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Genes in the brain are very long and can be transcribed into diverse RNAs. Toggle to view hero caption Jernej Ule : Publications Lab MenuLab Menu Overview Areas of interest View more Back RNP assembly RNP function RNP evolution RNPs in disease RNPs in Development Publications Members Vacancies Breadcrumb Home Research Labs Jernej Ule Publications PublicationsYear published2020 (4)2019 (10)2018 (13)2017 (7)2015 (3)2013 (1)Research topicsBiochemistry & Proteomics (35)Computational & Systems Biology (35)Gene Expression (35)Genetics & Genomics (35)Neurosciences (35)Stem Cells (35)Tumour Biology (11)Cell Biology (5)Cell Cycle & Chromosomes (1)Chemical Biology & High Throughput (1)Developmental Biology (1)Genome Integrity & Repair (1)Human Biology & Physiology (1)Imaging (1)Immunology (1)Infectious Disease (1)Metabolism (1)Microfabrication & Bioengineering (1)Model Organisms (1)Signalling & Oncogenes (1)Structural Biology & Biophysics (1)Synthetic Biology (1)Publication typeJournal article (38)Primary research (25)Review (8)Commentary (2)Method (2)Editorial (1)JournalMolecular Cell (5)Cell Reports (3)Nucleic Acids Research (3)Cell (2)EMBO Journal (2)EMBO Reports (2)Genome Biology (2)Nature (2)Nature Communications (2)Nature Structural and Molecular Biology (2)Annual Review of Biomedical Data Science (1)BioEssays (1)Brain (1)Cold Spring Harbor Perspectives in Biology (1)eLife (1)Frontiers in Genetics (1)Genes & Development (1)Nature Ecology & Evolution (1)Nature Protocols (1)Nature Reviews Molecular Cell Biology (1)RNA Biology (1)The Lancet (1)Wellcome Open Research (1) Publications Displaying 1 - 20 of 38Last updated : 19 September 2020 02:50 Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan Lewer Gavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesLuiz Pedro CarvalhoMike BlackmanDominique BonnetPeter Cherepanov Steve GamblinMaximiliano GutierrezGeorge KassiotisPaul NurseAnne O’GarraVenizelos PapayannopoulosLucia Prieto-GodinoPeter RatcliffeCaetano Reis e SousaErik SahaiCharles SwantonMoritz TreeckJames TurnerJernej UleKaren VousdenAndreas WackSonia GandhiRupert BealeAdam SaterialeAdvanced SequencingCell ServicesBioinformatics and BiostatisticsElectron MicroscopyExperimental HistopathologyFlow CytometryGenomics/Equipment ParkHigh Throughput ScreeningMetabolomicsPeptide ChemistryStructural BiologyFermentationWorldwide Influenza CentreHuman Embryonic Stem CellScientific computingFull details How do you identify m6 A methylation in transcriptomes at high resolution? A comparison of recent datasets Authors (4)Charlotte CapitanchikPatrick Toolan-KerrNicholas LuscombeJernej Ule Frontiers in Genetics Published 20 May 2020 Crick labsNicholas LuscombeJernej UleFull details CDK11 is required for transcription of replication-dependent histone genes Authors (6) Pavla GajduškováIgor Ruiz De Los Mozos Michal Rájecký Milan HluchýJernej Ule Dalibor Blazek Nature Structural and Molecular Biology Published 4 May 2020 Crick labsJernej UleFull details Open access, open data and peer review Authors (1)Jernej Ule Genome Biology Published 4 May 2020 Crick labsJernej UleFull details Alternative splicing regulatory networks: Functions, mechanisms, and evolution Authors (2)Jernej Ule Benjamin J Blencowe Molecular Cell Published 17 October 2019 Crick labsJernej UleFull details A systems view of spliceosomal assembly and branchpoints with iCLIP Authors (17) Michael Briese Nejc Haberman Christopher R SibleyRupert FarawayAndrea ElserAnob Chakrabarti[...] Luciano Saieva Livio Pellizzoni Christopher WJ Smith Tomaž CurkJernej Ule Nature Structural and Molecular Biology Published 30 September 2019 Crick labsNicholas LuscombeJernej UleFull details Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis Authors (12)Giulia Tyzack Raphaelle LuisierDoaa TahaJacob NeevesMiha ModicJamie Mitchell[...] Linda Greensmith Jia NewcombeJernej UleNicholas LuscombeRickie Patani Brain Published 1 September 2019 Crick labsNicholas LuscombeJernej UleRickie PataniFull details FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA Authors (7) Jean-Michel Carter Warren Emmett Igor RDL Mozos Annika Kotter Mark HelmJernej Ule Shobbir Hussain Nucleic Acids Research Published 4 November 2019 Crick labsJernej UleFull details The transcriptome-wide landscape and modalities of EJC binding in adult Drosophila Authors (5) Ales Obrdlik Gen Lin Nejc HabermanJernej Ule Anne Ephrussi Cell