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Breadcrumb Gitta Stockinger Stockinger lab AhRimmunity Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Members Publications Fluorescent microscope image of a mouse ileum, part of the small intestine, showing expression of AhR in green. 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updated : 06 December 2023 02:14 Dysregulation of the environmental sensor Aryl hydrocarbon receptor affects differentiation of human colon organoids Authors (7)Anke LiebertMichael ShapiroMuralidhara MaradanaYing Li Nicholas Powell Matthias ZilbauerBrigitta Stockinger Cellular and Molecular Gastroenterology and Hepatology Published 7 November 2023 Crick labs/ facilitiesGitta StockingerLight MicroscopyFlow CytometryExperimental HistopathologyFull details Endothelial AHR activity prevents lung barrier disruption in viral infection Authors (13)Jack MajorStefania CrottaKatja Finsterbusch Probir ChakravartyKathleen ShahBruno Goncalves Frederico[...] Lucy Meader Alejandro Suarez-BonnetSimon PriestnallBrigitta StockingerAndreas Wack Nature Published 28 September 2023 Crick labs/ facilitiesAndreas WackGitta StockingerCaetano Reis e SousaLight MicroscopyExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details Manuka honey activates the aryl hydrocarbon receptor: implications for skin inflammation Authors (8) Abdullah A Alangari Matin D Ashoori Wisam Alwan Hannah R DaweBrigitta Stockinger Jonathan N Barker Emma Wincent Paola Di Meglio Pharmacological Research Published 1 August 2023 Crick labs/ facilitiesGitta StockingerBiological Research FacilityFull details Cell-intrinsic aryl hydrocarbon receptor signalling is required for the resolution of injury-induced colonic stem cells Authors (15)Kathleen ShahMuralidhara Maradana M Joaquina Delàs Amina Metidji Frederike Graelmann Miriam Llorian[...]Gavin KellyChris Cheshire Deendyal Bhurta Sandip B BharateBrigitta Stockinger Nature Communications Published 5 April 2022 Crick labs/ facilitiesGitta StockingerNicholas LuscombeJames BriscoeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in mice Authors (6)Nicola Diny Barbora SchonfeldovaMichael Shapiro Matthew L WinderSunita Varsani-BrownBrigitta Stockinger Journal of Experimental Medicine Published 4 April 2022 Crick labs/ facilitiesGitta StockingerGenetic Modification ServiceBiological Research FacilityFlow CytometryExperimental HistopathologyElectron MicroscopyAdvanced SequencingFull details PairGP: Gaussian process modeling of longitudinal data from paired multi-condition studies Authors (6) Michele Vantini Henrik Mannerström Sini Rautio Helena AhlforsBrigitta Stockinger Harri Lähdesmäki Computers in Biology and Medicine Published 1 April 2022 Crick labs/ facilitiesGitta StockingerBiological Research FacilityFull details Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients Authors (19) Edward J CarrMary Wu Ruth Harvey Roseanne E Billany Emma C WallGavin Kelly[...] Rachel B Jones Rona M Smith Stephen McAdoo Michelle WillicombeRupert Beale The Lancet Published 26 February 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningBioinformatics and BiostatisticsFull details Three-dose vaccination elicits neutralising antibodies against omicron Authors (26)Mary Wu Emma C Wall Edward J Carr Ruth Harvey Hermaleigh TownsleyHarriet Mears[...] Vincenzo Libri Bryan WilliamsSonia GandhiCharles SwantonDavid LV Bauer The Lancet Published 19 February 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details Regulation of intestinal immunity and tissue repair by enteric glia Authors (18)Franze ProgatzkyMichael ShapiroSong Hui Chng Bethania Garcia-CassaniCajsa Classon Selin Sevgi[...] Lewis J Entwistle Alejandro Suárez-Bonnet Mark