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Breadcrumb Erik Sahai Sahai lab Tumour Cell Biology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Co-culture of cancer cells (darker cells) with stromal fibroblasts (lighter cells) with a signalling molecule shown in green speckles. Toggle to view hero caption PublicationsYear published (-)2015 (14) Facet Year publishedResearch topicsCell Biology (13)Imaging (13)Model Organisms (13)Tumour Biology (13)Computational & Systems Biology (4)Chemical Biology & High Throughput (3)Developmental Biology (2)Genetics & Genomics (2)Genome Integrity & Repair (2)Immunology (2)Signalling & Oncogenes (2)Gene Expression (1)Infectious Disease (1)Microfabrication & Bioengineering (1)Stem Cells (1)Structural Biology & Biophysics (1) Facet Research topicsPublication typeJournal article (14)Primary research (10)Review (2)Commentary (1)Editorial (1) Facet Publication typeJournalCell Reports (2)Cancer Cell (1)Cancer Research (1)Cell (1)EMBO Reports (1)Journal of Cell Biology (1)Journal of Cell Science (1)Journal of the National Cancer Institute (1)Journal of the Royal Society Interface (1)Nature Cell Biology (1)Pigment Cell & Melanoma Research (1)PLoS Computational Biology (1)Trends in Cell Biology (1) Facet Journal Publications Displaying 1 - 14 of 14Last updated : 19 April 2024 03:20 Cdc42EP3/BORG2 and septin network enables mechano-transduction and the emergence of cancer-associated fibroblasts Authors (9) Fernando Calvo Romana RanftlSteven Hooper Aaron J Farrugia Emad Moeendarbary Andreas Bruckbauer Facundo Batista Guillaume CharrasErik Sahai Cell Reports Published 29 December 2015 Crick labsErik SahaiFull details Mesenchymal cancer cell-stroma crosstalk promotes niche activation, epithelial reversion, and metastatic colonization Authors (11) Yaiza del Pozo MartinDanielle ParkAnassuya RamachandranLuigi Ombrato Fernando Calvo Probir Chakravarty Bradley Spencer-Dene Stefanie DerzsiCaroline HillErik SahaiIlaria Malanchi Cell Reports Published 22 December 2015 Crick labs/ facilitiesErik SahaiIlaria MalanchiCaroline HillExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details Stochastic regulation of her1/7 gene expression is the source of noise in the zebrafish somite clock counteracted by Notch signalling Authors (5)Rob Jenkins Anja Hanisch Cristian Soza-RiedErik Sahai Julian Lewis PLoS Computational Biology Published 20 November 2015 Crick labs/ facilitiesErik SahaiBiological Research FacilityFull details Chris Marshall (1949-2015) - a personal reflection and tribute Authors (1)Erik Sahai Journal of Cell Science Published 1 November 2015 Crick labsErik SahaiFull details Reactivation of p53 by a cytoskeletal sensor to control the balance between DNA damage and tumor dissemination Authors (10) Cecilia Herraiz Fernando Calvo Pahini Pandya Gaia Cantelli Irene Rodriguez-Hernandez Jose L Orgaz NaRa Kang Tinghine ChuErik Sahai Victoria Sanz-Moreno Journal of the National Cancer Institute Published 1 January 2016 Crick labsErik SahaiFull details Chris Marshall 1949-2015 Authors (2) Alison LloydErik Sahai Nature Cell Biology Published 1 October 2015 Crick labsErik SahaiFull details Extrinsic factors can mediate resistance to BRAF inhibition in CNS melanoma metastases Authors (7) Heike Seifert Eishu Hirata Martin Gore Komel Khabra Christina Messiou James LarkinErik Sahai Pigment Cell & Melanoma Research Published 1 January 2016 Crick labsErik SahaiFull details MST kinases in development and disease Authors (2) Barry J ThompsonErik Sahai Journal of Cell Biology Published 14 September 2015 Crick labsBarry ThompsonErik SahaiFull details Cyclooxygenase-dependent tumor growth through evasion of immunity Authors (12) Santiago Zelenay Annemarthe G van der Veen Jan P Böttcher Kathryn J SnelgroveNeil Rogers Sophie E Acton[...] Maria Romina Girotti Richard Marais Sergio A QuezadaErik SahaiCaetano Reis e Sousa Cell Published 10 September 2015 Crick labs/ facilitiesErik SahaiCaetano Reis e SousaBioinformatics and BiostatisticsFull details Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis Authors (9) Chris D Madsen Jesper T Pedersen Freja A Venning Lukram Babloo Singh Emad Moeendarbary Guillaume Charras Thomas R CoxErik Sahai Janine T Erler EMBO Reports Published 1 October 2015 Crick labsErik SahaiFull details Cost-benefit analysis of the mechanisms that enable migrating cells to sustain motility upon changes in matrix environments Authors (4) Melda Tozluoglu Yanlan MaoPaul BatesErik Sahai Journal of the Royal Society Interface Published 6 May 2015 Crick labsErik SahaiPaul BatesFull details Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling Authors (9) Eishu Hirata Maria Romina Girotti Amaya VirosSteven Hooper Bradley Spencer-Dene Michiyuki Matsuda James Larkin Richard MaraisErik Sahai Cancer Cell Published 13 April 2015 Crick labs/ facilitiesErik SahaiExperimental HistopathologyIn Vivo ImagingBiological Research FacilityFull details Rho kinase inhibitors