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Breadcrumb George Kassiotis Kassiotis lab Retroviral Immunology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Numerous retroviral particles (pseudocoloured) endogenously produced by lymphoma cells in an immune-deficient mouse. Toggle to view hero caption PublicationsYear published2023 (5)2022 (2)2021 (1)2020 (1) Facet Year publishedResearch topicsComputational & Systems Biology (9)Genetics & Genomics (9)Immunology (9)Model Organisms (9)Chemical Biology & High Throughput (8)Genome Integrity & Repair (8)Human Biology & Physiology (8)Tumour Biology (8)Cell Biology (6)Signalling & Oncogenes (6)Stem Cells (6)Cell Cycle & Chromosomes (5)Infectious Disease (3)Biochemistry & Proteomics (2)Developmental Biology (2)Imaging (2)Metabolism (2)Neurosciences (2)Structural Biology & Biophysics (2)Synthetic Biology (2)Microfabrication & Bioengineering (1) (-)Gene Expression (9) Facet Research topicsPublication typeJournal article (9)Primary research (8)Review (1) Facet Publication typeJournalNature (4)Cancer Cell (1)Cancer Research (1)NAR Cancer (1)Science (1)The Lancet (1) Facet Journal Publications Displaying 1 - 9 of 9Last updated : 23 April 2024 03:35 The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes Authors (11)Anastasiya KazachenkaJane LoongJan AttigGeorge YoungPiyali Ganguli Ginny Devonshire Nicola Grehan The OCCAMS ConsortiumFrancesca Ciccarelli Rebecca C FitzgeraldGeorge Kassiotis NAR Cancer Published 1 September 2023 Crick labs/ facilitiesGeorge KassiotisFrancesca CiccarelliBioinformatics and BiostatisticsScientific computingCell ServicesAdvanced SequencingFull details Innate virus-sensing pathways in B cell systemic autoimmunity Authors (3)Carola Vinuesa Amalie GrenovGeorge Kassiotis Science Published 5 May 2023 Crick labsCarola VinuesaGeorge KassiotisFull details Antibodies against endogenous retroviruses promote lung cancer immunotherapy Authors (51)Kevin NgJesse BoumelhaKatey EnfieldJorge Almagro Hongui Cha Oriol Pich[...] Se-Hoon LeeSamra TurajlicCharles SwantonJulian DownwardGeorge Kassiotis Nature Published 20 April 2023 Crick labs/ facilitiesRobert J WilkinsonPeter Van LooSamra TurajlicCharles SwantonGeorge KassiotisJulian DownwardAxel BehrensFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingProteomicsLight MicroscopyCell ServicesBiological Research FacilityFull details Genomic-transcriptomic evolution in lung cancer and metastasis Authors (47) Carlos Martínez-Ruiz James RM Black Clare Puttick Mark S HillJonas DemeulemeesterElizabeth Larose Cadieux[...] Peter Van Loo Mariam Jamal-Hanjani TRACERx Consortium Charles Swanton Nicholas McGranahan Nature Published 20 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisJulian DownwardFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Lung adenocarcinoma promotion by air pollutants Authors (72)William HillEmilia LimClare Weeden Claudia Lee Marcellus Augustine Kezhong Chen[...] Kevin Litchfield TRACERx Consortium James DeGregori Mariam Jamal-HanjaniCharles Swanton Nature Published 6 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonIlaria MalanchiGeorge KassiotisJulian DownwardFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingLight MicroscopyBiological Research FacilityFull details An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations Authors (26)Jesse BoumelhaSophie de Carne Emily K Law Pablo Romero-Clavijo Matthew A CoelhoKevin Ng[...]George KassiotisMiriam Molina ArcasCharles Swanton Reuben HarrisJulian Downward Cancer Research Published 1 October 2022 Crick labs/ facilitiesCharles SwantonGeorge KassiotisJulian DownwardExperimental HistopathologyBioinformatics and BiostatisticsScientific computingFlow CytometryCell ServicesBiological Research FacilityFull details GREM1 is required to maintain cellular heterogeneity in pancreatic cancer Authors (21) Linxiang Lan Theodore Evan Huafu Li