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Breadcrumb Francesco Saverio Tedesco Tedesco lab Stem Cells and Neuromuscular Regeneration Laboratory : Publications Lab contentLab contentIn this section Overview Members Vacancies Publications PublicationsCrick/Pre-CrickCrick publications (8)Pre-Crick publications (23) Facet Crick/Pre-Crick Publications Displaying 1 - 20 of 31Last updated : 23 March 2023 02:17 3D human induced pluripotent stem cell-derived bioengineered skeletal muscles for tissue, disease and therapy modeling Authors (14) Luca PintonMoustafa KhedrValentina Lionello Shilpita Sarcar Sara M Maffioletti Sumitava Dastidar[...] Anne Bigot John R Counsell Andreia Sofia Bernardo Peter S ZammitFrancesco Saverio Tedesco Nature Protocols Published 15 February 2023 Crick labsFrancesco Saverio TedescoFull details Mesoangioblasts at 20: From the embryonic aorta to the patient bed Authors (42) Giulio Cossu Rossana Tonlorenzi Silvia Brunelli Maurilio Sampaolesi Graziella Messina Emanuele Azzoni[...] Raffaella Scardigli Dario SirabellaFrancesco Saverio Tedesco Yvan Torrente Gonzalo Ugarte Frontiers in Genetics Published 4 January 2023 Crick labsFrancesco Saverio TedescoFull details Assessing and enhancing migration of human myogenic progenitors using directed iPS cell differentiation and advanced tissue modelling Authors (10) SungWoo Choi Giulia Ferrari Louise A Moyle Kirsty Mackinlay Naira Naouar Salma Jalal Sara Benedetti Christine Wells Francesco MuntoniFrancesco Saverio Tedesco EMBO Molecular Medicine Published 10 October 2022 Crick labs/ facilitiesFrancesco Saverio TedescoLight MicroscopyFull details Bioengineering human skeletal muscle models: Recent advances, current challenges and future perspectives Authors (5) Yunsong Jiang Tugce Torun Sara M MaffiolettiAndrea SerioFrancesco Saverio Tedesco Experimental Cell Research Published 15 July 2022 Crick labsFrancesco Saverio TedescoAndrea SerioFull details Investigating the role of dystrophin isoform deficiency in motor function in Duchenne muscular dystrophy Authors (19) Mary Chesshyre Deborah Ridout Yasumasa Hashimoto Yoko Ookubo Silvia Torelli Kate Maresh[...] Mariacristina Scoto Giovanni Baranello Adnan Manzur Yoshitsugu Aoki Francesco Muntoni Journal of Cachexia, Sarcopenia and Muscle Published 1 April 2022 Crick labsFrancesco Saverio TedescoFull details Dystrophin deficiency affects human astrocyte properties and response to damage Authors (10) Jenny Lange Olivia Gillham Reem Alkharji Simon Eaton Giulia Ferrari Monika Madej Michael FlowerFrancesco Saverio Tedesco Francesco Muntoni Patrizia Ferretti Glia Published 1 March 2022 Crick labsFrancesco Saverio TedescoFull details The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies Authors (22) Nicolas Vignier Maria Chatzifrangkeskou Luca Pinton Hugo Wioland Thibaut Marais Mégane Lemaitre[...] Guillaume Romet-Lemonne Howard J WormanFrancesco Saverio Tedesco Antoine Jégou Antoine Muchir Cell Reports Published 24 August 2021 Crick labsFrancesco Saverio TedescoFull details Advanced models of human skeletal muscle differentiation, development and disease: Three-dimensional cultures, organoids and beyond Authors (3) Salma Jalal Sumitava DastidarFrancesco Saverio Tedesco Current Opinion in Cell Biology Published 1 December 2021 Crick labsFrancesco Saverio TedescoFull details Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling Authors (22) Yasuhiro Kazuki Narumi Uno Satoshi Abe Naoyo Kajitani