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Breadcrumb John Diffley Diffley lab Chromosome Replication Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Members A cartoon of a section of chromatin in the nucleus with replication origins in three different states. Toggle to view hero caption PublicationsYear published2023 (4)2022 (4)2021 (15)2020 (1)2019 (3)2018 (2)2017 (4)2016 (5)2015 (3)2014 (3)2013 (4)2012 (3)2011 (4)2010 (3) Facet Year publishedResearch topicsBiochemistry & Proteomics (39)Cell Cycle & Chromosomes (39)Genetics & Genomics (39)Genome Integrity & Repair (39)Model Organisms (39)Cell Biology (38)Structural Biology & Biophysics (38)Chemical Biology & High Throughput (13)Imaging (9)Infectious Disease (8)Computational & Systems Biology (7)Immunology (7)Synthetic Biology (5)Gene Expression (1)Metabolism (1)Tumour Biology (1) Facet Research topicsPublication typeJournal article (58)Primary research (43)Review (9)Commentary (4)Method (2) Facet Publication typeJournalBiochemical Journal (8)Nature (6)Nature Communications (6)Current Biology (5)Molecular Cell (4)EMBO Journal (3)Science (3)Cell (2)eLife (2)Annual Review of Biochemistry (1)Cold Spring Harbor Perspectives in Biology (1)Cold Spring Harbor Symposia on Quantitative Biology (1)Current Opinion in Cell Biology (1)Current Opinion in Structural Biology (1)DNA Repair (1)EMBO Molecular Medicine (1)Genetics (1)Journal of Biological Chemistry (1)Journal of Cell Science (1)Methods (1)Methods and Protocols (1)Methods in Enzymology (1)Nature Structural and Molecular Biology (1)Nucleic Acids Research (1)Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (1)Proceedings of the National Academy of Sciences of the United States of America (1)RSC Advances: an international journal to further the chemical sciences (1)Scientific Reports (1) Facet Journal Publications Displaying 41 - 58 of 58Last updated : 28 March 2024 03:07 Checkpoint-dependent RNR induction promotes fork restart after replicative stress Authors (4) Esther C MorafraileJohn Diffley José Antonio Tercero Mónica Segurado Scientific Reports Published 20 January 2015 Crick labsJohn DiffleyFull details Origin licensing requires ATP binding and hydrolysis by the MCM replicative helicase Authors (5) Gideon Coster Jordi Frigola Fabienne Beuron Edward P MorrisJohn Diffley Molecular Cell Published 4 September 2014 Crick labsJohn DiffleyFull details DNA replication and oncogene-induced replicative stress Authors (2) Stephanie A HillsJohn Diffley Current Biology Published 19 May 2014 Crick labsJohn DiffleyFull details Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication Authors (6) Kin Fan On Fabienne BeuronDavid FrithBram Snijders Edward P MorrisJohn Diffley EMBO Journal Published 18 March 2014 Crick labs/ facilitiesJohn DiffleyProteomicsFull details Regulating DNA replication in Eukarya Authors (3) Khalid Siddiqui Kin Fan OnJohn Diffley Cold Spring Harbor Perspectives in Biology Published 1 September 2013 Crick labsJohn DiffleyFull details Identification of a heteromeric complex that promotes DNA replication origin firing in human cells Authors (3) Dominik Boos Mona YekezareJohn Diffley Science Published 24 May 2013 Crick labsJohn DiffleyFull details ATPase-dependent quality control of DNA replication origin licensing Authors (4) Jordi Frigola Dirk Remus Amina MehannaJohn Diffley Nature Published 21 March 2013 Crick labsJohn DiffleyFull details Controlling DNA replication origins in response to DNA damage - inhibit globally, activate locally Authors (3) Mona Yekezare Belén Gómez-GonzálezJohn Diffley Journal of Cell Science Published 15 March 2013 Crick labsJohn DiffleyFull details Activation of the replicative DNA helicase: breaking up is hard to do Authors (3) Dominik Boos Jordi FrigolaJohn Diffley Current Opinion in Cell Biology Published 1 June 2012 Crick labsJohn DiffleyFull details Pre-replicative complex assembly with purified proteins Authors (2) Amina MehannaJohn Diffley Methods Published 1 June 2012 Crick labsJohn DiffleyFull details Replication timing: the early bird catches the worm Authors (2) Max E DouglasJohn Diffley Current Biology Published 7 February 2012 Crick labsJohn DiffleyFull details Quality control in the initiation of eukaryotic DNA replication Authors (1)John Diffley Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences Published 27 December 2011 Crick labsJohn DiffleyFull details Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment Authors (2) Boris PfanderJohn Diffley EMBO Journal Published 14 December 2011 Crick labsJohn DiffleyFull details Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans Authors (7) Dominik Boos Luis Sanchez-Pulido Mathieu Rappas Laurence H Pearl Antony W Oliver Chris P PontingJohn Diffley