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False-colored nuclei of the embryonic epidermis of Drosophila (credit: Sam Crossman) Toggle to view hero caption Jean-Paul Vincent : Publications Lab MenuLab Menu Overview Areas of interest View more Back Modulation Cell elimination Publications Members Vacancies Breadcrumb Research A Z of research labs Jean Paul Vincent PublicationsYear published2021 (4)2020 (4)2019 (1)2018 (5)2017 (3)2016 (7)2015 (1)2014 (6)2013 (4)2012 (2)2011 (4)2010 (3) Facet Year publishedResearch topicsCell Biology (24)Developmental Biology (24)Genetics & Genomics (24)Imaging (24)Model Organisms (24)Neurosciences (24)Signalling & Oncogenes (24)Synthetic Biology (24)Structural Biology & Biophysics (5)Chemical Biology & High Throughput (4)Computational & Systems Biology (4)Biochemistry & Proteomics (2) Facet Research topicsPublication typeJournal article (44)Primary research (29)Review (13)Commentary (2) Facet Publication typeJournalDevelopment (6)Developmental Cell (4)Nature (3)Nature Cell Biology (3)Current Biology (2)eLife (2)EMBO Journal (2)Journal of Medicinal Chemistry (2)Cell (1)Communications in Mathematical Sciences (1)Current Opinion in Cell Biology (1)EMBO Reports (1)Genetics (1)Journal of Cell Science (1)Mathematical Biosciences and Engineering (1)Methods (1)Molecular Metabolism (1)Nature Communications (1)Nature Reviews Genetics (1)Nature Reviews Molecular Cell Biology (1)Nature Structural & Molecular Biology (1)Open Biology (1)PLOS Biology (1)PLOS Genetics (1)Science (1)Science Signaling (1)Traffic (1)Trends in Cell Biology (1) Facet Journal Publications Displaying 1 - 20 of 44Last updated : 07 May 2021 02:27 Carboxylesterase Notum is a druggable target to modulate Wnt signaling Authors (9) Elliott D Bayle Fredrik Svensson Benjamin N Atkinson David Steadman Nicky J Willis Hannah L Woodward Paul WhitingJean-Paul Vincent Paul V Fish Journal of Medicinal Chemistry Published 22 April 2021 Crick labsJean-Paul VincentFull details Generation of extracellular morphogen gradients: the case for diffusion Authors (2)Kristina StapornwongkulJean-Paul Vincent Nature Reviews Genetics Published 25 March 2021 Crick labsJean-Paul VincentFull details Notum deacylates octanoylated ghrelin Authors (11) Yuguang ZhaoLaura Nadine SchuhmacherMorgan Roberts Satoshi KakugawaGanka Bineva-Todd Steve HowellNicola O'Reilly Christine PerretBram SnijdersJean-Paul Vincent E Yvonne Jones Molecular Metabolism Published 1 July 2021 Crick labs/ facilitiesJean-Paul VincentProteomicsPeptide ChemistryFull details Ribosomopathy-associated mutations cause proteotoxic stress that is alleviated by TOR inhibition Authors (7)Carles Recasens AlvarezCyrille AlexandreJoanna Kirkpatrick Hisashi Nojima David J HuelsBram SnijdersJean-Paul Vincent Nature Cell Biology Published 1 February 2021 Crick labs/ facilitiesJean-Paul VincentProteomicsFull details 5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit Authors (18) William Mahy Nicky J Willis Yuguang Zhao Hannah L Woodward Fredrik Svensson James Sipthorp[...] Patricia C Salinas Paul WhitingJean-Paul Vincent E Yvonne Jones Paul V Fish Journal of Medicinal Chemistry Published 12 November 2020 Crick labs/ facilitiesJean-Paul VincentStructural BiologyFull details Patterning and growth control in vivo by an engineered GFP gradient Authors (5)Kristina StapornwongkulMarc De Gennes Luca CocconiGuillaume SalbreuxJean-Paul Vincent Science Published 16 October 2020 Crick labsJean-Paul VincentGuillaume SalbreuxFull details Frizzled-dependent planar cell polarity without secreted Wnt ligands Authors (7)Joyce Yu Aude Maugarny-Calès Stéphane PelletierCyrille Alexandre Yohanns BellaicheJean-Paul VincentIan Mcgough Developmental Cell Published 14 September 2020 Crick labsJean-Paul VincentFull details Glypicans shield the Wnt lipid moiety to enable signalling at a distance Authors (10)Ian Mcgough Luca Vecchia Benjamin Bishop Tomas Malinauskas Karen BeckettDhira JoshiNicola O'Reilly Christian Siebold E Yvonne JonesJean-Paul Vincent Nature Published 3 September 2020 Crick labs/ facilitiesJean-Paul