Kanako Kazuki Yuwna Yakura[...] Shin-ichiro Takayanagi Atsushi Kunisato Shin Kaneko Mitsuo Oshimura Kazuma Tomizuka Molecular Therapy : Nucleic Acids Published 5 March 2021 Crick labsFrancesco Saverio TedescoFull details Cellular dynamics of myogenic cell migration: molecular mechanisms and implications for skeletal muscle cell therapies Authors (3) SungWoo Choi Giulia FerrariFrancesco Saverio Tedesco EMBO Molecular Medicine Published 7 December 2020 Crick labsFrancesco Saverio TedescoFull details Generation of two genomic-integration-free DMD iPSC lines with mutations affecting all dystrophin isoforms and potentially amenable to exon-skipping Authors (3) Giulia Ferrari Francesco MuntoniFrancesco Saverio Tedesco Stem Cell Research Published 1 March 2020 Crick labsFrancesco Saverio TedescoFull details Challenging the "chromatin hypothesis" of cardiac laminopathies with LMNA mutant iPS cells Authors (2) Chiara MozzettaFrancesco Saverio Tedesco The Journal of Cell Biology Published 2 September 2019 Crick labsFrancesco Saverio TedescoFull details Pericytes in muscular dystrophies Authors (3) Louise Anne MoyleFrancesco Saverio Tedesco Sara Benedetti Advances in Experimental Medicine and Biology Published 31 May 2019 Crick labsFrancesco Saverio TedescoFull details Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform Authors (20) Glyn N Stacey Peter W Andrews Ivana Barbaric Charlotta Boiers Amit Chandra Giulio Cossu[...] Valentin P Shichkin Alison R StaceyFrancesco Saverio Tedesco Oliver Thompson Ravenska Wagey Regenerative Medicine Published 2 April 2019 Crick labsFrancesco Saverio TedescoFull details Combined Notch and PDGF signaling enhances migration and expression of stem cell markers while inducing perivascular cell features in muscle satellite cells Authors (14) Mattia Francesco Maria Gerli Louise Anne Moyle Sara Benedetti Giulia Ferrari Ekin Ucuncu Martina Ragazzi[...] Pierpaolo Ala Paolo De Coppi Shahragim Tajbakhsh Giulio CossuFrancesco Saverio Tedesco Stem Cell Reports Published 5 March 2019 Crick labsFrancesco Saverio TedescoFull details Modeling skeletal muscle laminopathies using human induced pluripotent stem cells carrying pathogenic LMNA mutations Authors (7) Heather B Steele-Stallard Luca Pinton Shilpita Sarcar Tanel Ozdemir Sara M Maffioletti Peter S ZammitFrancesco Saverio Tedesco Frontiers in Physiology Published 15 October 2018 Crick labsFrancesco Saverio TedescoFull details Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells Authors (23) Sumitava Dastidar Simon Ardui Kshitiz Singh Debanjana Majumdar Nisha Nair Yanfang Fu[...]Francesco Saverio Tedesco Joris R Vermeesch J Keith Joung Marinee K Chuah Thierry VandenDriessche Nucleic Acids Research Published 19 September 2018 Crick labsFrancesco Saverio TedescoFull details Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering Authors (22) Sara Martina Maffioletti Shilpita Sarcar Alexander BH Henderson Ingra Mannhardt Luca Pinton Louise Anne Moyle[...]Rickie Patani Peter S Zammit Dominic J Wells Thomas EschenhagenFrancesco Saverio Tedesco Cell Reports Published 17 April 2018 Crick labsFrancesco Saverio TedescoRickie PataniFull details Book review Authors (1)Francesco Saverio Tedesco Neuromuscular Disorders Published 1 March 2018 Crick labsFrancesco Saverio TedescoFull details Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy Authors (21) Sara Benedetti Narumi Uno Hidetoshi Hoshiya Martina Ragazzi Giulia Ferrari Yasuhiro Kazuki[...] George Dickson Graziella Messina Mitsuo Oshimura Giulio CossuFrancesco Saverio Tedesco EMBO Molecular Medicine Published 1 February 2018 Crick labsFrancesco Saverio TedescoFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
