Publications

Identifying cellular signalling molecules in developmental disorders of the brain: Evidence from focal cortical dysplasia and tuberous sclerosis

Authors (17)

Yao-Feng Li
Fatma Scerif
Simon R Picker
Tom J Stone
Jessica C Pickles
Dale A Moulding
[...]
Darren Hargrave
Francois Guillemot
Simon Paine
Shireena A Yasin
Thomas S Jacques

Neuropathology and Applied Neurobiology

Published 2 April 2021

Crick labs

Francois Guillemot

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Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone in mice

Authors (28)

Naofumi Ito
M Asrafuzzaman Riyadh
Shah Adil Ishtiyaq Ahmad
Satoko Hattori
Yonehiro Kanemura
Hiroshi Kiyonari
[...]
Yoshiko Takahashi
Francois Guillemot
Tsuyoshi Miyakawa
Kazunobu Sawamoto
Kunimasa Ohta

Science Translational Medicine

Published 31 March 2021

Crick labs

Francois Guillemot

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Generation of an iPSC line (CRICKi001-A) from an individual with a germline SMARCA4 missense mutation and autism spectrum disorder

Authors (5)

Stem Cell Research

Published 1 May 2021

Crick labs/ facilities

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Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population

Authors (10)

Lachlan Harris
Piero Rigo
Thomas Stiehl
Zachary Gaber
Sophie Austin
Mar Masdeu Camara
Milly Edwards
Noelia Urbán
Anna Marciniak-Czochra
Francois Guillemot

Cell Stem Cell

Published 12 February 2021

Crick labs/ facilities

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Familial Alzheimer's disease mutations in PSEN1 lead to premature human stem cell neurogenesis

Authors (15)

Charles Arber
Christopher Lovejoy
Lachlan Harris
Nanet Willumsen
Argyro Alatza
Jackie M Casey
[...]
John Hardy
Natalie S Ryan
Nick C Fox
Tammaryn Lashley
Selina Wray

Cell Reports

Published 12 January 2021

Crick labs

Francois Guillemot

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Long-term self-renewing stem cells in the adult mouse hippocampus identified by intravital imaging

Authors (13)

Sara Bottes
Baptiste N Jaeger
Gregor-Alexander Pilz
David J Jörg
John Darby Cole
Merit Kruse
[...]
Izaskun Mallona
Fritjof Helmchen
Francois Guillemot
Benjamin D Simons
Sebastian Jessberger

Nature Neuroscience

Published 1 February 2021

Crick labs

Francois Guillemot

Full details

De novo SMARCA2 variants clustered outside the helicase domain cause a new recognizable syndrome with intellectual disability and blepharophimosis distinct from Nicolaides-Baraitser syndrome

Authors (48)

Gerarda Cappuccio
Camille Sayou
Pauline Le Tanno
Emilie Tisserant
Ange-Line Bruel
Sara El Kennani
[...]
Bekim Sadikovic
Julien Thevenon
Jérôme Govin
Antonio Vitobello
Nicola Brunetti-Pierri

Genetics in Medicine

Published 1 November 2020

Crick labs

Francois Guillemot

Full details

Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development

Authors (15)

Dong Liu
Anastasia I Kousa
Kathy E O'Neill
Paul Rouse
Martyna Popis
Alison M Farley
[...]
Mette C Jørgensen
Palle Serup
Ute Koch
Freddy Radtke
C Clare Blackburn

Development

Published 22 June 2020

Crick labs

Francois Guillemot

Full details

Quiescence of adult mammalian neural stem cells: A highly regulated rest

Authors (3)

Neuron

Published 4 December 2019

Crick labs

Francois Guillemot

Full details

Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells

Authors (9)

Isabelle Blomfield
Brenda Rocamonde
Maria del Mar Masdeu
Eskeatnaf Mulugeta
Stefania Vaga
Debbie LC van den Berg
Emmanuelle Huillard
Francois Guillemot
Noelia Urbán

eLife

Published 25 September 2019

Crick labs/ facilities

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In utero electroporation to study mouse brain development

Authors (2)

Emilie Pacary
Francois Guillemot

Methods in Molecular Biology

Published 1 January 2020

Crick labs

Francois Guillemot

Full details

Cortical neurogenesis requires Bcl6-mediated transcriptional repression of multiple self-renewal-promoting extrinsic pathways

Authors (12)

Jerome Bonnefont
Luca Tiberi
Jelle van den Ameele
Delphine Potier
Zachary Gaber
Xionghui Lin
[...]
Adèle Herpoel
Fausto D Velez Bravo
Francois Guillemot
Stein Aerts
Pierre Vanderhaeghen