VincentPeptide ChemistryFull details Incompressible limit of a continuum model of tissue growth with segregation for two cell populations Authors (4) A Chertock P Degond S HechtJean-Paul Vincent Mathematical Biosciences and Engineering Published 22 June 2019 Crick labsJean-Paul VincentFull details Novel initiator caspase reporters uncover previously unknown features of caspase-activating cells Authors (6) Luis Alberto Baena-Lopez Lewis Arthurton Marcus BischoffJean-Paul VincentCyrille Alexandre Reuben McGregor Development Published 4 December 2018 Crick labsJean-Paul VincentFull details Epithelial cells release adenosine to promote local TNF production in response to polarity disruption Authors (2)Ingrid PoernbacherJean-Paul Vincent Nature Communications Published 7 November 2018 Crick labsJean-Paul VincentFull details EGFR signaling coordinates patterning with cell survival during Drosophila epidermal development Authors (3)Samuel Crossman Sebastian J StreichanJean-Paul Vincent PLOS Biology Published 31 October 2018 Crick labs/ facilitiesJean-Paul VincentLight MicroscopyFull details Developmental biology: Morphogen in a dish Authors (3) Kristina S StapornwongkulGuillaume SalbreuxJean-Paul Vincent Current Biology Published 9 July 2018 Crick labsJean-Paul VincentGuillaume SalbreuxFull details APC moonlights to prevent wnt signalosome assembly Authors (2)Ian McgoughJean-Paul Vincent Developmental Cell Published 12 March 2018 Crick labsJean-Paul VincentFull details Incompressible limit of a mechanical model for tissue growth with non-overlapping constraint Authors (2) S Hecht N Vauchelet Communications in Mathematical Sciences Published 16 October 2017 Crick labsJean-Paul VincentFull details Notum coordinates synapse development via extracellular regulation of Wingless trans-synaptic signaling Authors (4) Danielle L Kopke Sofia C LimaCyrille Alexandre Kendal Broadie Development Published 3 October 2017 Crick labsJean-Paul VincentFull details Dpp controls growth and patterning in Drosophila wing precursors through distinct modes of action Authors (5) Pablo Sanchez BoschRuta ZiukaiteCyrille Alexandre Konrad BaslerJean-Paul Vincent eLife Published 4 July 2017 Crick labsJean-Paul VincentFull details Exosomes in developmental signalling Authors (2)Ian McgoughJean-Paul Vincent Development Published 15 July 2016 Crick labsJean-Paul VincentFull details Making, exporting, and modulating Wnts Authors (3) Paul F Langton Satoshi KakugawaJean-Paul Vincent Trends in Cell Biology Published 17 June 2016 Crick labsJean-Paul VincentFull details The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in Drosophila Authors (7) Zhenghan Wang Ai Tian Hassina Benchabane Ofelia Tacchelly-Benites Eungi Yang Hisashi Nojima Yashi Ahmed Development Published 15 May 2016 Crick labsJean-Paul VincentFull details Pagination Current page 1 Page 2 Page 3 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Carboxylesterase Notum is a druggable target to modulate Wnt signaling Authors (9) Elliott D Bayle Fredrik Svensson Benjamin N Atkinson David Steadman Nicky J Willis Hannah L Woodward Paul WhitingJean-Paul Vincent Paul V Fish Journal of Medicinal Chemistry Published 22 April 2021 Crick labsJean-Paul VincentFull details
Generation of extracellular morphogen gradients: the case for diffusion Authors (2)Kristina StapornwongkulJean-Paul Vincent Nature Reviews Genetics Published 25 March 2021 Crick labsJean-Paul VincentFull details
Notum deacylates octanoylated ghrelin Authors (11) Yuguang ZhaoLaura Nadine SchuhmacherMorgan Roberts Satoshi KakugawaGanka Bineva-Todd Steve HowellNicola O'Reilly Christine PerretBram SnijdersJean-Paul Vincent E Yvonne Jones Molecular Metabolism Published 1 July 2021 Crick labs/ facilitiesJean-Paul VincentProteomicsPeptide ChemistryFull details
Ribosomopathy-associated mutations cause proteotoxic stress that is alleviated by TOR inhibition Authors (7)Carles Recasens AlvarezCyrille AlexandreJoanna Kirkpatrick Hisashi Nojima David J HuelsBram SnijdersJean-Paul Vincent Nature Cell Biology Published 1 February 2021 Crick labs/ facilitiesJean-Paul VincentProteomicsFull details