block melanoma cell migration and inhibit metastasis Authors (11) Amine SadokAfshan Mccarthy John Caldwell Ian Collins Michelle D Garrett Maggie YeoSteven HooperErik Sahai Sandra Kuemper Faraz K Mardakheh Christopher J Marshall Cancer Research Published 1 June 2015 Crick labsErik SahaiFull details An open data ecosystem for cell migration research Authors (28) Paola Masuzzo Lennart Martens Christophe AmpeKurt Anderson Joseph Barry Olivier De Wever[...] Staffan Strömblad Jason Swedlow Johannes Textor Marleen Van Troys Roman Zantl Trends in Cell Biology Published 1 February 2015 Crick labs/ facilitiesErik SahaiLight MicroscopyFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Cdc42EP3/BORG2 and septin network enables mechano-transduction and the emergence of cancer-associated fibroblasts Authors (9) Fernando Calvo Romana RanftlSteven Hooper Aaron J Farrugia Emad Moeendarbary Andreas Bruckbauer Facundo Batista Guillaume CharrasErik Sahai Cell Reports Published 29 December 2015 Crick labsErik SahaiFull details
Mesenchymal cancer cell-stroma crosstalk promotes niche activation, epithelial reversion, and metastatic colonization Authors (11) Yaiza del Pozo MartinDanielle ParkAnassuya RamachandranLuigi Ombrato Fernando Calvo Probir Chakravarty Bradley Spencer-Dene Stefanie DerzsiCaroline HillErik SahaiIlaria Malanchi Cell Reports Published 22 December 2015 Crick labs/ facilitiesErik SahaiIlaria MalanchiCaroline HillExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details
Stochastic regulation of her1/7 gene expression is the source of noise in the zebrafish somite clock counteracted by Notch signalling Authors (5)Rob Jenkins Anja Hanisch Cristian Soza-RiedErik Sahai Julian Lewis PLoS Computational Biology Published 20 November 2015 Crick labs/ facilitiesErik SahaiBiological Research FacilityFull details
Chris Marshall (1949-2015) - a personal reflection and tribute Authors (1)Erik Sahai Journal of Cell Science Published 1 November 2015 Crick labsErik SahaiFull details
Reactivation of p53 by a cytoskeletal sensor to control the balance between DNA damage and tumor dissemination Authors (10) Cecilia Herraiz Fernando Calvo Pahini Pandya Gaia Cantelli Irene Rodriguez-Hernandez Jose L Orgaz NaRa Kang Tinghine ChuErik Sahai Victoria Sanz-Moreno Journal of the National Cancer Institute Published 1 January 2016 Crick labsErik SahaiFull details
Chris Marshall 1949-2015 Authors (2) Alison LloydErik Sahai Nature Cell Biology Published 1 October 2015 Crick labsErik SahaiFull details
Extrinsic factors can mediate resistance to BRAF inhibition in CNS melanoma metastases Authors (7) Heike Seifert Eishu Hirata Martin Gore Komel Khabra Christina Messiou James LarkinErik Sahai Pigment Cell & Melanoma Research Published 1 January 2016 Crick labsErik SahaiFull details
MST kinases in development and disease Authors (2) Barry J ThompsonErik Sahai Journal of Cell Biology Published 14 September 2015 Crick labsBarry ThompsonErik SahaiFull details
Cyclooxygenase-dependent tumor growth through evasion of immunity Authors (12) Santiago Zelenay Annemarthe G van der Veen Jan P Böttcher Kathryn J SnelgroveNeil Rogers Sophie E Acton[...] Maria Romina Girotti Richard Marais Sergio A QuezadaErik SahaiCaetano Reis e Sousa Cell Published 10 September 2015 Crick labs/ facilitiesErik SahaiCaetano Reis e SousaBioinformatics and BiostatisticsFull details
Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis Authors (9) Chris D Madsen Jesper T Pedersen Freja A Venning Lukram Babloo Singh Emad Moeendarbary Guillaume Charras Thomas R CoxErik Sahai Janine T Erler EMBO Reports Published 1 October 2015 Crick labsErik SahaiFull details
Cost-benefit analysis of the mechanisms that enable migrating cells to sustain motility upon changes in matrix environments Authors (4) Melda Tozluoglu Yanlan MaoPaul BatesErik Sahai Journal of the Royal Society Interface Published 6 May 2015 Crick labsErik SahaiPaul BatesFull details
Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling Authors (9) Eishu Hirata Maria Romina Girotti Amaya VirosSteven Hooper Bradley Spencer-Dene Michiyuki Matsuda James Larkin Richard MaraisErik Sahai Cancer Cell Published 13 April 2015 Crick labs/ facilitiesErik SahaiExperimental HistopathologyIn Vivo ImagingBiological Research FacilityFull details
Rho kinase inhibitors block melanoma cell migration and inhibit metastasis Authors (11) Amine SadokAfshan Mccarthy John Caldwell Ian Collins Michelle D Garrett Maggie YeoSteven HooperErik Sahai Sandra Kuemper Faraz K Mardakheh Christopher J Marshall Cancer Research Published 1 June 2015 Crick labsErik SahaiFull details
An open data ecosystem for cell migration research Authors (28) Paola Masuzzo Lennart Martens Christophe AmpeKurt Anderson Joseph Barry Olivier De Wever[...] Staffan Strömblad Jason Swedlow Johannes Textor Marleen Van Troys Roman Zantl Trends in Cell Biology Published 1 February 2015 Crick labs/ facilitiesErik SahaiLight MicroscopyFull details