchiAxel BehrensExperimental HistopathologyBioinformatics and BiostatisticsFull details Identification of Meflin as a potential marker for mesenchymal stromal cells Authors (20) Keiko Maeda Atsushi Enomoto Akitoshi Hara Naoya Asai Takeshi Kobayashi Asuka Horinouchi[...] Yasuyuki Mizutani Osamu Watanabe Yoshiki Hirooka Hidemi Goto Masahide Takahashi Scientific Reports Published 29 February 2016 Crick labsErik SahaiFull details Mesenchymal cancer cell-stroma crosstalk promotes niche activation, epithelial reversion, and metastatic colonization Authors (11) Yaiza del Pozo MartinDanielle ParkAnassuya RamachandranLuigi Ombrato Fernando Calvo Probir Chakravarty Bradley Spencer-Dene Stefanie DerzsiCaroline HillErik SahaiIlaria Malanchi Cell Reports Published 22 December 2015 Crick labs/ facilitiesErik SahaiIlaria MalanchiCaroline HillExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia Authors (15)Ioannis LoukasFabrizio SimeoniMarta MilanPaolo Inglese Harshil PatelRobert Goldstone[...] Wenhao TangColin RatcliffeErik Sahai Vahid ShahrezaeiPaola Scaffidi Cancer Cell Published 9 January 2023 Crick labs/ facilitiesPaola ScaffidiErik SahaiBioinformatics and BiostatisticsStructural BiologyLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Quantitative analysis reveals that actin and Src-family kinases regulate nuclear YAP1 and its export Authors (8) Nil EgeAnna DowbajMing JiangMichael HowellSteven Hooper Charles FosterRob JenkinsErik Sahai Cell systems Published 27 June 2018 Crick labs/ facilitiesRichard TreismanErik SahaiHigh Throughput ScreeningFull details
Integrin signalling regulates YAP and TAZ to control skin homeostasis Authors (16)Ahmed Elbediwy ZI Vincent-Mistiaen B Spencer-DeneRichard StoneStefan Boeing SK Wculek[...] H GerhardtAxel BehrensIlaria Malanchi OJ Sansom BJ Thompson Development Published 15 May 2016 Crick labs/ facilitiesBarry ThompsonErik SahaiIlaria MalanchiAxel BehrensExperimental HistopathologyBioinformatics and BiostatisticsFull details
Identification of Meflin as a potential marker for mesenchymal stromal cells Authors (20) Keiko Maeda Atsushi Enomoto Akitoshi Hara Naoya Asai Takeshi Kobayashi Asuka Horinouchi[...] Yasuyuki Mizutani Osamu Watanabe Yoshiki Hirooka Hidemi Goto Masahide Takahashi Scientific Reports Published 29 February 2016 Crick labsErik SahaiFull details
Mesenchymal cancer cell-stroma crosstalk promotes niche activation, epithelial reversion, and metastatic colonization Authors (11) Yaiza del Pozo MartinDanielle ParkAnassuya RamachandranLuigi Ombrato Fernando Calvo Probir Chakravarty Bradley Spencer-Dene Stefanie DerzsiCaroline HillErik SahaiIlaria Malanchi Cell Reports Published 22 December 2015 Crick labs/ facilitiesErik SahaiIlaria MalanchiCaroline HillExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details