Neuron

Published 25 September 2019

Crick labs/ facilities

Full details

Inflammatory arthritis as a possible feature of Coffin-Siris syndrome

Authors (7)

Sonia Melo Gomes
Cristina Dias
Ebun Omoyinmi
Sandrine Compeyrot-Lacassagne
Nigel Klein
Neil J Sebire
Paul Brogan

Pediatrics

Published 1 July 2019

Crick labs

Francois Guillemot

Full details

HES1, two programs: promoting the quiescence and proliferation of adult neural stem cells

Authors (2)

Genes and Development

Published 1 May 2019

Crick labs

Francois Guillemot

Full details

Sox2 acts in thalamic neurons to control the development of retina-thalamus-cortex connectivity

Authors (16)

Sara Mercurio
Linda Serra
Alessia Motta
Lorenzo Gesuita
Luisa Sanchez-Arrones
Francesca Inverardi
[...]
Michèle Studer
Francois Guillemot
Carolina Frassoni
Paola Bovolenta
Silvia K Nicolis

iScience

Published 26 April 2019

Crick labs

Francois Guillemot

Full details

Mapping the global chromatin connectivity network for Sox2 function in neural stem cell maintenance

Authors (23)

Jessica A Bertolini
Rebecca Favaro
Yanfen Zhu
Miriam Pagin
Chew Yee Ngan
Chee Hong Wong
[...]
Paola Bovolenta
Giulio Pavesi
Francois Guillemot
Silvia K Nicolis
Chia-Lin Wei

Cell Stem Cell

Published 7 March 2019

Crick labs

Francois Guillemot

Full details

Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration

Authors (9)

Alessandro Pristerà
Craig Blomeley
Emanuel Lopes
Sarah Threlfell
Elisa Merlini
Denis Burdakov
Stephanie Cragg
Francois Guillemot
Siew-Lan Ang

Proceedings of the National Academy of Sciences of the United States of America

Published 26 February 2019

Crick labs

Full details

CaMKIIβ regulates nucleus-centrosome coupling in locomoting neurons of the developing cerebral cortex

Authors (6)

Olivier Nicole
Donald Bell
Thierry Leste-Lasserre
Hélène Doat
Francois Guillemot
Emilie Pacary

Molecular Psychiatry

Published 6 December 2018

Crick labs/ facilities

Full details

A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis

Authors (12)

Sisu Han
Daniel J Dennis
Anjali Balakrishnan
Rajiv Dixit
Olivier Britz
Dawn Zinyk
[...]
Thomas Olender
Marjorie Brand
Francois Guillemot
Deborah Kurrasch
Carol Schuurmans

Development

Published 1 October 2018

Crick labs

Francois Guillemot

Full details

A novel role for CAMKIIβ in the regulation of cortical neuron migration: implications for neurodevelopmental disorders

Authors (6)

Olivier Nicole
Donald Bell
Thierry Leste-Lasserre
Hélène Doat
Francois Guillemot
Emilie Pacary

Molecular Psychiatry

Published 30 April 2018

Crick labs/ facilities

Full details

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Francois Guillemot : Publications

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Publications

Year published

Research topics

Publication type

Journal

Identifying cellular signalling molecules in developmental disorders of the brain: Evidence from focal cortical dysplasia and tuberous sclerosis

Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone in mice

Generation of an iPSC line (CRICKi001-A) from an individual with a germline SMARCA4 missense mutation and autism spectrum disorder

Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population

Familial Alzheimer's disease mutations in PSEN1 lead to premature human stem cell neurogenesis

Long-term self-renewing stem cells in the adult mouse hippocampus identified by intravital imaging

De novo SMARCA2 variants clustered outside the helicase domain cause a new recognizable syndrome with intellectual disability and blepharophimosis distinct from Nicolaides-Baraitser syndrome

Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development

Quiescence of adult mammalian neural stem cells: A highly regulated rest

Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells

In utero electroporation to study mouse brain development

Cortical neurogenesis requires Bcl6-mediated transcriptional repression of multiple self-renewal-promoting extrinsic pathways

Inflammatory arthritis as a possible feature of Coffin-Siris syndrome

HES1, two programs: promoting the quiescence and proliferation of adult neural stem cells

Sox2 acts in thalamic neurons to control the development of retina-thalamus-cortex connectivity

Mapping the global chromatin connectivity network for Sox2 function in neural stem cell maintenance

Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration

CaMKIIβ regulates nucleus-centrosome coupling in locomoting neurons of the developing cerebral cortex

A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis

A novel role for CAMKIIβ in the regulation of cortical neuron migration: implications for neurodevelopmental disorders

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