3D human induced pluripotent stem cell-derived bioengineered skeletal muscles for tissue, disease and therapy modeling Authors (14) Luca PintonMoustafa KhedrValentina Lionello Shilpita Sarcar Sara M Maffioletti Sumitava Dastidar[...] Anne Bigot John R Counsell Andreia Sofia Bernardo Peter S ZammitFrancesco Saverio Tedesco Nature Protocols Published 15 February 2023 Crick labsFrancesco Saverio TedescoFull details
Mesoangioblasts at 20: From the embryonic aorta to the patient bed Authors (42) Giulio Cossu Rossana Tonlorenzi Silvia Brunelli Maurilio Sampaolesi Graziella Messina Emanuele Azzoni[...] Raffaella Scardigli Dario SirabellaFrancesco Saverio Tedesco Yvan Torrente Gonzalo Ugarte Frontiers in Genetics Published 4 January 2023 Crick labsFrancesco Saverio TedescoFull details
Assessing and enhancing migration of human myogenic progenitors using directed iPS cell differentiation and advanced tissue modelling Authors (10) SungWoo Choi Giulia Ferrari Louise A Moyle Kirsty Mackinlay Naira Naouar Salma Jalal Sara Benedetti Christine Wells Francesco MuntoniFrancesco Saverio Tedesco EMBO Molecular Medicine Published 10 October 2022 Crick labs/ facilitiesFrancesco Saverio TedescoLight MicroscopyFull details
Bioengineering human skeletal muscle models: Recent advances, current challenges and future perspectives Authors (5) Yunsong Jiang Tugce Torun Sara M MaffiolettiAndrea SerioFrancesco Saverio Tedesco Experimental Cell Research Published 15 July 2022 Crick labsFrancesco Saverio TedescoAndrea SerioFull details
Investigating the role of dystrophin isoform deficiency in motor function in Duchenne muscular dystrophy Authors (19) Mary Chesshyre Deborah Ridout Yasumasa Hashimoto Yoko Ookubo Silvia Torelli Kate Maresh[...] Mariacristina Scoto Giovanni Baranello Adnan Manzur Yoshitsugu Aoki Francesco Muntoni Journal of Cachexia, Sarcopenia and Muscle Published 1 April 2022 Crick labsFrancesco Saverio TedescoFull details
Dystrophin deficiency affects human astrocyte properties and response to damage Authors (10) Jenny Lange Olivia Gillham Reem Alkharji Simon Eaton Giulia Ferrari Monika Madej Michael FlowerFrancesco Saverio Tedesco Francesco Muntoni Patrizia Ferretti Glia Published 1 March 2022 Crick labsFrancesco Saverio TedescoFull details
The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies Authors (22) Nicolas Vignier Maria Chatzifrangkeskou Luca Pinton Hugo Wioland Thibaut Marais Mégane Lemaitre[...] Guillaume Romet-Lemonne Howard J WormanFrancesco Saverio Tedesco Antoine Jégou Antoine Muchir Cell Reports Published 24 August 2021 Crick labsFrancesco Saverio TedescoFull details
Advanced models of human skeletal muscle differentiation, development and disease: Three-dimensional cultures, organoids and beyond Authors (3) Salma Jalal Sumitava DastidarFrancesco Saverio Tedesco Current Opinion in Cell Biology Published 1 December 2021 Crick labsFrancesco Saverio TedescoFull details
Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling Authors (22) Yasuhiro Kazuki Narumi Uno Satoshi Abe Naoyo Kajitani Kanako Kazuki Yuwna Yakura[...] Shin-ichiro Takayanagi Atsushi Kunisato Shin Kaneko Mitsuo Oshimura Kazuma Tomizuka Molecular Therapy : Nucleic Acids Published 5 March 2021 Crick labsFrancesco Saverio TedescoFull details
