Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Breadcrumb Jernej Ule Ule lab RNA Networks Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Genes in the brain are very long and can be transcribed into diverse RNAs. Toggle to view hero caption PublicationsYear published2022 (2)2021 (1)2018 (1)2015 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (4)Computational & Systems Biology (4)Gene Expression (4)Genetics & Genomics (4)Neurosciences (4)Stem Cells (4)Cell Biology (1)Chemical Biology & High Throughput (1)Structural Biology & Biophysics (1) Facet Research topicsPublication typeJournal article (5)Primary research (5) Facet Publication typeJournal (-)Nature (5) Facet Journal Publications Displaying 1 - 5 of 5Last updated : 20 April 2024 03:56 CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1 Authors (15) Milan Hluchý Pavla GajduškováIgor Ruiz De Los Mozos Michal Rájecký Michael Kluge Benedict-Tilman Berger[...] Zbyněk Zdráhal Stefan Knapp Kamil Paruch Caroline C Friedel Dalibor Blazek Nature Published 22 September 2022 Crick labsJernej UleFull details TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A Authors (32) Anna-Leigh BrownOscar Wilkins Matthew J Keuss Sarah E Hill Matteo Zanovello Weaverly Colleen Lee[...]Jernej Ule Emanuele Buratti Jack Humphrey Michael E Ward Pietro Fratta Nature Published 3 March 2022 Crick labs/ facilitiesJernej UleStructural BiologyFull details MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration Authors (34) Roberto Simone Faiza Javad Warren EmmettOscar Wilkins Filipa Lourenço Almeida Natalia Barahona-Torres[...] Per Svenningsson Thomas T Warner Vincent PlagnolJernej Ule Rohan de Silva Nature Published 3 June 2021 Crick labsJernej UleRickie PataniFull details The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency Authors (18) Alessandro Bertero Stephanie Brown Pedro Madrigal Anna Osnato Daniel Ortmann Loukia Yiangou[...] Edward FarnellJernej Ule Hendrik G Stunnenberg Sasha Mendjan Ludovic Vallier Nature Published 8 March 2018 Crick labsJernej UleFull details hiCLIP reveals the in vivo atlas of mRNA secondary structures recognized by Staufen 1 Authors (8)Yoichiro Sugimoto Alessandra Vigilante Elodie Darbo Alexandra Zirra Cristina Militti Andrea D'AmbrogioNicholas LuscombeJernej Ule Nature Published 26 March 2015 Crick labsJernej UleNicholas LuscombeFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1 Authors (15) Milan Hluchý Pavla GajduškováIgor Ruiz De Los Mozos Michal Rájecký Michael Kluge Benedict-Tilman Berger[...] Zbyněk Zdráhal Stefan Knapp Kamil Paruch Caroline C Friedel Dalibor Blazek Nature Published 22 September 2022 Crick labsJernej UleFull details
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A Authors (32) Anna-Leigh BrownOscar Wilkins Matthew J Keuss Sarah E Hill Matteo Zanovello Weaverly Colleen Lee[...]Jernej Ule Emanuele Buratti Jack Humphrey Michael E Ward Pietro Fratta Nature Published 3 March 2022 Crick labs/ facilitiesJernej UleStructural BiologyFull details
MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration Authors (34) Roberto Simone Faiza Javad Warren EmmettOscar Wilkins Filipa Lourenço Almeida Natalia Barahona-Torres[...] Per Svenningsson Thomas T Warner Vincent PlagnolJernej Ule Rohan de Silva Nature Published 3 June 2021 Crick labsJernej UleRickie PataniFull details
The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency Authors (18) Alessandro Bertero Stephanie Brown Pedro Madrigal Anna Osnato Daniel Ortmann Loukia Yiangou[...] Edward FarnellJernej Ule Hendrik G Stunnenberg Sasha Mendjan Ludovic Vallier Nature Published 8 March 2018 Crick labsJernej UleFull details
hiCLIP reveals the in vivo atlas of mRNA secondary structures recognized by Staufen 1 Authors (8)Yoichiro Sugimoto Alessandra Vigilante Elodie Darbo Alexandra Zirra Cristina Militti Andrea D'AmbrogioNicholas LuscombeJernej Ule Nature Published 26 March 2015 Crick labsJernej UleNicholas LuscombeFull details