WilsonBrigitta StockingerVassilis Pachnis Nature Published 20 October 2021 Crick labs/ facilitiesGitta StockingerVassilis PachnisExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients Authors (86) Edward J Carr Mary Wu Ruth Harvey Emma C WallGavin KellySaira Hussain[...]Emma RussellAndy RiddellSvend KjaerAnnabel BorgChloe Roustan The Lancet Published 18 September 2021 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details T cell subsets and environmental factors in Citrobacter rodentium infection Authors (1)Brigitta Stockinger Current Opinion in Microbiology Published 1 October 2021 Crick labsGitta StockingerFull details Effects of low-dose gestational TCDD exposure on behavior and on hippocampal neuron morphology and gene expression in mice Authors (14) Talia E Gileadi Abhyuday K Swamy Zoe Hore Stuart Horswell Jacob Ellegood Conor Mohan[...]Brigitta Stockinger Christer Hogstrand Jason P Lerch Cathy Fernandes M Albert Basson Environmental Health Perspectives Published 1 May 2021 Crick labs/ facilitiesGitta StockingerBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details Lumpers and splitters: Birth of Th17 cells Authors (1)Brigitta Stockinger Journal of Experimental Medicine Published 3 May 2021 Crick labsGitta StockingerFull details AHR in the intestinal microenvironment: safeguarding barrier function Authors (3)Brigitta StockingerKathleen Shah Emma Wincent Nature Reviews Gastroenterology and Hepatology Published 1 August 2021 Crick labsGitta StockingerFull details CYP1A1 enzymatic activity influences skin inflammation via regulation of the AHR pathway Authors (14) Mariela KyorevaYing Li Mariyah Hoosenally Jonathan Hardman-Smart Kirsten Morrison Isabella Tosi[...] Ulrich Mrowietz Frank O Nestle Catherine Smith Jonathan N Barker Paola Di Meglio Journal of Investigative Dermatology Published 1 June 2021 Crick labs/ facilitiesGitta StockingerFlow CytometryExperimental HistopathologyBiological Research FacilityFull details Preexisting and de novo humoral immunity to SARS-CoV-2 in humans Authors (47)Kevin NgNikhil Faulkner Georgina H CornishAnnachiara Rosa Ruth HarveySaira Hussain[...]Steve Gamblin Laura E MccoyPeter Cherepanov Eleni NastouliGeorge Kassiotis Science Published 11 December 2020 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeWorldwide Influenza CentreStructural BiologyFlow CytometryHigh Throughput ScreeningCell ServicesFull details Characterising the original anti-C5 function-blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5 Authors (5) Wioleta M Zelek Georgina E Menzies Andrea BrancaleBrigitta Stockinger Bryan Paul Morgan Immunology Published 1 October 2020 Crick labsGitta StockingerFull details Neuronal programming by microbiota regulates intestinal physiology Authors (18)Yuuki ObataAlvaro Castano Medina Stefan BoeingAna Bon Frauches Oliveira Candice FungTodd Fallesen[...] Pieter Vanden Berghe Andrew J MurrayBrigitta Stockinger Andrew J MacphersonVassilis Pachnis Nature Published 13 February 2020 Crick labs/ facilitiesGitta StockingerVassilis PachnisLight MicroscopyBioinformatics and BiostatisticsAdvanced SequencingFull details The AHR pathway represses TGFβ-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma Authors (11) Nemanja Sarić Matthew Selby Vijay Ramaswamy Marcel KoolBrigitta Stockinger Christer Hogstrand Daniel Williamson Silvia Marino Michael D Taylor Steven C Clifford M Albert Basson Scientific Reports Published 10 January 2020 Crick labsGitta StockingerFull details Aryl hydrocarbon receptor contributes to the transcriptional program of IL-10-producing regulatory B cells Authors (14) Christopher JM Piper Elizabeth C Rosser Kristine Oleinika Kiran Nistala Thomas Krausgruber André F Rendeiro[...] Scott Thomson