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Diffley lab
Chromosome Replication Laboratory
: Publications

Publications

Displaying 1 - 6 of 6

Last updated : 19 April 2024 02:03

A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint

Authors (6)

Humberto Sánchez
Zhaowei Liu
Edo van Veen
Theo van Laar
John Diffley
Nynke H Dekker

Nature Communications

Published 23 October 2023

Crick labs

John Diffley

Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation

Authors (7)

Daniel Ramírez Montero
Humberto Sánchez
Edo van Veen
Theo van Laar
Belén Solano
John Diffley
Nynke H Dekker

Nature Communications

Published 14 April 2023

Crick labs

John Diffley

DNA replication origins retain mobile licensing proteins

Authors (8)

Humberto Sánchez
Kaley McCluskey
Theo van Laar
Edo van Veen
Filip M Asscher
Belén Solano
John Diffley
Nynke H Dekker

Nature Communications

Published 26 March 2021

Crick labs

John Diffley

Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome

Authors (12)

Panchali Goswami
Ferdos Abid Ali
Max E Douglas
Julia Locke
Andrew Purkiss
Agnieszka Janska
[...]
Anne Early
Andrea Nans
Alan MC Cheung
John Diffley
Alessandro Costa

Nature Communications

Published 29 November 2018

Crick labs/ facilities

Cryo-EM structure of a licensed DNA replication origin

Authors (7)

Nature Communications

Published 21 December 2017

Crick labs/ facilities

Cdt1 stabilizes an open MCM ring for helicase loading

Authors (10)

Jordi Frigola
Jun He
Kerstin Kinkelin
Val Pye
Ludovic Renault
Max E Douglas
Dirk Remus
Peter Cherepanov
Alessandro Costa
John Diffley

Nature Communications

Published 23 June 2017

Crick labs/ facilities