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Breadcrumb Erik Sahai Sahai lab Tumour Cell Biology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Co-culture of cancer cells (darker cells) with stromal fibroblasts (lighter cells) with a signalling molecule shown in green speckles. Toggle to view hero caption PublicationsYear published (-)2020 (9) Facet Year publishedResearch topicsCell Biology (9)Imaging (9)Model Organisms (9)Tumour Biology (9)Chemical Biology & High Throughput (2)Computational & Systems Biology (2)Genetics & Genomics (2)Genome Integrity & Repair (2)Biochemistry & Proteomics (1)Cell Cycle & Chromosomes (1)Developmental Biology (1)Gene Expression (1)Human Biology & Physiology (1)Immunology (1)Infectious Disease (1)Metabolism (1)Microfabrication & Bioengineering (1)Neurosciences (1)Signalling & Oncogenes (1)Stem Cells (1)Structural Biology & Biophysics (1)Synthetic Biology (1) Facet Research topicsPublication typeJournal article (9)Primary research (5)Review (3)Method (1) Facet Publication typeJournalNature Cell Biology (2)Cell (1)Front Cell Dev Biol (1)iScience (1)Methods in Molecular Biology (1)Nature Communications (1)Nature Reviews Cancer (1)The Lancet (1) Facet Journal Publications Displaying 1 - 9 of 9Last updated : 24 April 2024 02:34 Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer Authors (20) Oshrat Levi-Galibov Hagar Lavon Rina Wassermann-Dozorets Meirav Pevsner-Fischer Shimrit MayerEsther Wershof[...] John A PorcoErik Sahai Dror S Shouval David Kelsen Ruth Scherz-Shouval Nature Communications Published 7 December 2020 Crick labsErik SahaiFull details CAFs and cancer cells co-migration in 3D spheroid invasion assay Authors (6) Sefora Conti Takuya KatoDanielle ParkErik Sahai Xavier Trepat Anna Labernadie Methods in Molecular Biology Published 1 January 2021 Crick labsErik SahaiFull details The brain microenvironment induces DNMT1 suppression and indolence of metastatic cancer cells Authors (10) Eishu Hirata Kojiro Ishibashi Shinji Kohsaka Keiko Shinjo Shinya Kojima Yutaka Kondo Hiroyuki Mano Seiji Yano Etsuko KiyokawaErik Sahai iScience Published 25 September 2020 Crick labs/ facilitiesErik SahaiExperimental HistopathologyFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy Authors (10)Esther ArwertEmma MilfordToni Rullan Iriarte Stefanie DerzsiSteven Hooper Takuya Kato David Mansfield Alan Melcher Kevin J HarringtonErik Sahai Nature Cell Biology Published 1 July 2020 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFull details SnapShot: Cancer-associated fibroblasts Authors (3)Danielle ParkErik SahaiToni Rullan Iriarte Cell Published 16 April 2020 Crick labsErik SahaiFull details In vitro Models of Breast Cancer Metastatic Dormancy Authors (2) Marco MontagnerErik Sahai Front Cell Dev Biol Published 3 March 2020 Crick labsErik SahaiFull details Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination Authors (12) Marco Montagner Rahul BhomeSteven Hooper Probir Chakravarty Xiao Qin Jahangir Sufi[...]Colin Ratcliffe Yutaka Naito Arianna Pocaterra Christopher J TapeErik Sahai Nature Cell Biology Published 1 March 2020 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details A framework for advancing our understanding of cancer-associated fibroblasts Authors (29)Erik Sahai Igor Astsaturov Edna Cukierman David G DeNardo Mikala Egeblad Ronald M Evans[...] David A Tuveson Fiona M Watt Valerie Weaver Ashani T Weeraratna Zena Werb Nature Reviews Cancer Published 1 March 2020 Crick labsErik SahaiFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer Authors (20) Oshrat Levi-Galibov Hagar Lavon Rina Wassermann-Dozorets Meirav Pevsner-Fischer Shimrit MayerEsther Wershof[...] John A PorcoErik Sahai Dror S Shouval David Kelsen Ruth Scherz-Shouval Nature Communications Published 7 December 2020 Crick labsErik SahaiFull details
CAFs and cancer cells co-migration in 3D spheroid invasion assay Authors (6) Sefora Conti Takuya KatoDanielle ParkErik Sahai Xavier Trepat Anna Labernadie Methods in Molecular Biology Published 1 January 2021 Crick labsErik SahaiFull details
The brain microenvironment induces DNMT1 suppression and indolence of metastatic cancer cells Authors (10) Eishu Hirata Kojiro Ishibashi Shinji Kohsaka Keiko Shinjo Shinya Kojima Yutaka Kondo Hiroyuki Mano Seiji Yano Etsuko KiyokawaErik Sahai iScience Published 25 September 2020 Crick labs/ facilitiesErik SahaiExperimental HistopathologyFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy Authors (10)Esther ArwertEmma MilfordToni Rullan Iriarte Stefanie DerzsiSteven Hooper Takuya Kato David Mansfield Alan Melcher Kevin J HarringtonErik Sahai Nature Cell Biology Published 1 July 2020 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFull details
SnapShot: Cancer-associated fibroblasts Authors (3)Danielle ParkErik SahaiToni Rullan Iriarte Cell Published 16 April 2020 Crick labsErik SahaiFull details
In vitro Models of Breast Cancer Metastatic Dormancy Authors (2) Marco MontagnerErik Sahai Front Cell Dev Biol Published 3 March 2020 Crick labsErik SahaiFull details
Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination Authors (12) Marco Montagner Rahul BhomeSteven Hooper Probir Chakravarty Xiao Qin Jahangir Sufi[...]Colin Ratcliffe Yutaka Naito Arianna Pocaterra Christopher J TapeErik Sahai Nature Cell Biology Published 1 March 2020 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details
A framework for advancing our understanding of cancer-associated fibroblasts Authors (29)Erik Sahai Igor Astsaturov Edna Cukierman David G DeNardo Mikala Egeblad Ronald M Evans[...] David A Tuveson Fiona M Watt Valerie Weaver Ashani T Weeraratna Zena Werb Nature Reviews Cancer Published 1 March 2020 Crick labsErik SahaiFull details