Reports Published 30 July 2019 Crick labsJernej UleFull details Cross-regulation between TDP-43 and paraspeckles promotes pluripotency-differentiation transition Authors (20)Miha Modic Markus Grosch Gregor Rot Silvia Schirge Tjasa Lepko Tomohiro Yamazaki[...] Alexander Meissner Heiko Lickert Tetsuro HiroseJernej Ule Micha Drukker Molecular Cell Published 6 June 2019 Crick labsJernej UleFull details P-TEFb activation by RBM7 shapes a pro-survival transcriptional response to genotoxic stress Authors (14) Andrii Bugai Alexandre JC Quaresma Caroline C Friedel Tina Lenasi Robert Düster Christopher R Sibley[...] Melanie Blasius Matthias GeyerJernej Ule Lars Dölken Matjaž Barborič Molecular Cell Published 18 April 2019 Crick labsJernej UleFull details Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock Authors (6) Violeta Castelo-Szekely Mara De Matos Marina Tusup Steve PascoloJernej Ule David Gatfield Nucleic Acids Research Published 4 June 2019 Crick labsJernej UleFull details The origin of neural microexons Authors (2) Rupert FarawayJernej Ule Nature Ecology & Evolution Published 4 March 2019 Crick labsJernej UleFull details Genomic accumulation of retrotransposons was facilitated by repressive RNA-binding proteins: A hypothesis Authors (2)Jan AttigJernej Ule BioEssays Published 1 February 2019 Crick labsJernej UleFull details The key protein of endosomal mRNP transport Rrm4 binds translational landmark sites of cargo mRNAs Authors (9) Lilli Olgeiser Carl Haag Susan BoernerJernej Ule Anke Busch Janine Koepke Julian König Michael Feldbrügge Kathi Zarnack EMBO Reports Published 14 December 2018 Crick labsJernej UleFull details Exon junction complex shapes the transcriptome by repressing recursive splicing Authors (11)Lorea Blazquez Garcia Warren EmmettRupert Faraway Jose Mario Bello Pineda Simon Bajew Andre Gohr Nejc Haberman Christopher R Sibley Robert K Bradley Manuel IrimiaJernej Ule Molecular Cell Published 1 November 2018 Crick labs/ facilitiesJernej UleCell ServicesGenomics/Equipment ParkFull details Heteromeric RNP assembly at LINEs controls lineage-specific RNA processing Authors (11)Jan Attig Federico Agostini Clare GoodingAnob Chakrabarti Aarti Singh Nejc HabermanJulian Zagalak Warren Emmett Christopher WJ SmithNicholas LuscombeJernej Ule Cell Published 2 August 2018 Crick labsNicholas LuscombeJernej UleFull details The future of cross-lnking and imunoprecipitation (CLIP) Authors (3)Jernej Ule Hun-Way Hwang Robert B Darnell Cold Spring Harbor Perspectives in Biology Published 1 August 2018 Crick labsJernej UleFull details Data science issues in studying protein–RNA interactions with CLIP technologies Authors (5) Anob M Chakrabarti Nejc Haberman Arne PraznikNicholas LuscombeJernej Ule Annual Review of Biomedical Data Science Published 1 July 2018 Crick labsNicholas LuscombeJernej UleFull details Read-through marking' reveals differential nucleotide composition of read-through and truncated cDNAs in iCLIP Authors (3) Ina Huppertz Nejc HabermanJernej Ule Wellcome Open Research Published 22 June 2018 Crick labsJernej UleFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan Lewer Gavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesLuiz Pedro CarvalhoMike BlackmanDominique BonnetPeter Cherepanov Steve GamblinMaximiliano GutierrezGeorge KassiotisPaul NurseAnne O’GarraVenizelos PapayannopoulosLucia Prieto-GodinoPeter RatcliffeCaetano Reis e SousaErik SahaiCharles SwantonMoritz TreeckJames TurnerJernej UleKaren VousdenAndreas WackSonia GandhiRupert BealeAdam SaterialeAdvanced SequencingCell ServicesBioinformatics and BiostatisticsElectron MicroscopyExperimental HistopathologyFlow CytometryGenomics/Equipment ParkHigh Throughput ScreeningMetabolomicsPeptide ChemistryStructural BiologyFermentationWorldwide Influenza CentreHuman Embryonic Stem CellScientific computingFull details
How do you identify m6 A methylation in transcriptomes at high resolution? A comparison of recent datasets Authors (4)Charlotte CapitanchikPatrick Toolan-KerrNicholas LuscombeJernej Ule Frontiers in Genetics Published 20 May 2020 Crick labsNicholas LuscombeJernej UleFull details
CDK11 is required for transcription of replication-dependent histone genes Authors (6) Pavla GajduškováIgor Ruiz De Los Mozos Michal Rájecký Milan HluchýJernej Ule Dalibor Blazek Nature Structural and Molecular Biology Published 4 May 2020 Crick labsJernej UleFull details
