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Breadcrumb Folkert van Werven van Werven lab Cell Fate and Gene Regulation Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies PublicationsYear published2023 (2)2022 (3)2021 (5)2020 (1)2019 (2)2018 (2)2017 (3)2016 (3)2013 (1)2012 (1)2011 (1) Facet Year publishedResearch topicsCell Biology (20)Cell Cycle & Chromosomes (20)Gene Expression (20)Genetics & Genomics (20)Model Organisms (20)Computational & Systems Biology (8)Tumour Biology (7)Chemical Biology & High Throughput (5)Biochemistry & Proteomics (4)Genome Integrity & Repair (4)Developmental Biology (2)Human Biology & Physiology (2)Immunology (2)Infectious Disease (2)Metabolism (2)Neurosciences (2)Signalling & Oncogenes (2)Stem Cells (2)Synthetic Biology (2) Facet Research topicsCrick/Pre-CrickCrick publications (20)Pre-Crick publications (3) Facet Crick/Pre-CrickPublication typeJournal article (23)Primary research (20)Review (2)Method (1) Facet Publication typeJournaleLife (4)Nature Communications (3)Cell (2)Molecular Cell (2)Cell Reports (1)Current Genetics (1)G3 (1)Genes & Development (1)Genome Biology (1)Life Science Alliance (1)Nature Methods (1)Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (1)PLOS Genetics (1)RNA (1)STAR Protocols (1)Transcription (1) Facet Journal Publications Displaying 1 - 20 of 24Last updated : 28 November 2023 02:54 The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles Authors (16)Imke Ensinck Alexander Maman Waleed S Albihlal Michelangelo Lassandro Giulia SalzanoTheodora Sideri[...]Bram SnijdersMark Skehel Ana Casañal Schraga SchwartzFolkert Van Werven eLife Published 25 July 2023 Crick labs/ facilitiesFolkert van WervenMarkus RalserProteomicsMetabolomicsBioinformatics and BiostatisticsFull details m6A-ELISA, a simple method for quantifying N6-methyladenosine from mRNA populations Authors (7)Imke EnsinckTheodora SideriMiha ModicCharlotte CapitanchikClaudia VivoriPatrick Toolan-KerrFolkert Van Werven RNA Published 1 May 2023 Crick labsFolkert van WervenFull details N6-methyladenosine (m6A) reader Pho92 is recruited co-transcriptionally and couples translation to mRNA decay to promote meiotic fitness in yeast Authors (18) Radhika A VarierTheodora SideriCharlotte CapitanchikZornitsa ManovaEnrica CalvaniAlice Rossi[...] Michiel VermeulenMarkus RalserJernej UleNicholas LuscombeFolkert Van Werven eLife Published 24 November 2022 Crick labs/ facilitiesFolkert van WervenJernej UleMarkus RalserNicholas LuscombeProteomicsMetabolomicsBioinformatics and BiostatisticsFermentationAdvanced SequencingFull details RSC and GRFs confer promoter directionality by restricting divergent noncoding transcription Authors (6)Andrew WuClaudia Vivori Harshil PatelTheodora SideriFabien MorettoFolkert Van Werven Life Science Alliance Published 1 December 2022 Crick labs/ facilitiesFolkert van WervenBioinformatics and BiostatisticsFermentationAdvanced SequencingFull details Long undecoded transcript isoform (LUTI) detection in meiotic budding yeast by direct RNA and transcript leader sequencing Authors (4) Amy TresenriderMinghao ChiaFolkert Van Werven Elçin Ünal STAR Protocols Published 18 March 2022 Crick labsFolkert van WervenFull details RNA modifications detection by comparative Nanopore direct RNA sequencing Authors (19) Adrien Leger Paulo P Amaral Luca PandolfiniCharlotte CapitanchikFederica Capraro Valentina Miano[...]Jernej Ule Tomas Fitzgerald Ewan Birney Tommaso Leonardi Tony Kouzarides Nature Communications Published 10 December 2021 Crick labsFolkert van WervenJernej UleNicholas LuscombeFull details Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution Authors (13) David Dierks Miguel Angel Garcia-Campos Anna Uzonyi Modi Safra Sarit EdelheitAlice Rossi[...] Alexander Brandis Yonatan StelzerFolkert Van Werven Ruth Scherz-Shouval Schraga Schwartz Nature Methods Published 1 September 2021 Crick labsFolkert van WervenFull details Integrated genomic analysis reveals key features of long undecoded transcript isoform-based gene repression Authors (7) Amy Tresenrider Kaitlin Morse Victoria JorgensenMinghao Chia Hanna LiaoFolkert Van Werven Elçin Ünal Molecular Cell Published 20 May 2021 Crick labsFolkert van WervenFull details Transcription levels of a noncoding RNA orchestrate opposing regulatory and cell fate outcomes in yeast Authors (6)Fabien Moretto N Ezgi WoodMinghao ChiaCai LiNicholas LuscombeFolkert Van Werven Cell Reports Published 19 January 2021 Crick labsFolkert