5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit Authors (18) William Mahy Nicky J Willis Yuguang Zhao Hannah L Woodward Fredrik Svensson James Sipthorp[...] Patricia C Salinas Paul WhitingJean-Paul Vincent E Yvonne Jones Paul V Fish Journal of Medicinal Chemistry Published 12 November 2020 Crick labs/ facilitiesJean-Paul VincentStructural BiologyFull details
Patterning and growth control in vivo by an engineered GFP gradient Authors (5)Kristina StapornwongkulMarc De Gennes Luca CocconiGuillaume SalbreuxJean-Paul Vincent Science Published 16 October 2020 Crick labsJean-Paul VincentGuillaume SalbreuxFull details
Frizzled-dependent planar cell polarity without secreted Wnt ligands Authors (7)Joyce Yu Aude Maugarny-Calès Stéphane PelletierCyrille Alexandre Yohanns BellaicheJean-Paul VincentIan Mcgough Developmental Cell Published 14 September 2020 Crick labsJean-Paul VincentFull details
Glypicans shield the Wnt lipid moiety to enable signalling at a distance Authors (10)Ian Mcgough Luca Vecchia Benjamin Bishop Tomas Malinauskas Karen BeckettDhira JoshiNicola O'Reilly Christian Siebold E Yvonne JonesJean-Paul Vincent Nature Published 3 September 2020 Crick labs/ facilitiesJean-Paul VincentPeptide ChemistryFull details
Incompressible limit of a continuum model of tissue growth with segregation for two cell populations Authors (4) A Chertock P Degond S HechtJean-Paul Vincent Mathematical Biosciences and Engineering Published 22 June 2019 Crick labsJean-Paul VincentFull details
Novel initiator caspase reporters uncover previously unknown features of caspase-activating cells Authors (6) Luis Alberto Baena-Lopez Lewis Arthurton Marcus BischoffJean-Paul VincentCyrille Alexandre Reuben McGregor Development Published 4 December 2018 Crick labsJean-Paul VincentFull details
Epithelial cells release adenosine to promote local TNF production in response to polarity disruption Authors (2)Ingrid PoernbacherJean-Paul Vincent Nature Communications Published 7 November 2018 Crick labsJean-Paul VincentFull details
EGFR signaling coordinates patterning with cell survival during Drosophila epidermal development Authors (3)Samuel Crossman Sebastian J StreichanJean-Paul Vincent PLOS Biology Published 31 October 2018 Crick labs/ facilitiesJean-Paul VincentLight MicroscopyFull details
Developmental biology: Morphogen in a dish Authors (3) Kristina S StapornwongkulGuillaume SalbreuxJean-Paul Vincent Current Biology Published 9 July 2018 Crick labsJean-Paul VincentGuillaume SalbreuxFull details
APC moonlights to prevent wnt signalosome assembly Authors (2)Ian McgoughJean-Paul Vincent Developmental Cell Published 12 March 2018 Crick labsJean-Paul VincentFull details
Incompressible limit of a mechanical model for tissue growth with non-overlapping constraint Authors (2) S Hecht N Vauchelet Communications in Mathematical Sciences Published 16 October 2017 Crick labsJean-Paul VincentFull details
Notum coordinates synapse development via extracellular regulation of Wingless trans-synaptic signaling Authors (4) Danielle L Kopke Sofia C LimaCyrille Alexandre Kendal Broadie Development Published 3 October 2017 Crick labsJean-Paul VincentFull details
Dpp controls growth and patterning in Drosophila wing precursors through distinct modes of action Authors (5) Pablo Sanchez BoschRuta ZiukaiteCyrille Alexandre Konrad BaslerJean-Paul Vincent eLife Published 4 July 2017 Crick labsJean-Paul VincentFull details
Exosomes in developmental signalling Authors (2)Ian McgoughJean-Paul Vincent Development Published 15 July 2016 Crick labsJean-Paul VincentFull details
Making, exporting, and modulating Wnts Authors (3) Paul F Langton Satoshi KakugawaJean-Paul Vincent Trends in Cell Biology Published 17 June 2016 Crick labsJean-Paul VincentFull details
The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in Drosophila Authors (7) Zhenghan Wang Ai Tian Hassina Benchabane Ofelia Tacchelly-Benites Eungi Yang Hisashi Nojima Yashi Ahmed Development Published 15 May 2016 Crick labsJean-Paul VincentFull details