Open access, open data and peer review Authors (1)Jernej Ule Genome Biology Published 4 May 2020 Crick labsJernej UleFull details
Alternative splicing regulatory networks: Functions, mechanisms, and evolution Authors (2)Jernej Ule Benjamin J Blencowe Molecular Cell Published 17 October 2019 Crick labsJernej UleFull details
A systems view of spliceosomal assembly and branchpoints with iCLIP Authors (17) Michael Briese Nejc Haberman Christopher R SibleyRupert FarawayAndrea ElserAnob Chakrabarti[...] Luciano Saieva Livio Pellizzoni Christopher WJ Smith Tomaž CurkJernej Ule Nature Structural and Molecular Biology Published 30 September 2019 Crick labsNicholas LuscombeJernej UleFull details
Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis Authors (12)Giulia Tyzack Raphaelle LuisierDoaa TahaJacob NeevesMiha ModicJamie Mitchell[...] Linda Greensmith Jia NewcombeJernej UleNicholas LuscombeRickie Patani Brain Published 1 September 2019 Crick labsNicholas LuscombeJernej UleRickie PataniFull details
FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA Authors (7) Jean-Michel Carter Warren Emmett Igor RDL Mozos Annika Kotter Mark HelmJernej Ule Shobbir Hussain Nucleic Acids Research Published 4 November 2019 Crick labsJernej UleFull details
The transcriptome-wide landscape and modalities of EJC binding in adult Drosophila Authors (5) Ales Obrdlik Gen Lin Nejc HabermanJernej Ule Anne Ephrussi Cell Reports Published 30 July 2019 Crick labsJernej UleFull details
Cross-regulation between TDP-43 and paraspeckles promotes pluripotency-differentiation transition Authors (20)Miha Modic Markus Grosch Gregor Rot Silvia Schirge Tjasa Lepko Tomohiro Yamazaki[...] Alexander Meissner Heiko Lickert Tetsuro HiroseJernej Ule Micha Drukker Molecular Cell Published 6 June 2019 Crick labsJernej UleFull details
P-TEFb activation by RBM7 shapes a pro-survival transcriptional response to genotoxic stress Authors (14) Andrii Bugai Alexandre JC Quaresma Caroline C Friedel Tina Lenasi Robert Düster Christopher R Sibley[...] Melanie Blasius Matthias GeyerJernej Ule Lars Dölken Matjaž Barborič Molecular Cell Published 18 April 2019 Crick labsJernej UleFull details
Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock Authors (6) Violeta Castelo-Szekely Mara De Matos Marina Tusup Steve PascoloJernej Ule David Gatfield Nucleic Acids Research Published 4 June 2019 Crick labsJernej UleFull details
The origin of neural microexons Authors (2) Rupert FarawayJernej Ule Nature Ecology & Evolution Published 4 March 2019 Crick labsJernej UleFull details
Genomic accumulation of retrotransposons was facilitated by repressive RNA-binding proteins: A hypothesis Authors (2)Jan AttigJernej Ule BioEssays Published 1 February 2019 Crick labsJernej UleFull details
The key protein of endosomal mRNP transport Rrm4 binds translational landmark sites of cargo mRNAs Authors (9) Lilli Olgeiser Carl Haag Susan BoernerJernej Ule Anke Busch Janine Koepke Julian König Michael Feldbrügge Kathi Zarnack EMBO Reports Published 14 December 2018 Crick labsJernej UleFull details
Exon junction complex shapes the transcriptome by repressing recursive splicing Authors (11)Lorea Blazquez Garcia Warren EmmettRupert Faraway Jose Mario Bello Pineda Simon Bajew Andre Gohr Nejc Haberman Christopher R Sibley Robert K Bradley Manuel IrimiaJernej Ule Molecular Cell Published 1 November 2018 Crick labs/ facilitiesJernej UleCell ServicesGenomics/Equipment ParkFull details
Heteromeric RNP assembly at LINEs controls lineage-specific RNA processing Authors (11)Jan Attig Federico Agostini Clare GoodingAnob Chakrabarti Aarti Singh Nejc HabermanJulian Zagalak Warren Emmett Christopher WJ SmithNicholas LuscombeJernej Ule Cell Published 2 August 2018 Crick labsNicholas LuscombeJernej UleFull details
The future of cross-lnking and imunoprecipitation (CLIP) Authors (3)Jernej Ule Hun-Way Hwang Robert B Darnell Cold Spring Harbor Perspectives in Biology Published 1 August 2018 Crick labsJernej UleFull details
Data science issues in studying protein–RNA interactions with CLIP technologies Authors (5) Anob M Chakrabarti Nejc Haberman Arne PraznikNicholas LuscombeJernej Ule Annual Review of Biomedical Data Science Published 1 July 2018 Crick labsNicholas LuscombeJernej UleFull details
Read-through marking' reveals differential nucleotide composition of read-through and truncated cDNAs in iCLIP Authors (3) Ina Huppertz Nejc HabermanJernej Ule Wellcome Open Research Published 22 June 2018 Crick labsJernej UleFull details