Cellular dynamics of myogenic cell migration: molecular mechanisms and implications for skeletal muscle cell therapies Authors (3) SungWoo Choi Giulia FerrariFrancesco Saverio Tedesco EMBO Molecular Medicine Published 7 December 2020 Crick labsFrancesco Saverio TedescoFull details
Generation of two genomic-integration-free DMD iPSC lines with mutations affecting all dystrophin isoforms and potentially amenable to exon-skipping Authors (3) Giulia Ferrari Francesco MuntoniFrancesco Saverio Tedesco Stem Cell Research Published 1 March 2020 Crick labsFrancesco Saverio TedescoFull details
Challenging the "chromatin hypothesis" of cardiac laminopathies with LMNA mutant iPS cells Authors (2) Chiara MozzettaFrancesco Saverio Tedesco The Journal of Cell Biology Published 2 September 2019 Crick labsFrancesco Saverio TedescoFull details
Pericytes in muscular dystrophies Authors (3) Louise Anne MoyleFrancesco Saverio Tedesco Sara Benedetti Advances in Experimental Medicine and Biology Published 31 May 2019 Crick labsFrancesco Saverio TedescoFull details
Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform Authors (20) Glyn N Stacey Peter W Andrews Ivana Barbaric Charlotta Boiers Amit Chandra Giulio Cossu[...] Valentin P Shichkin Alison R StaceyFrancesco Saverio Tedesco Oliver Thompson Ravenska Wagey Regenerative Medicine Published 2 April 2019 Crick labsFrancesco Saverio TedescoFull details
Combined Notch and PDGF signaling enhances migration and expression of stem cell markers while inducing perivascular cell features in muscle satellite cells Authors (14) Mattia Francesco Maria Gerli Louise Anne Moyle Sara Benedetti Giulia Ferrari Ekin Ucuncu Martina Ragazzi[...] Pierpaolo Ala Paolo De Coppi Shahragim Tajbakhsh Giulio CossuFrancesco Saverio Tedesco Stem Cell Reports Published 5 March 2019 Crick labsFrancesco Saverio TedescoFull details
Modeling skeletal muscle laminopathies using human induced pluripotent stem cells carrying pathogenic LMNA mutations Authors (7) Heather B Steele-Stallard Luca Pinton Shilpita Sarcar Tanel Ozdemir Sara M Maffioletti Peter S ZammitFrancesco Saverio Tedesco Frontiers in Physiology Published 15 October 2018 Crick labsFrancesco Saverio TedescoFull details
Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells Authors (23) Sumitava Dastidar Simon Ardui Kshitiz Singh Debanjana Majumdar Nisha Nair Yanfang Fu[...]Francesco Saverio Tedesco Joris R Vermeesch J Keith Joung Marinee K Chuah Thierry VandenDriessche Nucleic Acids Research Published 19 September 2018 Crick labsFrancesco Saverio TedescoFull details
Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering Authors (22) Sara Martina Maffioletti Shilpita Sarcar Alexander BH Henderson Ingra Mannhardt Luca Pinton Louise Anne Moyle[...]Rickie Patani Peter S Zammit Dominic J Wells Thomas EschenhagenFrancesco Saverio Tedesco Cell Reports Published 17 April 2018 Crick labsFrancesco Saverio TedescoRickie PataniFull details
Book review Authors (1)Francesco Saverio Tedesco Neuromuscular Disorders Published 1 March 2018 Crick labsFrancesco Saverio TedescoFull details
Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy Authors (21) Sara Benedetti Narumi Uno Hidetoshi Hoshiya Martina Ragazzi Giulia Ferrari Yasuhiro Kazuki[...] George Dickson Graziella Messina Mitsuo Oshimura Giulio CossuFrancesco Saverio Tedesco EMBO Molecular Medicine Published 1 February 2018 Crick labsFrancesco Saverio TedescoFull details