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Breadcrumb James Briscoe Briscoe lab Developmental Dynamics Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Collage of data and images examining the genes and mechanisms involved in spinal cord cell development. 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updated : 25 March 2023 03:13 Optogenetic closed-loop feedback control of the unfolded protein response optimizes protein production Authors (5) Moritz BenischDirk Benzinger Sant Kumar Hanrong Hu Mustafa Khammash Metabolic Engineering Published 1 May 2023 Crick labsJames BriscoeFull details New year, new developments: a look back and a look ahead Authors (2)James Briscoe Katherine Brown Development Published 1 January 2023 Crick labsJames BriscoeFull details Developmental cell fate choice in neural tube progenitors employs two distinct cis-regulatory strategies Authors (10)Joaquina Delas Vives Christos M Kalaitzis Tamara FawziMaddy DemuthIsabel ZhangHannah Stuart Elena CostantiniKenzo Ivanovitch Elly M TanakaJames Briscoe Developmental Cell Published 9 January 2023 Crick labs/ facilitiesJames BriscoeStructural BiologyScientific computingLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details The Pathway to Independence programme: helping postdocs navigate the transition to independence Authors (2)James Briscoe Katherine Brown Development Published 1 December 2022 Crick labsJames BriscoeFull details 3D ECM-rich environment sustains the identity of naive human iPSCs Authors (19) Elisa Cesare Anna UrciuoloHannah Stuart Erika Torchio Alessia Gesualdo Cecilia Laterza[...] Riccardo M Betto Graziano Martello Davide Cacchiarelli Camilla Luni Nicola Elvassore Cell Stem Cell Published 1 December 2022 Crick labsJames BriscoeFull details ERK1/2 signalling dynamics promote neural differentiation by regulating chromatin accessibility and the polycomb repressive complex Authors (7) Claudia I Semprich Lindsay Davidson Adriana Amorim Torres Harshil PatelJames BriscoeVicki Metzis Kate G Storey PLOS Biology Published 1 December 2022 Crick labs/ facilitiesJames BriscoeBioinformatics and BiostatisticsFull details Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension Authors (10) Min Bao Jake Cornwall-Scoones Estefania Sanchez-Vasquez Dong-Yuan ChenJoachim De Jonghe Shahriar Shadkhoo Florian Hollfelder Matt Thomson David M Glover Magdalena Zernicka-Goetz Nature Cell Biology Published 1 September 2022 Crick labsJames BriscoeFull details DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential Authors (17)Bruno Goncalves Frederico Isaura Martins Diana ChapelaFrancesca Gasparrini Probir ChakravartyTobias Ackels[...]James BriscoeFrancois GuillemotAndreas Schaefer Leonor SaúdeCaetano Reis e Sousa Developmental Cell Published 22 August 2022 Crick labs/ facilitiesAndreas SchaeferCaetano Reis e SousaFrancois GuillemotJames BriscoeLight MicroscopyExperimental HistopathologyElectron MicroscopyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details In preprints: morphogens in motion Authors (2) Kristina S StapornwongkulJames Briscoe Development Published 15 July 2022 Crick labsJames BriscoeFull details Sox8 remodels the cranial ectoderm to generate the ear Authors (5) Ailin Leticia Buzzi Jingchen Chen Alexandre ThieryJulien Delile Andrea Streit Proceedings of the National Academy of Sciences of USA Published 12 July 2022 Crick labsJames BriscoeFull details Dynamical landscapes of cell fate decisions Authors (3)Meritxell Saez CornellanaJames Briscoe DA Rand Interface focus Published 6 August 2022 Crick labsJames BriscoeFull details Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation Authors (7)Robert Blassberg Harshil Patel Thomas Watson Mina GoutiVicki MetzisJoaquina Delas VivesJames Briscoe Nature Cell Biology Published 1 May 2022 Crick labs/ facilitiesJames BriscoeBioinformatics and