van WervenNicholas LuscombeFull details High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts Authors (6)Minghao ChiaCai Li Sueli Marques Vicente PelechanoNicholas LuscombeFolkert Van Werven Genome Biology Published 14 January 2021 Crick labsFolkert van WervenNicholas LuscombeFull details Regulated repression governs the cell fate promoter controlling yeast meiosis Authors (2)Janis TamFolkert Van Werven Nature Communications Published 8 May 2020 Crick labsFolkert van WervenFull details Transcribe this way: Rap1 confers promoter directionality by repressing divergent transcription Authors (2)Andrew WuFolkert Van Werven Transcription Published 27 May 2019 Crick labsFolkert van WervenFull details Excessive cell growth causes cytoplasm dilution and contributes to senescence Authors (16) Gabriel E Neurohr Rachel L Terry Jette Lengefeld Megan Bonney Gregory P BrittinghamFabien Moretto[...] Stephen Buratowski Scott ManalisFolkert Van Werven Liam J Holt Angelika Amon Cell Published 29 January 2019 Crick labsFolkert van WervenFull details Repression of divergent noncoding transcription by a sequence-specific transcription factor Authors (7)Andrew Wu Harshil PatelMinghao ChiaFabien MorettoDavid FrithBram SnijdersFolkert Van Werven Molecular Cell Published 20 December 2018 Crick labs/ facilitiesFolkert van WervenProteomicsBioinformatics and BiostatisticsAdvanced SequencingFull details A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast Authors (5)Fabien Moretto N Ezgi WoodGavin Kelly Andreas DoncicFolkert Van Werven Nature Communications Published 22 February 2018 Crick labs/ facilitiesFolkert van WervenBioinformatics and BiostatisticsFull details Kinetochore inactivation by expression of a repressive mRNA Authors (9) Jingxun Chen Amy TresenriderMinghao Chia David T McSwiggen Gianpiero Spedale Victoria Jorgensen Hanna LiaoFolkert Van Werven Elçin Ünal eLife Published 14 September 2017 Crick labsFolkert van WervenFull details Transcription of a 5' extended mRNA isoform directs dynamic chromatin changes and interference of a downstream promoter Authors (7)Minghao Chia Amy Tresenrider Jingxun Chen Gianpiero Spedale Victoria Jorgensen Elçin ÜnalFolkert Van Werven eLife Published 14 September 2017 Crick labsFolkert van WervenFull details Temporal expression of a master regulator drives synchronous sporulation in budding yeast Authors (2)Minghao ChiaFolkert Van Werven G3 Published 8 November 2016 Crick labsFolkert van WervenFull details Transcription of the mating-type-regulated lncRNA IRT1 is governed by TORC1 and PKA Authors (2)Fabien MorettoFolkert Van Werven Current Genetics Published 1 May 2017 Crick labsFolkert van WervenFull details Nutrient control of yeast gametogenesis is mediated by TORC1, PKA and energy availability Authors (5) Hilla WeidbergFabien Moretto Gianpiero Spedale Angelika AmonFolkert Van Werven PLOS Genetics Published 6 June 2016 Crick labsFolkert van WervenFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles Authors (16)Imke Ensinck Alexander Maman Waleed S Albihlal Michelangelo Lassandro Giulia SalzanoTheodora Sideri[...]Bram SnijdersMark Skehel Ana Casañal Schraga SchwartzFolkert Van Werven eLife Published 25 July 2023 Crick labs/ facilitiesFolkert van WervenMarkus RalserProteomicsMetabolomicsBioinformatics and BiostatisticsFull details
m6A-ELISA, a simple method for quantifying N6-methyladenosine from mRNA populations Authors (7)Imke EnsinckTheodora SideriMiha ModicCharlotte CapitanchikClaudia VivoriPatrick Toolan-KerrFolkert Van Werven RNA Published 1 May 2023 Crick labsFolkert van WervenFull details
N6-methyladenosine (m6A) reader Pho92 is recruited co-transcriptionally and couples translation to mRNA decay to promote meiotic fitness in yeast Authors (18) Radhika A VarierTheodora SideriCharlotte CapitanchikZornitsa ManovaEnrica CalvaniAlice Rossi[...] Michiel VermeulenMarkus RalserJernej UleNicholas LuscombeFolkert Van Werven eLife Published 24 November 2022 Crick labs/ facilitiesFolkert van WervenJernej UleMarkus RalserNicholas LuscombeProteomicsMetabolomicsBioinformatics and BiostatisticsFermentationAdvanced SequencingFull details
RSC and GRFs confer promoter directionality by restricting divergent noncoding transcription Authors (6)Andrew WuClaudia Vivori Harshil PatelTheodora SideriFabien MorettoFolkert Van Werven Life Science Alliance Published 1 December 2022 Crick labs/ facilitiesFolkert van WervenBioinformatics and BiostatisticsFermentationAdvanced SequencingFull details
