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Breadcrumb Julian Downward Downward lab Oncogene Biology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Lab news Mass cytometry images of carcinogen induced lung tumours in mice. Toggle to view hero caption PublicationsYear published2020 (1)2018 (1) Facet Year publishedResearch topicsChemical Biology & High Throughput (2)Gene Expression (2)Genetics & Genomics (2)Model Organisms (2)Signalling & Oncogenes (2)Tumour Biology (2)Computational & Systems Biology (1)Genome Integrity & Repair (1) Facet Research topicsPublication typeJournal article (2)Primary research (2) Facet Publication typeJournal (-)EMBO Molecular Medicine (2) Facet Journal Publications Displaying 1 - 2 of 2Last updated : 29 March 2024 03:15 Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer Authors (7)Davide ZecchinChristopher MooreFanis Michailidis Stuart HorswellSareena RanaMichael HowellJulian Downward EMBO Molecular Medicine Published 7 August 2020 Crick labs/ facilitiesJulian DownwardHigh Throughput ScreeningBioinformatics and BiostatisticsExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details An oligoclonal antibody durably overcomes resistance of lung cancer to third-generation EGFR inhibitors Authors (20) Maicol Mancini Hilah Gal Nadège Gaborit Luigi Mazzeo Donatella Romaniello Tomer Meir Salame[...] Emilie BousquetJulian Downward Antonio Maraver Valery Krizhanovsky Yosef Yarden EMBO Molecular Medicine Published 6 December 2018 Crick labsJulian DownwardFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer Authors (7)Davide ZecchinChristopher MooreFanis Michailidis Stuart HorswellSareena RanaMichael HowellJulian Downward EMBO Molecular Medicine Published 7 August 2020 Crick labs/ facilitiesJulian DownwardHigh Throughput ScreeningBioinformatics and BiostatisticsExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details
An oligoclonal antibody durably overcomes resistance of lung cancer to third-generation EGFR inhibitors Authors (20) Maicol Mancini Hilah Gal Nadège Gaborit Luigi Mazzeo Donatella Romaniello Tomer Meir Salame[...] Emilie BousquetJulian Downward Antonio Maraver Valery Krizhanovsky Yosef Yarden EMBO Molecular Medicine Published 6 December 2018 Crick labsJulian DownwardFull details