Georgina Xanthou Christoph BockBrigitta Stockinger Claudia Mauri Cell Reports Published 12 November 2019 Crick labsGitta StockingerFull details Pagination Current page 1 Page 2 Page 3 Page 4 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Dysregulation of the environmental sensor Aryl hydrocarbon receptor affects differentiation of human colon organoids Authors (7)Anke LiebertMichael ShapiroMuralidhara MaradanaYing Li Nicholas Powell Matthias ZilbauerBrigitta Stockinger Cellular and Molecular Gastroenterology and Hepatology Published 7 November 2023 Crick labs/ facilitiesGitta StockingerLight MicroscopyFlow CytometryExperimental HistopathologyFull details
Endothelial AHR activity prevents lung barrier disruption in viral infection Authors (13)Jack MajorStefania CrottaKatja Finsterbusch Probir ChakravartyKathleen ShahBruno Goncalves Frederico[...] Lucy Meader Alejandro Suarez-BonnetSimon PriestnallBrigitta StockingerAndreas Wack Nature Published 28 September 2023 Crick labs/ facilitiesAndreas WackGitta StockingerCaetano Reis e SousaLight MicroscopyExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Manuka honey activates the aryl hydrocarbon receptor: implications for skin inflammation Authors (8) Abdullah A Alangari Matin D Ashoori Wisam Alwan Hannah R DaweBrigitta Stockinger Jonathan N Barker Emma Wincent Paola Di Meglio Pharmacological Research Published 1 August 2023 Crick labs/ facilitiesGitta StockingerBiological Research FacilityFull details
Cell-intrinsic aryl hydrocarbon receptor signalling is required for the resolution of injury-induced colonic stem cells Authors (15)Kathleen ShahMuralidhara Maradana M Joaquina Delàs Amina Metidji Frederike Graelmann Miriam Llorian[...]Gavin KellyChris Cheshire Deendyal Bhurta Sandip B BharateBrigitta Stockinger Nature Communications Published 5 April 2022 Crick labs/ facilitiesGitta StockingerNicholas LuscombeJames BriscoeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in mice Authors (6)Nicola Diny Barbora SchonfeldovaMichael Shapiro Matthew L WinderSunita Varsani-BrownBrigitta Stockinger Journal of Experimental Medicine Published 4 April 2022 Crick labs/ facilitiesGitta StockingerGenetic Modification ServiceBiological Research FacilityFlow CytometryExperimental HistopathologyElectron MicroscopyAdvanced SequencingFull details
PairGP: Gaussian process modeling of longitudinal data from paired multi-condition studies Authors (6) Michele Vantini Henrik Mannerström Sini Rautio Helena AhlforsBrigitta Stockinger Harri Lähdesmäki Computers in Biology and Medicine Published 1 April 2022 Crick labs/ facilitiesGitta StockingerBiological Research FacilityFull details
Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients Authors (19) Edward J CarrMary Wu Ruth Harvey Roseanne E Billany Emma C WallGavin Kelly[...] Rachel B Jones Rona M Smith Stephen McAdoo Michelle WillicombeRupert Beale The Lancet Published 26 February 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningBioinformatics and BiostatisticsFull details
Three-dose vaccination elicits neutralising antibodies against omicron Authors (26)Mary Wu Emma C Wall Edward J Carr Ruth Harvey Hermaleigh TownsleyHarriet Mears[...] Vincenzo Libri Bryan WilliamsSonia GandhiCharles SwantonDavid LV Bauer The Lancet Published 19 February 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details
Regulation of intestinal immunity and tissue repair by enteric glia Authors (18)Franze ProgatzkyMichael ShapiroSong Hui Chng Bethania Garcia-CassaniCajsa Classon Selin Sevgi[...] Lewis J Entwistle Alejandro Suárez-Bonnet Mark WilsonBrigitta StockingerVassilis Pachnis Nature Published 20 October 2021 Crick labs/ facilitiesGitta StockingerVassilis PachnisExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients Authors (86) Edward J Carr Mary Wu Ruth Harvey Emma C WallGavin KellySaira Hussain[...]Emma RussellAndy RiddellSvend KjaerAnnabel BorgChloe Roustan The Lancet Published 18 September 2021 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details