Long undecoded transcript isoform (LUTI) detection in meiotic budding yeast by direct RNA and transcript leader sequencing Authors (4) Amy TresenriderMinghao ChiaFolkert Van Werven Elçin Ünal STAR Protocols Published 18 March 2022 Crick labsFolkert van WervenFull details
RNA modifications detection by comparative Nanopore direct RNA sequencing Authors (19) Adrien Leger Paulo P Amaral Luca PandolfiniCharlotte CapitanchikFederica Capraro Valentina Miano[...]Jernej Ule Tomas Fitzgerald Ewan Birney Tommaso Leonardi Tony Kouzarides Nature Communications Published 10 December 2021 Crick labsFolkert van WervenJernej UleNicholas LuscombeFull details
Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution Authors (13) David Dierks Miguel Angel Garcia-Campos Anna Uzonyi Modi Safra Sarit EdelheitAlice Rossi[...] Alexander Brandis Yonatan StelzerFolkert Van Werven Ruth Scherz-Shouval Schraga Schwartz Nature Methods Published 1 September 2021 Crick labsFolkert van WervenFull details
Integrated genomic analysis reveals key features of long undecoded transcript isoform-based gene repression Authors (7) Amy Tresenrider Kaitlin Morse Victoria JorgensenMinghao Chia Hanna LiaoFolkert Van Werven Elçin Ünal Molecular Cell Published 20 May 2021 Crick labsFolkert van WervenFull details
Transcription levels of a noncoding RNA orchestrate opposing regulatory and cell fate outcomes in yeast Authors (6)Fabien Moretto N Ezgi WoodMinghao ChiaCai LiNicholas LuscombeFolkert Van Werven Cell Reports Published 19 January 2021 Crick labsFolkert van WervenNicholas LuscombeFull details
High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts Authors (6)Minghao ChiaCai Li Sueli Marques Vicente PelechanoNicholas LuscombeFolkert Van Werven Genome Biology Published 14 January 2021 Crick labsFolkert van WervenNicholas LuscombeFull details
Regulated repression governs the cell fate promoter controlling yeast meiosis Authors (2)Janis TamFolkert Van Werven Nature Communications Published 8 May 2020 Crick labsFolkert van WervenFull details
Transcribe this way: Rap1 confers promoter directionality by repressing divergent transcription Authors (2)Andrew WuFolkert Van Werven Transcription Published 27 May 2019 Crick labsFolkert van WervenFull details
Excessive cell growth causes cytoplasm dilution and contributes to senescence Authors (16) Gabriel E Neurohr Rachel L Terry Jette Lengefeld Megan Bonney Gregory P BrittinghamFabien Moretto[...] Stephen Buratowski Scott ManalisFolkert Van Werven Liam J Holt Angelika Amon Cell Published 29 January 2019 Crick labsFolkert van WervenFull details
Repression of divergent noncoding transcription by a sequence-specific transcription factor Authors (7)Andrew Wu Harshil PatelMinghao ChiaFabien MorettoDavid FrithBram SnijdersFolkert Van Werven Molecular Cell Published 20 December 2018 Crick labs/ facilitiesFolkert van WervenProteomicsBioinformatics and BiostatisticsAdvanced SequencingFull details
A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast Authors (5)Fabien Moretto N Ezgi WoodGavin Kelly Andreas DoncicFolkert Van Werven Nature Communications Published 22 February 2018 Crick labs/ facilitiesFolkert van WervenBioinformatics and BiostatisticsFull details
Kinetochore inactivation by expression of a repressive mRNA Authors (9) Jingxun Chen Amy TresenriderMinghao Chia David T McSwiggen Gianpiero Spedale Victoria Jorgensen Hanna LiaoFolkert Van Werven Elçin Ünal eLife Published 14 September 2017 Crick labsFolkert van WervenFull details
Transcription of a 5' extended mRNA isoform directs dynamic chromatin changes and interference of a downstream promoter Authors (7)Minghao Chia Amy Tresenrider Jingxun Chen Gianpiero Spedale Victoria Jorgensen Elçin ÜnalFolkert Van Werven eLife Published 14 September 2017 Crick labsFolkert van WervenFull details
Temporal expression of a master regulator drives synchronous sporulation in budding yeast Authors (2)Minghao ChiaFolkert Van Werven G3 Published 8 November 2016 Crick labsFolkert van WervenFull details
Transcription of the mating-type-regulated lncRNA IRT1 is governed by TORC1 and PKA Authors (2)Fabien MorettoFolkert Van Werven Current Genetics Published 1 May 2017 Crick labsFolkert van WervenFull details
Nutrient control of yeast gametogenesis is mediated by TORC1, PKA and energy availability Authors (5) Hilla WeidbergFabien Moretto Gianpiero Spedale Angelika AmonFolkert Van Werven PLOS Genetics Published 6 June 2016 Crick labsFolkert van WervenFull details