Current Biology Published 12 July 2011 Crick labs/ facilitiesJohn DiffleyCell ServicesFull details Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes Authors (7) J Baxter N Sen V López Martínez ME Monturus De Carandini JB SchvartzmanJohn Diffley L Aragón Science Published 11 March 2011 Crick labsJohn DiffleyFull details Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation Authors (2) Philip ZegermanJohn Diffley Nature Published 23 September 2010 Crick labsJohn DiffleyFull details Homology explains the functional similarities of Treslin/Ticrr and Sld3 Authors (3) Luis Sanchez-PulidoJohn Diffley Chris P Ponting Current Biology Published 22 June 2010 Crick labsJohn DiffleyFull details The many faces of redundancy in DNA replication control Authors (1)John Diffley Cold Spring Harbor Symposia on Quantitative Biology Published 1 January 2010 Crick labsJohn DiffleyFull details Pagination First page First Previous page Previous Page 1 Page 2 Current page 3 Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Checkpoint-dependent RNR induction promotes fork restart after replicative stress Authors (4) Esther C MorafraileJohn Diffley José Antonio Tercero Mónica Segurado Scientific Reports Published 20 January 2015 Crick labsJohn DiffleyFull details
Origin licensing requires ATP binding and hydrolysis by the MCM replicative helicase Authors (5) Gideon Coster Jordi Frigola Fabienne Beuron Edward P MorrisJohn Diffley Molecular Cell Published 4 September 2014 Crick labsJohn DiffleyFull details
DNA replication and oncogene-induced replicative stress Authors (2) Stephanie A HillsJohn Diffley Current Biology Published 19 May 2014 Crick labsJohn DiffleyFull details
Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication Authors (6) Kin Fan On Fabienne BeuronDavid FrithBram Snijders Edward P MorrisJohn Diffley EMBO Journal Published 18 March 2014 Crick labs/ facilitiesJohn DiffleyProteomicsFull details
Regulating DNA replication in Eukarya Authors (3) Khalid Siddiqui Kin Fan OnJohn Diffley Cold Spring Harbor Perspectives in Biology Published 1 September 2013 Crick labsJohn DiffleyFull details
Identification of a heteromeric complex that promotes DNA replication origin firing in human cells Authors (3) Dominik Boos Mona YekezareJohn Diffley Science Published 24 May 2013 Crick labsJohn DiffleyFull details
ATPase-dependent quality control of DNA replication origin licensing Authors (4) Jordi Frigola Dirk Remus Amina MehannaJohn Diffley Nature Published 21 March 2013 Crick labsJohn DiffleyFull details
Controlling DNA replication origins in response to DNA damage - inhibit globally, activate locally Authors (3) Mona Yekezare Belén Gómez-GonzálezJohn Diffley Journal of Cell Science Published 15 March 2013 Crick labsJohn DiffleyFull details
Activation of the replicative DNA helicase: breaking up is hard to do Authors (3) Dominik Boos Jordi FrigolaJohn Diffley Current Opinion in Cell Biology Published 1 June 2012 Crick labsJohn DiffleyFull details
Pre-replicative complex assembly with purified proteins Authors (2) Amina MehannaJohn Diffley Methods Published 1 June 2012 Crick labsJohn DiffleyFull details
Replication timing: the early bird catches the worm Authors (2) Max E DouglasJohn Diffley Current Biology Published 7 February 2012 Crick labsJohn DiffleyFull details
Quality control in the initiation of eukaryotic DNA replication Authors (1)John Diffley Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences Published 27 December 2011 Crick labsJohn DiffleyFull details
Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment Authors (2) Boris PfanderJohn Diffley EMBO Journal Published 14 December 2011 Crick labsJohn DiffleyFull details
Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans Authors (7) Dominik Boos Luis Sanchez-Pulido Mathieu Rappas Laurence H Pearl Antony W Oliver Chris P PontingJohn Diffley Current Biology Published 12 July 2011 Crick labs/ facilitiesJohn DiffleyCell ServicesFull details
Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes Authors (7) J Baxter N Sen V López Martínez ME Monturus De Carandini JB SchvartzmanJohn Diffley L Aragón Science Published 11 March 2011 Crick labsJohn DiffleyFull details
Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation Authors (2) Philip ZegermanJohn Diffley Nature Published 23 September 2010 Crick labsJohn DiffleyFull details
Homology explains the functional similarities of Treslin/Ticrr and Sld3 Authors (3) Luis Sanchez-PulidoJohn Diffley Chris P Ponting Current Biology Published 22 June 2010 Crick labsJohn DiffleyFull details
The many faces of redundancy in DNA replication control Authors (1)John Diffley Cold Spring Harbor Symposia on Quantitative Biology Published 1 January 2010 Crick labsJohn DiffleyFull details