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Breadcrumb John Diffley Diffley lab Chromosome Replication Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Members A cartoon of a section of chromatin in the nucleus with replication origins in three different states. Toggle to view hero caption PublicationsYear published (-)2017 (4) Facet Year publishedResearch topicsBiochemistry & Proteomics (4)Cell Biology (4)Cell Cycle & Chromosomes (4)Genetics & Genomics (4)Genome Integrity & Repair (4)Model Organisms (4)Structural Biology & Biophysics (4)Imaging (3)Chemical Biology & High Throughput (1)Infectious Disease (1) Facet Research topicsPublication typeJournal article (4)Primary research (4) Facet Publication typeJournalNature Communications (2)Proceedings of the National Academy of Sciences of the United States of America (1)Science (1) Facet Journal Publications Displaying 1 - 4 of 4Last updated : 28 March 2024 03:22 Cryo-EM structure of a licensed DNA replication origin Authors (7) Ferdos Abid Ali Max E DouglasJulia LockeVal PyeAndrea NansJohn DiffleyAlessandro Costa Nature Communications Published 21 December 2017 Crick labs/ facilitiesPeter RosenthalJohn DiffleyAlessandro CostaPeter Cherepanov Structural BiologyElectron MicroscopyFull details Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading Authors (2)Gideon CosterJohn Diffley Science Published 21 July 2017 Crick labs/ facilitiesJohn DiffleyBioinformatics and BiostatisticsFull details Cdt1 stabilizes an open MCM ring for helicase loading Authors (10) Jordi Frigola Jun He Kerstin KinkelinVal Pye Ludovic Renault Max E Douglas Dirk RemusPeter CherepanovAlessandro CostaJohn Diffley Nature Communications Published 23 June 2017 Crick labs/ facilitiesJohn DiffleyAlessandro CostaPeter Cherepanov ProteomicsFull details CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome Authors (8) Jin Chuan Zhou Agnieszka Janska Panchali Goswami Ludovic Renault Ferdos Abid Ali Abhay KotechaJohn DiffleyAlessandro Costa Proceedings of the National Academy of Sciences of the United States of America Published 18 April 2017 Crick labs/ facilitiesJohn DiffleyAlessandro CostaStructural BiologyFermentationElectron MicroscopyFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Cryo-EM structure of a licensed DNA replication origin Authors (7) Ferdos Abid Ali Max E DouglasJulia LockeVal PyeAndrea NansJohn DiffleyAlessandro Costa Nature Communications Published 21 December 2017 Crick labs/ facilitiesPeter RosenthalJohn DiffleyAlessandro CostaPeter Cherepanov Structural BiologyElectron MicroscopyFull details
Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading Authors (2)Gideon CosterJohn Diffley Science Published 21 July 2017 Crick labs/ facilitiesJohn DiffleyBioinformatics and BiostatisticsFull details
Cdt1 stabilizes an open MCM ring for helicase loading Authors (10) Jordi Frigola Jun He Kerstin KinkelinVal Pye Ludovic Renault Max E Douglas Dirk RemusPeter CherepanovAlessandro CostaJohn Diffley Nature Communications Published 23 June 2017 Crick labs/ facilitiesJohn DiffleyAlessandro CostaPeter Cherepanov ProteomicsFull details
CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome Authors (8) Jin Chuan Zhou Agnieszka Janska Panchali Goswami Ludovic Renault Ferdos Abid Ali Abhay KotechaJohn DiffleyAlessandro Costa Proceedings of the National Academy of Sciences of the United States of America Published 18 April 2017 Crick labs/ facilitiesJohn DiffleyAlessandro CostaStructural BiologyFermentationElectron MicroscopyFull details