Aasia Hussain E Josue Ruiz May Zaw Thin[...]Emma Nye Yulong He Changhua Zhang Anguraj SadanandamAxel Behrens Nature Published 7 July 2022 Crick labs/ facilitiesIlaria MalanchiGeorge KassiotisAxel BehrensExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer Authors (65)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary Wu Andreas M Schmitt[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE consortium Cancer Cell Published 14 February 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyProteomicsMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Share the page Share on 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The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes Authors (11)Anastasiya KazachenkaJane LoongJan AttigGeorge YoungPiyali Ganguli Ginny Devonshire Nicola Grehan The OCCAMS ConsortiumFrancesca Ciccarelli Rebecca C FitzgeraldGeorge Kassiotis NAR Cancer Published 1 September 2023 Crick labs/ facilitiesGeorge KassiotisFrancesca CiccarelliBioinformatics and BiostatisticsScientific computingCell ServicesAdvanced SequencingFull details
Innate virus-sensing pathways in B cell systemic autoimmunity Authors (3)Carola Vinuesa Amalie GrenovGeorge Kassiotis Science Published 5 May 2023 Crick labsCarola VinuesaGeorge KassiotisFull details
Antibodies against endogenous retroviruses promote lung cancer immunotherapy Authors (51)Kevin NgJesse BoumelhaKatey EnfieldJorge Almagro Hongui Cha Oriol Pich[...] Se-Hoon LeeSamra TurajlicCharles SwantonJulian DownwardGeorge Kassiotis Nature Published 20 April 2023 Crick labs/ facilitiesRobert J WilkinsonPeter Van LooSamra TurajlicCharles SwantonGeorge KassiotisJulian DownwardAxel BehrensFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingProteomicsLight MicroscopyCell ServicesBiological Research FacilityFull details
Genomic-transcriptomic evolution in lung cancer and metastasis Authors (47) Carlos Martínez-Ruiz James RM Black Clare Puttick Mark S HillJonas DemeulemeesterElizabeth Larose Cadieux[...] Peter Van Loo Mariam Jamal-Hanjani TRACERx Consortium Charles Swanton Nicholas McGranahan Nature Published 20 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisJulian DownwardFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Lung adenocarcinoma promotion by air pollutants Authors (72)William HillEmilia LimClare Weeden Claudia Lee Marcellus Augustine Kezhong Chen[...] Kevin Litchfield TRACERx Consortium James DeGregori Mariam Jamal-HanjaniCharles Swanton Nature Published 6 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonIlaria MalanchiGeorge KassiotisJulian DownwardFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingLight MicroscopyBiological Research FacilityFull details
An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations Authors (26)Jesse BoumelhaSophie de Carne Emily K Law Pablo Romero-Clavijo Matthew A CoelhoKevin Ng[...]George KassiotisMiriam Molina ArcasCharles Swanton Reuben HarrisJulian Downward Cancer Research Published 1 October 2022 Crick labs/ facilitiesCharles SwantonGeorge KassiotisJulian DownwardExperimental HistopathologyBioinformatics and BiostatisticsScientific computingFlow CytometryCell ServicesBiological Research FacilityFull details
GREM1 is required to maintain cellular heterogeneity in pancreatic cancer Authors (21) Linxiang Lan Theodore Evan Huafu Li Aasia Hussain E Josue Ruiz May Zaw Thin[...]Emma Nye Yulong He Changhua Zhang Anguraj SadanandamAxel Behrens Nature Published 7 July 2022 Crick labs/ facilitiesIlaria MalanchiGeorge KassiotisAxel BehrensExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer Authors (65)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary Wu Andreas M Schmitt[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE consortium Cancer Cell Published 14 February 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyProteomicsMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details