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Breadcrumb Hasan Yardimci Yardimci lab Single Molecule Imaging of Genome Duplication and Maintenance Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Multiple laser lines that are used for single-molecule TIRF (total-internal fluorescence) imaging. Toggle to view hero caption PublicationsYear published2024 (1)2023 (2)2022 (1)2021 (1)2020 (3)2019 (3)2014 (2)2012 (2)2011 (1)2010 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (10)Cell Cycle & Chromosomes (10)Genome Integrity & Repair (10)Imaging (10)Structural Biology & Biophysics (10)Chemical Biology & High Throughput (2)Model Organisms (2)Cell Biology (1)Genetics & Genomics (1)Infectious Disease (1) Facet Research topicsCrick/Pre-CrickCrick publications (12)Pre-Crick publications (5) Facet Crick/Pre-CrickPublication typeJournal article (17)Primary research (15)Review (2) Facet Publication typeJournalNature Communications (4)Cell (2)Cell Reports (2)Molecular Cell (2)Essays in Biochemistry (1)Methods (1)Nature (1)Nature Structural & Molecular Biology (1)Science (1)Science advances (1)Scientific Reports (1) Facet Journal Publications Displaying 1 - 17 of 17Last updated : 29 March 2024 03:41 Sister chromatid cohesion establishment during DNA replication termination Authors (9)George CameronDominika Gruszka Rhian GruarSherry XieCagla Kaya Kim A Nasmyth Jonathan Baxter Madhusudhan SrinivasanHasan Yardimci Science Published 14 March 2024 Crick labs/ facilitiesHasan YardimciChemical BiologyBiological Research FacilityFull details The bacterial replication origin BUS promotes nucleobase capture Authors (15) Simone Pelliciari Salomé Bodet-Lefèvre Stepan Fenyk Daniel Stevens Charles Winterhalter Frederic D Schramm[...] Yumiko Tashiro Julia HubbardHasan Yardimci Aravindan Ilangovan Heath Murray Nature Communications Published 14 December 2023 Crick labsHasan YardimciFull details Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein Authors (11)Ondrej BelanLuke Greenhough Lucas KuhlenRoopesh Anand Artur KaczmarczykDominika GruszkaHasan YardimciXiaodong Zhang David S RuedaStephen WestSimon Boulton Molecular Cell Published 17 August 2023 Crick labsHasan YardimciStephen WestSimon BoultonFull details Multivalent interactions essential for lentiviral integrase function Authors (20)Allison Ballandras-ColasVidya ChivukulaDominika Gruszka Zelin Shan Parmit K SinghVal Pye[...]Ian Taylor Dmitry LyumkisHasan Yardimci Alan N EngelmanPeter Cherepanov Nature Communications Published 3 May 2022 Crick labs/ facilitiesHasan YardimciIan TaylorPeter Cherepanov Structural BiologyFull details Studying chromosome biology with single-molecule resolution in Xenopus laevis egg extracts Authors (2)George CameronHasan Yardimci Essays in Biochemistry Published 16 April 2021 Crick labsHasan YardimciFull details Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replication Authors (4)Dominika GruszkaSherry Xie H KimuraHasan Yardimci Science advances Published 16 September 2020 Crick labsHasan YardimciFull details Three-dimensional super-resolution fluorescence imaging of DNA Authors (4)Sevim YardimciDaniel Burnham Samantha YA TerryHasan Yardimci Scientific Reports Published 27 July 2020 Crick labs/ facilitiesHasan YardimciElectron MicroscopyFull details Duplex DNA engagement and RPA oppositely regulate the DNA-unwinding rate of CMG helicase Authors (5)Hazal KoseSherry XieGeorge Cameron Melania S StrycharskaHasan Yardimci Nature Communications Published 24 July 2020 Crick labs/ facilitiesHasan YardimciCell ServicesFull details Molecular basis for ATP-hydrolysis-driven