Publications

Structural basis of lentiviral subversion of a cellular protein degradation pathway

Authors (8)

David Schwefel
Harriet CT Groom
Virginie C Boucherit
Evangelos Christodoulou
Philip Walker
Jonathan Stoye
Kate Bishop
Ian Taylor

Nature

Published 15 December 2014

Crick labs/ facilities

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Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice

Authors (11)

David C Goldstone
Philip Walker
Lesley Calder
Peter J Coombs
Joshua Kirkpatrick
Neil J Ball
Laura Hilditch
Melvyn Yap
Peter Rosenthal
Jonathan Stoye
Ian Taylor

Proceedings of the National Academy of Sciences of the United States of America

Published 1 July 2014

Crick labs/ facilities

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HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes

Authors (10)

Daria Brinzevich
George Young
Robert Sebra
Juan Ayllon
Susan M Maio
Gintaras Deikus
Benjamin K Chen
Ana Fernandez-Sesma
Viviana Simon
Lubbertus CF Mulder

Journal of Virology

Published 19 March 2014

Crick labs

Jonathan Stoye

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Evolution of the retroviral restriction gene Fv1: inhibition of non-MLV retroviruses

Authors (4)

Melvyn Yap
Emily Colbeck
Scott A Ellis
Jonathan Stoye

PLOS Pathogens

Published 1 March 2014

Crick labs

Jonathan Stoye

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Apparent effect of rabbit endogenous lentivirus type K acquisition on retrovirus restriction by lagomorph Trim5αs

Authors (2)

Philosophical Transactions of the Royal Society B: Biological Sciences

Published 19 September 2013

Crick labs

Jonathan Stoye

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Capsid-binding retrovirus restriction factors: discovery, restriction specificity and implications for the development of novel therapeutics

Authors (2)

Marta Sanz-Ramos
Jonathan Stoye

Journal of General Virology

Published 11 September 2013

Crick labs

Jonathan Stoye

Full details

Our viral inheritance

Authors (2)

RA Weiss
Jonathan Stoye

Science

Published 17 May 2013

Crick labs

Jonathan Stoye

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A unique spumavirus Gag N-terminal domain with functional properties of orthoretroviral matrix and capsid

Authors (11)

DC Goldstone
TG Flower
NJ Ball
M Sanz-Ramos
Melvyn Yap
Roksana Ogrodowicz
N Stanke
J Reh
D Lindemann
Jonathan Stoye
Ian Taylor

PLOS Pathogens

Published 1 May 2013

Crick labs/ facilities

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TRIM proteins and the innate immune response to viruses

Authors (2)

Advances in Experimental Medicine and Biology

Published 5 March 2013

Crick labs

Jonathan Stoye

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A comparison of murine leukemia viruses that escape from human and rhesus macaque TRIM5αs

Authors (2)

Sadayuki Ohkura
Jonathan Stoye

Journal of Virology

Published 1 January 2013

Crick labs

Jonathan Stoye

Full details

Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis

Authors (3)

BioEssays

Published 1 January 2013

Crick labs

Full details

Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice

Authors (3)

Retrovirology

Published 22 March 2012

Crick labs

Full details

Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection

Authors (6)

George Young
MJ Ploquin
U Eksmond
M Wadwa
Jonathan Stoye
George Kassiotis

PLOS Pathogens

Published 1 January 2012

Crick labs

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Resurrection of endogenous retroviruses in antibody-deficient mice

Authors (6)

George Young
Urszula Eksmond
Rosalba Salcedo
Lena Alexopoulou
Jonathan Stoye
George Kassiotis

Nature

Published 1 January 2012

Crick labs

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Studies of endogenous retroviruses reveal a continuing evolutionary saga

Authors (1)

Jonathan Stoye

Nature Reviews Microbiology

Published 1 January 2012

Crick labs

Jonathan Stoye

Full details

Tripartite-motif proteins and innate immune regulation

Authors (4)

FW McNab
R Rajsbaum
Jonathan Stoye
Anne O'Garra

Current Opinion in Immunology

Published 3 December 2011

Crick labs

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Binding of more than one Tva800 molecule is required for ASLV-A entry

Authors (4)

ER Gray
CJR Illingworth
JM Coffin
Jonathan Stoye

Retrovirology

Published 18 November 2011

Crick labs

Jonathan Stoye

Full details

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

Authors (15)

DC Goldstone
V Ennis-Adeniran
JJ Hedden
HCT Groom
GI Rice
E Christodoulou
[...]
Luiz Pedro Carvalho
Jonathan Stoye
YJ Crow
Ian Taylor
M Webb

Nature

Published 6 November 2011

Crick labs/ facilities

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Unique spectrum of activity of prosimian TRIM5α against exogenous and endogenous retroviruses

Authors (11)

N Rahm
Melvyn Yap
J Snoeck
V Zoete
M Munoz
U Radespiel
E Zimmermann
O Michielin
Jonathan Stoye
A Ciuffi
A Telenti

Journal of Virology

Published 1 May 2011

Crick labs

Jonathan Stoye

Full details

Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1

Authors (6)

L Hilditch
R Matadeen
DC Goldstone
Peter Rosenthal
Ian Taylor
Jonathan Stoye

Proceedings of the National Academy of Sciences of the United States of America

Published 21 March 2011

Crick labs

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: Publications

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Publications

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Structural basis of lentiviral subversion of a cellular protein degradation pathway

Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice

HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes

Evolution of the retroviral restriction gene Fv1: inhibition of non-MLV retroviruses

Apparent effect of rabbit endogenous lentivirus type K acquisition on retrovirus restriction by lagomorph Trim5αs

Capsid-binding retrovirus restriction factors: discovery, restriction specificity and implications for the development of novel therapeutics

Our viral inheritance

A unique spumavirus Gag N-terminal domain with functional properties of orthoretroviral matrix and capsid

TRIM proteins and the innate immune response to viruses

A comparison of murine leukemia viruses that escape from human and rhesus macaque TRIM5αs

Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis

Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice

Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection

Resurrection of endogenous retroviruses in antibody-deficient mice

Studies of endogenous retroviruses reveal a continuing evolutionary saga

Tripartite-motif proteins and innate immune regulation

Binding of more than one Tva800 molecule is required for ASLV-A entry

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

Unique spectrum of activity of prosimian TRIM5α against exogenous and endogenous retroviruses

Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1

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Research topics

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