T cell subsets and environmental factors in Citrobacter rodentium infection Authors (1)Brigitta Stockinger Current Opinion in Microbiology Published 1 October 2021 Crick labsGitta StockingerFull details
Effects of low-dose gestational TCDD exposure on behavior and on hippocampal neuron morphology and gene expression in mice Authors (14) Talia E Gileadi Abhyuday K Swamy Zoe Hore Stuart Horswell Jacob Ellegood Conor Mohan[...]Brigitta Stockinger Christer Hogstrand Jason P Lerch Cathy Fernandes M Albert Basson Environmental Health Perspectives Published 1 May 2021 Crick labs/ facilitiesGitta StockingerBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details
Lumpers and splitters: Birth of Th17 cells Authors (1)Brigitta Stockinger Journal of Experimental Medicine Published 3 May 2021 Crick labsGitta StockingerFull details
AHR in the intestinal microenvironment: safeguarding barrier function Authors (3)Brigitta StockingerKathleen Shah Emma Wincent Nature Reviews Gastroenterology and Hepatology Published 1 August 2021 Crick labsGitta StockingerFull details
CYP1A1 enzymatic activity influences skin inflammation via regulation of the AHR pathway Authors (14) Mariela KyorevaYing Li Mariyah Hoosenally Jonathan Hardman-Smart Kirsten Morrison Isabella Tosi[...] Ulrich Mrowietz Frank O Nestle Catherine Smith Jonathan N Barker Paola Di Meglio Journal of Investigative Dermatology Published 1 June 2021 Crick labs/ facilitiesGitta StockingerFlow CytometryExperimental HistopathologyBiological Research FacilityFull details
Preexisting and de novo humoral immunity to SARS-CoV-2 in humans Authors (47)Kevin NgNikhil Faulkner Georgina H CornishAnnachiara Rosa Ruth HarveySaira Hussain[...]Steve Gamblin Laura E MccoyPeter Cherepanov Eleni NastouliGeorge Kassiotis Science Published 11 December 2020 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeWorldwide Influenza CentreStructural BiologyFlow CytometryHigh Throughput ScreeningCell ServicesFull details
Characterising the original anti-C5 function-blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5 Authors (5) Wioleta M Zelek Georgina E Menzies Andrea BrancaleBrigitta Stockinger Bryan Paul Morgan Immunology Published 1 October 2020 Crick labsGitta StockingerFull details
Neuronal programming by microbiota regulates intestinal physiology Authors (18)Yuuki ObataAlvaro Castano Medina Stefan BoeingAna Bon Frauches Oliveira Candice FungTodd Fallesen[...] Pieter Vanden Berghe Andrew J MurrayBrigitta Stockinger Andrew J MacphersonVassilis Pachnis Nature Published 13 February 2020 Crick labs/ facilitiesGitta StockingerVassilis PachnisLight MicroscopyBioinformatics and BiostatisticsAdvanced SequencingFull details
The AHR pathway represses TGFβ-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma Authors (11) Nemanja Sarić Matthew Selby Vijay Ramaswamy Marcel KoolBrigitta Stockinger Christer Hogstrand Daniel Williamson Silvia Marino Michael D Taylor Steven C Clifford M Albert Basson Scientific Reports Published 10 January 2020 Crick labsGitta StockingerFull details
Aryl hydrocarbon receptor contributes to the transcriptional program of IL-10-producing regulatory B cells Authors (14) Christopher JM Piper Elizabeth C Rosser Kristine Oleinika Kiran Nistala Thomas Krausgruber André F Rendeiro[...] Scott Thomson Georgina Xanthou Christoph BockBrigitta Stockinger Claudia Mauri Cell Reports Published 12 November 2019 Crick labsGitta StockingerFull details