DNA translocation by the CMG helicase of the eukaryotic replisome Authors (12)Carl EickhoffHazal KoseFabrizio Martino Tatjana Petojevic Ferdos Abid AliJulia Locke[...]Andrea Nans James M Berger Michael R BotchanHasan YardimciAlessandro Costa Cell Reports Published 3 September 2019 Crick labs/ facilitiesHasan YardimciAlessandro CostaStructural BiologyElectron MicroscopyFull details The mechanism of DNA unwinding by the eukaryotic replicative helicase Authors (4)Daniel BurnhamHazal Kose Rebecca B HoyleHasan Yardimci Nature Communications Published 14 May 2019 Crick labs/ facilitiesHasan YardimciBioinformatics and BiostatisticsFull details Dynamics of the eukaryotic replicative helicase at lagging-strand protein barriers support the steric exclusion model Authors (4)Hazal Kose Nicolai B Larsen Julien P DuxinHasan Yardimci Cell Reports Published 19 February 2019 Crick labs/ facilitiesHasan YardimciStructural BiologyCell ServicesFull details Repair of a DNA-protein crosslink by replication-coupled proteolysis Authors (4) Julien P Duxin James M DewarHasan Yardimci Johannes C Walter Cell Published 9 October 2014 Crick labsHasan YardimciFull details Prereplication-complex formation: a molecular double take? Authors (2)Hasan Yardimci Johannes C Walter Nature Structural & Molecular Biology Published 1 January 2014 Crick labsHasan YardimciFull details Bypass of a protein barrier by a replicative DNA helicase Authors (8)Hasan Yardimci Xindan Wang Anna B Loveland Inger Tappin David Z Rudner Jerard Hurwitz Antoine M van Oijen Johannes C Walter Nature Published 13 December 2012 Crick labsHasan YardimciFull details Single-molecule analysis of DNA replication in Xenopus egg extracts Authors (4)Hasan Yardimci Anna B Loveland Antoine M van Oijen Johannes C Walter Methods Published 1 June 2012 Crick labsHasan YardimciFull details Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase Authors (10) Yu V FuHasan Yardimci David T Long The Vinh Ho Angelo Guainazzi Vladimir P Bermudez Jerard Hurwitz Antoine van Oijen Orlando D Schärer Johannes C Walter Cell Published 16 September 2011 Crick labsHasan YardimciFull details Uncoupling of sister replisomes during eukaryotic DNA replication Authors (5)Hasan Yardimci Anna B Loveland Satoshi Habuchi Antoine M van Oijen Johannes C Walter Molecular Cell Published 10 December 2010 Crick labsHasan YardimciFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Sister chromatid cohesion establishment during DNA replication termination Authors (9)George CameronDominika Gruszka Rhian GruarSherry XieCagla Kaya Kim A Nasmyth Jonathan Baxter Madhusudhan SrinivasanHasan Yardimci Science Published 14 March 2024 Crick labs/ facilitiesHasan YardimciChemical BiologyBiological Research FacilityFull details
The bacterial replication origin BUS promotes nucleobase capture Authors (15) Simone Pelliciari Salomé Bodet-Lefèvre Stepan Fenyk Daniel Stevens Charles Winterhalter Frederic D Schramm[...] Yumiko Tashiro Julia HubbardHasan Yardimci Aravindan Ilangovan Heath Murray Nature Communications Published 14 December 2023 Crick labsHasan YardimciFull details
Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein Authors (11)Ondrej BelanLuke Greenhough Lucas KuhlenRoopesh Anand Artur KaczmarczykDominika GruszkaHasan YardimciXiaodong Zhang David S RuedaStephen WestSimon Boulton Molecular Cell Published 17 August 2023 Crick labsHasan YardimciStephen WestSimon BoultonFull details