BiostatisticsFlow CytometryAdvanced SequencingFull details Cell-intrinsic aryl hydrocarbon receptor signalling is required for the resolution of injury-induced colonic stem cells Authors (15)Kathleen ShahMurali Maradana M Joaquina Delàs Amina Metidji Frederike Graelmann Miriam Llorian[...]Gavin KellyChris Cheshire Deendyal Bhurta Sandip B BharateBrigitta Stockinger Nature Communications Published 5 April 2022 Crick labs/ facilitiesGitta StockingerNicholas LuscombeJames BriscoeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details Preprints in Development Authors (2)James Briscoe Seema Grewal Development Published 1 April 2022 Crick labsJames BriscoeFull details Another year of Developments Authors (2)James Briscoe Seema Grewal Development Published 1 January 2022 Crick labsJames BriscoeFull details Free recall scaling laws and short-term memory effects in a latching attractor network Authors (3) Vezha Boboeva Alberto Pezzotta Claudia Clopath Proceedings of the National Academy of Sciences of USA Published 7 December 2021 Crick labsJames BriscoeFull details A shared transcriptional code orchestrates temporal patterning of the central nervous system Authors (6)Andreas SagnerIsabel Zhang Thomas Watson Jorge LazaroManuela MelchiondaJames Briscoe PLOS Biology Published 12 November 2021 Crick labs/ facilitiesJames BriscoeLight MicroscopyGenomics/Equipment ParkFlow CytometryBiological Research FacilityFull details Imaging development, stem cells and regeneration Authors (5) Swathi ArurJames Briscoe Yka Helariutta Thomas Lecuit Liz Robertson Development Published 15 September 2021 Crick labsJames BriscoeFull details How development supports early career researchers Authors (2)James Briscoe Seema Grewal Development Published 1 October 2021 Crick labsJames BriscoeFull details Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions Authors (6)Meritxell Saez CornellanaRobert Blassberg Elena Camacho-Aguilar Eric D Siggia David A RandJames Briscoe Cell systems Published 19 January 2022 Crick labs/ facilitiesJames BriscoeScientific computingFlow CytometryFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Optogenetic closed-loop feedback control of the unfolded protein response optimizes protein production Authors (5) Moritz BenischDirk Benzinger Sant Kumar Hanrong Hu Mustafa Khammash Metabolic Engineering Published 1 May 2023 Crick labsJames BriscoeFull details
New year, new developments: a look back and a look ahead Authors (2)James Briscoe Katherine Brown Development Published 1 January 2023 Crick labsJames BriscoeFull details
Developmental cell fate choice in neural tube progenitors employs two distinct cis-regulatory strategies Authors (10)Joaquina Delas Vives Christos M Kalaitzis Tamara FawziMaddy DemuthIsabel ZhangHannah Stuart Elena CostantiniKenzo Ivanovitch Elly M TanakaJames Briscoe Developmental Cell Published 9 January 2023 Crick labs/ facilitiesJames BriscoeStructural BiologyScientific computingLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
The Pathway to Independence programme: helping postdocs navigate the transition to independence Authors (2)James Briscoe Katherine Brown Development Published 1 December 2022 Crick labsJames BriscoeFull details
3D ECM-rich environment sustains the identity of naive human iPSCs Authors (19) Elisa Cesare Anna UrciuoloHannah Stuart Erika Torchio Alessia Gesualdo Cecilia Laterza[...] Riccardo M Betto Graziano Martello Davide Cacchiarelli Camilla Luni Nicola Elvassore Cell Stem Cell Published 1 December 2022 Crick labsJames BriscoeFull details
ERK1/2 signalling dynamics promote neural differentiation by regulating chromatin accessibility and the polycomb repressive complex Authors (7) Claudia I Semprich Lindsay Davidson Adriana Amorim Torres Harshil PatelJames BriscoeVicki Metzis Kate G Storey PLOS Biology Published 1 December 2022 Crick labs/ facilitiesJames BriscoeBioinformatics and BiostatisticsFull details
Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension Authors (10) Min Bao Jake Cornwall-Scoones Estefania Sanchez-Vasquez Dong-Yuan ChenJoachim De Jonghe Shahriar Shadkhoo Florian Hollfelder Matt Thomson David M Glover Magdalena Zernicka-Goetz Nature Cell Biology Published 1 September 2022 Crick labsJames BriscoeFull details
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential Authors (17)Bruno Goncalves Frederico Isaura Martins Diana ChapelaFrancesca Gasparrini Probir ChakravartyTobias Ackels[...]James BriscoeFrancois GuillemotAndreas Schaefer Leonor SaúdeCaetano Reis e Sousa Developmental Cell Published 22 August 2022 Crick labs/ facilitiesAndreas SchaeferCaetano Reis e SousaFrancois GuillemotJames BriscoeLight MicroscopyExperimental HistopathologyElectron MicroscopyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details
In preprints: morphogens in motion Authors (2) Kristina S StapornwongkulJames Briscoe Development Published 15 July 2022 Crick labsJames BriscoeFull details
Sox8 remodels the cranial ectoderm to generate the ear Authors (5) Ailin Leticia Buzzi Jingchen Chen Alexandre ThieryJulien Delile Andrea Streit Proceedings of the National Academy of Sciences of USA Published 12 July 2022 Crick labsJames BriscoeFull details
Dynamical landscapes of cell fate decisions Authors (3)Meritxell Saez CornellanaJames Briscoe DA Rand Interface focus Published 6 August 2022 Crick labsJames BriscoeFull details
Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation Authors (7)Robert Blassberg Harshil Patel Thomas Watson Mina GoutiVicki MetzisJoaquina Delas VivesJames Briscoe Nature Cell Biology Published 1 May 2022 Crick labs/ facilitiesJames BriscoeBioinformatics and BiostatisticsFlow CytometryAdvanced SequencingFull details
Cell-intrinsic aryl hydrocarbon receptor signalling is required for the resolution of injury-induced colonic stem cells Authors (15)Kathleen ShahMurali Maradana M Joaquina Delàs Amina Metidji Frederike Graelmann Miriam Llorian[...]Gavin KellyChris Cheshire Deendyal Bhurta Sandip B BharateBrigitta Stockinger Nature Communications Published 5 April 2022 Crick labs/ facilitiesGitta StockingerNicholas LuscombeJames BriscoeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
Preprints in Development Authors (2)James Briscoe Seema Grewal Development Published 1 April 2022 Crick labsJames BriscoeFull details
Another year of Developments Authors (2)James Briscoe Seema Grewal Development Published 1 January 2022 Crick labsJames BriscoeFull details
Free recall scaling laws and short-term memory effects in a latching attractor network Authors (3) Vezha Boboeva Alberto Pezzotta Claudia Clopath Proceedings of the National Academy of Sciences of USA Published 7 December 2021 Crick labsJames BriscoeFull details
A shared transcriptional code orchestrates temporal patterning of the central nervous system Authors (6)Andreas SagnerIsabel Zhang Thomas Watson Jorge LazaroManuela MelchiondaJames Briscoe PLOS Biology Published 12 November 2021 Crick labs/ facilitiesJames BriscoeLight MicroscopyGenomics/Equipment ParkFlow CytometryBiological Research FacilityFull details
Imaging development, stem cells and regeneration Authors (5) Swathi ArurJames Briscoe Yka Helariutta Thomas Lecuit Liz Robertson Development Published 15 September 2021 Crick labsJames BriscoeFull details
How development supports early career researchers Authors (2)James Briscoe Seema Grewal Development Published 1 October 2021 Crick labsJames BriscoeFull details
Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions Authors (6)Meritxell Saez CornellanaRobert Blassberg Elena Camacho-Aguilar Eric D Siggia David A RandJames Briscoe Cell systems Published 19 January 2022 Crick labs/ facilitiesJames BriscoeScientific computingFlow CytometryFull details