Publications

Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors

Authors (6)

Chromosoma

Published 1 June 2023

Crick labs/ facilities

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A replication fork determinant for the establishment of sister chromatid cohesion

Authors (5)

Cell

Published 16 February 2023

Crick labs/ facilities

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Functional crosstalk between the cohesin loader and chromatin remodelers

Authors (6)

Nature Communications

Published 13 December 2022

Crick labs/ facilities

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Chromosome arm length, and a species-specific determinant, define chromosome arm width

Authors (7)

Yasutaka Kakui
Christopher Barrington
Yoshiharu Kusano
Rahul Thadani
Todd Fallesen
Toru Hirota
Frank Uhlmann

Cell Reports

Published 6 December 2022

Crick labs/ facilities

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Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Authors (9)

Mark Mattingly
Chris Seidel
Sofia Munoz-Felix
Yan Hao
Ying Zhang
Zhihui Wen
Laurence Florens
Frank Uhlmann
Jennifer L Gerton

Current Biology

Published 11 July 2022

Crick labs

Frank Uhlmann

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SMC complexes: Lifting the lid on loop extrusion

Authors (2)

Current Opinion in Cell Biology

Published 1 February 2022

Crick labs

Frank Uhlmann

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A Brownian ratchet model for DNA loop extrusion by the cohesin complex

Authors (5)

eLife

Published 26 July 2021

Crick labs/ facilities

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Analysis of cell cycle progression in the budding yeast S. cerevisiae

Authors (2)

Methods in Molecular Biology

Published 1 January 2021

Crick labs

Frank Uhlmann

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Budding yeast relies on G1 cyclin specificity to couple cell cycle progression with morphogenetic development

Authors (6)

Deniz Pirincci Ercan
Florine Chrétien
Probir Chakravarty
Helen R Flynn
Bram Snijders
Frank Uhlmann

Science advances

Published 4 June 2021

Crick labs/ facilities

Full details

A role for condensin in mediating transcriptional adaptation to environmental stimuli

Authors (4)

Life Science Alliance

Published 1 July 2021

Crick labs/ facilities

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Structural characterisation of the Chaetomium thermophilum Chl1 helicase

Authors (8)

PLOS ONE

Published 10 May 2021

Crick labs/ facilities

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Bridging-induced phase separation induced by cohesin SMC protein complexes

Authors (12)

Je-Kyung Ryu
Celine Bouchoux
Hon Liu
Eugene Kim
Masashi Minamino
Ralph de Groot
[...]
Andrea Bonato
Davide Marenduzzo
Davide Michieletto
Frank Uhlmann
Cees Dekker

Science advances

Published 10 February 2021

Crick labs

Frank Uhlmann

Full details

Comparison of loop extrusion and diffusion capture as mitotic chromosome formation pathways in fission yeast

Authors (7)

Tereza Clarence
Xiao Fu
Yasutaka Kakui
Bhavin S Khatri
Christopher Barrington
Paul Bates
Frank Uhlmann

Nucleic Acids Research

Published 22 February 2021

Crick labs/ facilities

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Fission yeast condensin contributes to interphase chromatin organization and prevents transcription-coupled DNA damage

Authors (8)

Genome Biology

Published 5 November 2020

Crick labs/ facilities

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CSynth: an interactive modelling and visualization tool for 3D chromatin structure

Authors (8)

Stephen Todd
Peter Todd
Simon J McGowan
James R Hughes
Yasutaka Kakui
Frederic Fol Leymarie
William Latham
Stephen Taylor

Bioinformatics

Published 1 April 2021

Crick labs

Frank Uhlmann

Full details

A structure-based mechanism for DNA entry into the cohesin ring

Authors (14)

Torahiko Higashi
Patrik Eickhoff
Joana S Sousa
Julia Locke
Andrea Nans
Helen R Flynn
[...]
Zhuo A Chen
Francis J O’Reilly
Juri Rappsilber
Alessandro Costa
Frank Uhlmann

Molecular Cell

Published 17 September 2020

Crick labs/ facilities

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Assessing budding yeast phosphoproteome dynamics in a time-resolved manner using TMT10plex mass tag labeling

Authors (5)

STAR Protocols

Published 19 June 2020

Crick labs/ facilities

Full details

Conserved roles of chromatin remodellers in cohesin loading onto chromatin

Authors (3)

Current Genetics

Published 1 October 2020

Crick labs

Frank Uhlmann

Full details

Division of labor between PCNA loaders in DNA replication and sister chromatid cohesion establishment

Authors (6)

Hon Liu
Celine Bouchoux
Mélanie Panarotto
Yasutaka Kakui
Harshil Patel
Frank Uhlmann

Molecular Cell

Published 21 May 2020

Crick labs/ facilities

Full details

Cdc14 and PP2A phosphatases cooperate to shape phosphoproteome dynamics during mitotic exit

Authors (6)

Cell Reports

Published 12 November 2019

Crick labs/ facilities

Full details

Research case studies

Vacancies

Cut + Paste exhibition

From local to global: preparing for the next pandemic

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Chromosome Segregation Laboratory
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Publications

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Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors

A replication fork determinant for the establishment of sister chromatid cohesion

Functional crosstalk between the cohesin loader and chromatin remodelers

Chromosome arm length, and a species-specific determinant, define chromosome arm width

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

SMC complexes: Lifting the lid on loop extrusion

A Brownian ratchet model for DNA loop extrusion by the cohesin complex

Analysis of cell cycle progression in the budding yeast S. cerevisiae

Budding yeast relies on G1 cyclin specificity to couple cell cycle progression with morphogenetic development

A role for condensin in mediating transcriptional adaptation to environmental stimuli

Structural characterisation of the Chaetomium thermophilum Chl1 helicase

Bridging-induced phase separation induced by cohesin SMC protein complexes

Comparison of loop extrusion and diffusion capture as mitotic chromosome formation pathways in fission yeast

Fission yeast condensin contributes to interphase chromatin organization and prevents transcription-coupled DNA damage

CSynth: an interactive modelling and visualization tool for 3D chromatin structure

A structure-based mechanism for DNA entry into the cohesin ring

Assessing budding yeast phosphoproteome dynamics in a time-resolved manner using TMT10plex mass tag labeling

Conserved roles of chromatin remodellers in cohesin loading onto chromatin

Division of labor between PCNA loaders in DNA replication and sister chromatid cohesion establishment

Cdc14 and PP2A phosphatases cooperate to shape phosphoproteome dynamics during mitotic exit

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From local to global: preparing for the next pandemic

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