Multivalent interactions essential for lentiviral integrase function Authors (20)Allison Ballandras-ColasVidya ChivukulaDominika Gruszka Zelin Shan Parmit K SinghVal Pye[...]Ian Taylor Dmitry LyumkisHasan Yardimci Alan N EngelmanPeter Cherepanov Nature Communications Published 3 May 2022 Crick labs/ facilitiesHasan YardimciIan TaylorPeter Cherepanov Structural BiologyFull details
Studying chromosome biology with single-molecule resolution in Xenopus laevis egg extracts Authors (2)George CameronHasan Yardimci Essays in Biochemistry Published 16 April 2021 Crick labsHasan YardimciFull details
Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replication Authors (4)Dominika GruszkaSherry Xie H KimuraHasan Yardimci Science advances Published 16 September 2020 Crick labsHasan YardimciFull details
Three-dimensional super-resolution fluorescence imaging of DNA Authors (4)Sevim YardimciDaniel Burnham Samantha YA TerryHasan Yardimci Scientific Reports Published 27 July 2020 Crick labs/ facilitiesHasan YardimciElectron MicroscopyFull details
Duplex DNA engagement and RPA oppositely regulate the DNA-unwinding rate of CMG helicase Authors (5)Hazal KoseSherry XieGeorge Cameron Melania S StrycharskaHasan Yardimci Nature Communications Published 24 July 2020 Crick labs/ facilitiesHasan YardimciCell ServicesFull details
Molecular basis for ATP-hydrolysis-driven DNA translocation by the CMG helicase of the eukaryotic replisome Authors (12)Carl EickhoffHazal KoseFabrizio Martino Tatjana Petojevic Ferdos Abid AliJulia Locke[...]Andrea Nans James M Berger Michael R BotchanHasan YardimciAlessandro Costa Cell Reports Published 3 September 2019 Crick labs/ facilitiesHasan YardimciAlessandro CostaStructural BiologyElectron MicroscopyFull details
The mechanism of DNA unwinding by the eukaryotic replicative helicase Authors (4)Daniel BurnhamHazal Kose Rebecca B HoyleHasan Yardimci Nature Communications Published 14 May 2019 Crick labs/ facilitiesHasan YardimciBioinformatics and BiostatisticsFull details
Dynamics of the eukaryotic replicative helicase at lagging-strand protein barriers support the steric exclusion model Authors (4)Hazal Kose Nicolai B Larsen Julien P DuxinHasan Yardimci Cell Reports Published 19 February 2019 Crick labs/ facilitiesHasan YardimciStructural BiologyCell ServicesFull details
Repair of a DNA-protein crosslink by replication-coupled proteolysis Authors (4) Julien P Duxin James M DewarHasan Yardimci Johannes C Walter Cell Published 9 October 2014 Crick labsHasan YardimciFull details
Prereplication-complex formation: a molecular double take? Authors (2)Hasan Yardimci Johannes C Walter Nature Structural & Molecular Biology Published 1 January 2014 Crick labsHasan YardimciFull details
Bypass of a protein barrier by a replicative DNA helicase Authors (8)Hasan Yardimci Xindan Wang Anna B Loveland Inger Tappin David Z Rudner Jerard Hurwitz Antoine M van Oijen Johannes C Walter Nature Published 13 December 2012 Crick labsHasan YardimciFull details
Single-molecule analysis of DNA replication in Xenopus egg extracts Authors (4)Hasan Yardimci Anna B Loveland Antoine M van Oijen Johannes C Walter Methods Published 1 June 2012 Crick labsHasan YardimciFull details
Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase Authors (10) Yu V FuHasan Yardimci David T Long The Vinh Ho Angelo Guainazzi Vladimir P Bermudez Jerard Hurwitz Antoine van Oijen Orlando D Schärer Johannes C Walter Cell Published 16 September 2011 Crick labsHasan YardimciFull details
Uncoupling of sister replisomes during eukaryotic DNA replication Authors (5)Hasan Yardimci Anna B Loveland Satoshi Habuchi Antoine M van Oijen Johannes C Walter Molecular Cell Published 10 December 2010 Crick labsHasan YardimciFull details